eicosanoids - vinci-biochem · 2017 1180 east ellsworth road · ann arbor, mi 48108 · usa · [800]...

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1180 EAST ELLSWORTH ROAD · ANN ARBOR, MI 48108 · USA · [800] 364-9897 WWW.CAYMANCHEM.COM 2017 Eicosanoids The eicosanoid family of signaling molecules play important roles in homeostatic regulation, metabolism, immunology and inflammation, cancer, and cardiovascular disease. Cayman Chemical is the world leader in producing synthetically pure eicosanoids, developing methods for their measurement, and generating relevant recombinant proteins and antibodies for their research. We offer more than a thousand different products for eicosanoid research that are manufactured and tested in-house to meet the highest standards of quality. Leukotrienes Thromboxanes Prostaglandins Small Molecule ELISAs Small Molecule ELISAs Biochemicals D-, E-, F-, & I-Series ELISAs Biochemicals Biochemicals Item No. Product Name 500390 Cysteinyl Leukotriene ELISA Kit 520111 Leukotriene B 4 ELISA Kit* 501070 Leukotriene C 4 ELISA Kit 501060 Leukotriene E 4 ELISA Kit Item No. Product Name 10010153 Aspirin™ Effect-Detection Kit (510(k) cleared) 501020 Thromboxane B 2 ELISA Kit* 519510 11-dehydro Thromboxane B 2 ELISA Kit - Monoclonal Item No. Product Name 319030 Thromboxane B 2 -d 4 10009584 2,3-dinor Thromboxane B 2 -d 9 19510 11-dehydro-2,3-dinor Thromboxane B 2 Item No. Product Name 512031 Prostaglandin D 2 ELISA Kit* 514531 Prostaglandin E Metabolite ELISA Kit 514010 Prostaglandin E 2 ELISA Kit – Monoclonal* 515211 6-keto Prostaglandin F ELISA Kit 516011 Prostaglandin F ELISA Kit 516521 11β-Prostaglandin F ELISA Kit 516671 13,14-dihydro-15-keto Prostaglandin F ELISA Kit 501001 tetranor-PGDM ELISA Kit Item No. Product Name 20110 Leukotriene B 4 20210 Leukotriene C 4 20310 Leukotriene D 4 20410 Leukotriene E 4 Item No. Product Name 16310 8,12-iso-iPF -VI 14840 tetranor-PGEM 16840 tetranor-PGFM 14720 15-keto Prostaglandin E 2 15120 2,3-dinor-6-keto Prostaglandin F (sodium salt) 16530 2,3-dinor-11β-Prostaglandin F 16350 8-iso Prostaglandin F 18570 15-deoxy-Δ 12,14 -Prostaglandin J 2 More than 75 analycal standards, inhibitors, and more More than 500 analycal standards, inhibitors, probes, and more More than 35 analycal standards, inhibitors, and more *Thromboxane B 2 Express ELISA Kit - Monoclonal (Item No. 10004023) also available *Leukotriene B 4 Express ELISA Kit (Item No. 10009292) also available *Prostaglandin D 2 and E 2 Express ELISA Kits (Item Nos. 512041, 500141) also available

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Page 1: Eicosanoids - Vinci-Biochem · 2017 1180 EAST ELLSWORTH ROAD · ANN ARBOR, MI 48108 · USA · [800] 364-9897 Eicosanoids The eicosanoid family of signaling molecules play important

1180 EAST ELLSWORTH ROAD · ANN ARBOR, MI 48108 · USA · [800] 364-9897 WWW.CAYMANCHEM.COM2017

EicosanoidsThe eicosanoid family of signaling molecules play important roles in homeostatic regulation, metabolism, immunology and inflammation, cancer, and cardiovascular disease. Cayman Chemical is the world leader in producing synthetically pure eicosanoids, developing methods for their measurement, and generating relevant recombinant proteins and antibodies for their research. We offer more than a thousand different products for eicosanoid research that are manufactured and tested in-house to meet the highest standards of quality.

Leukotrienes

Thromboxanes

Prostaglandins

Small Molecule ELISAs

Small Molecule ELISAs Biochemicals

D-, E-, F-, & I-Series ELISAs

Biochemicals

Biochemicals

Item No. Product Name

500390 Cysteinyl Leukotriene ELISA Kit

520111 Leukotriene B4 ELISA Kit*

501070 Leukotriene C4 ELISA Kit

501060 Leukotriene E4 ELISA Kit

Item No. Product Name

10010153 Aspirin™ Effect-Detection Kit (510(k) cleared)

501020 Thromboxane B2 ELISA Kit*

519510 11-dehydro Thromboxane B2 ELISA Kit - Monoclonal

Item No. Product Name

319030 Thromboxane B2-d4

10009584 2,3-dinor Thromboxane B2-d9

19510 11-dehydro-2,3-dinor Thromboxane B2

Item No. Product Name

512031 Prostaglandin D2 ELISA Kit*

514531 Prostaglandin E Metabolite ELISA Kit

514010 Prostaglandin E2 ELISA Kit – Monoclonal*

515211 6-keto Prostaglandin F1α ELISA Kit

516011 Prostaglandin F2α ELISA Kit

516521 11β-Prostaglandin F2α ELISA Kit

516671 13,14-dihydro-15-keto Prostaglandin F2α ELISA Kit

501001 tetranor-PGDM ELISA Kit

Item No. Product Name

20110 Leukotriene B4

20210 Leukotriene C4

20310 Leukotriene D4

20410 Leukotriene E4

Item No. Product Name

16310 8,12-iso-iPF2α-VI

14840 tetranor-PGEM

16840 tetranor-PGFM

14720 15-keto Prostaglandin E2

15120 2,3-dinor-6-keto Prostaglandin F1α (sodium salt)

16530 2,3-dinor-11β-Prostaglandin F2α

16350 8-iso Prostaglandin F2α

18570 15-deoxy-Δ12,14-Prostaglandin J2

More than 75 analytical standards, inhibitors, and more

More than 500 analytical standards, inhibitors, probes, and more

More than 35 analytical standards, inhibitors, and more*Thromboxane B2 Express ELISA Kit - Monoclonal (Item No. 10004023) also available

*Leukotriene B4 Express ELISA Kit (Item No. 10009292) also available

*Prostaglandin D2 and E2 Express ELISA Kits (Item Nos. 512041, 500141) also available

Page 2: Eicosanoids - Vinci-Biochem · 2017 1180 EAST ELLSWORTH ROAD · ANN ARBOR, MI 48108 · USA · [800] 364-9897 Eicosanoids The eicosanoid family of signaling molecules play important

1180 EAST ELLSWORTH ROAD · ANN ARBOR, MI 48108 · USA · [800] 364-9897 WWW.CAYMANCHEM.COM2017

Eicosanoid Metabolism

View a complete list of our eicosanoids at www.caymanchem.com

Cyclooxygenases

Lipoxygenases

COX Inhibitor Screening Assay KitsScreen for COX-1 or COX-2 inhibitors

Lipoxygenase Inhibitor Screening Assay Kit Item No. 760700

Enzymes

Enzymes

Antibodies

Antibodies

Item No. Product Name

17616 COX-1 (human recombinant)

60100 COX-1 (ovine)

60122 COX-2 (human recombinant)

18356 COX-2 (ovine recombinant)

Item No. Product Name

60402 5-Lipoxygenase (human recombinant)

10341 12-Lipoxygenase (platelet-type, mouse recombinant)

10011263 15-Lipoxygenase-2 (human recombinant)

Item No. Product Name

160110 COX-1 Monoclonal Antibody (Clone CX111)

160112 COX-2 Monoclonal Antibody (Clone CX229)

160106 COX-2 (mouse) Polyclonal Antibody (aa 570-598)

100034 Goat Anti-COX-2 (human) Affinity-Purified Polyclonal Antibody

Item No. Product Name

160402 5-Lipoxygenase Polyclonal Antibody

10007820 5-Lipoxygenase (Phospho-Ser523) Polyclonal Antibody

160704 15-Lipoxygenase-1 (rabbit) Polyclonal Antiserum

10004454 15-Lipoxygenase-2 Polyclonal Antibody

• Measure peroxidase activity or prostaglandin F2α

• Includes purified human and/or ovine enzymes• Plate-based colorimetric or fluorometric formats • 10 kit variations available• More than 80 COX inhibitors available

• Screen for inhibitors of purified 5-, 12-, or 15-LO• Includes 15-LO• Measure the hydroperoxides generated from LOs• Plate-based colorimetric measurement (490-500 nm)• More than 35 LO inhibitors available

An accurate and convenient method for screening lipoxygenase inhibitors. This assay measures the hydroperoxides generated from the incubation of a lipoxygenase (5-, 12-, or 15-LO) with either arachidonic or linoleic acid.

Determine the best kit for your research with ourKit Recommendation Guide available online at www.caymanchem.com/kitrecommendations

In Italy: Vinci-Biochem SrlContatto diretto: tel. 0571 568 [email protected]

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