driving innovation and strategic excellence in the life...
TRANSCRIPT
![Page 1: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/1.jpg)
DrivingInnovationAndStrategicExcellenceintheLifeSciences
CarlosNVelez,Ph.D.ManagingPartnerLacertaBioInc.
[email protected]+18452933343
![Page 2: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/2.jpg)
OurPracticeAreasAreDedicatedToServingTheBusinessDevelopmentCommunity
Weruncompletein-licensingandout-licensingprocesses,utilizingasuiteofapproachestomaximizetheprobabilityoflicensingsuccess.
WeconsulttoBD&Lteamsbyprovidingduediligencesupport,valuation,secondopinions,andprocessaudits.
OutsourcedLicensing Consulting
2
OurPractice
![Page 3: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/3.jpg)
OurConsultingPractice
3
• ProductDevelopment• IntellectualProperty• MarketOpportunityAssessments
• ProductIn- andOut-Licensing• ProductandCompanyFundRaising• Duediligencesupportforinvestors
• InterimandFullTimeManagement• TurnAroundSituations• TemporaryManagementSupport
Weadviseonproductdevelopmentandcommercialopportunities.
Wesource andassessnoveltechnologies,orfindpartnersforourclients’innovations.
WeFocusOnWhatMattersMostToSeniorManagementAndTheirInvestors
3
Weexecutecompanyturnarounds,orprovideinterimmanagementservices.
![Page 4: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/4.jpg)
OurOutreachFramework
4
WhetherIn- orOut-Licensing,WeUtilizeMultipleChannelsForMaximizingCommunication
• PassiveMarketing– IndividualpagesonLacertaBio.commarketedviaLinkedInandotherdigitalchannels
• Databases – Pastconferences,MedTrack…
• ActiveOutreach– Callstocompanieswithexpressedinterestintherapeuticareaorasset,plusnewsletterwith3000+recipients
• Conferences – RepresentationatBiotechShowcase,BIO,andBIOEuropeFallincludedinfees
• Client/LacertaBioIdeas– PriorcontactsandrelationshipsandVCs
![Page 5: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/5.jpg)
WeIncreasethePaceofBDThroughaCompletelyOutsourcedApproach
5
ExecutivesWantFasterBDWithoutMajorIncreasesinExpenses.WeProvideThisSolution.
Situation
• Managementneedstoefficiently increasein- andout-licensingcapabilitiesanddealflow
• AmplesupplyofexperiencedBDprofessionalsavailable
• Demandforqualityassetswithattractivecommercialpotentialandaclearly-definedriskprofilehasneverbeengreater
Challenges
• InvestorsdemandfasterBD&L,distractingmanagementfromkeyoperationaltasks
• HiringBDtalentisexpensive,risky,andtime-consuming
• Needtoemphasizecommercialbenefitsandriskstoprospectivepartners
OurSolution
• WeprovidetheBDservicesneeded,enablingmanagementtofocusonotherareasofthebusiness
• OutsourcedBDledbyindependent,seasonedprofessionals
• Materialsandprocessesemphasizecommercialbenefitstoprospectivepartner,unclutteredbytechnicaldetails
![Page 6: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/6.jpg)
ConsultingCaseStudy:ValuationForLicensing
Situation
• CanadianpharmaceuticalcompanywithaPreclinicallicensingopportunity
• NegotiatingalicensingdealwithaChinesepharmaceuticalcompany
• NeedforChina-specificmarketassessment,valuation,anddealanalysis
Challenges
• Reformulationofexistingdruginahighlycompetitive,price-sensitivemarket
• ChinesecompanypreferringtransactionbasedonSales,notUpfronts &Milestones
• ChinesehealthcaresystemamysterytomanyNorthAmericansandEuropeans
OurSolution
• Emphasisofclinicalbenefitstonewproduct,andresultingcost-savings
• On-the-groundanalystsinChinawhounderstandlocalsystem
• BlendofUSandChinesedatasourcestoarriveatreasonablevaluationanddealterms
OurGlobalReachEnablesLacertaBioToConductMultinationalValuationExercises
6
![Page 7: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/7.jpg)
DrugDeliveryLicensingPresentsSpecialChallenges
Situation
• Drugdeliverytechnologycompaniesfrequentlyhavealargeportfolioofprojects
• Rangefromideastofullclinicalprograms
• Productlicenseorapprovaloftennecessarytovalidateunderlyingtechnology
Challenges
• Difficulttoextractmeaningfulbenefitsorperformancefromolddrugs
• BigPharmacompaniesusuallyeschewnon-NCEproductcandidates
• Reimbursement canbeatremendouschallengewithoutdemonstratedhead-to-headclinicalbenefits
OurSolution
• Prioritizationbasedonlocalcompetitiveenvironments&superioritytogenerics
• Seekpartnersoutside“BigPharma”landscape, suchasAsiaandLatAm
• Focus onclinicalbenefits,nottechnicalperformance
OurExperienceatPenwestRemainsQuiteRelevant
7
![Page 8: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/8.jpg)
Consulting:AnalysesHelpFocusBDEffortsOurApproachHelpsFocusOut-LicensingEffortsOnAssetsWithGreatestChanceofSuccess
8
AssetAnalysis• Indications•Datainhand•CommercialOpportunity•Developmentplan• IP•Competition
PartnerPerspective•Searchforpotentialpartners•Examinetheirrequirements•Assessgapsintheirpipelineorrevenueforecasts
Decision•YES- Assetislicensableandseveralpotentialpartnersidentified
•NO- Noobviousmarketforasset;deprioritize
•MAYBE- Assethaspotential,butgapsexist,i.e.,datagaps &furtheranalysis
Deliverableisareportwhich:• Prioritizesassetstofocusout-licensingefforts• Identifiesprospectivepartnerstotarget• Providesinformationtohelpcustomizemessagetotargetcompany
![Page 9: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/9.jpg)
CaseStudy:License-AbilityandPrioritizationWeHelpFocusLicensingEffortsToMaximizeChancesForATransaction
9
Situation
• Asiangovernmentresearchinstitutewith12drugdiscoveryprograms
• Eachwithalibraryofnoveldrugcandidatesandinitialpreclinicaldata
• Instituteinitiatedout-licensingefforttofindcorporatepartners
Challenges
• Onlyonepersonresponsibleforout-licensing12programs
• SomeNCEswereagainstestablishedtargets,somewithonmarketproducts
• Lackofcleardetailedcommunicationinpresentationmaterials
OurSolution
• Were-prioritized andfocusedeffortson6ofthe12programs
• Repositionedassetstogeographiesoutsideestablishedmarkets
• Workedtoreviseallnon-confidentialandconfidentialdatapackages
![Page 10: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/10.jpg)
BDAudits:WhatHappensWhenBDIsNotSuccessful?
CommercialAssessments– WhatCanGoWrong?• ExaggerationsorincorrectassumptionscanquicklyleadtoBDfailure• Overestimationofreimbursementenvironmentanotherproblem•Wecanidentifyareasthatrequirerevisionofexistingdata
OutreachProcess• Areyouattendingtherightconferences?• Areyoutalkingtotherightpeople?• Areyourmaterialscustomizedforyouraudiences?
BDPersonnel&SkillSet• Doyouneedleadgeneratorswhenyouonlyhaveclosers?• Isthereamismatchbetweenyoursalesfunnelandyourorganization?• Aretherightpeoplewiththerightskillsinplace?
WeCanAuditExistingEfforts,ProvidingReal-WorldAdviceWhichMayLeadToSuperiorResults
10
![Page 11: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/11.jpg)
DatabaseSearchesIdentifyProductsandCompaniesMedTrackIsButOneToolInTheOverallSearchProcess
11
• MedTrack canbeusedtoidentifyindividualtecjnologies,productsandcompanies
• Otherdatabasesusedincludethosefrompastpartneringconferences,partnering360,data.com,andothers
SearchforEarly-StageAssetsandTechnologiesinGastroenterology
![Page 12: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/12.jpg)
ExamplesofPast&CurrentConsultingClientsProjectsInvolvedLicensing,MarketResearch,DueDiligence,&OtherTopics
12
![Page 13: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/13.jpg)
TeamandPartners
![Page 14: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/14.jpg)
LacertaBioLeadership– CarlosN.Velez
14
Nearly20YearsExperienceinConsultingandBusinessDevelopment
14
• FounderandManagingPartnerofLacertaBio (2010)• CurrentandpastclientsincludeTzamal(Israel),Panion(Sweden),Nevakar
(USA),CombiGene(Sweden),Troikaa(India),KRICT(Korea),Cornerstone(USA),Almac(UK),UniversityofBath(UK),APJLabs(India),Pfizer(USA)…
• Co-founderofConnexinTherapeutics,anophthalmologydrugdevelopmentcompanycurrentlyraisingaSeed/SeriesAroundoffinancing.
• PreviouslytheChiefBusinessOfficerofLanticTherapeutics(UK)untilthepassingofthescientificco-founderin2012.
• FormerDirectorofBusinessDevelopmentatPenwestPharmaceuticals,wherehewasresponsiblefortheout-licensingof505(b)(2)programsdevelopedinternally,aswellasthescoutingandanalysisofneurologyin-licensingopportunities.
• OtherpreviousemployersincludeForestLabs,FrankelGroup(nowHuronConsulting)andGenencor(nowownedbyDanisco).
• B.S.inPharmacyfromtheAlbanyCollegeofPharmacy,aPh.D.inPharmacyfromtheUniversityofNorthCarolinaatChapelHill,andanMBAinFinancefromtheRochesterInstituteofTechnology.
![Page 15: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/15.jpg)
OurPartnershipsWePartnerWithExpertsGlobally,OnAPer-ProjectBasis,ImprovingGlobalReachandEfficiency
15
Since2010,London-basedEgamidhasfacilitatedvarioustransactionsacrossEurope,Asia,andNorthAmerica
WithofficesinShanghai,HongKong,andBeijing,LingmedoffersavarietyofpartneringservicesandtoolsfortheAsianmarkets
OperatesdualbusinessmodelofconsultingandcompanyformationfromofficesintheUS,Europe,andChina
![Page 16: Driving Innovation And Strategic Excellence in the Life ...lacertabio.com/wp-content/uploads/2016/12/Lacerta-Bio-Introduction... · opportunities. We source and assess novel technologies,](https://reader036.vdocument.in/reader036/viewer/2022071219/6054ed81e4a323755648f9fd/html5/thumbnails/16.jpg)
DrivingInnovationAndStrategicExcellenceintheLifeSciences
CarlosNVelez,Ph.D.ManagingPartnerLacertaBioInc.
[email protected]+18452933343