EHRA Essentials4U European Heart Rhythm Association (EHRA) – A registered branch of the ESC

Contents

1. The Project ................................................................................................................................................ 2

2. Objectives .................................................................................................................................................. 2

3. Structure .................................................................................................................................................... 3

4. Target Audience ....................................................................................................................................... 3

5. Schedule for Development ................................................................................................................... 3

6. Promotion .................................................................................................................................................. 4

7. Industry Essentials .................................................................................................................................. 4

Annexe 1: EHRA Essentials4U Preliminary Mock-up ............................................................................. 5

Annexe 2: EHRA Essentials4U Preliminary Programme ....................................................................... 6

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1. The Project

In line with the EHRA’s mission and following the very sensitive COVID-19 situation, the objective of this project is to make time sensitive scientific resources (publications, slides, e-Abstracts) available for consultation online to all healthcare professionals1. In this sense, a platform called EHRA Essentials4U will be launched from 9 April 2020, on which new scientific content will be posted every week and made available for a period of three months before being restricted to EHRA members, and without any restriction for a period of 1 year for Industry Essentials content (MyESC account is required to access resources). This platform will become THE comprehensive hub for all scientific content related to heart rhythm disturbances and clinical management.

The EHRA Essentials4U platform will gather the following content online:

1. Late Breaking Trials 2. EHRA Consensus Documents 3. Publications (e-Abstracts) 4. Industry Essentials (latest resources from industry partners in the field) 5. Any other scientific content identified by the EHRA Scientific committee from 9 April to 9

July Other sections will be added online related to the content published such as:

• News articles related to Late Breaking Science

• Link to online Abstract Supplement of the European Heart Journal – EP Europace (available in early June 2020)

• Social Media Wall

• Press articles The platform will be optimised for (computer and mobile devices), with VOD content available at: www.escardio.org/EHRAessentials4U

2. Objectives

The main objectives of EHRA Essentials4U are to:

• Provide HCPs worldwide with access to scientific resources from any region of the globe (in order to fulfil the ESC’s and EHRA’s mission to reduce the burden of cardiovascular disease)

• Keep the community tuned in during the COVID-19 outbreak: content will be offered as a Stop and Watch resource to HCPs to take a break from the day-to-day realities of tackling COVID-19.

• Update heart rhythm professionals on the latest scientific content in the field of EP and arrhythmias

• Reach out to a wider scope of doctors/participants through free access • Allow doctors to watch scientific content at any time of the day (VOD) as they are added

online via ESC/EHRA Essentials4U web pages weekly • Offer industry partners the opportunity to actively participate in this special scientific platform

by sending their own Industry content to be hosted on the dedicated EHRA Essentials4U platform

1 HealthCare Professionals (HCPs). The target audience will be all the HCPs interested in arrhythmias, atrial fibrillation, syncope, device therapies and all other heart rhythm related topic, as well as those who participate in the previous EHRA Congresses.

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3. Structure

• Scientific Committee Structure 2018-2020

▪ Chairperson: Professor Haran Burri & Katja Zeppenfeld ▪ The EHRA Scientific committee has appointed 2 coordinators who will approve the

programme outline ▪ All resources will have to be validated upfront by the EHRA Scientific committee. The

following information will be requested: Title of the session, titles of the presentations, name of the speakers, learning objectives.

• Calendar

The EHRA Essentials4U webpage is due to be launched on Thursday 9 April 2020. New scientific content will be added online on a weekly basis upon reception from contributors.

• Format 3 types of formats can be submitted:

• PowerPoint file • Video including speaker voice over and slides (MP4) • Video created from several PowerPoint files with voice over (MP4)

Multiple presentations can be submitted for a single session. We recommend that the format of the content should not exceed 45 minutes for optimal use on the web. Content must be in English. Industry Essentials will be uploaded within 24 hours (working days) upon reception.

4. Target Audience

EHRA Essentials4U is designed for:

• Cardiologists

• Cardiologists in training

• Fellows in the field of electrophysiology and cardiac pacing

• Electrophysiologists

The target audience will be all the above-mentioned HealthCare Professionals that are interested in arrhythmias, atrial fibrillation, syncope, device therapies and all other heart rhythm related topic, as well as those who participate in EHRA Congress.

5. Schedule for Development

➢ EHRA Essentials4U will launch on 9 April 2020 ➢ Industry Essentials published online on a weekly basis until 9 July (with possibility for Industry to

recommend a date for publication particularly in case of embargo issues) ➢ Industry Essentials available online for 1-year duration on EHRA Essentials4U

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6. Promotion

• Feature in EHRA news bulletins – Cardiac Rhythm: Events, Science & Education – sent to all subscribers – interested in Arrhythmias, Atrial Fibrillation etc – sent to 41 000 subscribers

• Feature in some of the EHRA quarterly Newsletters – sent to current EHRA members (3 200+)

• Feature in some of My ESC weekly Newsletters – sent to 67 000 subscribers

• Feature in some of ESC NCS monthly President letters – sent to all NCS Presidents of 56 ESC National Cardiac Societies (NCS) representing 70 pax

• Dedicated webpage on ESC website hosted on the EHRA homepage section

• Active Social media promotion on ESC accounts in Twitter (#EHRAessentials4U), Facebook & LinkedIn (dedicated campaigns)

• Google AdWords daily campaigns

7. Industry Essentials

Industry Partners are invited to contribute their cutting-edge science to our dedicated platform by providing their ready-made resources of their session(s) as follows:

• Industry Essentials represent a session that can be sequenced in several presentations E.g. 4x15 mins or 4 x 10 mins or 3 x20 mins... (see 3. Format for resource types)

• Industry Essentials are only available for hot topics/late-breaking science, providing a new perspective related to innovations or findings (subject to EHRA Scientific Committee approval)

• Recording is hosted on EHRA Essentials4U webpage for 12 months

Price per session: €10,000 Benefits: Industry Essentials sponsors are entitled to the following benefits:

• Full report including VOD statistics and viewership insights (subject to availability in MyESC accounts) will be sent to the sponsor(s) 3, 6 months and 12 months post publication online

• Platform will be promoted to targeted audiences (see 6. Promotion Plan)

• Opportunity for sponsor to promote the platform and their related content on the platform.

• Questions and Answers (Q&A) form: A Q&A form will be available next to the Industry Essentials resources in order to collect all questions from the audience. Sponsors will be able to post their answers at a later date.

Order Process: Contact your Account Manager or industry@escardio.org to apply for your Industry Essentials session

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Annexe 1: EHRA Essentials4U Preliminary Mock-up

Please note that the below mock-ups are preliminary.

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Annexe 2: EHRA Essentials4U Preliminary Programme

Below is the list of content identified as of 30/03/2020 to be published on this project. This content is still preliminary and is subject to change.

The scientific committee will continue to select new content to post online from 9 April - 9 July. The content will be published gradually on a weekly basis in order to bring new content to the scientific community every week.

a. Late Breaking Trials:

The list below gathers all Late Breaking Trials whose Principal Investigators have agreed to present through EHRA Essentials4U and those who have not replied yet:

• AF-FICIENT I Trial –Confirmed as of 30 March

• A prospective 12-year Registry of silicone-polyurethane copolymer-coated ICD leads

• Adjusted D-Dimer to rule out left atrial thrombus in patients with atrial fibrillation.

• Axillary vein puncture guided by ultrasound versus cephalic vein dissection in pacemaker

and defibrillator implant: a multicenter randomized clinical trial.

• DAPA Trial

• Echocardiographic outcomes in the multicenter automatic defibrillator implantation trial

chemotherapy-induced cardiomyopathy.

• The SAVE-ICD study –Confirmed as of 30 March

• Gain in CRT Efficacy with Dynamic Electrical Optimization: Real World Effect of SyncAV on

Heart Failure Hospitalizations.

• The PAINLESS Study –Confirmed as of 30 March

• Impact pilot study: improving oesophageal protection during catheter ablation for af. a

double-blind randomized controlled trial. –Confirmed as of 30 March

• Mortality and cardiac resynchronization therapy with or without defibrillation in primary

prevention

• Pacemaker implantation after balloon- or self-expandable transcatheter aortic valve

replacement in patients with aortic stenosis.

• Population-based screening or targeted screening based on initial clinical risk assessment

for atrial fibrillation: A report from the Huawei Heart Study.

• PVAC GOLD vs irrigated RF single tip catheter with contact force ablation for treatment of

symptomatic paroxysmal and persistent AF.

• The REVERSE trial –Confirmed as of 30 March

• STOP PERSISTENT AF Study –Confirmed as of 30 March

• The ESC-EHRA EORP AF General Long-Term Registry

• Standard care versus TRIVEntricular pacing in Heart Failure: A prospective multicentre

randomised control trial of triventricular pacing versus conventional biventricular pacing for

CRT.

b. EHRA experts Consensus Documents

3 documents will be made available on each of the topics: Arrhythmias, VT and CRT Titles will be available soon.

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c. Publications (E-Abstracts)

• Zero-fluoroscopy cryoablation for treatment of atrioventricular nodal reentry tachycardia in adult and pediatric patients

• Aetiology and efficacy of atrial fibrillation ablation in young adults

• Complication rate and incidence of esophageal injury after minimally invasive convergent procedure for treatment of atrial fibrillation

• Conventional fluoroscopy guided vs zero-fluoroscopy catheter ablation of supraventricular tachycardias

• 40323: Procedural differences during de novo paroxysmal atrial fibrillation ablation with a contact force-sensing ablation catheter between Europe and U.S.

• 40319: Comparison of automark utilization and lesion metric target during paroxysmal atrial fibrillation ablation with a contact force-sensing ablation catheter: European and U.S. multicenter Experiences

• Non-sustained ventricular tachycardia in nonischemic dilated cardiomyopathy: results from a nonischemic cardiomyopathy study

• Improved outcome in ablation of ventricular tachycardia in patients with structural heart disease under general anaesthetic

• Safety and efficacy of direct oral anticoagulants compared to vitamin K antagonists in patients with atrial fibrillation undergoing percutaneous coronary interventions: A meta-analysis

• Cryo-balloon ablation in elderly; Outcome and prediction of recurrence

• The increment in heart rate in cardiac resynchronization therapy: evaluation of hemodynamic and functional parameters

• Bipolar radiofrequency ablation supported by non-ionic catheter irrigation.

• Occurrence, management and outcomes of iatrogenic aortic dissections as a complication of catheter ablation. A multicenter study.

• Bipolar ablation of refractory ventricular arrhythmias originating from the close proximity of His bundle.

• Could regional electrogram desynchronization identified using mean phase coherence be potential ablation targets in persistent atrial fibrillation?

• Atrial remodeling in rat hearts after exposure to high-intensity infrasound

• Transvenous lead extraction: efficacy and safety of the procedure in octogenarian patients

• 40872: Catheter ablation for atrial fibrillation with heart failure with preserved ejection fraction

• 40921: Effect of coronary artery disease on patients with atrial fibrillation and heart failure with preserved ejection fraction - from vicious twins to vicious triplets?

• 40139: Optimizing the EP lab workflow in atrial fibrillation ablation - The use of Z stitch for groin access closure

• 40138: Improved real time recordings using the third generation cryoballoon technology - detection of dual fascicle electrograms

• Clinical outcomes of pacing induced cardiomyopathy in patients with preserved left ventricular systolic function and atrioventricular block

• Dynamic high density functional substrate mapping improves outcomes in ventricular tachycardia ablation

• Predictors of pacing induced left ventricular dysfunction and cardiomyopathy assessed by three-dimensional echocardiography and speckle tracking strain

• Added value changes in signal sonr in patients with =<30% left ventricular ejection fraction

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• Therapeutic inefficacy and pro-arrhythmic nature of metoprolol succinate and carvedilol therapy in patients with idiopathic, frequent, monomorphic premature ventricular contractions

• Cost-effectiveness of sedation for electrical cardioversion in the emergency department: a subanalysis of the Instead trial

• Low incidence of atrial tachycardia following ablation of low voltage areas in sinus rhythm for persistent atrial fibrillation

• Correction of septal flash excursion with his bundle pacing

• 41122: Prognostic impact of atrial fibrillation in STEMI patients treated by primary percutaneous coronary intervention: a focus on cardiogenic shock

• 41089: Persistent AF patients with limited areas of low voltage have a similar benefit from pulmonary vein isolation as compared to paroxysmal AF patients: insight from the SMOP study.

• Endocardial pacing is less arrhythmogenic than conventional epicardial pacing when pacing in proximity to scar in patients with ischemic heart failure.

• Ivabradine versus amiodarone for treatment of postoperative junctional ectopic tachycardia following cardiac surgery - a randomized controlled, non-inferiority trial

• Improving the optimization of cardiac resynchronization therapy: Does multipoint left ventricular pacing shorten the paced-QRS duration compared to the fusion-optimized intervals method?

• Non-invasive mapping: what is the minimal number of electrodes needed to obtain a good spatial resolution of the activation map?

• Incidence of LA fibrosis and substrate-based AF ablation success rates in HF patients

• Health-related quality of life among implantable cardioverter defibrillator patients compared to age- and sex-matched norms

• Impact of system impedance in ablation-index guided lesion formation in an in vitro model

• Cryo-ablation vs radiofrequency ablation: is there a difference between the two technologies - A single centre analysis of the sites pulmonary vein reconnection.

• Patchy localisation of late gadolinium enhancement associated with ventricular arrhythmia in dilated cardiomyopathy

• Heart rate acceleration is a poor surrogate of complete parasympathetic denervation of sinus node during cardioneuroablation

• Delayed QT interval response to heart rate acceleration due to cardioneuroablation for symptomatic bradyarrhythmias

• Estimated glomerular filtration rate levels and risk of stroke in individuals with diabetes mellitus and atrial fibrillation

• Premature Cardiac Conduction Disease in families, potential role for Implantable Loop Recorder in screening? A Case Series

• Antiarrhythmic drug therapy in Russian patients undergoing atrial fibrillation ablation: a sub-analysis of the ESC-EHRA EORP registry

• Automatic classification of 20 different types of atrial tachycardia using 12-lead ECG signals

• Incidence of ventricular arrhythmias in cardiac resynchronization therapy and implantable cardioverter-defibrillator patients

• When should we measure biomarkers in patients with atrial fibrillation to predict recurrences?

• Local impedance-guided ablation and ultra-high density mapping provide improved ablation metrics vs conventional or contact force-guided ablation for cavotricuspid isthmus dependent atrial flutter

• Pharmacological inhibition of the acetylcholine-regulated potassium channel (IK,ACh) prevents atrial arrhythmogenic changes in a rat model for obstructive sleep apnea

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• Aortic valve implantation-induced bundle branch block as a framework towards a more uniform electrocardiographic definition of left bundle branch block

• Left atrial and left atrial appendage ejection fraction assessed by preprocedural cardiac CT are useful parameters for predicting the outcome of pulmonary vein isolation

• Identification of arrhythmic isthmus in patients with transposition of the great arteries treated with atrial switch surgery using a new high-definition wavefront-activation-orientation grid catheter

• Cardiac resynchronization through His bundle pacing in patients with heart failure.

• Cardiac resynchronization through His bundle pacing in patients with heart failure.

• Atrial fibrillation and depressive symptoms in the elderly: an association with age, CHA2DS2-VASc score and physical performance

• Safety of individualised follow-up of cardiac pacemakers and implantable cardioverter defibrillators in patients undergoing radiotherapy

• The role of hyponatremia in the development of atrial fibrillation after cardiac surgery

• Epicardial abnormal electrical activity in unselected patients with ischemic ventricular tachycardia: a pilot mapping study

• Mexiletine as pharmacological treatment of recurrent and refractory ventricular tachyarrhythmias

• How does pace and ablate for poorly controlled atrial fibrillation affect heart failure metrics?

• dST-Tiso index, a new shallow ECG marker in response to ajmaline for predicting ventricular fibrillation induction in Brugada patients

• Cardioneuroablation for bradyarrhythmias and vasovagal syncope: effects corrected QT interval

• Appropriate shocks in WCD patients - Results from the Austrian WCD registry

• Non-valvular atrial fibrillation recurrence after sinus rhythm restoring at 1-year follow-up: predictors and risk stratification considering rs10465885 polymorphism in connexin-40 gene

• Combining deep learning method with optical coherence tomography for ablation lesion assessment

• Permanent his bundle pacing: conclusions from the one-year experience of a romanian center

• 41016: CRT-D versus CRT-P: are we on the right track?

• 40267 : Does papillary muscle ablation affect mitral valve function: a single centre experience.

• 40265: Effect of catheter ablation on left and right ventricular function in patients with frequent premature ventricular contractions and preserved ejection fraction.

• Association between left atrial fibrosis detected by cardiac magnetic resonance and endocardial electroanatomic mapping in the evaluation of the electrophysiological substrate in atrial fibrillation.

• CIED infection risk score validation using US health claims data

• Understanding arrhythmia mechanisms in patients with atrial septal defects

• Triage-HF Plus: identification of heart failure and non-heart failure events in an ambulatory population using remote monitoring and the triage heart failure risk score Algorithm

• The effect of post TAVR pacemaker implantation on mid and long-term mortality

• How to retrieve embolized left atrial appendage closure devices? A single center experience

• Incidence and location of PVI gaps identified post-cryoballoon ablation for atrial fibrillation

• Incidence and location of residual gaps identified by a high-density grid-style mapping catheter after PVI is confirmed by pacing the ablation lines

• Comparison of gap identification using three technologies for confirmation of pulmonary vein isolation

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• Noise-related malfunctions in modern ICDs during oncologic radiotherapy: a multicentre, real-time, in-vitro observation

• Can we predict the occurrence of persistent atrial fibrillation in large animal models to improve study efficiency?

• Silent cerebral ischemic lesions after left-sided ablation for paroxysmal supraventricular tachycardia

• Dystrophin deficient cardiomyopathy: predictors associated with the cardiac phenotype in a Duchenne registry population - A guide for device therapy.

• Novel formin homology 2 domain containing 3 (FHOD3) mutations associated with the pathogenesis of hypertrophic cardiomyopathy (HCM) in an Irish population.

• The SADS heart of the matter: a review of the sudden arrhythmic death syndrome (SADS) biobank - the cornerstone of a national strategy.

• Atrial fibrillation screen, management and guideline recommended therapy (AF SMART II) in the rural primary care setting: eHealth tools to support all stages of screening

• Heart failure and atrial fibrillation: clinical, prognostic and echocardiographic outcome

• Extended long-term follow-up of radiofrequency catheter ablation for redo procedures after pulmonary vein isolation with the cryoballoon technique (first versus second generation cryoballoon)

• Multipoint pacing in cardiac resynchronization therapy - how to improve remodeling criteria and its impact in quality of life

• A modified snare technique improves left ventricular lead implant success and response rate to cardiac resynchronization therapy

• Does high density mapping increase the efficacy of ischemic ventricular tachycardia ablation?

• Isolation of pulmonary veins with duty-cycled circular multi-polar catheter: randomized controlled clinical trial

• Circumferential pulmonary vein ablation in combination with a linear lesion at the left atrial roof for catheter ablation of persistent atrial fibrillation (8.5-year follow-up)

• Micra pacemaker implant at septal site induces a smaller increase on qrs duration than traditional pacemaker: a single center experience

• Catheter ablation of atrial fibrillation: three-dimensional transesophageal echocardiography versus magnetic resonance imaging for pulmonary vein imaging (periprocedural results and long-term follow-u

• Effectiveness of atrial fibrillation ablation using a contact force stability module with contact force or non-contact force catheter

• 12 lead Holter monitoring in Brugada syndrome

• Ultrasound-guided serratus anterior plane block for S-ICD implantation using the intermuscular technique

• 40201: Predictors of outcomes of para-Hisian ventricular arrhythmia ablation guided by electroanatomic mapping systems

• 40202: Impact of the type of electroanatomic mapping system on the incidence of cerebral embolisms after radiofrequency ablation of left atrial tachycardias

• Predictors and clinical impact of bleeding events after left atrial appendage closure in patients with high risk or a history of bleeding

• The impact of hypothyroidism on hospitalization frequency and cost-effectiveness among patients with atrial fibrillation

• Short and long-term outcomes of medical management of patients with a first episode of arrhythmic storm

• Long-term outcomes of ventricular tachycardia substrate ablation incorporating hidden slow conduction analysis

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• The automatically assessed P-wave axis predicts cardiovascular events in patients with cardiovascular risks: The Japan Morning Surge Home Blood Pressure (J-HOP) Study

• Validation of cardiologist-created, audiovisual education delivered via smart devices while awaiting outpatient consultation: optimising atrial fibrillation management through shared decision making

• External validation of a field termination-of-resuscitation rule for refractory out-of-hospital cardiac arrests in Japan

• Time boundaries of three-phase time-sensitive model for ventricular fibrillation cardiac arrest

• Estimation of no-flow duration and survival in patients with an initial shockable rhythm after out-of-hospital cardiac arrest

• Survival in children with out-of-hospital cardiac arrest after standard or chest compression-only bystander cardiopulmonary resuscitation before emergency medical services arrival

• Safety and efficacy of rivaroxaban in combination with anti-arrhythmic drugs in patients with non-permanent atrial fibrillation

• Cardiovascular, Bleeding Risks in Elderly Patients Treated With non-vitamin K antagonist or Warfarin for Nonvalvular Atrial Fibrillation: CODE-AF

• Predictors of ventricular tachyarrhythmia in patients with implantable cardioverter-defibrillator and non-ischaemic systolic heart failure

• Echocardiographic predictor of sick sinus syndrome following catheter ablation of persistent atrial fibrillation

• Association between left atrial appendage dysfunction and thromboembolic risk in nonvalvular atrial fibrillation

• SERCA2 Cys674 modification lead to ventricular arrhythmia due to impaired sarcoplasmic reticulum Ca2+ handling

• Routine use of transoesophageal echocardiography in patients with atrial fibrillation or atrial flutter undergoing cardioversion

• Cryptogenic stoke and asymptomatic atrial fibrillation in a real world population: a single centre, implantable loop recorder study

• Cardiac pacemakers and transient electromagnetic interferences during radiotherapy courses: a multicentre, real-time, in-vitro evaluation

• Permanent cardiac implantable device damage during direct photon exposure for oncologic radiotherapy: a multicentre, in-vitro observation

• Short and long term efficiency of different therapeutic approaches to perimitral atrial flutter

• Ultrasound guidance for femoral venous access in patients undergoing pulmonary vein isolation: a quasi-randomized study

• Radiofrequency ablation of left atrium in patients with mitral valve replacement. The future of surgical treatment for atrial fibrillation in mitral valve disease?

• Cerebral thromboembolic risk in atrial fibrillation ablation: a direct comparison of vitamin K antagonists versus non-vitamin K-dependent oral anticoagulants

• Conversion test during Subcutaneous Implantable Cardioverter-Defibrillator Implantation in clinical practice: in-hospital and mid-term outcome

• Causes, safety and outcomes of switching from the Initial direct oral anticoagulant to another in patients with non-valvular atrial fibrillation from a single-center prospective study

• Safety and efficacy of atrial fibrillation cryoballoon ablation according to patients' age: results from a multicenter Italian Project

• Radiation safety and electrophysiologists: radiation protection status

• Aldosterone plasma level as risk factor of ventricular arrhythmias in heart failure with preserved ejection fraction

• Plasma aldosterone level in different forms of atrial fibrillation

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• 40625: Smartphone monitor kardia: an effective diagnostic tool for paroxysmal palpitations

• 40431: Patients with cardiac implantable electronic device undergoing radiotherapy, a national audit across french cardio-electrophysiology departments

• 40340: Patients with cardiac implantable electronic device undergoing to radiotherapy, a national audit across french radiotherapy departements

• The results of whole exome sequencing in patients with bradyarrhythmias

• Impact on safety, efficacy and quality of life of atrial fibrillation catheter ablation in athletes: a propensity score analysis

• Cardiological involvement in lamin a/c disease: a multicentre experience

• The difference in the prognosis among three categories of the post-procedural left ventricular ejection fraction in patients undergoing atrial fibrillation ablation

• Accuracy of three algorithms in predicting accessory pathway localization in a pediatric population with ventricular pre-excitation

• Reduction of radiation exposure using an optimized fluoroscopy protocol in cryoballoon ablation does not compromise clinical outcome

• Cryoablation versus Radiofrequency Ablation of the Atrioventricular Node in Patients with His-bundle Pacing

• Ventricular dysfunction and fibrosis precedes atrial conduction defects in JDP2 overexpressing mice

• Ultrasound-guided axillary vein puncture feasibility for complex cardiac devices implantation.

• Effectiveness of atrial flutter ablation line selection using SOUNDSTAR catheter

• Heart rhythm disorders in Acromegaly

• Outcome of leadless pacemaker implantation in a referral centre for lead extraction: a comparison with transvenous pacemaker

• Does the reduced left ventricle ejection fraction affect the results of transvenous lead extraction?

• Asymptomatic masses on the pacing leads - influence on long term survival

• Lead dependent tricuspid dysfunction- mechanism and treatment

• Does the reduced left ventricle ejection fraction affect the results of transvenous lead extraction?

• Assessment of intraatrial conduction during staged catheter ablation of persistent AF

• Assessment of intraatrial conduction during staged catheter ablation of persistent AF

• Safety of individualised follow-up of cardiac pacemakers and implantable cardioverter defibrillators in patients undergoing radiotherapy

• Cardiac response to live music performance: effect of large-scale musical structure on action potential duration

• The natural history of atrial fibrillation after the first clinical episode: a prospective observational study via implantable loop recorders

• The natural history of atrial fibrillation after the first clinical episode: a prospective observational study via implantable loop recorders

• Late gadolinium enhancement with cardiac magnetic resonance imaging demonstrates left ventricular involvement is under-recognized in arrhythmogenic right ventricular cardiomyopathy

• General anesthesia improved rate of first-pass pulmonary vein isolation by radiofrequency ablation in patients with atrial fibrillation

• Ambulatory implantation of cardiac rhythm management devices: a retrospective safety and cost-minimization analysis in a developing country

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• Improvement of left ventricular ejection fraction in the first week post rhythm restoration as a marker of long-term recovery of arrhythmia-induced cardiomyopathy in a latin american population

• Serratus anterior plane block in subcutaneous implantable cardioverter defibrillator implantation: a case-control analysis

• Complications in young ICD patients - a retrospective analysis.

• Brugada Syndrome: is the addition of the electrocardiographic risk markers the clue?

• Defibrillation threshold with subcutaneous implantable-cardioverter defibrillator implanted using an intermuscular 2-incision approach

• Are 40 joules enough for successfully defibrillate with subcutaneous implantable cardioverter-defirbrillator?

• Obesity and metabolic syndrome is associated with QTc prolongation and arrhythmic risk: results from 24,924 participants in the UK Biobank

• First results of molecular autopsy examinations in sudden cardiac death drawn from nationwide multidisciplinary and multicentric collaboration in the Czech Republic

• Influence of body mass index on recurrence in atrial fibrillation patients after radiofrequency catheter ablation

• First evidence of trapped reentry as dormant source of acute atrial fibrillation and fractionated atrial electrograms under sinus rhythm

• Persistent atrial fibrillation terminates during ablation more often using dispersion mapping than with fractionated electrogram mapping

• Left atrial function by echocardiography is independent of degree of left atrial electrical scar

• Optimal fusion vs. biventricular pacing in cardiac resynchronization therapy: long-term results of 540 consecutive patients

• Cardiac resynchronization therapy in left ventricular non-compaction: long-term results in a series of 40 patients

• Complete non-inducibility after radiofrequency ablation for electrical storm improves survival rates

• Electrocardiographic characteristics of metastatic cardiac tumors presenting with ST-segment Elevation

• Syncope in the emergency department: can 24-hour holter monitoring be of any help?

• Prevalence and location of residual leaks following percutaneous left atrial appendage occlusion: the importance of 3D transesophageal echocardiography

• Digoxin in patients with advanced heart failure and sinus rhythm - Is there any benefit?

• Additional benefits of non-conventional modalities of cardiac resynchronization therapy using His bundle pacing

• High power radiofrequency ablation with fixed short duration for pulmonary vein isolation is associated with lower early recurrence of pulmonary vein conduction and less esophageal temperature rise

• Efficacy and safety of a modified Natale approach in ablation treatment of persistent atrial fibrillation

• Change in QRS area after CRT is associated with mortality, independent from baseline QRSarea

• Efficacy of multi-electrode linear irreversible electroporation

• The efficacy of electrical cardioversion of long-standing persistent or permanent atrial fibrillation in cardiac resynchronization therapy recipients.

• 40496: Flecainide or propafenone oral bolus to facilitate electrical cardioversion of persistent atrial fibrillation

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• 40881: Role of an extensive diagnostic work-up in the detection of concealed cardiomyopathies in athletes with complex ventricular arrhythmias and implications for sports' eligibility assessment

• Prediction of left ventricular dysfunction: comparison of clinical characteristics, ECG parameters, and NT-proBNP in a community-based cohort presenting to hospital.

• A machine learning classification algorithm to detect patients with paroxysmal atrial fibrillation during sinus rhythm

• An automated beat exclusion algorithm to improve beat-to-beat P-wave morphology analysis

• A machine learning classification algorithm to detect patients with paroxysmal atrial fibrillation during sinus rhythm

• An automated beat exclusion algorithm to improve beat-to-beat P-wave morphology analysis

• Understanding the multiple P-wave morphologies in paroxysmal atrial fibrillation, during sinus rhythm, using computer simulation

• Impact of automatic screening and parasternal rights positions in the eligibility of patients with hypertrophic cardiomyopathy for subcutaneous automatic cardioverter defibrillator implant

• Composite electroanatomical maps locate rapid activity within low voltage zones in persistent AF

• Pattern of rapid activity is preserved in persistent AF in selected locations after pulmonary vein isolation

• Does AF always beget AF? Retrospective study in patients with complex cardiac devices.

• Anticoagulation profile if an as required oral anticoagulation strategy is used in patients with complex cardiac devices

• Effect of age, genetic background and experimental conditions on left atrial monophasic action potential duration, effective refractory period and activation time in Langendorff-perfused murine hearts

• Atrial fibrillation during acute myocardial infarction : a prospective multicenter study

• Role of wearable device recordings in clinical decision making - The wEHRAbles Young EP survey

• Electrocardiographic and clinical predictors for permanent pacemaker requirement after transcatheter aortic valve implantation: a 10-year single center experience.

• Catheter ablation in adults with Wolff-Parkinson-White syndrome: a 'real-life' experience

• Impact of radiation/chemotherapy for breast cancer on the electroanatomic features in patients receiving catheter ablation for left atrial arrhythmia.

• Wireless ECG embedded in a necklace enables reliable detection of atrial fibrillation

• Conventional ablation with half normal saline is equivalent to high power short duration ablation with normal saline

• Comparison of the long-term performance of the quadripolar IS-4 and the bipolar IS-1 left ventricular lead for cardiac resynchronization therapy

• Hypertrophic cardiomyopathy and other forms of left ventricular hypertrophy. The P wave can make the difference

• Arrhythmic burden in patients with filamin C (FLNC) truncating variant associated cardiomyopathy

• Anatomical approach for permanent His-bundle pacing using coronary sinus ostium as a reference

• Could baseline electrical parameters be a marker of arrhythmia occurrence and poorer prognosis in implantable cardioverter defibrillator patients?

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• Cardiac resynchronization therapy in patients with permanent atrial fibrillation: insights from the HMEA database

• Incidence of atrial fibrillation early after cavotricuspid isthmus ablation

• CRT-D versus CRT-P: are we on the right track?

• Does papillary muscle ablation affect mitral valve function: a single centre experience.

• Effect of catheter ablation on left and right ventricular function in patients with frequent premature ventricular contractions and preserved ejection fraction.

• Novel missense variant in DPP6 in familial ventricular fibrillation