Download - Seminar assignment
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Seminar assignment
• Handed out at course start
• Group work/individual assessment
• Research based aspects, requires independent work
• Obtain appropriate information- lectures, discussions, web, articles ..…
• Time scheduled to prepare answer
• Presentation of assignment in seminar format:Groups 3, 4, 5 + 6 Friday 19th NovemberGroups 1 + 2 Thursday 25th November
• Grading = pass / fail
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Seminar assignmentWhy?
• Training for the exam
• Attain “core” knowledge
• Apply knowledge from previous courses
• Sort out misunderstandings
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1. How could lipid accumulation in the liver be due to defects in adipose tissue?
Seminar assignment
Cusi K. Curr Diab Rep (2010) 10: 306-315
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Seminar assignment
Association between liver fat accumulation and a single nucleotide polymorphism (SNP) located in the promoter of gene X in a putative binding site for peroxisome proliferator activated receptors (PPARs).
2. Describe the molecular mechanism of action of PPARs
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Seminar assignment
3. Calculate the frequency of each of the alleles
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Seminar assignment
Your task is to design three complementary research studies in order to explore the medical importance of the SNP Study 1. A confirmative human study of your preliminary findings that is population based (~5000 individuals).
Study 2. An individually based human study consisting of ~50 individuals that could test whether drugs could influence the degree of hepatosteatosis depending on the SNP in gene X Study 3. Design and describe an in vitro study that will investigate the putative underlying molecular mechanisms using commercially available cell lines
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Seminar assignment
• Handed out at course start
• Group work/individual assessment
• Research based aspects, requires independent work
• Obtain appropriate information- lectures, discussions, web, articles ..…
• Time scheduled to prepare answer
• Presentation of assignment in seminar format:Groups 3, 4, 5 + 6 Friday 19th NovemberGroups 1 + 2 Thursday 25th November
• Grading = pass / fail
![Page 8: Seminar assignment](https://reader036.vdocument.in/reader036/viewer/2022062322/56815037550346895dbe34fc/html5/thumbnails/8.jpg)
Time in schedule for Groups 3 + 4to work with seminar assignment
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Group 3:9.00-10.30Addison
Group 4:10.30-12.00Addison
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Time in schedule for Groups 5 + 6to work with seminar assignment
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Group 5:9.00-10.30Einthoven
Group 6:10.30-12.00Einthoven
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Time in schedule for Groups 1 + 2 to work with seminar assignment
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Group 1:10.00-11.30Addison
Group 2:10.00-11.30Einthoven
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Seminar assignment
On demand – support session
Wednesday Nov 10, 3 pm
Register before Tuesday Nov 9 to:
[email protected] and [email protected]
Hand in specific questions
What it is that needs to be clarified