EFFECTS WORKING GROUPTom Hinton; IRSN; France

• Dose – Effect Modelling to assist Risk Assessments

• Mathematical Derivation of Screening Level Values / Protection Thresholds

• Reach Consensus; Document Methods; Publish Guidance

BROAD OBJECTIVES

EFFECTS GROUP

Australia 1

Belgium 2

Canada 2

France 3

Germany 1

Japan 2

Netherlands 1

Norway 1

Russia 2

Spain 1

Sweden 3

UK 2

21

Active Participants

EFFECTS GROUP

1) UPDATE Dose-Effect DATABASE (11; A. Real; Spain; July ‘09)( UNSCEAR; post 2006; Russian/Ukrainian)

2) DOSE – RESPONSE Relationships (13; J. G-L; IRSN; July ’11; PROTECT)Species Sensitivity Distributions (acute vs chronic; field- vs lab-derived; at various taxonomic levels)

3) Incorporate POPULATION MODELS (9; T. Sazykina; Russia; Jan. ‘11)(Review existing models; life history data; data analyses)

4) Alternative Approaches (9; T. Sazykina; Russia; Jan. ’11; ICRP comm. 5)(will non-parametric and Bayesian methods produce screening levels similar to SSD?)

Outline of Working Plan

EFFECTS GROUP

6) Canadian Benthic Data (4; S. Mihok; Canada; July ‘09)(Uranium mining; derive dose to benthos; multivariate stats)

5) Multiples Stressors (13; H. Vandenhove; Belgium; Dec. ’10; IUR)(Review literature; chemical industry; report on applicability to IAEA; collaborative exp.)

7) Develop and Publish Guidance Documents (21; T. Hinton; France; July. ‘11)(Documentation of methods to derive screening levels; guidance on use of screening

levels; guidance in conducting effects type research)

8) Final Reports to IAEA (21; T. Hinton; France; Jan. ‘12)

Outline of Working Plan

EFFECTS GROUP

Next Meeting

June or July of 2009; Monaco or Vienna;with BIOTA Working Group