DZAB Medical Incorporated

Della HasanAmber McCreary Bianca Bullock Zain Bhatti

The Kidney

Why do our Kidney’s Fail?

Kidney failure develops when the kidney

becomes less effective at filtering out waste

products, water and salt from the blood

Figure 1: The Association Between Creatinine and Kidney Function

(This figure plots the amount of kidney function as calculated by the Cockcroft-Gault formula for a 55-year-old white male.)

Statistics and cost • 26 million American adults have CKD and

millions of others are at increased risk

• $44,000 per year per patient spent on Dialysis

• In 2007, Medicare spent $8.6 billion on the treatment and medication of dialysis patients

• Medical cost of kidney transplant averages around $262,900

Mission Statement

We at DZAB are advocates for life. Many doubts surround stem cell research, however in reality it may be

one of the most effective and natural way of curing ,many diseases today. What better way to heal the body than with natural cells that one is ultimately made up of. At DZAB Medical Inc. we are taking medicine and

innovation to the next step in developing the first functional adult size kidney from stem cells.

Stem Cell Research

Types of stem cells

(All stem cells regardless of their source have three general properties: they are capable of dividing and renewing themselves for long periods; they are unspecialized; and they can give rise to specialized cell types.)

Embryonic stem cells

Somatic “Adult” stem cells

Why must we develop an Adult size kidney?

“British scientists have created human kidneys from stem cells …..They are currently half a centimetre in length - the same size as kidneys found in an unborn baby”-The Telegraph

Properties of our Kidney

Courtesy of Dr. Narayan Bhattarai, Ph.D. (Assistant ProfessorChemical, Biological and Bioengineering)

The transplant

• Biocompatibility

• Medical advances

• Before

Post-surgery treatment and maintenance Post-surgical treatment would be the same as any other

surgery involving a transplant: Post-surgery treatment after heart bypass

Sixteen of the patients were infused with stem cells Fourteen patients showed the heart pumped efficiency

from 30%-40% after 100 days To maintain any transplant one must

Reduce or avoid stress Avoid sugar rich food Avoid tobacco and alcoholIn order to keep the body healthy, and prevent any further

complications

Natural kidney’s vs. stem celled kidney

Developing a kidney from stem cells allows it to has the same functions as any kidney that a healthy person possess.

Nephron Renal vein Renal artery Renal medulla Renal vein Interlobular artery and vein Nephron Tubules Ureter Renal cortex Renal pelvis Arcuate artery and vein

Work cited http://EzineArticles.com/1342892 http://

www.dailymail.co.uk/health/article-1376044/Human-kidneys-created-stem-cells-organ-breakthrough.html#ixzz1snhqRnTn

http://www.kidney.org/kidneydisease/aboutckd.cfm#facts http

://www.transplantliving.org/before-the-transplant/financing-a-transplant/the-costs/

 http://kidney.niddk.nih.gov/KUDiseases/pubs/kustats/index.aspx  http://www.sciencedirect.com/science/article/pii/

S1369702104002330 http://www.nanowerk.com/spotlight/spotid=8030.php http://healthland.time.com/2011/11/14/first-human-heart-ste

m-cell-trial-shows-promise/#ixzz1tCUk4k00 http://www.stemcellmd.org/guidelines-for-a-stem-cell-patient/