dr bob's alcohol and drug lecture

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    Dr BobsDr BobsAlcohol and Drug Addiction LectureAlcohol and Drug Addiction Lecture

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    Drug AddictionDrug Addiction

    1818 20% of the U.S. Population20% of the U.S. Populationsuffers from drug and/orsuffers from drug and/oralcohol addictionalcohol addiction

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    COST:COST:

    3 Billion Dollars Annually due to3 Billion Dollars Annually due tohealthcare costs and/or job losshealthcare costs and/or job loss

    20% patients of medical facilities20% patients of medical facilities

    3535 55% psychiatric patients55% psychiatric patients

    20% family medicine patients20% family medicine patients

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    Addiction DisorderAddiction Disorder

    Not enough Government ProgramsNot enough Government Programs

    Not enough Government FundsNot enough Government Funds

    Not enough Government ConcernNot enough Government Concern

    Not enough ResearchNot enough Research

    Not enough Prevention Programs

    N

    ot enough Prevention Programs

    Public awareness for early treatment is vital.Public awareness for early treatment is vital.

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    AlcoholAlcohol Second on the list of most used substances worldSecond on the list of most used substances world

    wide (Smoking is 1wide (Smoking is 1stst on the list)on the list)

    #1 cause of MVA#1 cause of MVA

    Morbidity (illness)Morbidity (illness)

    DeathsDeaths

    #1 cause of household#1 cause of household

    accidents/violence/homicidesaccidents/violence/homicides Enormous cost to the individual and to societyEnormous cost to the individual and to society

    Enormous number of deaths directly caused byEnormous number of deaths directly caused byOverdose of EthanolOverdose of Ethanol

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    DeathsDeaths 50,000 Alcohol/Drug Related Deaths per year50,000 Alcohol/Drug Related Deaths per year

    550,000 Smoking Related Deaths per year in the550,000 Smoking Related Deaths per year in theU.S. (Not including 50,000 due to exposure toU.S. (Not including 50,000 due to exposure to

    second hand smoke)second hand smoke) Causes of Ethanol Related Deaths:Causes of Ethanol Related Deaths:

    SeizuresSeizures

    M.I.sM.I.s

    CNS DepressantCNS Depressant

    Asphyxia/AspirationAsphyxia/Aspiration

    Aortic DissectionAortic Dissection

    Dosed related vs. Overdose relatedDosed related vs. Overdose related

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    Alcohol Related Deaths per 100,000 peopleAlcohol Related Deaths per 100,000 people

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    Etiology of AddictionEtiology of Addiction

    HereditaryHereditary Approximately 6Approximately 6--10%10%(additional research pending)(additional research pending)

    AddictionAddiction Physical DiseasePhysical DiseasePsychosocial PressuresPsychosocial Pressures

    Neurological Brain Age ExposureNeurological Brain Age Exposure

    Behavioral PathologyBehavioral PathologyDysfunctional Family UnitDysfunctional Family Unit

    Psychiatric Disorders (DualPsychiatric Disorders (Dual--Diagnosis)Diagnosis)

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    EthanolEthanol Brain/CNSBrain/CNS

    Begins with mild Euphoria/ Loss of inhibitionBegins with mild Euphoria/ Loss of inhibition Behavioral, EmotionalBehavioral, Emotional

    Impairs: judgment, memory, concentration,Impairs: judgment, memory, concentration,coordinationcoordination

    Further intake/CNS Capture leads toFurther intake/CNS Capture leads to Mood SwingsMood Swings

    Emotional OutburstsEmotional Outbursts

    Decreased: vision, hearing, smell, taste,Decreased: vision, hearing, smell, taste,Fine/gross motor skills, reactionsFine/gross motor skills, reactions

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    EthanolContd:EthanolContd: Large/Heavy DosesLarge/Heavy Doses

    Induces Sleep (defense mechanism)Induces Sleep (defense mechanism)

    Anesthesia for the bodyAnesthesia for the body

    SeizuresSeizures Dulls, Depresses, Alters, Damages Brain CellsDulls, Depresses, Alters, Damages Brain Cells

    Respiratory FailureRespiratory Failure

    ComaComa

    DeathDeath

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    EthanolContd:LIVEREthanolContd:LIVER 11stst organ affected due to frequency of alcohol useorgan affected due to frequency of alcohol use

    Metabolism (Breaks down Ethanol)Metabolism (Breaks down Ethanol)

    Inflammation/swelling/destruction of liver cellsInflammation/swelling/destruction of liver cells(Hepatitis)(Hepatitis)

    CirrhosisCirrhosis severe and possibly irreversible destructionsevere and possibly irreversible destructionof liverof liver

    Reduction of ClottingReduction of Clotting

    Reduction of ImmunityReduction of Immunity

    Reduction of Metabolism (Nutrients, Vitamins)Reduction of Metabolism (Nutrients, Vitamins) Increase fat deposits and circulationIncrease fat deposits and circulation

    FailureComaDEATHFailureComaDEATH

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    Death Rates ofLiverCirrhosis bySexDeath Rates ofLiverCirrhosis bySex

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    EthanolContdEthanolContdSexual/Reproductive Functions:Sexual/Reproductive Functions:

    Sexual response impairedSexual response impaired

    ImpotenceImpotence

    InfertilityInfertilityF.A.S. (Fetal Alcohol Syndrome)F.A.S. (Fetal Alcohol Syndrome)

    Physical AbnormalitiesPhysical AbnormalitiesDecreased Muscle/ToneDecreased Muscle/Tone

    Decreased SpeechDecreased Speech

    Decreased IntelligenceDecreased Intelligence

    Decreased GrowthDecreased Growth

    Higher Risk of Breast Cancer

    H

    igher Risk of Breast Cancer

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    Areas of the Brain Affected by FASAreas of the Brain Affected by FAS

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    OpiatesOpiates Forms of AdministrationForms of Administration

    P.O. (By Mouth)P.O. (By Mouth)

    IV/IM/SQ/ skin popping/ muscleIV/IM/SQ/ skin popping/ muscle--inin--itit

    (Infection)(Infection) InhalationInhalation Smoked/ Nasal InhalationSmoked/ Nasal Inhalation

    Rectal/ SuppositoryRectal/ Suppository

    Highly AddictiveHighly Addictive Often prescribed by Medical ProfessionalsOften prescribed by Medical Professionals

    UnawareUnaware becoming abusive/ dependentbecoming abusive/ dependent

    Affects strong binding sites in brain & body (wholeAffects strong binding sites in brain & body (whole

    effect)effect)

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    OpiatesContdOpiatesContd

    Opiate Receptors (sites of opiod binding)Opiate Receptors (sites of opiod binding)

    Mu, kappa, delta, sigmaMu, kappa, delta, sigma

    Affecting many neuroAffecting many neuro--substances like:substances like:

    EnkephalinsEnkephalins

    EndorhphinsEndorhphins DynorphinsDynorphins

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    OpiatesContd:OpiatesContd:WithdrawalEffectsWithdrawalEffects

    Abdominal CrampsAbdominal Cramps

    AnorexiaAnorexia

    AnxietyAnxiety

    InsomniaInsomnia

    DysphoriaDysphoria

    NauseaNausea

    TearingTearing

    HeadachesHeadaches

    High B.P.High B.P.

    IrritabilityIrritability

    DiarrheaDiarrhea

    Hot/Cold FlashesHot/Cold Flashes

    PsychosisPsychosis

    Muscle Aches/SpasmsMuscle Aches/Spasms

    DepressionDepression

    VomitingVomiting

    Runny NoseRunny Nose

    RestlessnessRestlessness

    TachycardiaTachycardia

    AgitationAgitation

    Takes days/weeks/months before feeling betterTakes days/weeks/months before feeling better

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    Opiates/NarcoticsOpiates/NarcoticsAnalgesicsAnalgesics

    Derived from Opium/PoppyDerived from Opium/Poppy

    Papaver Somniferum =H

    eroinPapaver Somniferum =H

    eroinMorphineMorphine CodeineCodeine

    Chemical Isolation by Germans duringChemical Isolation by Germans duringWWII because of lack of MorphineWWII because of lack of Morphine

    Now SemiNow Semi--Synthetic productsSynthetic products MeperidineMeperidine--DemerolDemerol--HysromorphineHysromorphine

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    TreatmentOptionsTreatmentOptions Treatment:Treatment: None!None!

    Management:Management: Much!Much!

    Treatment Programs:Treatment Programs:1.1. Full InpatientFull Inpatient Expensive but very goodExpensive but very good

    2.2. Day CareDay Care SemiSemi--ExpensiveExpensive goodgood

    3.3. I.O.P. (Intensive Outpatient Program) lessI.O.P. (Intensive Outpatient Program) less

    expensiveexpensive good depending on yourgood depending on yourmotivationmotivation

    4.4. Relapse PreventionRelapse Prevention Weekly, BiWeekly, Bi--WeeklyWeekly

    5.5. Partial ProgramPartial Program Weekly, BiWeekly, Bi--WeeklyWeekly

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    Medical DetoxificationMedical Detoxification

    Inpatient vs. OutpatientInpatient vs. Outpatient

    Multiple Medications:Multiple Medications:

    Benzodiazepines/ Barbiturates:Benzodiazepines/ Barbiturates:Anxiety/AgitationAnxiety/Agitation

    Methocarbomol/ Flexeril (Cyclobenzapine)/Methocarbomol/ Flexeril (Cyclobenzapine)/

    Skelaxin (Metaxalone): Muscle RelaxantsSkelaxin (Metaxalone): Muscle Relaxants Lomotil (Diphenoxylate/ Atropine)/ ImmodiumLomotil (Diphenoxylate/ Atropine)/ Immodium

    (Loperamide): Anti(Loperamide): Anti--diarrhealdiarrheal

    Bentyl (Dicyclomide)Bentyl (Dicyclomide)

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    Suboxone/Sebutex (Buprenorhine)Suboxone/Sebutex (Buprenorhine)

    Partial Agonist/Antagonist OpiatePartial Agonist/Antagonist Opiate

    Excellent for Maintenance ManagementExcellent for Maintenance Management

    SuboxoneSuboxone

    2 or 8 mg sublingual breakable tablets2 or 8 mg sublingual breakable tablets

    Plus 0.5 mg or 2mg Naloxone (Narcan)Plus 0.5 mg or 2mg Naloxone (Narcan)

    Blocker effect against I.V. drug abuseBlocker effect against I.V. drug abuse Take once or twice dailyTake once or twice daily

    Doctor prescribing must be certifiedDoctor prescribing must be certified

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    MaintenanceManagementMaintenanceManagement

    Depends on age of onset/ period of useDepends on age of onset/ period of use

    Depends on drug history andDepends on drug history and

    dysfunctional diseasedysfunctional disease

    Depends on relapse frequencyDepends on relapse frequency

    Depends on detox/ treatment failuresDepends on detox/ treatment failures

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    MaintenanceMaintenance: Advantages ofManagement: Advantages ofManagement

    SobrietySobriety For opiod agonists (buyingFor opiod agonists (buyingtimetime

    Motivates control over their livesMotivates control over their livesMotivates family unity in their livesMotivates family unity in their lives

    Motivates completion & understanding ofMotivates completion & understanding of

    better treatment programsbetter treatment programsMotivates adhering to AA, NA, CA, PAMotivates adhering to AA, NA, CA, PA

    Motivates adhering to compliancy withMotivates adhering to compliancy withother medicationsother medications

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    AdvantagesContdAdvantagesContd

    Motivates compliancy with own healthMotivates compliancy with own healthand welland well--beingbeing

    Motivates finding and keeping a jobMotivates finding and keeping a job

    Motivates a better marital relationshipMotivates a better marital relationship

    Motivates a greater sense of faithMotivates a greater sense of faith

    Motivates to mend all aspects of theirMotivates to mend all aspects of theirlife!!!life!!!

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    Avoid:Avoid:

    HIV, Hepatitis C/B Exposure, STDsHIV, Hepatitis C/B Exposure, STDsand/or Hospitalizationsand/or Hospitalizations

    Lying, Manipulation, Stealing, etc.Lying, Manipulation, Stealing, etc.

    OverOver--spendingspending

    Using other substancesUsing other substances

    Injury, accidents, legal courts, jailInjury, accidents, legal courts, jail