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PSME3 PSME3FAT1 FAT1TNFRSF10B TNFRSF10BS100A6 S100A6COPS5 COPS5MUC1 MUC1RCAN1 RCAN1PNMA1 PNMA1TOX4 TOX4CHD4 CHD4CSNK1G3 CSNK1G3RAF1 RAF1MAPK1 MAPK1CSDE1 CSDE1NCOR1 NCOR1HPRT1 HPRT1ITCH ITCHCRAT CRATSP1 SP1FOXA1 FOXA1ASPM ASPMIDH2 IDH2ACSL3 ACSL3CHUK CHUKRALGPS2 RALGPS2KRAS KRASTRIP10 TRIP10FANCI FANCICNOT1 CNOT1SMARCB1 SMARCB1NCOR2 NCOR2S100P S100PSTAG1 STAG1ZNF292 ZNF292
HTR2B HTR2BRORA RORAEPHB2 EPHB2ARHGAP26 ARHGAP26BATF BATFIL6R IL6RVIM VIMGBP1 GBP1DNM1 DNM1UBASH3B UBASH3BTRERF1 TRERF1MASP2 MASP2ST6GAL1 ST6GAL1LCN2 LCN2NLRC5 NLRC5EGFR EGFRBCOR BCORGABBR1 GABBR1ICOSLG ICOSLGINPP4A INPP4AREPS2 REPS2FLT3LG FLT3LGANTXR1 ANTXR1DEPDC5 DEPDC5UTY UTYIL11RA IL11RACTSS CTSS
FUT7 FUT7BEND5 BEND5CCR4 CCR4RUNX3 RUNX3NIPSNAP3B NIPSNAP3BIFNA10 IFNA10NTRK1 NTRK1RNASE2 RNASE2SLCO5A1 SLCO5A1SLAMF1 SLAMF1CCR10 CCR10GLI2 GLI2CYTIP CYTIPCDH5 CDH5GZMM GZMMFGF2 FGF2ABCB1 ABCB1BNC2 BNC2MAGEA11 MAGEA11NCAM1 NCAM1CD180 CD180FPR1 FPR1DOCK2 DOCK2NLRP3 NLRP3PCSK5 PCSK5PDGFRA PDGFRAPTPRC PTPRCIL13RA2 IL13RA2LHCGR LHCGRCD52 CD52IL17F IL17FZBTB32 ZBTB32IFNB1 IFNB1CSF2RB CSF2RBHAL HALGPR171 GPR171SERPING1 SERPING1IL1A IL1AFLT1 FLT1AZU1 AZU1HLA-DPA1 HLA-DPA1MMP9 MMP9CXCL6 CXCL6CD7 CD7IGJ IGJFYB FYB
MCF7
RNA-Seq Driver-Map™ Profile
HIGHLYABUNDANT
MEDIUMABUNDANT
LOWABUNDANT
231 436 453 468 BR3 T47D ZR75 MCF7 231 436 453 468 BR3 T47D ZR75
20191817161514131211109876543210
READS(log2)
Driver-Map™ Targeted RNA Expression Profiling Solution
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Cellecta is a trusted provider of genomic products and services. Our functional genomics portfolio includes gene knockout and knockdown screens, custom and genome-wide CRISPR and RNAi libraries, construct services, cell engineering, NGS kits and targeted expression profiling products and services.
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Sylvain Baron, Ph.D.Poster: CRISPR/Cas9 genome-wide sgRNA libraries for loss-of-function and gain-of-function genetic screens
Sunday, April 2, 2017, 1:00-5:00 p.m.Halls A-C, Poster Section 17 Poster Abstract: 403 / 3
Paul Diehl, Ph.D.Presentation: Driver-Map™ Assay: Gene expression profiling of protein-coding genes for tumor microenvironment analysis and biomarker discovery
Tuesday, April 4, 2017, 10:00-11:00 a.m. Spotlight Theatre B – Hall A
Andrey Komarov, Ph.D.Poster: Profiling of immunity biomarkers in whole blood
Tuesday, April 4, 2017, 1:00-5:00 p.m.Halls A-C, Poster Section 28 Poster Abstract: 4652 / 13
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Robust, single-tube assay for a wide range of complex applications
• Biomarker Discovery from Whole Blood Samples– globin or rRNA depletion step not needed
• CTC Detection in Whole Blood – no CTCenrichment required
• Tumor Cellular Composition Analysis – highsensitivity profiling of tumor, stromal andinfiltrating immune cell types with nocell separation
• Expression Profiling of PDX Models – human- specific expression «profiling without
interference from mouse background cells