DRUG STUDIES

DRUG NAMEDATE

ORDEREDCLASSIFICATION

DOSEROUTE

FREQUENCY

MECHANISM OF ACTION

SPECIFIC INDICATIO

NSIDE EFFECTS

NURSING IMPLICATIONS

CEFTRIAXONE SODIUM

(ROCEPHIN)

8-7-2013 ANTIBIOTIC 2 G IVTT Q12H ANST ( - )

PLS GIVE THRU IV DRIP

Inhibits cell wall synthesis, promoting osmotic instability; usually bactericidal

UTI COMMON S/EDiarrheaRashesPain @ injection site

ADVERSE S/EPseudomembranous ColitisLeukopeniaAnaphylaxis

BEFORE1.Ask patient if he’s allergic to penicillins or cephalosporins2.Obtain specimen for culture and sensitivity tests before giving first dose3.Monitor CBC, renal and liver function tests

DRUG PREPARATION1.Dilute 2 G vial with 19.2 mL of sterile water, NSS, or D5W2.Do not mix or co-administer Ceftriaxone with calcium-containing IV solutions

DURING1.Give over 30 minutes

DRUG NAMEDATE

ORDEREDCLASSIFICATION

DOSEROUTE

FREQUENCY

MECHANISM OF ACTION

SPECIFIC INDICATION

SIDE EFFECTSNURSING

IMPLICATIONS

AFTER1.Tell patient to report discomfort at IV insertion site2.Tell patient to report loose stools or diarrhea

DRUG NAMEDATE

ORDEREDCLASSIFICATION

DOSEROUTE

FREQUENCY

MECHANISM OF ACTION

SPECIFIC INDICATION

SIDE EFFECTSNURSING

IMPLICATIONS

OFLOXACIN(FLOXIN)

8-7-2013 FLUOROQUINOLONE 400 MG TAB1 TAB BID

PO

Interferes with DNA gyrase, which is needed for synthesis of bacterial DNA. Spectrum of action includes many gram-positive and gram-negative aerobic bacteria

COMPLICATED UTI

COMMON S/EDrowsinessDizzinessNauseaVomitingAbdominal pain

ADVERSE S/EPseudomembranous ColitisAnaphylactic reactionLeukopenia

BEFORE1.Obtain specimen for sensitivity and culture test2.Monitor CBC, renal and liver function tests

DURING1.Drug maybe taken with or without regard to meals2.Take each dose with a full glass of water 3.Take the drug 1 hour before or 2 hours after antacids

AFTER1.Avoid sun exposure2.Take antacids 1 hour before or 2 after after Ofloxacin3.Warn patient that dizziness may occur4.Tell patient to stop drug and report @ first sign of allergic reaction

DRUG NAMEDATE

ORDEREDCLASSIFICATION

DOSEROUTE

FREQUENCY

MECHANISM OF ACTION

SPECIFIC INDICATION

SIDE EFFECTS

NURSING IMPLICATIONS

DUTASTERIDE + TAMSULOSIN(DUODART)

8-87-2013 ALPHA ADRENORECEPTOR

ANTAGONIST

500 MG / 400 MG1 TAB OD

PO

Blocks alpha – adrenergic receptors in the prostate. This action inhibits smooth muscle contraction in the prostate, prostatic capsule, prostatic urethra, and bladder neck, which improves the rate of urine flow & reduce symptoms of BPH

TO TREAT BPH COMMON S/EDizzinessDrowsinessOrthostatic HypotensionDiarrhea

BEFORE1.Rule out prostate cancer

DURING1.Take drug 30 min after same meal each day2.Do not open, crush, or chew drug capsules

AFTER1.Change position slowly to minimize effect of orthostatic hypotension2.Avoid hazardous activities until CNS effects are known

DRUG NAMEDATE

ORDEREDCLASSIFICATION

DOSEROUTE

FREQUENCY

MECHANISM OF ACTION

SPECIFIC INDICATION

SIDE EFFECTS

NURSING IMPLICATIONS

LACTULOSE(CEPHULAC)

8-8-2013 LAXATIVE 30 CC QHSPO

HOLD FOR BM GREATER THAN

2X / DAY

Produces an osmotic effect in colon; resulting distention promotes peristalsis. Also decreases ammonia, probably as a result of bacterial degradation, which lowers the pH of colon contents.

CONSTIPATION COMMON S/EAbdominal crampsBelchingDiarrheaFlatulenceGaseous distentionNauseaVomiting

BEFORE1.Assess pattern of bowel movement 2.Monitor serum electrolytes especially sodium and potassium

DURING1.Advise patient to increase water intake at least 2-3 L / day to prevent dehydration2.Avoid using antacids and lactulose together3.Tell patient not to use other laxatives during lactulose therapy

AFTER1.Assess effectiveness of medicine2.Document findings and interventions done

DRUG NAMEDATE

ORDEREDCLASSIFICATION

DOSEROUTE

FREQUENCY

MECHANISM OF ACTION

SPECIFIC INDICATION

SIDE EFFECTS

NURSING IMPLICATIONS

ACETAMINOPHEN(PARACETAMOL)

8-7-2013 ANALGESIC 500 MG TAB1 TAB Q4H PRN

FOR T > 38 C

Thought to produce analgesia by inhibiting prostaglandin & other substances that sensitize pain receptors. Drug may relieve fever through central action in the hypothalamic heat-regulating center

FOR FEVER COMMON S/EDrowsinessNauseaVomitingAbdominal pain

ADVERSE S/ELeukopeniaNeutropeniaHypoglycemiaHemolytic anemia

FOOD-DRUG INTERACTIONSCAFFEINE (Increase analgesic effect)

ALCOHOL (Increase risk of liver damage)

BEFORE1.Monitor body temperature2.Monitor CBC and U/A 3.Monitor LFT

DURING1.Take only as directed and with food or milk to decrease GI upset2.Limit caffeine intake3.Avoid alcohol as this may cause hepatotoxicity

AFTER1.Recheck body temperature after 30 min of administration2.Report any adverse reactions3.Document findings and interventions done

DRUG NAMEDATE

ORDEREDCLASSIFICATION

DOSEROUTE

FREQUENCY

MECHANISM OF ACTION

SPECIFIC INDICATION

SIDE EFFECTS

NURSING IMPLICATIONS

DIOSMIN + HESPERIDIN

(DAFLON)

8-10-2013 MULTIVITAMIN 2 TABS TID X 3 DAYS

AND1 TAB FOR

NEXT SUCCEEDING

DAYSP.O.

Daflon is phlebotonic. It reinforces venous tone by prolonging the activity of parietal nor-adrenaline. Thus, Daflon decreases venous capacitance, venous distensibility, & venous emptying time

ACUTE HEMORRHOIDAL

ATTACKS AND CHRONIC

HEMORRHOIDAL DISEASE

Upset stomachHeadacheNauseaVomitingUnusual taste in mouth

BEFORE1.Note indication for therapy

DURING1.Take with food

AFTER1.Report any adverse reactions2.Document findings and interventions done