Systems biology of plant cell polarity
and leaf development
Industrial partners
TILL Photonics
University of Freiburg
Biologie II/BotanikZBSALMB
Our team
AG Palme, Ditengou, Dovzhenko, TealeAG FleckAG Ronneberger
Cell polarity regulation is used by sessile plants as a matter of flexible life style
Polarity regulation allows flexible responses
indole-3-acetic acid (IAA)
Polar auxin transport allows flexible adaptation of new functions
The PIN auxin efflux facilitator proteins enable flexibleredirection of auxin and enable local auxin accumulation
Atpin1
wt pin1
Characterization of polar auxin transporting micro-domains that orchestrate plant development.
How are they formed, how are they regulated ?
What is the functional auxin transport unit ?
Auxin transporting microdomains
PIN proteins are dynamic and loalized in microdomains
• share features with major facilitor super family• have a size of about 50 to 60 kDa• cycle between PM-EE-MVB and other compartments• PIN microdomains are distinct from plasmodesmata
Arabidopsis PIN proteins: markers of cell polarity
BFA Latrunculin
Atpin1
wt pin1