Download - The Ageing Cardiovascular System
![Page 1: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/1.jpg)
The Ageing Cardiovascular System
Jennifer Inglis12th December 2006
![Page 2: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/2.jpg)
Overview
Why is it important to understand ageing of the cardiovascular system?What changes in cardiovascular structure and function are associated with ageing?How might this affect our practice?
![Page 3: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/3.jpg)
Why?
Prevalence of cardiovascular disease amongst elderly populations“It’s just my age, doctor”Impact on our assessment and treatment of elderly patients
![Page 4: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/4.jpg)
What changes occur?
Vascular changesPostural changesCardiac changes at restCardiac changes on exercise
![Page 5: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/5.jpg)
![Page 6: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/6.jpg)
Vascular Changes
Aorta and large elastic arteries - wall thickness, dilation and stiffening in mean systemic arterial pressure in most, but not allSystolic BP rises more than diastolic – increasing chance of isolated systolic hypertension
![Page 7: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/7.jpg)
Postural Changes
Blunting of in HRSlowed baroreceptor response to postural changeMay be reduced vasoconstriction in response to reduced BPIncrease the chance of postural hypotension
![Page 8: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/8.jpg)
![Page 9: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/9.jpg)
Cardiac Changes at Rest
Minor in HRCO output maintained by SV ejection of blood during late systole early diastolic filling rateEDV not - enhanced atrial contribution to LV filling – beware AF, particularly if tachycardic
![Page 10: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/10.jpg)
During exercise…
in maximum HR ( response to β-adrenergic stimuli) in cardiac output - reduced by 30% between ages 20 and 80Maximum SV not reduced – but maintained in different mannerFrank Starling mechanism
![Page 11: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/11.jpg)
Frank Starling Mechanism
EDV, due to:Longer diastolic interval ( HR) EF - amount of blood in LV at start of diastole
![Page 12: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/12.jpg)
Summary of changes
HR SV CO EDV EF
At rest = = =
Exercise =
![Page 13: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/13.jpg)
![Page 14: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/14.jpg)
Some Practical Points
Beware of increased risk of hypertension……and postural hypotensionElderly patients unlikely to tolerate tachycardia or AF as well as younger patientsCaution with beta blockers
![Page 15: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/15.jpg)
In summary…
Ageing does alter the structure and function of the cardiovascular systemChanges more evident during exerciseThese effects may contribute to earlier decompensation when unwell…and remember your erect and supine BPs!
![Page 16: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/16.jpg)
Comments?
Or easy questions?
![Page 17: The Ageing Cardiovascular System](https://reader036.vdocument.in/reader036/viewer/2022081603/56815be3550346895dc9d45a/html5/thumbnails/17.jpg)