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1 | VARIAN PARTICLE THERAPY
Varian Particle TherapyDavid E. Mellenberg, Ph.D. DABR
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2 | VARIAN PARTICLE THERAPY
>1100ProBeam™
PSI – Paul Scherrer Institute
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3 | VARIAN PARTICLE THERAPY
>1,500ProBeam™
Rinnecker Proton Therapy Center
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4 | VARIAN PARTICLE THERAPY
2ProBeam™
Scripps Proton Therapy Center
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5 | VARIAN PARTICLE THERAPY
ProBeam™ Key Features
2nd Generation IMPTPencil Beam 4 mm σDose Rate 2 Gy/L/Min
Dynamic PeakTM
Scanning
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6 | VARIAN PARTICLE THERAPY
ProBeam™ Key Features
Dynamic PeakTM
Scanning
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7 | VARIAN PARTICLE THERAPY
Dynamic Peak™ ScanningPrecision
80 100 120 140 160 180 200 220 2403,0
3,5
4,0
4,5
5,0
5,5
6,0
sigm
a (m
m)
Energy (MeV)
sigma-x sigma-y
4 mm
1 mm
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8 | VARIAN PARTICLE THERAPY
30 cm
40 c
m
-20
-15
-10
-5
0
5
10
15
20
-20 -10 0 10 20
Y (c
m)
X (cm)
Film Plan
Dong/Scripps
Large Field AccuracyScripps Proton Therapy Center
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9 | VARIAN PARTICLE THERAPY
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10 | VARIAN PARTICLE THERAPY
ProBeam™ Key Features
• On-board 2D & CBCT• Dedicated User Interface• I-Lab Development• TrueBeam Roadmap
Dynamic PeakTM
Imaging
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11 | VARIAN PARTICLE THERAPY
Dynamic Peak™ ImagingKey Features
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12 | VARIAN PARTICLE THERAPY
Dynamic PeakTM ImagingBiplanar Imaging Panels
CBCT Capable
Robotic
Image Analysis
Integrated Hardware
Integrated Software
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13 | VARIAN PARTICLE THERAPY
Dynamic Peak™ ImagingKey Features
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14 | VARIAN PARTICLE THERAPY
Dynamic Peak™ ImagingDeformable Registration
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15 | VARIAN PARTICLE THERAPY
ProBeam™ Key Features
TrueBeam™ ConsoleTherapy Hand PendantGuided WorkflowField Groups
Dynamic PeakTM
Workflow
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16 | VARIAN PARTICLE THERAPY
ProBeam™
Image Guided Proton Therapy
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17 | VARIAN PARTICLE THERAPY
Dynamic PeakTM WorkflowCommon User Interface – Guided Workflow
Console Pendant
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18 | VARIAN PARTICLE THERAPY
ProBeam™ Key Features
• Lessons learned conventional RT
• Multiple Strategies• Monitored Breath Hold,
Motion Scanning, Gating, Tracking, Triggered Imaging
Dynamic PeakTM
Motion Management
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19 | VARIAN PARTICLE THERAPY
Intra-fraction Motion
No MotionAmplitude under x mm
MotionAmplitude over x mm
Interplay EffectHot and cold spots
Also an issue for IMRTNot present with scattering
Position EffectMissing the target
Scanning DirectionLei Dong: solves 90% of issues
Ready to publish
RepaintingTony Lomax: 2 times layer
4D simulation
ITV TreatmentLarger margins around targetDominant strategy in photons
GatingSelecting part of the motion cycle
Vision RT Calypso Triggered Imaging
Auto Beam Hold
RPM
DeformationChange of tumor geometry
CBCTDetect deformation
Def- registration
Adaptive treatmentRe-plan, online or offline
After y fractions
Dynamic PeakTM Motion ManagementOverview
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20 | VARIAN PARTICLE THERAPY
Varian Medical SystemsVision