drugs
TRANSCRIPT
Chemical Name/Generic Name
Brand Name
Functional Class Dose, Route, Frequency
Action Indication Contraindication
Side Effects
Nurses Responsibilities
Nurokind
Nervijen750mcg,
Nootropics & Neurotonics/Neurotrophics / Vitamin B-Complex / with C
Oral, sublingual, injection.
NUROKIND PLUS cap: methylcobalamin 1.5 mg, folic acid 1.5 mg, vitamin B1 10 mg, vitamin B6 3 mg, alpha lipoic acid 100 mg.Click
VitB12 deficiency,Peripheral neuropathy,
Hypersensitivity.
Assess for hypersensitivity reactions.
Cortiza
Ecospirin
Aspirin BP 75 mg.
Antiplatelet (inhibitor of platelet aggregation)
Thrombot ic cerebrovascular orcardiovascular disease: 4 tablets ofECOSPRIN 75 daily.After myocardial infarction: 2 tablets ofECOSPRIN 75 daily for one month.Following bypass surgery: One tabletof ECOSPRIN 75 daily
Itinhibits the formation of cyclooxygenaseproducts (Thromboxanes,Prostaglandins, Prostacycl ins) .
Prophylaxis against arterial occlusiveevents : Stroke, myocardial infarction,myocardial reinfarction and afterbypass surgery.
hypersensi tive and gastrointestinal ulceration, last 3 months ofpregnancy.
nausea, dyspepsia,gastrointestinal ulceration, bronchospasmand asthma in hypersensitivepatients
It should be administeredwith caution to patients in asthma,nasal polyps, and allergy. Aspirinpenetrates into breast milk, so itshould
be administered with caution tolactating mother.
Clodrel Clopact 75mg,Clopiget 75mg,). Aclotil
antiplatelet agent (thienopyridine class),
Anticoagulants, & Fibrinolytics (Thrombolytics)
Oral Prophylaxis of thromboembolic disordersAdult: 75 mg once daily.Acute coronary syndrome Adult: For ST-elevation myocardial infarction: In combination with aspirin: 75 mg once daily. Patients ≤75 years old may be given a loading dose of 300 mg. Continue treatment for up to 28 days. For unstable angina, non-ST-elevation myocardial infarction: Initial: 300 mg loading dose, followed by 75 mg once daily (with aspirin 75-325 mg once daily
inhibits the binding of adenosine diphosphate to its platelet receptor and the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation.
Given alone or with other medications for prevention or treatment of stroke and heart attack (which are usually caused by blood clots)
Lactation, hypersensitivity, peptic ulcer or bleeding within the skull
Dyspepsia, abdominal pain, nausea, vomiting, flatulence, constipation, gastritis, gastric and duodenal ulcers. GI upset, diarrhoea, paraesthesia, vertigo, headache, dizziness, pruritus and rashes. Bleeding disorders including GI and intracranial haemorrhage. Blood dyscrasias
Co-admin with NSAIDs may increase the risk of stomach and intestinal bleeding. High-dose clopidogrel may lead to increased warfarin levels thus increasing the risk of
bleeding.
Caution needed for patients at risk of increased
bleeding from trauma, surgery, or other pathological conditions; ulcer; liver and kidney impairment; history of bleeding or haemostatic disorders, pregnancy.*Avoid injury or bruising while taking this medication.*It may
cause dizziness, avoid driving a car or operating machinery, or other unsafe tasks.
Megteol
Dobutamine
Cardiforce Inj, Dobutam , Dobutasys Inj, Dobutrex Vial, Dobutrop Inj, Dotamin Vial,
beta-adrenergic stimulating agent, Ionotropic agent.
Dilute with dextrose 5% in water or normal saline solution to at least 50 ml of solution. Know that drug is incompatible with alkaline solutions, such as sodium bicarbonate injection.
Stimulates beta1-adrenergic receptors of heart, causing a positive inotropic effect that increases myocardial contractility and stroke volume. Also
severe chronic congestive heart failure and to provide adjunct in cardiac surgery.
Idiopathic hypertrophic subaortic stenosis or known hypersensitivity
cardiovascular effects, including tachycardia, hypertension, arrhythmias, and precipitation of angina. Nausea, vomiting, and
Monitor ECG and blood pressure continuously during administration.• Monitor fluid intake and output.
Icidob Vial, Inoject Inj, Kardia Amp.
Route
Onset
Peak
Duration
I.V.1-2 min
10 min
Brief
reduces peripheral vascular resistance, decreases ventricular filling pressure, and promotes atrioventricular conduction
headache may also occur.
.Assess electrolyte levels. Stay especially alert for hypokalemia.
• Instruct patient to report anginal pain, headache, leg cramps, and shortness of breath.• Explain need for close observation and monitoring.• As appropriate, review all other significant and life-threatening adverse reactions
and interactions,
Doxidin
Folipar Folate, Folic acid
VitB Complex group. 400mcg, subcutaneous/iv .8-1mg/day.
Needed for erythropoesis, increases RBC,WBC,platelet formation in megaloblastic anemia.
Megaloblastic or macrocytic anemia caused by folic acid deficiency, hepatic disease, alcoholism, hemolysis, intestinal obstruction.
Hypersensitivity, anemias other than megaloblasstic/ macrocytic anemia, Vit B12 deficiency,, uncorrected perinicious anemia.
Flushing, Bronchospasm
Assess for fat igue, dyspnoea, weakness.
Insulin
Ismo(isosorbide mononitrate)
Imdur®, Ismo®, Monoket®.
Nitrate 20 mg (one tablet) twice daily, with the two doses given 7 hours apart
its nitric oxide metabolite, is direct relaxation of vascular smooth muscle. The result is dilatation of
angina pectoris due to coronary artery disease.
Hypersensitivity. arrhythmias
, atrial
fibrillation,
hypotensio
n,
palpitation
careful clinical or hemo-dynamic monitoring must be used to avoid the hazards
peripheral arteries and veins.
s, postural
hypotensio
n,
premature
ventricular
contraction
s,
supraventri
cular
tachycardi
a, syncope.
pruritus,
ras
h.abdomina
l pain,
diarrhea,
dyspepsia,
tenesmus,
tooth
disorder,
vomiting.
dysuria,
impotence,
of hypotension and tachycardia.
urinary
frequency
.asthenia,
blurred
vision, cold
sweat,
diplopia,
edema,
malaise,
neck
stiffness,
rigors.
arthralgi
a.agitation,
anxiey,
confusion,
dyscoordin
ation,
hypoesthesi
a,
hypokinesia
, increased
appetite,
insomnia,
nervousnes
s,
nightmares
.bronchitis,
pneumonia,
upper-
respiratory
tract
infection
Vit K Phylloquinone; K1; Menaquinone; K2; sMenadione; K3
Nutrients
List
No.
Container
Inj. In
Container
Volume
Concentration
9157
1 mL Ampul
1 mg 0.5 mL
2 mg/mL
9158
1 mL Ampul
10 mg
1 mL
10 mg/mL
Oral-Whenever possible, Vitamin K1 Injection (Phytonadione Injectable Emulsion, USP) should be given by the subcutaneous route. When intravenous administration is considered unavoidable, the
Promotes hepatic formation of active prothrombin(Factor II), proconvertin(factorVII), Plasma thromboplastin component or Christmas
Hypoprothrombinemia (prophylaxis and treatment), hemorrhagic disease of the newborn.
Hepatic function impairment, Glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Flushing, redness, pain or swelling at place of injection, unusual taste.
Assess for bleeding: emesis, stools, urine.PT during treatment , monitor for bleeding,pulse
drug should be injected very slowly, not exceeding 1 mg per minute.
factor(factor IX),stuart factor (factorX), which are essential for normal blood clotting.
and BP.Nutritional status: liver, spinach, coffee, asparagus, cabbage, lettuce, greens.