The Kidneyyour bodies blood filter
The Kidney Ultrafiltration: filter the blood plasma
through the glomerulus and fenestrated capillaries
Increase in blood pressure in the glomerulus drives the filtration process
The fenestrations (slits) open up as blood flows through at high pressure
The basement membrane is not permeable to larger molecules, preventing things like protein enter the filtrate
The Kidney Osmoregulation is the homeostatic
process of controlling water levels in all tissues in your body
Why is it necessary?
Regulating the water levels will allow blood cells to remain in tact
The KidneyThe kidney is almost too good at filtering your blood… Much of what initially gets filtered out has to be returned
Most noteworthy substances to be reabsorbed: water, salts, glucose If water wasn’t reabsorbed you’d be peeing a lot more!
Much of reabsorption occurs via osmosis and diffusion, some via active transport (needs ATP)
The Kidney
The Kidney With ADH NOT available, water
stays in the filtrate/urine
With ADH present, water leaves, urine production decreases/becomes more concentrated
The Kidney
Diabetics can often have glucose in their urine
Not normal…typically 100% of glucose reabsorbed
Cotransport (active) of glucose against gradient has a capacity—too much glucose ends up in urine