_drug_endings-_nclex_.pdf

8
-azosin vin- -dopa -ine -pam -lol -mycin (micin) ceph (cef)

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  • -azosin vin-

    -dopa -ine

    -pam -lol

    -mycin(micin) ceph (cef)

  • antihypertensive alpha1-adrenergic blockers in

    peripheral vasculature use: HTN,BPH adfx: orthostatic hypo tn,

    reflex tachycardia, NasalCongestion, periph edema first

    dose at HS-causes faintinginitially

    Vinca-alkyloid antineoplastic. derivedfrom periwinkle. interferes with cell

    division ex: vinblastine use: CA- affectsevery rapid producing cell in body adfx:CNA Depression, stomatitis, alopecia,

    bone marrow suppression check reflexes,give with Zyloprim to reduce uric acid and

    adfx risk of extravasation. check IV

    antiparkinson. essentiallyreplace dopamine (alsoparlodel) adfx: ataxia,

    anticholinergic, dizziness B6can reverse effects, avoid

    CNS depressants

    beta-adrenergic agonists(bronchodilator, increase vasc

    resist) ex: norepinephrine(Levophed ), dopamine

    (Inotropin) used cardiac arrest,COPD adfx: anticholinergic,

    dysrhythmias

    benzodiazepine adfx:depression, CNS depression,addictive. d/c slowly caffeine

    and nicotine decreaseseffectiveness

    beta blockeradfx:

    bronchospasm

    aminoglycosides-inhibitprotein synthesis gram

    neg adfx:oto andnephrotoxic check cranial

    nerve 8 (ear)

    cephalosporin-tonsillitis,prophylaxis, meningitis-bacterialwall inhibitor adfx: bone marrow

    depression, GI upset, crossallergy w/pcn, protein/glucose in

    urine do not drink etoh, takewith food

  • -floaxcin -thromycin

    -cillin sulf, zulf,bactrim

    -cycline -azine

    -cyclovir -dronate

  • fluoroquinalones- dna inhibitoranthrax tx, e. coli adfx:decreased WBC, hct.

    elevated liver enzymes don'ttake with food

    macrolide-cell membranebinder used in pcn allergy. usedfor dental prophylaxis in valve

    disorders adfx: confusion,increases effects of coumadin,theophylline take without food

    penicillin-inhibits synthesisof cell wall severe

    infx-syphillis, lyme disease...adfx: stomatitis, allergy take

    without food

    sulfonamide-antagonizes folicacid synth UC, crohn's, uri adfx:

    peripheral neuropathy,photosensitive, crystalluria,stomatitis take with food,

    encourage fluids, mouth care

    tetracycline-prevents proteinsynthesis baby eye drops, acne

    adfx: discoloration of primaryteeth in utero or in early

    childhood, phototoxic, toxicwhen expired take without food

    antipsychotic-block dopaminereceptors adfx: akathisia,

    dyskinesia, dystonia,parkinsonian, tardive

    dyskinesia, leukopenia, canstunt growth in kids avoid etoh

    and caffeine

    antiviral, inhibits DNA andRNA (includes non

    -cyclovirs too) use in herpes,HIV adfx: HA, dizziness, GI

    doesn't cure.

    biophosphenates-antiosteoporosis inhibitbone resorption adfx:esophagitis, arthralgia

  • -tropium, -ol,-phylline -zolamide

    -oxin -fate

    -sone -arin

    -etine, -aline-ase

  • bronchodilators uses:COPD,asthma (terbutaline for

    preterm labor) adfx:tachycardia, dysrhythmias,palpitations, anticholinergic

    take bronchodilator first

    anti-glaucoma, decreasesproduction of aqueous humoradfx: blurred vision, lethargy,

    depression, anorexia,decrease potassium

    cardiac glycoside-increase force of myocardialcontraction, slow HR Left heart failure adfx:bradycardias, N/V, visual disturbance hold ifpulse

  • -ylate anti-gout

    -statin -pril

    -lol -ipine

    -artan

  • antidiarrheals (alsoimodium) adfx:anticholinergic,

    constipation cxn inunknown abd pain

    cholsalide (Colchicine), benemid(Probenecid), Zyloprim (Allopurinol)

    decreases uric acid Probenecid increasesaction of Cipro Colchicine used only inacute gout syndrome Probenecid forchronic adfx: agranulocytosis, renal

    calculi-flush kidneys at treatment maytake with food/milk/antacids

    antihyperlipidemia- statins blocksynthesis of cholesterol and

    triglycerides(sequestrans-Questran-blocksabsorption) adfx: constipation,

    fat-soluble vitamin deficiency takehs or at least 30 minutes before

    meals. assess diet cannot take withother meds

    antihypertensives ACEInhibitors-affect

    arteries-vasodilation in wholebody use for HTN and CHF

    adfx: lethargy initially,orthostatic hypotension take

    without food

    antihypertensives beta adrenergicblockers- decreases excitability of

    heart, decreases oxygenconsumption use: angina, SVT,HTN adfx: bronchospasm, HR

    changes take with food, taper off toavoid rebound HTN

    antihypertensives also diltiazem,verapamil calcium channel

    blocker-inhibit calcium influx acrosscell membrane to slow conduction anddilate coronary vessels and decrease

    HR uses: angina, HTN, interstitialcystitis adfx: hypo tn, GI upset SR-do

    not chew, crush, open

    antihypertensives angiotensinII-receptors uses: HTN, heartfailure, MI, neuropathy, strokeprophylaxis adfx: dizziness,GI distress SR-do not chew,

    crush, open