Download - SEPTEMBER 30, 2007
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2007 BOARD OF DIRECTORS
CHRIS SULLIVAN, CHAIRMAN
DAVID J. GURY, VICE CHAIRMAN · ANDY CRAWFORD
DR. PAMELLA DANA · WILLIAM P. FOLEY · DR. EDWARD
GONZALEZ · RUBEN KING-SHAW, JR. · JAMES E. MCCOLLUM
DR. JOSEPH J. THOMAS · DR. DALE BRILL, EX-OFFICIO
JENNI GARRISON, PROJECT DIRECTOR
SCRIPPS FLORIDA FUNDING CORPORATION
FOURTH ANNUAL REPORT
FOR YEAR ENDED
SEPTEMBER 30, 2007
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Scripps Florida Funding Corporation 1
Annual Report 2007
Scripps Florida Funding Corporation Fourth Annual Report For Year Ended September 30, 2007 INTRODUCTION Florida Statute 288.955 (the “Enabling Statute”) created Scripps Florida Funding
Corporation (“SFFC”) to facilitate the establishment and operation of a biomedical
research institution for the purposes of enhancing education and research and promoting
economic development and diversity. In addition, the Enabling Statute charged SFFC
with the obligation to assure the compliance by The Scripps Research Institute (“TSRI”)
with the Enabling Statute and the agreement between SFFC and TSRI (the “Operating
and Funding Agreement”). The Enabling Statute provides that SFFC shall prepare or
obtain certain reports, audits, and evaluations of TSRI’s compliance with the
performance expectations and disbursement conditions contained in the Enabling Statute.
As such, SFFC is submitting this SFFC Annual Report to the Governor, the President of
the Senate, and the Speaker of the House, as required by the Enabling Statute to be
submitted by December 1 of each year. This SFFC Annual Report addresses the
activities and outcomes of SFFC and Scripps Florida (“Scripps”) for the fiscal year ended
September 30, 2007 (“Fiscal 2007”). The Scripps Florida Annual Report addressed the
activities and outcomes of Scripps Florida for the year ended June 30, 2007, and SFFC
received the Scripps Florida Annual Report on August 28, 2007. The information in the
Scripps Florida Annual Report was informally updated for this SFFC Annual Report.
This SFFC Fourth Annual Report is presented in two parts: first, a summary that
highlights the substantial events that have occurred during the year ended September 30,
2007; and second, an itemized report that corresponds with the applicable sections of the
Enabling Statute.
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Scripps Florida Funding Corporation 2
Annual Report 2007
About the Scripps Florida Funding Corporation In November 2003, Governor Bush signed into law an historic piece of legislation that
laid the framework for The Scripps Research Institute to expand its world-renowned
scientific research and endeavors into Florida. The bill, passed by the Florida Legislature
during special session, provided a one-time investment of $310 million from federal
economic stimulus monies to create Scripps Florida and pay certain of its expenses for
the first seven years, specifically salaries and equipment purchases. In June 2006, The
Scripps Research Institute revised the Scripps Florida business plan and scheduled
investment from the State, which expanded their grant funding to ten years, or through
2014.
To oversee the investment and spending of the State’s investment in Scripps Florida, the
Florida Legislature created the Scripps Florida Funding Corporation, hereto referred to as
SFFC, a nonprofit entity comprised of a nine-member Board. The role of SFFC was
enunciated by Governor Bush:
“My vision for this board is that it manages the financial portion of our
partnership, but lets Scripps do what it does best – conduct biomedical research.”
This report serves to report on both the requirements and the aspirations as set forth by
the State in the Operating and Funding Agreement with Scripps.
About the Scripps Research Institute The Scripps Research Institute, headquartered in La Jolla, California, in 15 buildings on
22 acres overlooking the Pacific Ocean, is one of the world's largest independent, non-
profit biomedical research organizations. It stands at the forefront of basic biomedical
science that seeks to comprehend the most fundamental processes of life. Scripps
Research is internationally recognized for its research into immunology, molecular and
cellular biology, chemistry, neurosciences, autoimmune, cardiovascular, and infectious
diseases, and synthetic vaccine development. Established in its current configuration in
1961, it employs approximately 3,000 scientists, postdoctoral fellows, scientific and other
technicians, doctoral degree graduate students and administrative and technical support
personnel.
About Scripps Florida
Scripps Florida, a 364,000 square-foot, state-of-the-art biomedical research facility, is
under construction in the Town of Jupiter in Palm Beach County, Florida. Scripps
Florida now operates with approximately 220 scientists, technicians, and administrative
staff at two temporary laboratory facilities, together comprising 74,000 square feet, on
the Florida Atlantic University campus in Jupiter. Scripps Florida focuses on basic
biomedical science, drug discovery and technology development.
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Scripps Florida Funding Corporation 3
Annual Report 2007
Scripps Florida Funding Corporation Board of Directors
Of the nine-member Board of Directors, three Directors are appointed by each of the
Governor, House Speaker, and the Senate President. The terms of the directors initially
ranged from one to four years and expire on a staggered schedule
Governor Bush appointed Dr. Pamella Dana, of Destin, on January 1, 2007 for a term
ending on November 13, 2008. Dr. Dana previously served the Board of Directors as an
ex-officio member, while serving as the Governor’s Director of the Office of Tourism,
Trade and Economic Development (“OTTED”).
On September 19, 2007, Governor Charlie Crist named Dr. Dale Brill as the Director of
OTTED. Dr. Brill joined the Board of Directors at that time to serve in an ex-officio
capacity.
Other SFFC Board of Directors members who served during the fiscal year include: Mr.
Chris Sullivan, Chairman; Mr. David Gury, Vice-Chairman; Mr. F. Andy Crawford; Mr.
James McCollum; Dr. Edward Gonzalez; Mr. William Foley; Mr. Ruben King-Shaw, Jr.;
and Dr. Joseph Thomas.
SFFC Board of Directors and Committee Meetings
From October 1, 2006 through September 30, 2007, the SFFC Board of Directors
(“BOD”) held three meetings, one of which was in-person. At the November 28, 2006
Board of Director’s meeting, the Board unanimously elected Mr. Chris Sullivan as
Chairman and Mr. David Gury as Vice-Chairman. Their terms began in January 2007.
The previous Chair, Mr. Marshall Criser, Jr., resigned his Board position on November 2,
2006, and served until the Governor appointed his successor. On January 22, 2007 the
Board approved the 2007 SFFC budget and reorganized the committee structure of the
Board.
In-Person Board of Directors Meeting
On March 9, 2007, the members of the Scripps Florida Funding Corporation
Board met at the Jupiter campus of Florida Atlantic University, adjacent to the
Scripps Florida campus. This meeting involved the annual grant request and was
planned in conjunction of the dedication of the Scripps Florida campus. After an
Audit Committee meeting, the Board joined over 400 Scripps Florida employees
and guests at the permanent facility construction site. Dr. Richard Lerner thanked
the people and leaders of Palm Beach County and the State of Florida. Also
attending the dedication were Governor Crist, former Governor Bush and Mr.
Marshall Criser, who was recognized for his leadership during the first three years
of Scripps Florida’s development. After a luncheon, the Board reconvened at the
FAU facility to hold its meeting and the agenda included updates from the Audit
Committee and the 2007 annual grant request which was approved unanimously.
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Scripps Florida Funding Corporation 4
Annual Report 2007
Committee Meetings
The three Committees of the SFFC are the Investment Committee, the Audit
Committee and the Reports Committee. From October 1, 2006 through
September 30, 2007, the Investment Committee held two teleconference
meetings. The majority of the Investment Committee’s time dealt with the review
of the quarterly reports from the State Board of Administration (“SBA”), where
the balance of the State’s $310 million investment in Scripps Florida is held. Mr.
Michael Lombardi, the SBA’s Representative, participates in the Investment
Committee meetings and informs the Committee of the actions undertaken by the
SBA. During this fiscal year, the Audit Committee participated in three
teleconference meetings and one in-person meeting to review, accept, and discuss
the financial reports provided by TSRI and Scripps Florida, which include: the
quarterly unaudited financials for TSRI and Scripps Florida; the yearly Audit
reports for TSRI and Scripps Florida; and the yearly budget for Scripps Florida.
The Audit Committee also engages the auditor to conduct both the audit of SFFC
and the compliance audit of Scripps Florida and reviews, accepts, discusses and
approves the auditor’s reports, the SFFC budget and the SFFC tax return. The
Reports Committee received drafts of the third annual report over the course of
October and November 2006 in order to review the content of the annual report
before it was submitted to the full Board of Directors for final approval.
Scripps Florida Facilities
Scripps Florida continues to operate out of two temporary facilities adjacent to Florida
Atlantic University’s Honors campus in Jupiter, Florida. Together, the facilities provide
74,000 square feet of laboratory and work space. Scripps Florida’s external affairs and
development personnel remain in Scripps Florida’s downtown West Palm Beach office.
The permanent campus of Scripps Florida in the Town of Jupiter is 100 acres total and is
comprised of the following: 30 acres for Scripps Florida’s three permanent buildings,
totaling 340,000 square feet, on FAU’s Jupiter campus; and 70 acres for Phase II (Scripps
Florida expansion) across the street from FAU on the Briger property. Additionally, the
Briger owners agreed to restrict 100 acres for future research and development spin-off
use.
In October 2006, site preparation for the permanent facility began. Underground utilities
were brought to the site in November and December. Foundations were poured in
February of 2007 and vertical construction began shortly thereafter. By the end of
August, the shell construction for all three buildings was complete. The construction
team is currently on schedule to complete the permanent facilities in the fourth quarter of
2008, possibly ahead of schedule because a hurricane buffer built into the schedule was
not needed.
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Scripps Florida Funding Corporation 5
Annual Report 2007
Architectural rendering of Scripps Florida permanent campus
Below, aerial photos of Scripps Florida site, dated December 26, 2006; July 26, 2007;
and October 24, 2007.
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Scripps Florida Funding Corporation 6
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Scripps Florida Funding Corporation 7
Annual Report 2007
Scripps Florida Employees
As of September 30, 2007, Scripps Florida employed 223 people. The new employees at
Scripps Florida include several scientists and other personnel with notable resumes, as
described below.
In July 2007, internationally recognized chemist Roy A. Periana, Ph.D., joined Scripps Florida as a professor of chemistry. “Professor Periana's expertise will add substantial value to our ongoing efforts in
developing more efficient synthetic methodologies in chemistry," said Scripps Research
President Richard A. Lerner, M.D., himself a chemist. "His research will enhance our
ability to make new medicines to benefit human health. In addition, it will allow Scripps
Florida to move in a timely manner into the critical areas of energy and alternative fuels,
a stated interest of the Governor Charlie Crist and the people of Florida. We expect
strong and enthusiastic support for this important research from both philanthropic and
government organizations."
Professor Periana is a graduate of the University of Michigan and obtained his Ph.D.
from the University of California, Berkeley, working with Professor Robert Bergman.
His background ranges from co-founder of Catalytica Advanced Technologies in the
Silicon Valley to, most recently, professor of chemistry at the University of Southern
California and its Loker Hydrocarbon Research Institute.
He is a world leader in the chemistry of the carbon-hydrogen (CH) bond and coordination
catalysis, a field in which he was one of the 20th century's original investigators.
Professor Periana has a strong publication record highlighted by three publications in
Science, and substantial funding from both industrial and government sources.
In addition to research on the CH bond, Dr. Periana's focus will be on the five small
molecules that provide the bulk of energy and materials on Earth: methane (CH4),
oxygen (O2), nitrogen (N2), water (H2O) and carbon dioxide (CO2).
Will Melton was named Vice President of Development for Scripps Florida in early 2007. Prior to arriving at Scripps Florida, Mr. Melton spent five years as Vice President for
Institutional Advancement at the Rhode Island School of Design, preceded by eight years
as Vice President for External Affairs at Middleburg College. He also served for seven
years at Yale University as director of Development for the Yale School of Medicine and
the Yale-New Haven Hospital.
A graduate of the University of Virginia, Mr. Melton has served on the Boards of
Northfield Mount Herman School, the New Haven Symphony Orchestra and the Urban
League of Greater New Haven.
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Annual Report 2007
Dr. Philippe Bois joined the Scripps Florida Department of Cancer Biology as an Assistant Professor in May 2007. Dr. Bois is taking a genetic approach, together with knock-out and knock-in technology,
to address fundamental questions about the origin, as well as the regulation and resolution
pathways, at recombination hotspots in the human genome. Dr. Bois studied at the
University of Paris 7, where he earned his bachelor’s, master’s and doctoral degrees.
In July 2007, Tina Izard, Ph.D., accepted the position of Associate Professor in the Scripps Florida Department of Cancer Biology Dr. Izard is studying the structural dynamics of signaling mediators of adhesion
junctions. Dr. Tina Izard is a graduate of the University of Basel in Switzerland and
received her Ph.D. at the University of Melbourne in 1994.
Scripps Florida Achievements for Fiscal Year 2007
In addition to progress on the permanent facility and the addition of remarkable talent
from across the country, Scripps Florida made several science and funding strides. From
October 1, 2006 through September 30, 2007, 13 patent applications were filed, naming a
Scripps Florida scientist as an inventor or co-inventor. Since inception, Scripps Florida
has been awarded 41 research grants totaling $30.7 million from sources other than
SFFC, including the National Institutes of Health (“NIH”).
Some significant achievements this past year include:
Xcovery, Spin-off Company is Established
Scripps Florida’s first private drug-discovery start-up, Xcovery of West Palm
Beach, was announced in May 2007. The company was named one of the most
promising biotech companies by Fierce Biotech, a news publication that monitors
the industry. The company develops new therapeutic products addressing
indications in oncology and inflammation. Xcovery was financed by BioCatalyst
International, a venture capital firm with offices in West Palm Beach headed by
Sheridan Snyder, a former founder of Genzyme, Upstate Biotechnology and
Biotage. Scripps Florida scientist Dr. Chris Liang invented the technology at
Scripps Florida. He will continue to be actively involved in development of the
small molecule drug candidates upon which the technology is based.
Scripps’ Kellogg School of Science and Technology Graduates First Student
Scripps Florida has established a Ph.D. program as part of Scripps’ Kellogg
School of Science and Technology. There were nine graduate students enrolled in
the program during the 2006-07 academic year. The Florida branch of the
Scripps’ Kellogg school reached a milestone this year with the graduation of
Porino Va, the first graduate of the Florida program. Mr. Va completed his Ph.D.
degree in May 2007.
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Scripps Florida Funding Corporation 9
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The establishment of graduate education at
Scripps Florida was a key goal for the graduate
program and for Scripps Florida. In 2005, several
students (including Mr. Va) transferred to Scripps
Florida from the University of Michigan with
William Roush, professor and associate dean for
Florida graduate studies. In 2006, the Kellogg
School accepted its first new student to the
Florida campus and in the fall of 2007, two new
students began their graduate studies in Florida.
"I feel very fortunate to have the honor of being Professor Roush's first Scripps
Florida Ph.D. graduate," Mr. Va said in the days leading up to graduation. "The
facilities and the science being conducted at Scripps Florida are truly world-class.
It is really exciting to be a part of the genesis of a new research institution and I
am certain that a few years from now, Scripps Florida will be even more
recognizable for its novel discoveries in science."
After graduation, Mr. Va will go on to postdoctoral studies in the laboratory of
Scripps Research Professor Dale Boger.
The Scripps Research Institute Enters Major Collaboration with Pfizer
In March 2007, the Scripps Research Institute announced that it had entered into a
five-year research collaboration with Pfizer Global Research and Development to
advance scientific knowledge of uncured diseases and novel ways to treat them,
making full use of emerging technologies and resident talent from both
organizations. Under the terms of the agreement, Pfizer will pay Scripps
Research $100 million over a five-year period, during which scientists from Pfizer
and the Institute will work together to identify and perform specific projects of
mutual interest. Approximately 10% of awarded funds will be provided to
Scripps Florida. During fiscal 2007, approximately $3 million from the Pfizer
grant was directed to Scripps Florida.
Scripps and Pfizer will jointly study and evaluate therapeutic approaches for
diseases such as cancer, diabetes, and mental illnesses. They will develop new
tests to rapidly validate these new therapies for potential development as possible
novel treatment options that can gain regulatory approval for use in patients.
Pfizer will pay Scripps both milestone payments and royalties on therapeutic
compounds created through the collaboration. In addition, Pfizer will have the
first right to license many discoveries made at Scripps Research during the
agreement.
Scripps Florida Forms Molecular Therapeutics Department
In anticipation of Scripps Florida's continued expansion, The Scripps Research
Institute created a new academic department in 2007, the Department of
Molecular Therapeutics.
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"We will recruit faculty to the Department of Molecular Therapeutics capable of
utilizing the advanced drug discovery technology at Scripps Florida," said Patrick
Griffin, the new department's chair. "Our goal is to discover new chemical probes
that have immediate therapeutic implications."
Associate Professor Phil LoGrasso and his group were among those joining
Griffin and his team as the department's first members. The department now
numbers 15 faculty, senior scientists, staff scientists, and research associates.
Scripps Florida Collaborations During the year ended September 30, 2007, Scripps Florida maintained its collaborative
relationships with three Florida-based institutions – the Jupiter Medical Center, Dyadic
and IBM – and began a new partnership with another Florida university. Scripps Florida
executed a formal agreement with Nova Southeastern University, bringing its total
number of Joint Cooperation Agreements (“JCAs”) to six. JCAs streamline the scientific
collaboration process by including such provisions to make it easier to collaborate on
filing patents and to share revenues from commercialized innovations. Additionally,
Scripps scientists participated in 13 formal scientific meeting with colleagues at Florida
colleges and universities. See Appendix D, “Scripps Florida Outreach Activities” for a
detailed listing of these Collaborations and Scientific Meetings.
Update on Scripps Florida’s “Access to Technologies” Program
In 2007, Dr. Smith at the Burnham Institute for Medical Research and Dr. Teplitski at the
University of Florida began using the “Access to Technologies” program at Scripps
Florida. Launched in 2006, the program continues to invite scientists from Florida
universities and other academic research institutions to use state-of-the-art screening
technologies at Scripps Florida's facilities in Jupiter for qualifying projects. Access to
Scripps Florida's High Throughput Screening (“HTS”) operation, similar to that used
widely by the pharmaceutical industry, speeds up the process of discovering new drugs to
treat a variety of human illnesses. The technology, which is one of five in the country, is
primarily for users within the State of Florida, however, Scripps Florida scientists
collaborate with researchers at universities and institutes across the country.
Grants and Awards
To date, Scripps Florida researchers and scientists have been awarded over $30 million in
grants from sources other than the State of Florida. A few notable grants from this past
year include:
The Arthritis Foundation awarded a grant to Scripps Florida scientist Dr. Patrick
Griffin for research in rheumatoid arthritis.
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Office Depot awarded a grant to Doctors Pletcher, Busby, Conkright and
Wahlestedt to study Glyoxylase1 phosphorylation signaling in Autism, gene
regulation in DREB mutants, to identify FMR4 protein product and to identify the
differential protein expression during neuron development.
The Education and Outreach program for middle and high school students, led by
Deborah Leach-Scampavia, was awarded a grant from the William R. Kenan, Jr. Charitable Trust.
The Scripps Exhibit at the South Florida Science Museum received support in a
grant from Workforce Alliance, Inc.
Scripps Florida Workforce Recruitment Scripps Florida has extended workforce recruitment efforts to Florida’s higher education
institutions throughout the state. In fiscal 2007, Scripps Florida attended 15 institution
career fairs and expositions, in an effort to recruit employees from Florida colleges and
universities. Additionally, Scripps Florida recognizes the need to increase the number of
employees from backgrounds which are underrepresented in the sciences. To that end,
Scripps has been a regular participant in career fair activities at Florida A&M University,
as well as other historically black colleges and universities. In 2007, Scripps participated
in five career fairs at these colleges and universities and as a result of that effort, a recent
graduate of Florida A&M University is now an employee of Scripps Florida. See
Appendix D, “Scripps Florida Outreach Activities” for a detailed listing of the Workforce
Recruitment efforts.
Scripps Florida Educational Outreach
Scripps Florida continued to develop and grow its educational outreach programs by
seeding its programs further into the education community in Palm Beach County. Here
are a few of the outreach activities conducted by Scripps Florida in fiscal 2007.
Working with BioFlorida, the state’s bio-industry association,
Scripps Florida helped sponsor the 2006 and 2007 statewide
Bioscience Education and Career Expositions. The Expo is a
week-long event designed to develop interest and educational
opportunities in bioscience across Florida. Scripps Florida helped
develop a CD and DVD which was sent to every high school in
the State of Florida for use during the statewide Expo.
The Scripps Summer Intern Research Program gives rising
high school junior and senior students and their teachers an in-
depth exposure to scientific research. Interns work under direct
supervision of a Scripps scientist for six weeks, on projects that
emphasize the scientific process, research planning, bench experience, experimental
design, and data analysis.
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The intern program has been a successful and expanding Scripps Florida Education
Outreach component. The program graduated nine students and three high school
teachers in July 2007, an increase of three students from the prior year. Mentors for the
summer program include researchers from Genomics, Proteomics, Infectology, Cancer
Biology, Medicinal Chemistry, Synthetic Chemistry, Bioinformatics, and High
Throughput Screening (Robotics) Laboratories.
An added benefit enjoyed by participants in the intern program is the establishment of
ongoing relationships with Scripps Florida staff. Correspondence has been maintained
with the high school student and science teacher graduates, including letters of
recommendation for college applications and the provision of Bioscience resource
material for teacher classroom curriculum. In 2007, an unexpected and welcome bonus
has been the opportunity to offer part-time lab assistant positions in the Proteomics,
Cancer Biology and HTS laboratories to three student intern graduates.
The Scripps Florida-South Florida Science Museum Exhibit is in development to help
foster an understanding in the general public of the basic ties that exist between
biomedical research and human health. Toward that end, Scripps Florida has partnered
with the South Florida Science Museum in West Palm Beach to develop a permanent
exhibit. The theme of the exhibit “2000 – The Bioscience Century – 2100”, illustrates
how bioscience, as physical science did last century, is shaping our lives and our future.
The purpose of the exhibit is to educate and inform the museum visitor on the nature of
bioscience and its impact on career opportunities. The exhibit will be composed of video
stations and Plexiglas displays representing the “four pillars of science”; Biology,
Chemistry, Physics and Math. Each pillar will have a hands-on, interactive science
activity appealing to a broad range of visitors, a definition of the science, and examples
of its application in the field of bioscience. There will be three interactive video displays
in the exhibit; Biotechnology, Careers in Science, and Cell Biology. The exhibit is
projected for completion in the winter of 2007.
Scripps donated supplies and equipment to the museum for staff to offer the Science
Saturday course at the museum and Scripps is developing four follow-up lessons to the
Introduction to Science class in chemistry, physics, biology and math.
Scripps Florida continues its education outreach efforts by offering the Introduction to Science program to elementary and middle schools; inviting sophomore and junior high
school students to participate in the Science Saturday course; and offering opportunities
for Undergraduate Internships with Scripps Florida. See Appendix D, “Scripps Florida
Outreach Activities” for a detailed listing of the Educational Outreach efforts, and a
listing of the Student and Teacher interns for summer 2007.
The Scripps Florida Science Seminars
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The Scripps Florida Science Seminars – the Collaborative Speaker Series and the
“Frontiers in Science” seminars - focus on topics within the broad fields of biomedical
science, advanced technologies applied to biomedical research and drug discovery. The
Collaborative Speaker sessions are open to interested professionals within the Scripps
Florida and Florida scientific communities, while the “Frontiers in Science” seminars are
open to the public. Seminars are typically held every month and over a dozen seminars
were held during fiscal 2007. See Appendix D, “Scripps Florida Outreach Activities” for
a detailed listing of the Seminar Series.
Scripps Florida Business and Community Outreach Scripps Florida continued to connect with many business and community organizations
during fiscal 2007 by participating in meetings facilitated by local business and
government agencies, such as the Palm Beach County Business Development Board,
regional Chambers of Commerce and the World Trade Center in West Palm Beach.
Additionally, Scripps Florida showcased its state-of-the-art facility by providing tours of
the Scripps Florida laboratories to visitors with both a business and scientific interest.
Scripps Florida participated and spearheaded over 120 business and community outreach
activities in fiscal 2007. See Appendix D, “Scripps Florida Outreach Activities” for a
detailed listing of the Business, Science and Community Outreach efforts.
Developing the Biotech Cluster Update on the 2006 Innovation Incentive Fund
The Innovation Incentive Fund enables Florida to attract world-class research and
development opportunities and/or innovative business projects that support the growth of
high-technology innovation clusters and high-wage jobs in Florida. Funding is matched
by investment of the local community. In last year’s Innovation Incentive Fund and as
mentioned in the 2006 SFFC annual report, the Torrey Pines Institute for Molecular
Science and the Burnham Institute received funding to expand operations to Florida.
Most recently, SRI International secured grants from the Fund. All three were approved
for funding in November 2006 and each recipient received its first grant in early 2007.
Burnham Institute for Medical Research
Site: Lake Nona, Orlando
Temporary Facilities: 14,000 square feet at the Florida Blood Center
Permanent Facilities: 175,000 square feet on 50 acres at the Lake Nona site in Orlando
Jobs in FL: 303 Average salary: $70,005 Money from State: $155.272 million
Local community partners that matched state funds: Orange County, City of
Orlando, University of Florida, University of Central Florida, Lake Nona Land Company,
LLC; also arranged for access to human tissue samples generated by Florida Hospital and
Orlando Regional Hospital
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Required Equipment Investment: $61 million
The Burnham Institute for Medical Research broke ground on its 175,000 square foot
permanent facility, located outside Orlando, Florida on Lake Nona, in October 2007.
Burnham’s goal is to build a 250-300 person operation over the next 7-10 years, staffed
primarily through recruiting new scientists. Funding for the expansion is supported by the
State of Florida, City of Orlando, Orange County, the Tavistock Group and generous
philanthropic support.
The Florida operation will focus on cancer, infectious/inflammatory diseases and
neurosciences/aging, supported by technology cores in pharmacology, in vitro and in
vivo toxicology, medicinal chemistry, chemical compound library screening and in vivo
imaging. Burnham also plans to launch an additional research program in diabetes and
obesity in Florida. The Burnham Institute for Medical Research features a technological
infrastructure that complements the work of the Institute in San Diego, so the integrated
organization will drive scientific discoveries more rapidly toward clinical proof of
concept.
Torrey Pines Institute for Molecular Science
Site: Port St. Lucie
Temporary Facilities: 15,000 square feet at the FAU/ Harbor Branch Oceanographic
Institute
Permanent Facilities: 107,000 square feet on 20 acres at the Tradition Community,
Port St. Lucie
Jobs in FL: 189 Average salary: $62,321
Money from State: $32 million ($24.728 million from Innovation Fund, $7.272 million
from Quick Action Closing Fund)
Local community partners that matched state funds ($71.5 m): City of Port St. Lucie,
St. Lucie County, Florida Atlantic University, Tradition Development, LLC.
Required Construction/Equipment Investment: $35 million
The Torrey Pines Institute for Molecular Studies ("TPIMS") is a bicoastal biomedical
institution, with over 100 people working at its La Jolla, California base. TPIMS-FL is
currently located in temporary laboratories and offices in the FAU / Harbor Branch
facility in Fort Pierce. TPIMS employs four principal investigators, five laboratory
technicians and four non-scientific personnel - two administrative assistants, a facilities
manager and a public affairs director - and anticipates over 200 employees in the next ten
years.
The scientists at the Torrey Pines Institute research new chemical methods for drug
discovery, seek to understand neuropathways to address pain modification, and use
computational chemistry to better understand interactions with receptors. The Institute's
scientific outreach seminars have resulted in signed material transfer agreements with
Florida Atlantic University, the University of Florida and the USDA in Fort Pierce.
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Scripps Florida Funding Corporation 15
Annual Report 2007
In addition to its research on drug discovery, TPIMS-FL enjoys participating in
community and educational outreach. Discussions with the School Board of St. Lucie
County are underway and an intern program is planned for summer 2008. TPIMS-FL
will be permanently housed in a 107,000 square foot green-certified facility in the Florida
Center for Innovation at Tradition in Port St. Lucie. This facility opens in December
2008 and Florida will become the Institute's headquarters in summer 2009.
SRI International
Site: St. Petersburg Temporary Facilities: at University of South Florida
Permanent Facilities: 30,000 to 35,000 square feet on the eastern edge of the Port of St.
Petersburg within the Bayboro area, a designated state Enterprise Zone, leased to SRI-
STP by the City of Petersburg. Phase II calls for an additional facility of 70,000
square feet.
Jobs in FL: 160 Average salary: $72,500 Money from State: $20 million
Local community partners that matched state funds: City of St. Petersburg, Pinellas
County, University of South Florida’s College of Marine Science and its Center for
Ocean Technology (COT), FSTED grant funds
Required Equipment Investment: $2 million
On November 30, 2006, SRI International, one of the world's leading independent
research and technology development organizations, announced it had selected St.
Petersburg, Florida as the site for a new marine technology research facility. Silicon
Valley-based SRI International is one of the world's leading independent research and
technology development organizations. In addition to conducting contract research and
development, SRI licenses its technologies, forms strategic partnerships and creates spin-
off companies. In October 2007, SRI International announced that it had licensed its first
Florida-based technology.
The new facility will be called SRI-St. Petersburg and aims to accelerate research and
development of technologies related to ocean science, the maritime industry and port
security. SRI's expansion into Florida is in collaboration with the University of South
Florida's College of Marine Science and its Center for Ocean Technology and is
supported by the City of St. Petersburg, Pinellas County and the State.
Florida’s Innovation Economy Legislation During 2007, Governor Crist and the Florida Legislature funded the following legislation
to enhance Florida’s biotechnology industry. This legislation, enacted in the spring 2007
legislative session, accelerates the growth of Florida’s Innovation Economy by
developing the biotechnology cluster and capitalizing on the success of Scripps Florida.
Governor Crist signed the following legislation:
• $250 million continued funding for the Florida Innovation Incentive Fund.
Consistent with the 2006 legislation, the local community will match the state
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Scripps Florida Funding Corporation 16
Annual Report 2007
investment. The Innovation Incentive Fund legislation included proviso language
for $80 million to be directed to the Institute for Human Genomics.
• $45 million continued funding for the Quick Action Closing Fund, enabling the
state to offer a cash incentive to companies considering Florida as the location for
their business. This fund helps Florida compete with other states and nations to
bring high-wage, professional jobs to Florida.
• $31 million in funding to create the Florida Capital Formation Act, which requires
Enterprise Florida, Inc., to facilitate the creation of the Florida Opportunity Fund.
The Opportunity Fund will increase availability of seed capital and early stage
venture equity capital for emerging companies in Florida which are creating new
businesses and jobs.
• $100 million (a $70 million increase in funding) for the Centers of Excellence
Program to recreate and enhance the Centers of Excellence program, allowing
state universities and their research partners to leverage public and private dollars
to establish research and commercialization centers that support emerging
technologies. The collaboration between industry and academia will help drive
inventions and innovations from the lab to the marketplace.
• $44.6 million to Florida Atlantic University to acquire the Harbor Branch
Oceanographic Institute as a research institute of the University.
Institute for Human Genomics
The University of Miami Miller School of Medicine established the Institute for Human
Genomics in January 2007 and it will receive $80 million in funding from the 2007
Innovation Incentive Fund. The Institute will explore the genetic influences on human
health and apply this knowledge to the practice of medicine through improved
diagnostics, treatments, and medications, thus translating the unprecedented scientific
advance of the “Human Genome Project” into information that can benefit patients
directly. The Institute is committed to collaborative pan-institutional initiatives, ensuring
that resources, skills, and ideas forthcoming from novel genetic and genomic approaches
will be made available to the entire medical community.
Expanding the Biotech Industry in Palm Beach County The Max Planck Society In September 2007, the Max Planck Society announced plans to expand its operation to
Palm Beach County and the Palm Beach County Commission voted to authorize the
negotiations to fund a grant agreement for approximately $87 million. The Max Planck
Society is a world-renowned basic biomedical research institute, based in Germany,
which employs approximately 23,400 people worldwide. The Society performs basic
research in the interest of the general public in the natural sciences, life sciences, social
sciences and the humanities. In particular, the Max Planck Society takes up new and
innovative research areas that universities are not in a position to accommodate or deal
with adequately. The Society has an innovative track record, which includes a
technology transfer arm that focuses on commercializing discoveries through spin-off
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Scripps Florida Funding Corporation 17
Annual Report 2007
businesses. Since 1990 the organization has successfully spun-off 76 companies. The
organization also has produced 16 Nobel Prize winners since 1948.
The Society’s plans for its Florida operations call for:
• A scientific focus on bio-imaging using the most advanced techniques for
visualization of microscopic molecular processes to achieve a deeper
understanding of the structure, dynamics and function of molecules and tissues in
order to tackle challenging problems in biology, bioengineering and medicine.
• An emphasis on translating discoveries from a molecular level to a patient-
oriented application.
• A substantial complimentary, collaborative relationship with Scripps Florida.
• Strong links to Florida Atlantic University to enhance its bioscience programs.
• Full engagement in the county’s K through 12 education system, with outreach to
all sectors of society.
FAU has offered six acres to Max Planck at its Jupiter campus in close proximity to
Scripps Florida. The Max Planck Society is currently in negotiation with Palm Beach
County and is awaiting approval of its request for a $93 million grant from the 2007
Innovation Incentive Fund. Alexandria Innovation Center Alexandria Real Estate Equities, the largest developer of lab space in the United States,
recently completed renovation of a 46,000 square feet building for incubator space
adjacent to the growing biotech cluster in Jupiter, Florida. The Alexandria Innovation
Center is a first-class scientific property, with wet lab suites and shared support services.
Interlocal Agreement In March 2006, five municipalities entered into an Interlocal Agreement with Palm Beach
County to protect the 8 million square feet of land surrounding Scripps Florida for the
growth of the biotech cluster. The municipalities - Palm Beach Gardens, Jupiter,
Mangonia Park, Lake Park and Riviera Beach – were required to initiate comprehensive
plan amendments creating Bioscience Research Protection Overlays in their
comprehensive plans to identify lands within the Overlay and protect these lands from
commercial or residential development. To date:
• Palm Beach County, the City of Palm Beach Gardens and the Town of Jupiter
have amended their Comprehensive Plans to incorporate the Bioscience Overlay.
• The Town of Mangonia Park, Town of Lake Park and City of Riviera Beach are
transmitting amendment packages to the Florida Department of Community
Affairs and should be completed by August 2008.
Additionally, the Agreement provided for the formation of an Advisory Board to make
recommendations regarding amendments to comprehensive uses on properties within the
municipal Overlays. However, since most of the municipalities have not adopted the
Overlay plan, the Advisory Board has no authority to consider matters brought before the
Board in those municipalities.
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Annual Report 2007
BioFlorida 2007 This year, BioFlorida celebrated the 10
th Anniversary of its bioscience conference. As in
previous years, Scripps Florida participated in the annual event. Dr. Richard Lerner
participated in the plenary panel session while scientists presented in scientific breakout
sessions. Nearly 500 attendees from every sector of the life sciences industry attended
this conference.
BIO 2007 In May 2007, Enterprise Florida, Inc., in partnership with several county economic
development corporations and Florida universities, participated in BIO 2007, the world’s
largest biotechnology conference. Scripps Florida again participated as a sponsor and
demonstrator at the Florida Pavilion, aside numerous other representatives from Florida.
This year’s conference was held in Boston and drew a record attendance of nearly 23,000
attendees from 64 different countries.
Conclusion Scripps Florida Funding Corporation is pleased to report another successful year of
operations for Scripps Florida. Scripps Florida continues to advance its scientific
discoveries, secure grants and awards from outside sources, collaborate with Florida
universities and colleges, and interact with businesses and the community through its
outreach activities – all well ahead of its contractual requirements.
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Scripps Florida Funding Corporation 19
Annual Report 2007
Scripps Florida Funding Corporation Fourth Annual Report
Itemized Report for the Year Ended September 30, 2007 INTRODUCTION
Florida Statute 288.955, referred to as the Enabling Statute, sets forth certain information
that is required to be included in the SFFC Annual Report. The information that follows
has been organized to correspond to the sections of the Enabling Statute that address
information to be included in the SFFC Annual Report. As not every section of the
Enabling Statute relates to the SFFC Annual Report, only the sections of the Enabling
Statute that apply are referenced herein. For convenience, the text of the Enabling Statue
that describes the information to be set forth in the SFFC Annual Report is set forth next
to each Enabling Statute section reference.
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Scripps Florida Funding Corporation 20
Annual Report 2007
Scripps Florida Funding Corporation Fourth Annual Report
Itemized Report for the Year Ended September 30, 2007 Florida Statute 288.955 Subsection (14) ANNUAL REPORT
By December 1 of each year, the corporation shall prepare a report of the activities and outcomes under this section for the preceding fiscal year. The report, at a minimum, must include:
Subsection (14) (a) A description of the activities of the corporation in managing
and enforcing the contract with the grantee.
Scripps Florida Funding Corporation Board of Directors Meetings Please note the Scripps Florida Funding Corporation web site:
http://www.flgov.com/scripps
Purpose: To oversee the disbursement of the State’s funds invested in Scripps Florida,
the Florida Legislature created the Scripps Florida Funding Corporation, hereto referred
to as SFFC, a nonprofit entity governed by a nine-member Board of Directors, and one
ex-officio member.
Membership: Of the nine-member Board of Directors, three Directors were appointed by
each of the Governor, the House Speaker, and the Senate President. Governor Bush’s
appointees are: Mr. David Gury, former President and CEO of Nabi Pharmaceuticals, of
Boca Raton; Mr. Andy Crawford, Chairman of Advanced Disposal Systems, of
Jacksonville, and Dr. Pamella Dana, Senior Strategic Advisor for Institute for Human &
Machine Cognition, of Destin who was appointed January 1, 2007 for a term ending on
November 13, 2008. Speaker Byrd’s appointees are: Mr. Ruben Jose King-Shaw, Jr.,
Chairman & CEO, Mansa Equity Partners, Inc., of Carlisle, Massachusetts; Dr. Joseph
Thomas, dentist, of Vero Beach; and Mr. Chris Sullivan, Chairman of Outback
Steakhouse, Inc. of Tampa. President King’s appointees are: Mr. Jim McCollum, former
Regional Director for Bell South, now retired, of Jacksonville; and Mr. Bill Foley, CEO
of Fidelity National Financial, of Jacksonville. President Lee, President King’s
successor, appointed Dr. Edward Gonzalez, dentist, of Valrico. Dr. Dale Brill, Director
of the Governor’s Office of Tourism, Trade, and Economic Development (“OTTED”), is
an ex-officio member.
Meetings and activities: From October 1, 2006 through September 30, 2007, the SFFC
Board of Directors (“BOD”) held two teleconference meetings and one in-person
meeting. On November 28, 2006, the Board elected a new chairman and vice-chair,
approved the revised Scripps Florida Business Plan and approved the SFFC Third Annual
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Annual Report 2007
Report, authorizing the transmission of the report to the Governor, Speaker of the House
and the President of the Senate on December 1, 2006. Representatives from the offices
which contributed to the Annual Report were also on the call. At the January 22, 2007
meeting, Chairman Sullivan reorganized the committee structure of the SFFC BOD and
the BOD agreed to the insurance for the Board and to the 2007 SFFC Budget. On March
9, 2007, the BOD held its annual grant request meeting at the Jupiter campus of Florida
Atlantic University, adjacent to the Scripps Florida campus. This meeting involved the
annual grant request and was held in conjunction with the dedication of the Scripps
Florida campus. The SFFC Board was joined by representatives from TSRI – Mr. Tom
Northrup, Ms. Donna Weston, Ms. Carol Licko - and Scripps Florida – Mr. Harry Orf.
After an Audit Committee meeting, the Board attended the dedication ceremony with
Governor Crist, former Governor Bush and other dignitaries, and witnessed by 400
Scripps Florida employees and guests. The Board reconvened at the FAU facility to hold
its BOD meeting. The agenda included an update from the Audit Committee and the
annual grant request. In order to prepare the Board for the annual grant request, Ms.
Deutsch, SFFC counsel, reviewed the six requirements that Scripps had to meet for the
grant request. Those requirements are: the grant request form, receipt of TSRI and
Scripps Florida annual financial statements, the scientific report, the update to the annual
Report, the legal opinion and the satisfaction of disbursement conditions. She stated that
all items were properly received and the only exception to that was the employee issue
addressed in the compliance report, which Mr. Crawford explained had been discussed in
the Audit Committee meeting and found not to be material. After discussion, the 2006
annual grant request was approved unanimously.
SFFC Committee Meetings
Investment Committee
Purpose: The Investment Committee receives and reviews quarterly investment reports
from the State Board of Administration (SBA) to ensure that SFFC’s investments are
consistent with the objectives established in the Trust Agreement and that SFFC is able to
make the disbursements anticipated in the Operating and Funding Agreement between
SFFC and TSRI.
Membership: Mr. Bill Foley is the Chairman of the Investment Committee and Dr. Ed
Gonzalez and Mr. Jim McCollum are Committee Members. Mr. Michael Lombardi from
the SBA participates in the Committee meetings.
Meetings and activities: The Investment Committee held four meetings at which they
primarily reviewed the quarterly reports from the SBA. At the October 4, 2006 meeting,
the Investment Committee reviewed the June 30, 2006 reports from the SBA and
accepted the revised disbursement schedule, with Mr. Lombardi and Ms. Misselhorn
presenting the new schedule for the quarterly disbursements due to the revisions in the
Scripps Florida Business Plan. Ms. Misselhorn explained that Scripps had reviewed and
agreed to this new schedule and the Committee agreed to adopt the new disbursement
schedule, pending final approval of the revised Business Plan. At the June 21, 2007
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Annual Report 2007
meeting, Mr. Lombardi reviewed the December 31, 2006 and March 31, 2007 SBA
reports for the Investment Committee and Committee Chairman Crawford remarked that
these were ‘very good reports and the investment schedule was well structured.’ The
Committee agreed that two meetings per year would be sufficient to continue to monitor
the investment accounts.
Audit Committee
Purpose: The Audit Committee reviews financial information and monitors the financial
condition of TSRI and Scripps Florida. The Audit Committee also provides oversight for
the annual audit of SFFC and compliance monitoring of TSRI and Scripps Florida with
the terms of the Operating and Funding Agreement. The Audit Committee provides
direction on the scope of the audit engagements and reviews any finding or
recommendations related to the audits. The Audit Committee, in turn, reports its
recommendations on the reports to the full Board.
The Scripps Florida Funding Corporation receives and the Audit Committee reviews the
following reports from TSRI and Scripps Florida:
• TSRI and Scripps Florida unaudited quarterly financial statements
• TSRI and Scripps Florida audited annual financial reports
• TSRI and Scripps Florida annual budgets
• Scripps Florida Annual Report
• Scripps Florida Annual Scientific Report
There are three types of annual audit reports that are received and reviewed by the Audit
Committee as follows:
1. Scripps Florida and TSRI provide three annual audit reports to SFFC:
a) Audited financial statements of TSRI, including the operations of Scripps
Florida.
b) Audited financial statements of Scripps Florida as a separate division,
including a report on internal control and compliance in accordance with
Government Auditing Standards.
c) A Federal Single Audit of TSRI in accordance with OMB Circular A-133.
The audits are prepared by Deloitte and Touche (“D&T”), the independent
auditors for TSRI. SFFC’s independent auditor has been granted access to the
D&T workpapers in order to assess the application of generally accepted
accounting principles and the significant assumptions made by TSRI
management in the preparation of its financial statements.
2. SFFC receives two annual audit reports completed by an independent auditor
contracted by the SFFC:
a) Audited financial statements of SFFC, including a report on internal
controls and compliance in accordance with Government Auditing
Standards.
b) A Federal Single Audit of SFFC in accordance with OMB Circular A-133.
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Annual Report 2007
3. A contractual monitoring and compliance audit of the Operating and Funding
Agreement between TSRI and SFFC (“contractual monitoring and compliance
audit”) to address the Monitoring Checklist (Exhibit A-1 to the Funding and
Program Agreement between OTTED and SFFC). The contractual monitoring
and compliance audit is completed by an independent auditor contracted by the
SFFC who verifies many of the items covered in this Annual Report, including,
but not limited to:
a) the number of jobs created
b) the average salaries and their consistency with the approved Business Plan
c) designation of a person to assist in collaborative efforts with OTTED and
compliance with OTTED’s requests for cooperation
d) purchase of equipment is consistent with the approved budget
e) achievement of collaborative efforts with Florida universities
The independent auditor contracted by the SFFC also prepares the annual not-for-profit
organization tax return (Form 990) for SFFC, which is reviewed by the Audit Committee
prior to submission to the Internal Revenue Service.
Membership: Mr. Andy Crawford is the Chairman of the Audit Committee and Dr.
Joesph Thomas and Dr. Pamella Dana are Committee Members. Other participants in the
Audit Committee meetings include representatives from TSRI’s auditors, Deloitte and
Touche, SFFC’s auditor, Mr. Scott Porter from Caler, Donten, Levine, Druker, Porter &
Veil, PA, and TSRI’s Chief Financial Officer, Ms. Donna Weston.
Meetings and activities: From October 1, 2006 through September 30, 2007, the Audit
Committee participated in four meetings to review, amend, discuss and approve several
financial reports provided by TSRI, and the auditing and compliance matters of SFFC.
At the October 10, 2006 meeting, the Audit Committee accepted the Scripps Florida 2007
Budget and reviewed the June 30, 2006 unaudited financial statements of TSRI and
Scripps Florida. At the February 2, 2007 meeting, Mr. Porter reviewed the SFFC Tax
Form 990 and the revised terms of the engagement letter for the compliance audit with
the committee. At the March 9, 2007 meeting, Ms. Weston provided an overview of the
TSRI and Scripps Florida Deloitte and Touche audit reports for the year ended September
30, 2006 and the December 31, 2006 unaudited financials. Since Mr. Porter was still
reviewing the workpapers, the Committee agreed to suggest to the Board that the
approval of the grant would be contingent upon the complete review of these workpapers,
with approval from the Chairman and legal counsel as well. At this meeting, the annual
compliance report of how Scripps Florida is meeting the performance expectations was
reviewed and accepted for presentation to the full BOD, with discussion about a
discrepancy which the Audit Committee found to be not material. Also, Mr. Porter
presented the SFFC complete single audit draft. At the June 25, 2007 meeting,
Committee Chair Crawford followed up on business from the previous meeting, stating
that Mr. Porter completed his review of the work papers and found everything to be in
order. He also finalized the compliance report and the Committee accepted it. Ms.
Weston explained the supplemental schedule provided for the September 30, 2006 and
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Annual Report 2007
December 31, 2006 unaudited financials, and then presented information to the
Committee on the March 31, 2007 unaudited financials from TSRI and Scripps Florida.
Reports Committee
Purpose: The predominant purpose of the Reports Committee is to review and approve
the Annual Report before it is reviewed and approved by the SFFC Board of Directors.
Membership: Chairman Sullivan is the acting Chair of the Reports Committee. Mr.
King-Shaw and Mr. Gury are Committee Members.
Meetings and Activities: The Reports Committee received drafts of the annual report
over the course of October and November 2006 in order to review the content of the
annual report before it was submitted to the full Board of Directors.
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Scripps Florida Funding Corporation 25
Annual Report 2007
Subsection (14) (b) An accounting of the amount of funds disbursed during the preceding fiscal year to the grantee. Disbursement Date Principal Interest TOTAL December 15, 2006 $ 2,910,000.00 $ 261,385.39 $ 3,171,385.39 March 15, 2007 $ 8,939,750.00 $ 697,270.23 $ 9,637,020.23 June 15, 2007 $ 8,939,750.00 $ 991,969.39 $ 9,931,719.39 September 17, 2007 $ 8,939,750.00 $ 1,093,541.15 $10,033,291.15
TOTAL $29,729,250.00 $3,044,166.16 $32,773,416.16 This disbursement schedule became effective in November 2006 when the SFFC
accepted the revised business plan of Scripps Florida.
Subsection (14) (c) An accounting of the expenditures by the grantee during the
fiscal year of funds disbursed under this section. Report of SFFC Grant Disbursements from October 1, 2006 to September 30, 2007
Category Amount
Salaries & Benefits $9,674,131
Supplies $5,642,651
Scientific Equipment $2,742,332
External Affairs & Other Program Support $986,660
Project Commencement, Facilities,
Administration and Capital Expenditures
$9,492,140
Total $28,537,914
This schedule reflects cash expenditures charged to the grant from the State of Florida
from October 1, 2006 through September 30, 2007. The expense categories set forth
above reflect those used by Scripps to report grant activity to grantors. This schedule
excludes: unpaid commitments; unspent grant funds received of $35,258,500 (including
interest income); and expenditures funded by other sources.
Subsection (14)(d) Information on the number and salary level of jobs created by the grantee, including the number and salary level of jobs created for residents of this state.
Report of Scripps Florida Employees Count
Position Employee Count
As of September 30, 2007 Year 4 Target Faculty 20 > 15
Scientific Staff *
165 > 124
Administration **
38 > 30
Current Total 223 Job Creations Target 225
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Scripps Florida Funding Corporation 26
Annual Report 2007
* Scientific Staff includes non-tenure track scientists, research associates, lab technicians,
Scripps paid graduate students and interns.
**
Administration includes all other support personnel.
The job creations target number is to be measured on December 31, 2007, the end of the
fourth employee hire year. SFFC may allow a downward deviation of 25% as
satisfaction of the job creation deliverable. Scripps Florida management anticipates that
the target head count will be met by December 31, 2007.
Scripps Florida hired 73 employees between October 1, 2006 and September 30, 2007.
Of those new hires, 29 were Florida residents and 27 were Palm Beach County residents.
Category Required Salary Range (as stated in
Business Plan)
Hired in fiscal 2007
Current Salary Range
Professors $138,000 to $330,000 + 2 $142,917 +
Associate Professors $84,000 to $177,000 1 $86,923 to $223,288
Assistant Professors $72,000 to $129,000 1 $74,963 to $132,371
Research Faculty $72,000 to $265,000 2 $80,000 to $270,000
Staff Scientists $54,000 to $113,000 4 $56,326 to $116,397
Research Associates/
Science Support
$34,000 to $55,000 48 $37,000 + *
Administration $48,600 **
15 $50,544
TOTAL 73
* Research Associates Only
** Represents the average expected salary for this employee category, rather than the
range that would result in combining all Administrative position salaries. The various job
classifications and range of salaries is broad. In this instance, an expected average salary,
rather than a range, is a better representation.
The base salary of all persons employed in a particular category falls within the range for
that category. These ranges are increased each year to reflect the change in the CPI for
that annual period. Certain employees of Scripps Florida may receive additional
compensation for assuming administrative responsibilities beyond their scientific duties.
For example, a faculty member who also serves as an Associate Dean of the Graduate
School will receive additional compensation for that service. The ranges set forth above
do not incorporate such additional compensation.
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Scripps Florida Funding Corporation 27
Annual Report 2007
Category Required Salary Range (as stated in
Business Plan)
Hired in fiscal 2007
Actual Salary in fiscal 2007
Florida Residents
Palm Beach Co. Residents
Professors $138,000 to $330,000 + 2 $208,000 to $265,000 0 0
Associate Professors $84,000 to $177,000 1 $160,014
0 0
Assistant Professors $72,000 to $129,000 1 $95,722 0 0
Research Faculty $72,000 to $265,000 2 $81,162 to $84,178 0 0
Staff Scientists $54,000 to $113,000 4 $55,016 to $72,010 0 0
Research Associates/
Science Support
$34,000 to $55,000 48 $35,984 to $78,000 * 16 15
Administration $48,600 **
15 $50,544 13 12
TOTAL 73 29 27
* This is a combination of full-time, regular research associates and various science
support positions. The minimum Research Associate annualized salary is $37,000.
** Represents the average expected salary for this employee category, rather than the
range that would result in combining all Administrative position salaries.
Subsection (14) (e) Information on the amount and nature of economic activity generated through the activities of the grantee.
See Appendix A, “The Economic Impact of Scripps Florida on Florida’s Economy,”
prepared by Enterprise Florida for SFFC in November 2007.
Subsection (14) (f) An assessment of factors affecting the progress toward achieving the projected biotech industry cluster associated with the grantee’s operations, as projected by economists on behalf of the Executive Office of the Governor.
See Appendix B, “An Assessment of Factors Affecting the Progress Toward Achieving
the Projected Biotech Industry Cluster,” prepared through information provided by Palm
Beach County’s Business Development Board, Workforce Alliance, BioFlorida and
Enterprise Florida, Inc.
Subsection (14) (g) A compliance and financial audit of the accounts and records of the corporation at the end of the preceding fiscal year conducted by an independent certified public accountant in accordance with the rules of the Auditor General.
See Appendix C, The “Audited Financial Statements and Supplementary Financial
Information” for SFFC for the period ended September 30, 2007.
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Subsection (14) (h) A description of the status of performance expectations under subsection (9) and the disbursement conditions under subsection (10).
Subsection (9) PERFORMANCE EXPECTATIONS
Subsection (9) (a) The number and dollar value of research grants obtained from
the Federal Government or sources other than this state. Since the establishment of Scripps Florida, faculty and staff have been awarded 41
research grants from sources other than SFFC. The total value of those grants is
$30,720,790. Nine (9) of the 41 grants were awarded between October 1, 2006 and
September 30, 2007. The total value of those nine awards is about $7,550,893.
Subsection (9) (b) The percentage of total research dollars received by TSRI from sources other than this state which is used to conduct research activities by the grantee in this state.
For fiscal 2007, the percent of research funding from sources other than SFFC is 20.2%
and these amounts were used for this purpose.
Subsection (9) (c) The number or value of patents obtained by the grantee.
Since its inception, 63 patent applications have been filed by Scripps Florida. Thirteen
(13) patent applications naming a Scripps Florida scientist as an inventor or co-inventor
were filed between October 1, 2006 and September 30, 2007. All of the applications are
under review by the U.S. Patent and Trademark Office. Since none of the applications
have issued as a patent, there is no value yet assigned to these applications.
Subsection (9) (d) The number or value of licensing agreements executed by the grantee.
Eight patent applications were licensed during fiscal 2007. No value has been assigned
to those licenses and no revenue has been generated from the licenses. The licensing
agreement defines when and how revenues will arrive. Those financial terms are
confidential due to the unpredictability of the industry.
Subsection (9) (e) The extent to which research conducted by the grantee results in commercial applications.
Because of the early stage of the technology being developed at Scripps Florida and the
time delay attendant to further development, no commercial applications and revenue
have emerged to date.
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Subsection (9)(f) The number of collaborative agreements reached and maintained with colleges and universities in this state and with research institutions in this state, including agreements that foster participation in research opportunities by public and private colleges and universities and research institutions in this state with significant minority populations, including historically black colleges and universities.
The Scripps Research Institute has developed a template, the Joint Cooperation
Agreement (“JCA”), to encourage and support research collaborations with Florida
institutions. Provisions are included to make it easier to collaborate on filing patents for
jointly developed technologies and to share revenues from commercialized innovations.
By executing these agreements in advance, it streamlines the scientific collaboration
process between Florida organizations and Scripps Florida as they work together on
biomedical research. To date, six Florida institutions have executed this formal
agreement with TSRI: University of Florida; Florida Atlantic University; University of
Central Florida; University of Miami; Florida State University; and Nova Southeastern
University.
The JCA with Nova Southeastern University was executed during fiscal 2007.
Currently, there are 32 scientific collaborative relationships between Scripps Florida
scientists and their colleagues at colleges and universities within the State of Florida. See
Appendix D, “Scripps Florida Outreach Activities” for a detailed listing of these
Collaborations.
Subsection (9) (g) The number of collaborative partnerships established and maintained with businesses in this state.
Scripps Florida has established collaborative relationships with three Florida based
businesses. No new formal collaborative relationships were established in fiscal 2007.
The existing relationships with The Jupiter Medical Center, Dyadic International, Inc.,
and IBM are ongoing. Until publication or filing of a patent application, disclosure of the
results or nature of the collaborative agreement is forbidden because public disclosure
can potentially destroy the patentability.
The Jupiter Medical Center
The Jupiter Medical Center agreed to analyze select specimens for Dr. Layton Harris
Smith, Director of Pharmacology at Scripps Florida’s Department of Drug Discovery to
further his biomedical research.
Dyadic International, Inc.
In March 2006, a collaborative effort between scientists at Scripps Florida and Dyadic
International, Inc. (AMEX: DIL), a Jupiter-based biotechnology company, was
established to provide a complete annotation of the genome of Dyadic's proprietary
fungal organism, Chrysosporium lucknowense ("C1"). The knowledge gained from this
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effort is expected to facilitate further development of the C1 Host Technology as a robust
platform for the discovery, development and production of various materials for medical
and industrial applications.
IBM
An ongoing initiative established in February 2006, Project Checkmate is the
collaboration of TSRI and IBM to conduct advanced research on pandemic viruses
leveraging the industry-leading talent and technology from both organizations. This
initiative capitalizes on TSRI’s world-class research in the areas of biochemical modeling
and drug discovery and IBM's expertise in computational biology bio-patterning and
supercomputing. The joint research team exploits the use of IBM's Blue Gene
supercomputer, the world's fastest supercomputer technology, and have access to a state-
of-the-art biomedical research facility, Scripps Florida.
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Subsection (9) (h) The total amount of funding received by the grantee from sources other than the State of Florida.
Since inception, Scripps Florida has been awarded 41 grants totaling approximately $30.7
million from state and federal agencies including the NIH, foundations, pharmaceutical
companies and other grantors. During fiscal 2007, Scripps Florida received the following
grants:
GRANT AWARDS ($30,720,790 since inception) $ 7,550,893
OTHER REVENUE SOURCES * $ 9,291,151
CONTRIBUTIONS AT NET PRESENT VALUE ** $ 692,183
PALM BEACH COUNTY ($84,905,632 since inception) *** $ 59,215,156
TOTAL $ 76,749,383
* OTHER REVENUE SOURCES:
Palm Beach County – use of land and T-2 (no cash) $ 1,208,957
Investment Income on Florida funds 5,054,635
Pfizer 3,027,559
Total $ 9,291,151
** CONTRIBUTIONS ORIGINALLY REPORTED AS OF JUNE 30, 2007
Contributions above 692,183
Net Change ($ 447,817)
The decline results from the write-off of a pledge that is contingent on the
completion of construction at the permanent site. Similar to other revenue
related to the construction of the permanent site, this pledge will be
recognized as income, when occupancy appears certain, most likely during
the fiscal year ended September 30, 2008.
Contributions include gifts not dedicated to a specific type of research;
grants typically have a dedicated area of research or are awarded to a
specific scientist.
*** COUNTY FUNDS EXPENDED TO DATE BY FISCAL YEAR
2004 $ 1,713,494
2005 11,419,527
2006 12,557,455
2007 59,215,156
Total $ 84,905,632
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YEAR-TO-YEAR COMPARISON OF NON-SFFC FUNDING TO SCRIPPS FLORIDA
Grant Funds Awarded Since Inception Grant Funds Expended
2005 $ 12,058,237 * 2005 $ 2,549,086
2006 $ 6,533,283 2006 $ 3,007,000
2007 $ 12,129,270 2007 $ 7,550,893
Total Grants Awarded $ 30,720,790 Total Awards Expended $ 13,106,979
* The higher amount of grants awarded in 2005 are a result of hiring several scientists
who brought grant support with them and the existing awards were included in the 2005
number. The decline in 2006 is due to the fact that Scripps did not hire as many people
with existing grants, although some of the younger faculty members were successful in
obtaining their first grants. The 2007 grants awarded amount is more robust than
expected because it includes more than $4 million in funding from the Pfizer agreement.
These awards are disbursed over as many as five years, so many of the scientists will not
seek new funding for some time. Scripps anticipates that the amount of grants awarded
in 2008 will be in the range of about $10 million to $12 million.
Subsection (9) (i) The number or value of spin-off businesses created in this state as a result of commercialization of the research of the grantee.
In May 2007, Scripps Florida’s announced its first private drug-discovery start-up,
Xcovery. Based in West Palm Beach, the company develops new therapeutic products
addressing indications in oncology and inflammation. Scripps Florida scientist, Dr. Chris
Liang, invented the technology at Scripps Florida.
Subsection (9) (j) The number or value of businesses recruited to this state by the grantee.
Scripps and the State of Florida have engaged in discussions with several companies who
desire to establish a presence in Florida. Earlier this year, the Burnham Institute for
Medical Research, the Torrey Pines Institute for Molecular Studies and SRI International
received funding from the Innovation Incentive Fund and are actively expanding their
operations in Florida. In September 2007, the Max Plank Society announced its intentions
to establish a branch in Palm Beach County. It is negotiating contracts with the State
and local governments and will seek $190 million in grants from the Innovation Incentive
Fund, with matching local funds. Additionally, the cluster is organically growing with
numerous smaller, science-based companies and spin-off businesses which are
establishing operations in the developing biotech cluster area.
Subsection (9)(k) The establishment and implementation of policies to promote supplier diversity using the guidelines developed by the Office of Supplier Diversity under s. 287.09451 and to comply with
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the ordinances, enacted by the County and which are applicable to this biomedical research institution and campus located in this state.
It is the policy of Scripps Florida to offer diverse businesses an opportunity to compete
on an equal basis with all other vendors. The Scripps Florida policy defines a diverse
business as a Minority Business Enterprise, Woman Business Enterprise, Small Business
Enterprise, or Veteran Business Enterprise. Scripps Florida searches for qualified
vendors, beginning in Palm Beach County and expanding out to the State of Florida and
beyond. In an effort to provide local businesses with valuable information about
upcoming opportunities at Scripps Florida, a collaborative Scripps Florida/ FAU vendor
show was hosted on the FAU John D. McArthur Campus on October 25, 2006. Over 300
local business owners met with key decision makers from Scripps Florida to discuss
potential business partnerships and supplier qualifications.
In addition to the Scripps Florida/ FAU vendor show, Scripps Florida participated in
numerous supplier shows throughout Florida to identify diverse businesses that can
provide goods and services to Scripps Florida. Participation in these shows has resulted
in partnerships with local companies that provide furniture, pipette calibrations,
refrigeration services, temporary staffing, building maintenance services, printer supplies
and more.
Subsection (9) (l) The designation by the grantee of a representative to coordinate with the Office of Supplier Diversity.
Mr. Audric Dodds is the designated Scripps Florida representative who coordinates with
the Office of Supplier Diversity. Mr. Dodds currently sits on the board of directors of the
Women’s Business Development Center and was appointed by the State of Florida Office
of Supplier Diversity to the State of Florida Small Business Advisory Committee.
Subsection (9) (m) The establishment and implementation of a program to conduct workforce recruitment activities at public and private colleges and universities and community colleges in this state which request the participation of the grantee.
Ms. Hollie Alkema, Scripps Florida’s Human Resource Analyst and Recruiter,
participated in 13 Career Fair and Expositions at institutions throughout the state during
fiscal 2007. See Appendix D, “Scripps Florida Outreach Activities” for a detailed listing
of the Workforce Recruitment efforts.
Subsection (10) DISBURSEMENT CONDITIONS
Subsection (10)(a) Demonstrate creation of jobs and report on the average salaries paid.
See reply to Subsection (14) (d).
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Subsection (10)(b) Beginning 18 months after the grantee’s occupancy of its permanent facility, the grantee shall annually obtain $100,000 of non-state funding for each full-time equivalent tenured-track faculty member employed at the Florida facility.
Not applicable until occupancy of the permanent facility.
Subsection (10) (c) No later than 3 years after the grantee’s occupancy of its
permanent facility, the grantee shall apply to the relevant accrediting agency for accreditation of its Florida graduate program.
Scripps is not expected to occupy its permanent facility until early 2009.
Subsection (10) (d) The grantee shall purchase equipment for its Florida facility as scheduled in its contract with the corporation.
Approximately $2,742,332 of equipment – acquired with State grant funds – was
purchased between October 1, 2006 and September 30, 2007. Additionally, $259,617 of
equipment was purchased with non-State funds for the twelve months ending September
30, 2007. The revised Schedule 4.4 (c) indicates that an estimated $1 million was
scheduled for Year 4 equipment purchases.
Subsection (10)(e) No later than 18 months after occupying its permanent facility, the grantee shall establish a program for qualified graduate students from Florida universities permitting them access to the facility for doctoral, thesis-related research.
Although Scripps is not scheduled to commence operations in its permanent facility until
early 2009, Scripps Florida had nine graduate students enrolled in its Kellogg School of
Science and Technology for the 2006-2007 school year. In May 2007, the first Ph.D.
student graduated. Two additional graduate students began the program in August 2007.
The Scripps Florida graduate admissions committee reviews all applications submitted by
Florida residents, or students from Florida colleges and universities, who submit
applications to TSRI’s La Jolla campus, but who did not specifically apply to Scripps
Florida. Several offers have been made to qualified individuals from this pool in each of
the past two years. Currently, there is one Florida graduate in the Ph.D. program, four
Florida undergraduates in research internships, and ten Florida post doctoral fellows
(research associates) at the Scripps Florida facility. As the faculty ranks at Scripps
Florida grow over the next several years, additional efforts will be made to recruit highly
qualified Florida students to the Scripps Florida Ph. D. program
Subsection (10) (f) No later than 18 months after occupancy of the permanent
facility, the grantee shall establish a summer internship for high school students.
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In the summer of 2007, nine Palm Beach County students participated in the Scripps
Florida’s High School Summer Internship Program, an increase from seven students a
year ago. The internship exposes students to a variety of contemporary issues in basic
biomedical research, providing hands-on laboratory experience, thus motivating and
preparing students for continuing education in the sciences. Internships were awarded on
a competitive basis to students beginning their junior or senior years in a Palm Beach
County high school in the fall 2007. Students applied through an online form and
applicants with a minimum grade point average of 3.0 who were at least 16 years of age
submitted letters of recommendations, transcripts, resumes and other ancillary material.
Special emphasis was placed on identifying and recruiting students who are
underrepresented in the sciences. Students were given a gross compensation of $8.00 per
hour for the six-week summer program. The internship program began in the summer of
2005. See Appendix D, “Scripps Florida Outreach Activities” for a detailed listing of
Student Interns for summer 2007.
Subsection (10) (g) No later than 3 years after occupancy of the permanent facility, the grantee shall establish a research program for middle and high school teachers.
In the summer of 2007, three Palm Beach County teachers participated in the Summer
Research Program for Middle and High School Teachers at Scripps Florida. The
program commenced in the summer of 2005. The research program exposes teachers to
current laboratory techniques and procedures, provides information on a variety of
contemporary issues in basic biomedical research, creates ties and linkages to working
scientists who can assist them in curriculum development and creates opportunities for
teachers to share information and knowledge with their peers. The program emphasizes
the scientific process, research planning, bench experience, experimental design, data
analysis and interaction with laboratory personnel. As an adjunct to their day-to-day
responsibilities, participants are required to attend specially-designed seminars
throughout the course of the summer. For the summer 2007 program, the application
procedure was similar to the high school summer internship program and teachers were
given a gross compensation of $20.00 per hour for the six-week summer program. See
Appendix D, “Scripps Florida Outreach Activities” for a detailed listing of the Teacher
Interns for summer 2007.
Subsection (10) (h) No later than 18 months after occupancy of the permanent
facility, the grantee shall establish a program for adjunct professors.
Many of the current Scripps Florida faculty have received adjunct faculty appointments
with the University of Florida, University of Miami and/ or Florida Atlantic University.
Such adjunct appointments are intended to provide a mechanism for graduate students
enrolled in Florida research universities to collaborate with, to be co-mentored by, and to
perform research in the laboratories of a Scripps Florida faculty member. One FAU
student is currently working with a Scripps Faculty member according to this plan.
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A mechanism has been established for faculty members at Florida institutions who have
established collaborative research programs with Scripps Florida faculty to be appointed
to an Adjunct Professor position. The process is initiated by a Scripps Florida faculty
member who submits a nomination to his/her department chair. If the chair concurs, the
chair submits the nomination to the Office of the President for review and approval. One
such adjunct appointment—Dr. Greg Fields of Florida Atlantic University—has already
been established.
Subsection (10) (i) No later than 6 months after commissioning it high throughput
technology, the grantee shall establish a program to allow open access for qualified science projects.
In 2007, Dr. Smith at the Burnham Institute for Medical Research and Dr. Teplitski at the
University of Florida began using the “Access to Technologies” program at Scripps
Florida. Launched in 2006, the program continues to invite scientists from Florida
universities and other academic research institutions to use state-of-the-art screening
technologies at Scripps Florida's facilities in Jupiter for qualifying projects. Access to
Scripps Florida's High Throughput Screening (“HTS”) operation, similar to that used
widely by the pharmaceutical industry, speeds up the process of discovering new drugs to
treat a variety of human illnesses. The technology, which is one of five in the country, is
primarily for users within the State of Florida, however, Scripps Florida scientists
collaborate with researchers at universities and institutes across the country.
Subsection (10) (j) Beginning June 2004, the grantee shall commence collaborative
efforts with Florida public and private colleges and universities, and shall continue cooperative collaboration through the term of the agreement.
See the reply to Subsection (9) (f). Subsection (10) (k) Beginning 18 months after the grantee occupies the permanent
facility, the grantee shall establish an annual seminar series featuring a review of the science work done by the grantee and its collaborators at the Florida facility.
Scripps Florida continues to host two seminar series, which were established during fiscal
year 2005. The Scripps Florida Collaborative Seminar Series is a monthly series of
lectures featuring prominent Florida-based speakers from the academic, biotechnology or
pharmaceutical community. The series serves as a major foundation for creating
knowledge and technology-sharing opportunities, team building and collaborations
among biomedical researchers at Scripps Florida and other Florida research and academic
institutions and companies. The Collaborative Seminar presentations focus on topics
within the broad fields of biomedical science, advanced technologies applied to
biomedical research and drug discovery. The sessions are open to interested professionals
within the Scripps Florida and Florida scientific communities. The public lecture series,
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“Frontiers in Science”, also presents information within the broad fields of biomedical
science. See Appendix D, “Scripps Florida Outreach Activities” for a detailed listing of
the Seminar Series.
Subsection (10) (l) Beginning June 2004, the grantee shall commence
collaboration efforts with the Office of Tourism, Trade, and Economic Development by complying with reasonable requests for cooperation in economic development efforts in the biomed/biotech industry. No later than July 2004, the grantee shall designate a person who shall be charged with assisting in these collaborative efforts.
Scripps Florida has designated Mr. Douglas Bingham as their designee to assist OTTED
regarding collaborative economic development efforts between Scripps and OTTED.
Scripps has worked, directly and indirectly, with OTTED to foster biotechnology
economic development growth in Florida.
In fiscal 2007, Scripps Florida hosted various groups of dignitaries for familiarization
tours, in conjunction with the World Trade Center in West Palm Beach and other
economic development groups. Scripps Florida showcased its state-of-the-are facility to
representative from the World Trade Center in Germany in September 2007; to the
Minister of Health for the Republic of Ghana in July 2007; and to Consuls of the
Netherlands in March 2007.
Scripps Florida continued to connect with many business and community organizations
during fiscal 2007 by participating in meetings facilitated by local business and
government agencies, such as the Palm Beach County Business Development Board and
Chambers of Commerce. See Appendix D, “Scripps Florida Outreach Activities” for a
detailed listing of the Business, Science and Community Outreach activities by Scripps
Florida.