Download - Studies Relevant to Water Fluoridation
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8/10/2019 Studies Relevant to Water Fluoridation
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Studies Relevant to Water Fluoridation
and Considered For Inclusion
These studies have met the relevance criteria for the review. These studies will be
assessed to see whether or not they meet the full inclusion criteria for positive or
negative effects, and ultimately be included in the review.
1. Notes on the results of the studies of 5 year old children conducted in the West
idland since 1!"5. .#. ortality in fluoride and non$fluoride areas. %pringfield& 'llinois (epartment of )ublic
*ealth, %pringfield, The +ureau, 1!5#.
. (-NT/ effects of water fluoridation. %eventh report on the +rantford 0luoridation
aries %tudy.Med Serv J Canada1!23412&5!3$23.6. -ditorial& 0luoride to7icity.Lancet1!4#8"69&""!$!3.
5. :eview of the National )reventive (entistry (emonstration )rogram.Am J Public
Health1!"242869&66$6.
2. 0luorides and oral health. :eport of a W*; -7pert ommittee on ;ral *ealth %tatusand 0luoride
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urico$%an 0ernando. Odontologica Chilena1!5!461&1#$1#".
#3. nand (, +agga ;, ullic@ B. -ndemic fluorosis and dental decay $ preliminary
study.)ndian Journal Medical Re"earch1!2645#819&11$1#.#1. nand CD, :oberts CT. hronic 0luorine )oisoning in an a :eview of /iterature in
-nglish 1!62$1!"! and 'ndications 0or :esearch.$iomed Pharmacother1!!34668"9&61$
6#3.##. ndo T. ?omparative study of the prevalence of dental caries in permanent teeth of
school children living in regions with high and low fluoridesA.Rev *ac Odontol Sao
Paulo1!5418#9$.#. ngelillo '0, Torre ', Nobile =, Billari ). aries and fluorosis prevalence in
communities with different concentrations of fluoride in the water. Carie" Re"earch
1!!!48#9&116$1##.
#6. non. (ental 0luorosis and 0luoridation.*luoride1!"541"89&11$16.#5. anon. 0luoride& still a good public health value.Pharm# Time"1!!34528Cul9&135$13.
#2. nonymous. 0luorides 8inorganic, used in drin@ing water9 8=roup 9.)ARC
Monograph" on the evaluation o% the carcinogenic ri"+ o% chemical" to human"1!!".
#. nsell /. 0luoridation and the rheumatic diseases& a comparison of Watfird and/eigh.Ann#rheum#!i"1!254#5&2$5.
#". pperly 0. -ndemic goiter, dental caries and drin@ing water. Virginia M# Month1!524"8Can9.
#!. rcieri :r, arvalho d/, =onalves /r=e, lmeida *d, )ereira /, ;liveira
-d. -studo comparativo da prevalncia da c rie dent ria apos 13 8deE9 anos de adiFo defluor nas guas de abastecimento publico de
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findings after three years of water fluoridation.Am# J# Public Health1!534638Cune9&12$
#6.
61. st (, 0inn %, hase *. Newburgh$Dingston caries fluorine study4 further analysis ofdental findings including permanent and diciduous dentitions after 6 years of water
fluoridation.J#Am#!ent#A#1!5146#80ebruary9&1""$1!5.
6#. st (, hase *. Newburgh$Dingston caries fluoride study4 dental findings after si7years of water fluoridation. Oral Surg1!5428Can9&116$1#.
6. st (, +uschel , Wachs +, hase *. Newburgh Dinston caries fluorine study4
combined clinical and roentgen dental findings after " years of water fluoridation.JA!A1!554538Cune9&2"3$2"5.
66. st (, %mith (, Wac@s +, antwell D. Newburgh$Dingston caries fluorine study
>'B. ombined clinical and roentgenographic dental findings after 13 years of water
fluoride e7perience.JA!A1!5245#&16$#5.65. st (+, 0itEgerald +. -ffectiveness of water fluoridation.J Amer !ent A""
1!2#425&5"1$.
62. ta ). -ndemic fluorosis and dental caries in 'sparta 8Tur@ey9. Sch.ei/# M"chr#
0ahnheil+#1!55425869&6$5!.6. ttwood (, +lin@horn %. Trends in (ental *ealth of Ten$Jear$;ld %choolchildren
in %outh$West %cotland
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5". +arnes =), )ar@er W, /yon T, (rum , oleman =. -thnicity, /ocation, ge,
and 0luoridation 0actors in +aby +ottle Tooth$(ecay and aries )revalence of *ead$
%tart hildren.Public Health Report"1!!#4138#9&12$1.5!. +asting :T, )ereira , eneghim d. valiaFo da prevalncia de c rie dent ria em
escolares do unicLpio de )iracicaba$%), +rasil, apos #5 anos de fluoretaFo das guas de
abastecimento publico -valuation of dental caries prevalence in students from )iracicaba$%), +raEil, after #5 years of fluoridation of the public water supply.Rev# Odontol# 4niv#
S6o Paulo1!!41186 8out$deE99"$!#.
23. +eal C, Cames ). (ental caries prevalence in 5 year old children following five and ahalf years of water fluoridation in +irmingham$#"".$rit !ent J1!141389"6.
21. +eal C0, layton . 0luoridation a linical %urvey in orby and %cunthorpe -ngland
7iv. )renatal 0luorides$$Balue
of Waterborne 0luorides (uring )regnancy.J Am !ent A""oc1!2642!!1$6.
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2. +layney C, *ill '. 0luorine and dental caries.JA!A1!246$3#.
. +lin@horn , ttwood (, (owner . The effect of fluoridation on dental health of
urban %cottish schoolchildren.J (pidemiolCommunit' Health1!"145&!"$13.". +lin@horn , ttwood (, =avin =. Coint epidemiological survey on dental health of
1# year old children in (ublin and =lasgow. Communit' !ent Oral (pidemiol
1!!#4#3&3$".!. +ohannan *, =raves :, (isney C, %tamm CW, bernathy C+, +ader C(. -ffect
of secular decline in caries on the evaluation of preventive dentistry demonstrations. J
Public Health !ent1!"54658#9&"$!."3. +olin D, +olin , Cansson /, alltorp C. hildrenMs dental health in -urope $
%ociodemographic factors associated with dental caries in groups of 5$ and 1#$year$old
children from eight -
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!5. +rown *, )oplove . The +rantford$%arnia$%tratford 0luoridation aries %tudy&
0inal %urvey, 1!2. Can J Pub Health1!254528"9&1!$#6.
!2. +ruce *, =unter +. %tudy of effect on teeth of intemittant fluoridation of communitywater supply.J !ent Re"1!54#80ebruary9&5$65.
!. +runelle C. :ecent trends in dental caries in
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years fluoridation. Communit' !ental Health1!"641&6$56.
115. armichael , :ugg$=unn , 0errell :. The relationship between fluoridation,
social class and caries e7perience in 5 year old children in Newcastle andNorthumberland in 1!".$r !ent J1!"!412&5$21.
112. arr /. 0uoridation in anberra, '''. (ental caries after ten years.Au"trailian !ental
Journal1!24#1 8598;ctober9&663$666.11. arr %, (ooland , :oder (. 0luoridation ''4 an interim economic analysis.Au"t
!ent J1!"34#5829&6$6".
11". auley C, urphy ), :iley T, +lac@ (. )ublic health bonus of water fluoridation&(oes fluoridation prevent ostoporosis and its related fracturesOAmerican Journal o%
(pidemiolog'1!!1416&2".
11!. auley C, urphy ), :iley T, +uhari . -ffects of fluoridated drin@ing water on
bone mass and fractures& the study of osteoporotic fractures.J $one Min Re"1!!541389&132$"2.
1#3. avaliere :, Bantini . ?%tudy of the +ehavior of (ental aries in the 'nhabitants of
# Territories of %. mbrogio (i Balpolicella 8Berona9 With (rin@ing Water ontaining
Barious mounts of 0luorineA.*raca"toro1!2452&6#$3.1#1. (. Water 0luoridation and osts of edicaid Treatment for (ental (ecay $
/ouisiana 1!!5$1!!2.MMWR1!!!46"86 8%eptember99&5$5.1##. epe@ /, (ane@ C, *anusova %, )arma . 0luorosis in Eechoslova@ia.
Ca"op#le+#ce"+1!534"!8ugust 119&""$""!.
1#. hallacombe %C. (oes fluoridation harm immune functionO Communit' !ent Health1!!241 %uppl #&2!$1.
1#6. hegwin -. 0avourable results of fluoridation in oose Caw, %as@atchewan.
Canad J Public Health1!2145#&13$.
1#5. hen +. n epidemiological study on dental fluorosis and dental caries prevalencein communities with negligible, optimal and above$optimal fluoride concentrations in
drin@ing water supplies. Chni !ent J1!"!4"&11$#.
1#2. hen W, >u :, hen =, Hao C, hen C, 'nstitution& health and -pidemic )revention%tation of =uangdong )rovince =. hanges in the prevalence of endemic fluorosis after
changing water sources in two villages in =uangdong, hina.$ulletin o% (nvironmental
Contamination and Toicolog'1!!451869&6!$6"#.1#. hilvers . ancer mortality by site and fluoridated water supplies.J (pidemiol
Communit' Health1!"#42$6#.
1#". hilvers . ancer mortality and fluoridation of water supplies in 5
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%urface 'nde7 of 0luorosis. Communit' !ent Oral (pidemiol1!!54#8#9&"3$.
16. lar@ (, *ann *C, Williamson 0, +er@owitE C. -ffects of lifelong consumption
of fluoridated water or use of fluoride supplements on dental caries prevalence.Communit' !ent Oral (pidemiol1!!54#819$6.
15. lar@ (, +er@owitE C. The influence of various fluoride e7posures on the
prevalence of esthetic problems resulting from dental fluorosis.J Public Health !ent1!!4589&166$!.
12. lar@son C, ;Mullane (. modified ((- 'nde7 for
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156. oo@$oEaffari ). ancer and 0luoridation. Communit' !ental Health1!!241
%upplement #8%upplement #9&52$2#.
155. ooper , Wic@ham , /acey :, +ar@er (. Water fluoride concentration andfracture of the pro7imal femur.J (pidemiol Communit' Health1!!3466&1$1!.
152. ooper , Wic@ham , +ar@er (, Cacobsen %. Water fluoridation and hip fracture.
JAMA1!!14#22&51$516.15. orreia %ampaio 0, :amm von der 0ehr 0, rneberg ), )etrucci =igante (, *atloy
. (ental fluorosis and nutritional status of 2$ to 11$year$old children living in rural areas
of )araiba, +raEil. Carie" Re"1!!!4819&22$.15". ortes (0, -llwood :), ;mullane (, +astos C:(. (rin@ing water fluoride levels,
dental fluorosis, and caries e7perience in +raEil.Journal o% Public Health !enti"tr'
1!!2452869#2$##".
15!. ostache . ?'s the fluridation of water free of harmful effectsOA.)n%orm Med1!2146&163$12.
123. reighton W-, %avage C, Witter (. -ffect of 0luoridated Water in %chools
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water supply.Public Health Report"1!53425&163$163".
15. (ean *. lassification of ottled -namel (iagnosis.JA!A1!68ugust9&16#1$
16#2.12. (eatherage . study of fluoride domestic water and dental caries e7perience in
fluoride areas following the period of calcification on the prmanent teeth. 1!6.
1. (eatherage 0. 0luoride domestic waters and dental caries e7perience in #3#2 white'llinois selective servicemen.J# !ent Re"earch1!64##&1#!$.
1". (eatherage 0. study of fluoride domestic waters and dental caries e7perience in
#2 white 'llinois selective servicemen living in gluoride areas following the period ofcalcification of the permanent teeth.J# !ent# Re"earch ;;1!64##81$"39.
1!. (edney =, =ary :oEier :, /ess , *ughes C. Ten years of fluoridation in shville,
North arolina.,orth Carolina !ental Journal1!&11$12.
1"3. (e@@er . ?0luoridation of drin@ing waterA.,ederl T &enee"+1!2#415&66$.1"1. (emole B. 'odine, 0luorine, and Thyroid among school children in %witEerland.
$ull Sh.ei/ A+ad Med Wi""1!514&63.
1"#. (*%%. The 0luoridation %tudies in the
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nalysis and omparison of the /iterature.0 &e"amte H'g &ren/geb1!""46819&$2.
1!. (omEals@a -. ?aries incidence in school children in localities with different
fluoride concentrations in drin@ing waterA. C/a" Stomatol1!"418!9&"#5$".1!". (owner , +lin@horn , ttwood (. -ffect of fluoridation on the cost of dental
treatment among urban scottish schoolchildren. Communit' !ent Oral (pidemiol
1!"14!&11#$2.1!!. (owner , +lin@horn %, *olt :(, Wight , ttwood (. (ental caries
e7perience and defects of dental enamel among 1#$year$old children in north /ondon,
-dinburgh, =lasgow and (ublin. Communit' !ent Oral (pidemiol1!!64##85 )t 19"$5.
#33. (riscoll W%, *orowitE *%, eyers :C, *eifetE %+, Dingman , Himmerman -:.
)revalence of dental caries and dental fluorosis in areas with optimal and above$optimal
water fluoride concentrations.J Am !ent A""oc1!"413819&6#$.#31. (riscoll W, *orowitE *, eyers :. )revalence of dental caries and dental fluorosis
in areas with negligible, optimal, and above$optimal fluoride concentrations& a 5$year
follow$up survey.J Am !ent A""oc1!"2411!$.
#3#. du )lessis C+, van :ooyen CC, Naude (, van der erwe . Water fluoridation in%outh frica& will it be effectiveOJ !ent A""oc S A%r1!!54538119&565$!.
#3. (u7burry C. (ifferences in caries levels in 5$year$old children in Newcastle andNorth anchester.$r#!ent#J#1!"412#&65$65".
#36. -c@ v. )re$ and post$eruptive effect of fluoridated drin@ing water on dental caries
e7perience.
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(ental aries in dults Who onsume 0luoridated Bersus 0luoride$(eficient Water.J
Am !ent A""oc1!2642"&16$!.
#12. -nglander *:, (e)aola )0. -nhanced anticaries action from drin@ing watercontaining 5 ppm fluoride.J Am !ent A""oc1!!4!"819&5$!.
#1. -ric@son C(. ortality in selected cities with fluoridated and nonfluoridated water
supplies.,# (ngl# J# Med# 1!"4#!"8ay9&111#$1112.#1". -ric@son C(. 0luoridation and (own %yndrome.J !ental Re"
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Tenn State !ent A""oc1!25465&6"$5.
#2. 0orbes W0. =eochemical ris@ factors for mental functioning, based on the ;ntario
/ongitudinal %tudy of ging 8/%9 .2. The effects of iron on the associations ofaluminum and fluoride water concentrations and of p* with mental functioning, based on
results obtained from the /% and from death certificates mentioning dementia.
Canadian Journal On Aging>Revue Canadienne !u Vieilli""ement1!!412819&16#$15!.#. 0orrest C, )arfitt =, +randsby -. aries incidence among adults and young children
in high and low $fluorine areas in -ngland.Month#$ull#Min#Health
1!514138ay9&136$111.#". 0orrest C. ottled enamel and caries e7perience in fluoride and non$fluoride areas.
Proc# Ro'# Soc#Med1!5546"8November9&!"!.
#!. 0orrest C. 13 years of fluoridation.Month# $ull# Min# Health1!524158ay9&!$"#.
#63. 0orrest C. aries incidence and enamel defects in areas with different levels offluoride in drin@ing water.$riti"h !ental Journal1!524133&1!5$#33.
#61. 0orrest C:, Cames ). blind study of enamel opacities and dental caries
prevalence after eight years of fluoridation of water.$r !ent J1!25411!89&1!$##.
#6#. 0orsman +. -arly supply of fluoride and enamel fluorosis. Scand J !ent Re"1!4"5819#$3.
#6. 0orsyth +(. )revalence of (ental aries in )ermanent and )rimary Teeth -levenJears 0ollowing 0luoridation. a %tudy of 13,23 )rovidence, :.'. %chool hildren.R )
Med J1!2646&6"3$5.
#66. 0oul@es :=. ase report& ass fluoride poisoning, *ooper +ay, las@a& review ofthe final report of the las@a (epartment of *ealth and *uman %ervices, pril 1#, 1!!.
*luoride1!!64#819$2.
#65. 0oul@es :=. 'nvestigation of 'norganic 0luoride and 'ts -ffect ;n the ;ccurrence of
(ental aries and (ental 0luorosis in anada 0inal :eport. *luoride1!!54#"89&162$16".
#62. 0rada =, entesana =, =uaGana
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(eciduous (entition of a TanEanian
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Med J1!"34!#&126$.
##. =opala@rishnan ), Basan :, %arma ), Nair D, Than@appan D. )revalence of dental
fluorsis and associated ris@ factors in lappu7ha district, Derala.,atl Med J )ndia1!!!41#89&!!$13.
#. =oward )-. ottling on deciduous incisor teeth. study of 5$year$old Jor@shire
children from districts with and without fluoridation.$r !ent J1!"#4158139&2$!.#6. =raves :, +ohannan *, (isney C, %tamm CW, +ader C(, bernathy C:. :ecent
dental caries and treatment patterns in
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)revalence of (ental aries in hung$*sing New Billage Taiwan fter ! Jears.J
*ormo"an Med A""oc1!"64"8139&135$136.
#!3. =upta %D, =upta :, %eth D. :eversal of clinical and dental fluorosis. ),!)A,P(!)ATR# )ndian Pediatric"1!!641869&6!$66.
#!1. =upta %D, =upta :, %eth D, haturvedi %. 'ncreased incidence of spina bifida
occulta in fluorosis prone areas.ACTA PA(!)ATR JP, OV(RS (!# Acta PaediatricaJaponica Over"ea" (dition1!!54869&53$532.
#!#. =upta %D, =upta :, %eth D, =upta . :eversal of fluorosis in children.ACTA
PA(!)ATR JP, OV(RS (!# Acta Paediatrica Japonica Over"ea" (dition1!!24"859&51$51!.
#!. *aavi@@o D, *elle . The prevalence and distribution of enamel defects in with
different fluoride contents in the drin@ing water.Proceeding" o% the *inni"h !ental
Societ'E1EPROC# SOC#E31!643859&1"$1"5.#!6. *agan T, )asternac@ , %cholE =. Water$borne fluorides and mortality.Pub# Health
Rep#1!5642!8ay9&653$656.
#!5. *amdan , :oc@ W). The prevalence of enamel mottling on incisor teeth in optimal
fluoride and low fluoride communities in -ngland. Communit' !ent Health1!!14"8#9&111$!.
#!2. *ardwic@ C, Teasdale C, +loodworth =. aries increments over 6 years in childrenaged 1# at the start of water fluoridation.$r#!ent#J#1!"#415$###.
#!. *awley =, -llwood, :), (avies, :. (ental caries. fluorosis and the cosmetic
implications of different T0 scores in 16$year old adolescents. Communit' !ental Health1!!241&1"!$1!#.
#!". *ayes :. )ost$eruptive effects of fluoridation on first permanent molars in =rand
:apids. 1!5.
#!!. *ealth '(o). +ureau of statistics& mortality in fluoride and non$fluoride areas.%pringfield& The +ureau, 1!5#.
33. *easman , artin . ortality in areas containing natural fluoride in their water
supplies.Mon#$ull#Min#Health1!2#4#1&153.31. *eifetE %+, *orowitE *%. mounts of fluoride in self$administered dental products&
safety considerations for children.Pediatric"1!"24829&"2$"#.
3#. *eifetE %+, (riscoll W%, *orowitE *%, Dingman . )revalence of dental caries anddental fluorosis in areas with optimal and above$optimal water$fluoride concentrations& a
5$year follow$up survey.J Am !ent A""oc1!""4112869&6!3$5.
3. *eifetE %+, )ros@in *. %erendipitous results of a pilot study& precaution indicated.
J Clin !ent1!!542819&11$!.36. *eintEe %(, +astos C:, +astos :.
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1!"541!89"$#".
3!. *ill ', +layney C, Wolf W. -vanston dental caries study B'4 a comparison of the pre$
fluoride with post$fluoride caries e7perience of 2, and " year old children in the studyarea.J !ent Re"1!534#!8ugust9&56!$555.
13. *ill ', +layney C, Wolf W. -vanston dental caries study4 effect of artificially
fluoridated water on dental caries e7perience of 1#, 1 and 16 year old school children.J#!ent#Re"#1!51438;ctober9&23$25.
11. *ill ', +layney, Wolf N. -vanston dental caries study4 caries e7perience rates of 2,
and " year old children with progressively increasing periodsof e7posure to artificiallyfluoridated water.J# !ent# Re"earch1!5#418Cune9&62$5.
1#. *ill ', +layney C, Wolf W. -vanston dental caries study4 caries e7perience rates of
1#, 1 and 16 year old children after e7posure to fluoridated water for 5! to 3 months.J#
!ent Re"1!554680ebruary9&$"".1. *ill ', +layney C, Wolf W. -vanston dental caries study, reduction in dental caries
attac@ rates in children 2 to " years old.J# AM# !ent# A#1!52458%ept9$.
16. *ill ', +layney C, Wolf W. The -vanston (ental aries %tudy >B'''& :eport on the
permanent teeth dental caries e7perience rate of the children in the control area 8;a@)ar@, 'llinois9.Jounrnal o% !ental re"earch1!5"452&2""$!1.
15. *ill 'N, +layney C:, Wolf W. The -vanston (ental aries %tudy. >'>. )revalenceof malocclusion of children in a fluoridated and control area.J !ent Re"1!5!4"&"#$!6.
12. *ill ', +layney C, Wolf W. -vanston 0luoridation %tudy& Twelve Jears /ater. !ental
Progre""1!21418Canuary 8#99&!5$!!.1. *ill 'N, +layney C:. The -vanston (ental aries %tudy. #. ;ral /actobacilli and
(ecayed Tooth %urface :ates mong hildren in a 0luoridated rea.J !ent Re"
1!25466&1"$.
1". *illier %, 'ns@ip *, oggon (, ooper . Water fluoridation and osteoporoticfracture. Communit' !ental Health1!!2418%upplement #9&2$2".
1!. *illier %. Water fluoridation and fracture of the pro7imal femur.J $one and mineral
Re"1!!41#&15.#3. *illier %, opper , Dellingray %, :ussell =, *ughes *, oggon (. 0luoride in
drin@ing water and ris@ of hip fracture in the
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incidence and mortality& :eport to the (irector of the National ancer 'nstiture, 1!!3.
#". *oover :, (evesa %, antor D, 0raumeni C. :eview of 0luorides +enefits and :is@s,
ppendi7 0. Time trend" %or bone and ount cancer" and o"teo"arcoma" in theSurveillance (pidemiolog' and (nd Re"ult" 1S((R3 Program9 ,ational Cancer )n"titute#&
(epartment of *ealth and *uman %ervices,
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62. *utton W, /inscott +, Williams (. 0inal report of local studies on water
fluoridation. Cnad# J# Pub# Health1!52468arch9&"!$!#.
6. 'brahim J, ffan , +Gorvatn D. )revalence of dental fluorosis in %udanese childrenfrom two villages with 3.#5 and #.52 ppm fluoride in the drin@ing water.)nt J Paediatr
!ent1!!545869#$!.
6". 'iEu@a J, 'shida D, ra@awa *, sai J, *irata J,
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2#. Cacobsen %, ;M0allon W, elton /. *ip fracture incidence before and after the
fluoridation of the public water supply.Am J Pub Health1!!4"&6$65.
2. Cacmin$=adda *, ommenges (, /eteneur /, +arberger$=ateau ), (artigues C$0.omponents of drin@ing water and ris@ of cognitive impairment in the elderly.Am J
(pidemiol1!!641!&6"$5.
26. Cacmin$=adda *. 0luorine concentration in drin@ing water and fractures in theelderly.JAMA1!!54#&5$2.
25. Cacmin$=adda *, 0ourrier , ommenges (, (artigues C. :is@ factors for fractures
in the elderly.(pidemiolog'1!!"4!869&61$6#.22. Cames ). (ental caries prevalence in high and low fluoride areas of -ast nglia.$r
!ent J1!214113&125$!.
2. Cansen ', Thomson *. *eart deaths and fluoridation.*luoride1!64819&5#$5.
2". Cen@ins =N. 0luoride inta@e and its safety among heavy tea drin@ers in a +ritishfluoridated city.Proc *inn !ent Soc1!!14"869&51$5"3.
2!. Ciras@ova . 0luoridation of drin@ing water in cEechoslova@ia. '' :esults of
investigations prior to the e7perimental fluoridation in Tabor. C"l#Stomat1!23423K2&611$
61".3. Ciras@ova . ?0luoridation of drin@ing water as dental caries preventionA. Ce"+ H'g
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(epartment of *ealth, 1!26.
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