Undifferenciated sarcoma
2012-05983 MH
• Female 67 years old
• Weight loss 15 kg
• Self palpation a mass of proximal thight
2012-05983 MH
2012-05983 MH MRI April 2012
Per cutaneous biopsy•Undifferenciated sarcoma•Grade 3
Chest CT: Normal
2012-05983 MH
Ki-67
2012-05983 MH
67 years oldMRI April 2012
What do you propose?
• Front line surgery?
• Radiotherapy?
• Chemotherapy?
2012-05983 MH
What do you propose?
• Front line surgery?
• Radiotherapy?
• Chemotherapy?
A 60 mg/m2 J1
I: 3g/m2 J1 J267 years oldMRI April 2012
June 2012: post 2 cycles CT: + 3 cm2012-05983 MH
What do you propose?
• Surgery?
• Radiotherapy?
• 2nd line chemotherapy?
October 2012: Post RT 50 Gy: - 2 cm2012-05983 MH
• 15 X 7 cm• Femoral nerve is included• Vessels partially included• 8% residual tumour cells• R0 1 mm
• Pathology
2012-05983 MH
June 2014: MRIChest CT: normal+ 2 years
2012-05983 MH