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Dr Vlasis Ninios St. Luke’s Hospital Thessaloniki 2018

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Page 1: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Dr Vlasis Ninios

St. Luke’s Hospital

Thessaloniki

2018

Page 2: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 3: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 4: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 5: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 6: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

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Edge-to Edge repair with the MitraClip (Abbott Vascular)

Page 8: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 9: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

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Kaplan-Meier Freedom from MV Surgery in MitraClip group or Re-operation in Surgery group

All Treated Patients (N = 258) – Landmark Analysis

RCT MitraClip Non-High Risk (N = 178)

RCT Surgery Non-High Risk (N = 80)MitraClip Non-High Risk (N = 178)

Surgery Non-High Risk (N = 80)

MitraClip (N = 178)

Surgery (N = 80)

98.7%97.1%

97.2%96.3%

1 year 2 years

95.6%95.5%

3 years

10809007205403600 180

Days Post Index Procedure

Page 11: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 12: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 13: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 14: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 15: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 16: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 17: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 18: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 19: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 20: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

Page 21: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

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(97)

Page 23: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

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Total

MR etiology

Functional MR Degenerative MR Mixed Etiology

65.6%

20.8%

13.6%

-EMEA sites-

FMR

DMR

85

15%

Page 25: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Baseline 30 days

4+

3+

4+

1+

2+

Page 26: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Baseline 30 days

NYHA IV

NYHA III

NYHA II

NYHA I

III

IV

IV

III

II

I

Page 27: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

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Page 31: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

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Moderate MR after 2 clips… Patient had tremendous improvement

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Final Result

BEFORE AFTER

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88 Y. OLD PATIENT-ISCHEMIC CARDIOMYOPATHY- RECENT PULMONARY OEDEMA

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GRASP A3-P3

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GRASP A3-P3

1ST GRASP 2ND GRASP

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GRASP A2-P2

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FINAL RESULT

BEFORE AFTTER 2 CLIPS

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A2-A3 PROLAPSE

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1ST CLIP A3-P3

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2ND CLIP A2-P2

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FINAL RESULT

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FINAL RESULT

BEFORE AFTER

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Page 50: Dr Vlasis Ninios - Livemedia.gr · 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Baseline 30 days NYHA IV NYHA III NYHA II NYHA I III IV IV III II I

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