Syllabus Dept. Electrical & Computing Engineering:1/2

EE6913: Advanced Biomedical Instrumentation DFL, 2008

1. THE ORIGINS OF BIOPOTENTIALS (4 hours)

Lecture 1: The cell membrane & ionic potentials

Lecture 2: The propagation of nerve action potentials

Lecture 3: The electromyogram (EMG) – signals from muscles

Lecture 4: The electrocardiogram (ECG) – signals from the heart

2. BIOPOTENTIAL ELECTRODES (6 hours)

Lecture 5: The electrode-electrolyte interface

Lecture 6: Half-cell potential variability & polarization

Lecture 7: The Ag-AgCl electrode and its properties

Lecture 8: Electrical models of the electrode-electrolyte interface

Lecture 9: Influence of the skin & artifact generation

Lecture 10: Types of electrodes for clinical & research purposes

3. DIFFERENTIAL AMPLIFIER DESIGN (8 hours)

Lecture 11: The single op-amp differential amplifier – a review

Lecture 12: The two op-amp approach

Lecture 13: Classic instrumentation amplifier (IA) & practical implementations

Lecture 14: High CMRR without resistor matching - a new approach

Lecture 15: The discrete BJT instrumentation amplifier & circuit modeling

Lecture 16: Alternative current mode IA techniques

Lecture 17: Improving CMRR by guarding & bootstrapping

Lecture 18: Accommodating electrode offset potentials

4. COUPLING TO THE ENVIRONMENT (6 hours)

Lecture 19: Line-borne interference

Lecture 20: Effects of electric current on the body

Lecture 21: Microshock & patient safety considerations

Lecture 22: The driven right leg circuit

Lecture 23: Medical electrical equipment standards

Lecture 24: Testing of medical equipment

EE6913: Advanced Biomedical Instrumentation

Course organizer: D. F. Lovely, Rm. 204

Last update: May, 2008

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Syllabus Dept. Electrical & Computing Engineering:2/2

EE6913: Advanced Biomedical Instrumentation DFL, 2008

5. ISOLATION DESIGN TECHNIQUES (5 hours)

Lecture 25: Optical coupling

Lecture 26: Isolation amplifiers using optical techniques

Lecture 27: Magnetic coupling

Lecture 28: Providing isolated power to the instrumentation

Lecture 29: Isolation using capacitors & multi-channel systems

6. LOW NOISE INSTRUMENTATION (5 hours)

Lecture 30: Thermal & shot noise

Lecture 31: Additional sources of internal noise

Lecture 32: Noise models of simple passive components

Lecture 33: Noise modeling of active devices & op-amps

Lecture 34: Noise figure & noise matching

TOTAL LECTURES: 34 hours

LABORATORY EXERCISES TO BE SELECTED FROM:

1. Response time – eye-hand coordination

2. Estimation of electrode model parameters

3. Differential amplifier CMRR

4. Discrete instrumentation amplifier design

5. Common-mode interference in biopotential measurements

6. Driven right-leg amplifier

7. Transformer isolation & flyback modulation

8. Low-noise optical pulse sensor design