Download - What controls cell growth Objective: To study limits on cell growth and why cancer occurs in cells
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What controls cell growth
Objective: To study limits on cell growth and why cancer occurs in
cells
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What controls cell growth?
Cells will typically divide until they are touching
When your skin is torn the cells will divide until they are touching again
healing
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What tells cells to divide
Cyclin- protein that regulates timing of cell cycle (in eukaryotes)
Internal Regulators- proteins that respond to an event inside the cell
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What tells cells to divide cont.
External Regulators- Proteins that respond to an event outside the cell
Growth Factors- important during embryonic development and wound healing
Also helps prevent excessive growing
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Uncontrolled cell growth
Uncontrolled cell growth- cancer
Cancer cells do not respond to signals that regulate normal cell growth
Cancer cell- form tumors- cancer cells break loose from tumor and spread throughout the body
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Uncontrolled cell growth
Some cancers are due to a problem with internal or external regulators
Most cancer cells have a defect in the P53 gene
Causes cell to lose info needed to respond to signals that would normally control growth.
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Cancer Stats.
Most common cancer in US
Skin cancer
Cancer that kills most people in US
Lung cancer
Both are preventable in most cases
1/3 people are likely to get cancer