early warning system for respiratory compromise...in the case of potential deterioration: ... otc...
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![Page 1: Early Warning System for Respiratory Compromise...in the case of potential deterioration: ... OTC and professional markets worldwide. Ofer Leizerovich Software Founder & Co-CEO BDR](https://reader033.vdocument.in/reader033/viewer/2022051919/600c587bb0dd5b56cb0ba666/html5/thumbnails/1.jpg)
Early Warning
System for
Respiratory Compromise
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Investors / April 2020
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B r e a t h e V i s i o n
Respiratory compromise
can lead to death
Respiratory compromise is a
progressive condition, occurring
when a patient is unable to
breathe adequately, and it can
lead to respiratory failure or death.
There’s no adequate
early warning signal for
RC today.
And for Corona Patients –
no Predictive Alert
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B r e a t h e V i s i o n
SafeSed offers Remote
contactless, continuous
monitoring of patient
breathing
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The system provides early warning
in the case of potential deterioration:
✓ Reduces the incidence of
respiratory compromise in
multiple clinical settings
✓ Huge near-term opportunities
in remote monitoring of
Corona patients’ condition
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B r e a t h e V i s i o n
Our achievements. Only 18 months to launch
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Operational solution
2 patentsgranted and 3 pending
Clinicaltrials
2 completed; Corona
study to start.
3 IIA plans approved
510(K) pre-
submissioncompleted
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B r e a t h e V i s i o n
Entrepreneurs, management & engineering
experience
Ditza Auerbach Founder &
Inventor
Physicist experienced
in leading imaging and
machine learning R&D
at Aspect Imaging and
Applied Materials.
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Menashe TeremCEO
Led several medical
device companies into
OTC and professional
markets worldwide.
Ofer LeizerovichSoftware
Founder & Co-CEO BDR
Technologies,
25 years of experience
in leading development
of Medical and Cosmetic
Devices.
Ziv GevaEngineering &
Manufacturing
Founder & Co-CEO of BDR
Technologies,
25 years of engineering
management in the medical
and cosmetic fields.
Isaac Levy Financials,
Leading Angel
Over 30 years of
experience in fund
raising and multi-
national contracts
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B r e a t h e V i s i o n
RCis a top 5
most rapidly increasing
hospital costs
$37 billion in annual
costs with no
innovation
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B r e a t h e V i s i o n
A burden on all stakeholders
1 in 8 elective surgery patients and 1 in 14 medical patients suffer from RC
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46,456
19,885
Respiratory FailureCases
Matched Controls
RC associated hospital costs
14.7%
0.1%
Respiratory FailureCases
Matched Controls
RC associated mortality
RC associated
length of stay
21
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Respiratory FailureCases
Matched Controls
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B r e a t h e V i s i o n
Failure
Arrest
Risk
Compromise
Early detection is key
8 * Lee et al., Anesthesiology 2015
97% of the adverse events could be prevented by continuous monitoring of breathing*
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B r e a t h e V i s i o n
SafeSed makes sure you breathe easy
SafeSed reduces the incidence of respiratory compromise by continuously monitoring patients.
Two sensors attached to a patient provide
close monitoring of all vital breathing
information remotely, allowing for immediate
intervention, enabling implementation in
multiple clinical settings.
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Respiratory compromise is a
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B r e a t h e V i s i o n
Continuous, Uninterrupted Breathing Monitoring.
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A true continuous monitor that is actionable
Wireless/tubeless
communication
Low cost sensor. Setup within seconds
Reusable sensor
Disposable patch
Technology embedded
in multi-channel monitor
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B r e a t h e V i s i o n
Strategy: Embed SafeSed in Vital Sign Monitors
Creating the
most
comprehensive
patient monitor
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B r e a t h e V i s i o n
Standard breathing indicators. All the time.
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Alerts for
➢ High and low respiratory rates
➢ Shallow breathing
➢ Paradoxical breathing/
Obstructed Airway
➢ Breathing depth trends
Measures
what counts➤ Accurate respiratory rate -
number of breaths per
minute
➤ Breathing volume trend -
amount of air moved with
each breath
➤ Number of Apnea/Hypopnea
events
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B r e a t h e V i s i o n
Technology based on machine learning
Sensors
Simple application of 2 wearable inertial
sensors are placed on the patient’s abdomen
and chest
Continuous monitoring
Breathing parameters based on machine
learning: respiratory rate, breathing depths, apnea and obstructive
breathing
Alerts
Nurse is alerted in the event the patient
deteriorates.
Use of big data analysis improves the quality
and accuracy of alerts over time
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B r e a t h e V i s i o n
The solution: Continuous monitoringUninterrupted monitoring of vital signs could reduce and prevent respiratory compromise
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Nurse –Manual
➤ Burden on staff leaves
patients unmonitored for
96% of the time
➤ Inaccurate spot-check
entries may not represent
the patient’s true
condition
Capnography – continuous
➤ Measures CO2 in exhaled breath
➤ “Noisy” on spontaneously
breathing patients (open
system)
➤ High costs (system/consumable)
➤ Uncomfortable tubes
Pulse Oximetry –continuous
➤ Widely used
➤ Inexpensive
➤ Alerts are too late for
timely interventions
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B r e a t h e V i s i o n
The Corona Effect: Governments and Healthcare providers switched all resources to Early prediction of breathing
deterioration in Coronavirus Patients
15 * Lee et al., Anesthesiology 2015
Coronavirus: An infection disease that affects the lungsContinuous remote monitoring is needed to
detect early signs of patient deterioration who
may require ventilator support.
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B r e a t h e V i s i o n
Corona pilot to start at three leading medical centers in
Israel
SafeSed will remotely monitor Corona
patients reducing the risk of exposure to
medical teams and offering early warning
to potential patient deterioration.
The pilot opens huge opportunities for
all hospitals in need of remote
monitoring of breathing
worldwide
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B r e a t h e V i s i o n
SafeSed is implementable in multiple markets
3 yearsICU/General
Floor
5 yearsHome use:
sleep apnea, COPD, infants
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Quick
LaunchCorona Patients
2 yearsDuring deep& moderate
sedation procedures
Post-operation recovery room
1 year
הכל זז שנה קדימה–עודכן
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B r e a t h e V i s i o n
Unique solutions. Unparalleled opportunity.
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$37bn - Overall burden of RC. Near-term opportunities in Corona
Capnography – The only solution today. Noisy and expensive
SafeSed - Shown to accurately monitor breathing continuously
Clear roadmap to market – Regulatory and business model
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Let’s work together to dramatically reduce respiratory compromise
Website: www.breathevision.comMenashe Terem (CEO): [email protected] Auerbach (CTO): [email protected]
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