effect of mycotoxin in animal health & production

8/14/2019 EFFECT OF MYCOTOXIN IN ANIMAL HEALTH & PRODUCTION

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EFFECT OF MYCOTOXIN IN

ANIMAL HEALTH &

PRODUCTION

ITS

PREVENTION AND

TREATMENT

Dr.Kedar Karki


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MYCOTOXI COSIS

MANIFESTATIONOFMYCOTOXIN POISONING

ACUTE CAUSE OF POOR

ANIMAL PERFORMENCE.


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CHRONIC SUBCLINICAL MYCOTOXIN

INCREASED DISEASESUSCEPTABILITY

POORPERMENCE DIRECT EFFECTION ANIMAL

INDIRECT EFFECT OFIMMUNE SYSTEM.


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CONT.

MOLD AND MYCOTOXIN

WIDELY DISTRIBUTED IN NATURE.

SUFFICIENT ORGANIC MATTER.

WATER, TEMPERATURE TOREPRODUCE.


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CONTD:

LARGE VOLUME OF FEED STUFFSTORED

CONSIDEREBLE OPPERTUNITY FORFUNGAL GROWTH.

FUNGUS CAN PRODUCE MYCOTOXINWHEN IN UNDER STREESS.

MYCOTOXIN INGESTED IN LARGEVOLUME SINGLE DOSE.


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CONTD:

SMALL QUANTITY OVERLONG PERIOS.

ADVERS EFFECT ON PRODUCTIVE CAPACITY

REPRODUCTIVE EFFECIENCY HEALTH OF ANIMAL


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IS THERE A PROBLEM ?

DIFFICULT TO MAKEDIAGNOSIS OF MYCOTOXI

COSIS. SEVERAL GENERAL SYMPTOMS.

SYMPTOMATIC TO OTHERPROBLEM.


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CONTD.

CONSUMPTION OF LESS DRYMATTER

SYMPTOM OF AFLATIOOXIN OROTHER MYCOTOXIN.

MORE INTAKE THAN PRODUCTION

WARRANTS

INDICATES


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CONTE.

DON DIXYNIVALENOL ORZERALENONE.

HIGH INCIDENCE OF DIGESTIVEUPSET.

DIARRHEA, IMPACTIONS.

RUMENSTASIS. LOT OF MUCUS IN DUNG.

SYMPTOMATIC OF ALL MYCOTOXIN.


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CONTE..

HIGH INCIDENCE OF DISEASEASSOCIATED

DEPRESSED IMMUNE SYSTEMS. Eg.H.S.

TISSUE EDEMA GENERELIZED.

BRISKET AND HOCK AREAS.


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SWOLLING AND SLOUGHING OFSKIN

TAIL, ABOVE CORONET. EAR TIPS,NOZZLE

INDICATES MYCOTOXIN

ASSOCIATED WITH

MYCOTOXIN WITH FUSARIUMTYPE.


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HIGH RESORPTION RATE

SHORT HEATS

NYMPHOMANIA

INDICATE ZERALENONECONTAMINATION


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GENERAL UNTHRIFTYNESSAPPEARENCE.

LOWER MILK PRODUCTION

ROUGH HAIR COAT

SAD APPEARENCE


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SLIGHTLY ARCH BACK

DONOT RESPONDS TO RATIONALTREATMENT

SUGGESTIVE OF POOR MANAGEMENT GENERAL CONSIDERATION

FOR FUNGUS GROWTH TO OCCURE.

FOURCONDITION MUST EXISTS.

AN ADEQUATE FOOD SOURCE.

TEMP BETWEEN 31-34o c


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FUNGUS PRODUCES MYCOTOXIN.

IN RESPONSE TO STRESS.

FUNGUS DONOT BE ABLE TOPRODUCE MYCOTOXIN.

SUBJECTEDTO FREEZINGTEMPERATUE.

MOISTURE DEPRIVATION.


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MYCOTOXIN PROBLEM MOREPRONOUNCED.

CROPS GROWING UNDER COOLMOIST CONDITION.

UNDER DROUGHT STRESSEDCONDITION.

DIRECT PROPOTION TO DURATIONOF STRESS.


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400 MYCOTOXIN BUTUNIDENTIFIED.

PURE MYCOTOXIN LITTLE IMPACT. CONJUGATION OF GROOP OF

MYCOTOXIN.

DEVASTATING EFFECT. ON

HEALTH AND PRODUCTIVITY.


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SYMPTOMS

POOR MILK PRODUCTION.

POOR FEED CONSUMPTION.

POOR VODY CONDITION.

DIARRHEA.


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QUANTITIS OF MUCOUS INDUNG

ANESTRUS

POOR REPROSUCTIVE

PERFORMENCE ABORTION


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DRYING ND SLOUGHING OF TAIL ATMANE REGEION.

SWELLING, CRACKING,SLOUGH OFKIN OBOVE HOOF

DRYING, SLOUGHINY CURLING OFEARTIPS.

DRYING AND LOUGHING OFMUZZOL.


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HIGH DISEASE INCIDENCE

GENERAL LETHARGY.

INDICATES EITHER POOR VET.OR MANAGER.


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ACCUMULATE IN LIVER.

LIVER TOXICOSIS.

INCREASE LIVER ENZYMES.

SGOT (SERUM GLUTAMIC ACIL

OXALTE TRANSAMINASE). LDH (LACTICDEHYDROGENASE).


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INCREASD SERUMCHOLESTROLLEVEL

DECREASED WHITE CELL COUNT.

ELASTIN ELASTASE

COLAGENE COLA GENASE.


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HEPATIC CARCINOMA

SPLEENO MEGALY.

LUNG EMPHYSOEMA.

TOXIC TO RUMEN BACTARIA.


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MALABSORPTION OF NUTRIENT.

EXCESSIVE MUCOUS PRODUCTION.

TISSUE EROSION.

HEMORHAGE


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TISSUE NECROSIS

INITIAL IWCREASE OF LYMHOCYTE,NUTRPHIL, MONOCYTE

AFTER THIRD WEEK LYMHICTE TEND TODECLINE

OTHER TWO CELL CONTINEW TOINCREASE

INDICATE THE CHRONICITY OF DISEASE.


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TESTING:

ALL FEED CONTAINS SOME MYCOTOXINS.

NATURAL SITUATION

5 PPB OF ZEAR LENONE WHY TO WORRY

50 PPB 100 PPB IS DANGEROUS.


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SAMPLING OF FEED ANDFORAGE:

FROM BEGINNING

MIDDLE

END

ABSENCE OF ONE MYCOTOXIN DOSE NOT

MEAN

ABSENCE O ALL MYCOTOXIN.


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LOSS OF LIVER FUNCTION.

ULTIMATELY DEATH:


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DEOXYNIVANOLENOL (DON):

mycotxin OF FUSARIUM.

MARKER MYCOTOXIN.


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ZEARALENONE:

ESTERO GENIC ACTIVITY

TWINE OF FUSARIUM.

LOWERED MILK PRODUCTION

ABORTION


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CONTE..

SHORT HEAT CYCLE.

NYMPHO MANIA.


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T2 TOXIN(TRICHOTHECENES):

secondary mycotoxinOF FUSARIUM.

LOWER MILK PRODUCTION

DIARRHEA.


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HEMORRHAGIC BOWEL

STERLITY

IMMUNE FUNCTION SEVERELYDEPESSED

ACUTE DEATH.


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FUMOSINE.

LIVER KIDNEY DAMAGE.

DECREASED IMMUNE SYSTEM.

CARCINO GENIC FOR SWINE HORSE.


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ORCHATOXIN:

Mycotoxins of ASPERGILLUSOCHCEUS.

CONTROLLED STUDY IN ANIMALLACKING ?


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DIAGNOSIS:

CULTURE IN

PDS. NOBUL, SABRODS DEXTROSAGAR

SEROLOY. DOUBLE IMMUNE ASSAYKITS


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MYCOTOXIN IS THE PROBLEWHAT IS THE SOLUTION ?

SaiLAGE TREAT WITH PROPIONICACID.

USE MYCOTOXIN BINDER

IF NOT HERE IS ANTIDEGNALALIQUOR.


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SUPPLIMENT VIT. A AND E

IMMUNO MODULATOR, ADATOGEN,LIVERTONIC IMMUNI STIMULENTS.


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CLINICAL IEATURE OF FUSRIUM MYCOTOXICOSIS IN BUFFALO


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OBSERVATION OF FORAGE

AND FODDER FORFUSARIUM INFECTION


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ANTI DEGNALA LIQUOR

WHAT IS ITS PROPERTIES ?

ALTERATIVE

TONIC

SKIN AND NERVINE TONIC


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ANTI DEGNALA LIQUOR

HAEMATINIC.

STOMACHIC.

ANTHELMINTIC (FOR CERTAIN

PROTOZOA).


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ANTI DEGNALA LIQUOR

CAUSTIC.

PARACITICIDE.

REDUCES OXIDATION.

ACCELARATE FAT DEPOSITION.

HELP TO REMOVE MYCOTXIN BYDIURATION.

THANKS TO


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THANKS TO

ALL PARTICIPANTS


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SHARE WITH ME YOUR IDEA.


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THE END

effect of mycotoxin in animal health & production

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