Drill: Draw: 2-amino-4-

hydroxybutanoic acid

Ether•R1-O-R2

•CH3-CH2-O-CH3

•Ethylmethyl ether

Common Ethers

•CH3-CH2-O-CH2-CH3

•Diethyl ether

•General anesthetic

Common Ethers

•Diphenyl ether

O

Heterocyclic Ethers

Heterocyclic•A carbon ring structure

with an element other than carbon in the ring

Furan

O

Tetrahydrofuran

O

Pyran

Tetrahydropyran

Epoxide O

C C

Epoxyethane O

H2C CH2

Epoxide Addition Reaction O

C C + H-O-H

HO OH

-C C-

HCl

hydration

Epoxide Reaction O

H2C CH-CH3+H2O HCl

1,2-Propanediol

HO OH

H2C CH-CH3

O

HO

cannabinol

O

HO

tetrahydrocannabinol

Drill: Draw the reactants, then predict,

draw, & name the major organic products in the

dehydration of2-pentanol.

AlkoxidesSimilar to hydroxides, but with an alkane

H-O-

R-O-

AlkoxidesAlkoxides are used to

make ethers

Making Alkoxides•Add an alkali metal

to an alcohol

•Alkoxide: R-O-

Alkali + Water

H-O-H + M

M+ + H-O- + H2

Making Alkoxides

R-OH + M

M+ + R-O- + H2

Alkoxide Example

-OH + K

Alkoxide Example

-O- + K+ + H2

Making Ethers•Alkoxides + alkyl halides

•R1-O- + R2-X

• R1-O-R2 + X-

Making Ethers

CH3-CH2-O- + CH3-I

CH3-CH2-O-CH3 + I-

Predict & Name Products

CH3-CH2-O-

+ CH3-CH2-I

Organic HWPredict & draw theorganic products

F-CH2-CH2-CH2-CH2-O-

Making Ethers

F-CH2-CH2-CH2-CH2-O-

O + F-

Organic Quiz:Name reactant, then Predict & draw theorganic products

I-(CH2)5-O-