economic impacts attributed to aflatoxin

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    Economic ImpactsEconomic ImpactsAttributed toAttributed to

    AflatoxinAflatoxin

    Dr.Kedar KarkiDr.Kedar Karki

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    What is Aflatoxin?What is Aflatoxin?

    Aflatoxin refers to a group of extremely poisonousmycotoxins produced by two common fungi,Aspergillusflavus andAspergillus parasiticus. These toxins are namedfor a fungus that produces them, e.g. A from the genusnameAspergillus, fla from the species name flavus addedto toxin to give the name aflatoxin. Mycotoxins are

    chemical compounds produced by fungi while growing onorganic substances such as corn, peanuts, or cottonseed.When these compounds are consumed by animals orhumans, they may produce severe undesirable healtheffects.

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    What is Aflatoxin?What is Aflatoxin?

    Although it has been known for over 100 yearsthat moldy grains consumed by animals orhumans could cause serious illnesses, it was notuntil 1961 that scientists proved that the death of

    over 100,000 turkey poults was caused byconsumption of aflatoxin-contaminated grain.Beginning in the 1960's, intensive study ofaflatoxin and the illnesses it causes has welldocumented that serious health effects can occur

    when aflatoxin-contaminated feed or food areconsumed.

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    AflatoxicosisAflatoxicosis

    Beef Cattle:

    Early indications of aflatoxin toxicity includereduced feed intake followed by reduced weight

    gain or weight loss. Often there is reduced feedefficiency, increased susceptibility to stress, anddecreased reproductive performance. Chronicaflatoxicosis is characterized by unthriftiness,anorexia, prolapse of the rectum, liver and kidney

    damage, depression of the immune system, andedema in the abdominal cavity.

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    PoultryPoultry

    Aflatoxin affects all poultry species. Youngpoultry, especially ducks and turkeys, arevery susceptible to aflatoxicosis.Generally, immature, growing poultryshould not receive more than 20 ppbaflatoxin in the diet. However, feedinglevels lower than 20 ppb may still reduce

    their resistance to disease, decrease theirability to withstand stress and bruising,and generally make them unthrifty.

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    PoultryPoultry

    Laying hens usually can toleratehigher levels of aflatoxin than youngbirds, but aflatoxin levels still should

    be less than 100 ppb. Aflatoxicosiscan reduce the birds ability totolerate stress and other diseases byinhibiting the natural immune

    system.

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    PoultryPoultry

    Stunted growth, increased mortality,reduced egg size and production, liver andkidney disorders, leg and bone problems,suppression of the immune system withincreased susceptibility to infections suchas Salmonella are common symptoms ofaflatoxicosis in poultry. Decreased bloodclotting results in greater downgrading

    and rejection of birds due to massivebleeding and bruises.

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    SwineSwine

    Swine are sensitive to aflatoxin, especially nursing ornursery-age swine. Generally, aflatoxin consumptionprimarily causes liver damage and can result in reductionsin feed intake and growth performance. Aflatoxin levels of100 to 400 ppb cause reduced growth rate and lower feed

    efficiency. This level of aflatoxin affects breeding stock,unweaned nursery, and growing pigs more than finishingswine (greater than 100 pounds). It is extremely importantto keep toxin exposure to breeding swine to a minimum.Aflatoxin levels of 400 to 800 ppb has caused liver damage,bleeding disorders, immune system suppression, abortions,and death.

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    Producer CostsProducer Costs

    Crops:

    Yield loss

    Restricted markets Nonmarketable product Price discounts Increase product costs Increased post-harvest costs

    Difficulty obtaining loans on stored grain Disposal of useless crops Monitoring and sampling

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    Processor CostsProcessor Costs

    Restricted markets

    Loss of markets

    Reduced demand

    Product loss Insurance premiums

    Litigation costs

    Monitoring and testing

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    Livestock and Dairy:Livestock and Dairy:

    Higher mortality rates

    Reproductive failures (abortions)

    Reduced feed efficiency

    Higher feed costs

    Lower live weight

    Reduced disease immunity

    Overall quality loss

    Lower milk production

    Unmarketable milk

    Monitoring and testing

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    Consumer CostsConsumer Costs

    Less nutritious food

    Higher product prices

    Possible health problems

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    Social CostsSocial Costs

    Regulatory costs

    Research and education

    Lower foreign exchange earnings Increased costs of imports.

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    Handler / DistributorHandler / DistributorCostsCosts

    Extra drying costs

    Excess storage capacity Losses in transit

    Loss of markets

    Monitoring and testing

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    HandlingHandlingAflatoxin Contaminated GrainAflatoxin Contaminated Grain

    Crop Destruction in the Field:

    Crop destruction in the field may beappropriate if aflatoxin levels exceed the

    maximum allowed for any use or forremedial blending or ammoniationprocesses. Aflatoxin levels of 1000 ppb orabove leave few or no alternatives. Crop

    insurance may cover crop destruction if apre-harvest analysis clearly demonstratedthe excessive aflatoxin condition

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    Selective Feeding:Selective Feeding:

    Adult animals generally are moretolerant of aflatoxin than youngeranimals. Animal species differ in their

    sensitivity to aflatoxin consumption.

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    Screening the Grain:Screening the Grain: Various gravity table and shaker screening

    devices exist which can significantly lower theaflatoxin levels in a lot of grain by effectivelyremoving light weight and broken grain which

    often contain high levels of aflatoxin. Grain withlow to moderate levels of aflatoxin contaminationmay be cleaned to meet desired use levels.However, in some cases significant amounts oflight weight and broken grain may be removed,

    and thus reduce the total grain volume.

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    Feed Additives:Feed Additives: Several feed additives as anti-caking agents have shown

    some promise in research tests as aflatoxin-binding agentswhich inhibit the ability of the aflatoxin to be absorbed inthe animals gut. Bentonite clay and hydrated sodiumcalcium aluminosilicate (HSCAS) added to feed have beenshown to decrease the effect of aflatoxin fed to swine and

    poultry. The HSCAS product NovaSil was shown to beeffective at 10 pounds of compound per ton of aflatoxin-contaminated feed at a minimal cost. The bentonite clayproduct Volclay has also been shown to be effective whenadded at the rate of 10 pounds per ton of feed.