emg
TRANSCRIPT
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EMG
Theory of NCS/EMG
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EMG
• Is an extension of the neurological examination.• The EMG examination is a diagnostic tool used in
the evaluation of pain, weakness, sensory disturbance, fatigue and atrophy
• The EMG examination includes two components: Nerve Conduction Studies (NCS) and the needle electromyographic (EMG) study.
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Localize the Problem
• Nerve
• Root
• NMJ
• Muscle
• Axonal• Segmental• Focal
• Pre-synaptic• Post-synaptic
• Neuropathy• Myopathy• Upper Motor Neuron
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NCS
• In NCS or electrical studies, response amplitudes and latencies are evaluated.
• Nerve Conduction Velocity (NCV) studies may be used to evaluate axonal, segmental and focal peripheral nerve problems.
• Other NCS techniques may be used to evaluate problems in the neuromuscular junction (NMJ), nerve root and even central nervous system.
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Nerve Studies
• Focal and Segmental neuropathy (CTS, GB, CMT, Heavy metal poising):NCV: MNC, SNC
• Axonal (ALS, Neuropathies secondary to alcoholism):NCV: MNC, SNC, F-waves, MUNE, CVD
• Other (MG):MNC, SNC, F-wave, Rep. Stim., H-wave, Blink, MUNE
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MNC
• Supramaximal stimulation at the Wrist produces a Compound Muscle Action Potential (CMAP) from the thenar muscles.
• The distal latency (W) includes the terminal axon transmission time + the delay time at the NMJ including the time required for generation of the CMAP after depolarization of the motor end plate.
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MNCV• Supramaximal stimulation at the Elbow
produces a Compound Muscle Action Potential (CMAP) from the thenar muscles.
• The nerve conduction time from the elbow to the wrist equals the latency difference between the distal latency (W) and the proximal latency (E).
• The Motor Nerve Conduction Velocity (MNCV) is calculated by dividing the distance between the two cathode stimulation points by conduction time.
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Three Basic Responses
• Normal or Near Normal:
Response latency is normal. Response amplitude is normal or near normal.
• Delayed:
Increased latency and normal or decreased amplitude
• Absent:
No response to supramaximal stimulation.
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Acute Conduction Block
• Three stimulation sites: ankle, fibula head and popliteal fossa
• Note the amplitude drop in the CMAP between the two proximal stimulation sites
• Conduction velocity my be normal or slightly increased
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Possible Sources of Error• Sub supramaximal stimulation.
Unreliable response amplitudes
• Excessive stimulation.
Artificially decreased latencies.
• Measurement errors.
Inaccurate measurements across joints, e.g.., ulnar nerve across the elbow.
• Martin-Gruber Anastomosis.
Communication from the median to the ulnar nerve at the forearm.
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Motor and Sensory Potentials
• Compound Muscle Action Potential (CMAP)
Amplitude: 4-16 mV
Duration: 4-6 ms
<10% amplitude loss between stimulus sites.
• Sensory Nerve Action Potentials (SNAP)
Amplitude: 10-100 V
Duration: 1.5-2.5 ms
20-30% amplitude loss between stimulus sites.
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F-waves• Supramaximal stimulation required.
• With each stimulus, <5% of motor axons in nerve produce a F-wave.
• From each stimulus a different population of motor axons produce f-waves.
• F-waves are evoked single Motor Unit Action Potentials (CMAP)
• Latency variation is due to variation in conduction velocity of individual motor axons.
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H-waves• A mono-synaptic response
analogous to the Achilles tendon tap reflex.
• Do not vary in latency.
• Must be larger than M-wave.
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Blink Reflex
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Repetitive Stimulation• Supramaximal Stimulation.
• 4 to 10 stimuli at 2-3 Hz.
• Maximal amplitude drop by 4th or 5th response.
• Amplitude and Area should both decrement.
• Typical test sequence:
pre-exercise, 30-60s exercise,
3 s post-exercise, 2 min post-exercise, 10 min post-exercise
• Movement related artifact (bottom) from changes in the muscle shape during recording.
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Needle Exam
• The needle EMG examination is used to evaluate problems in muscle, the NMJ and The Motor Unit.
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Needle Studies
• Routine needle EMG
SPA, MUP, MVA: Radicular lesions, Axonal degeneration, Muscle weakness
• Quantitative EMG
QMUP, AMUP, IPA: Axonal degeneration, muscle weakness
• SFEMGSFEMG: MG, Myasthenic Syndrome, Botulinum intoxication, Tetany, Myotonia, MD, Polymyositis.
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EMG Findings
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Spontaneous Activity
• Insertion Activity:
• Fibrillation Potentials:
• Positive Sharp Waves:
• End-Plate Activity:
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Distinctive EMG Potentials
• Myotonic Discharge: Repetitive at rates of 20 to 80 Hz. The amplitude and frequency of the potentials must wax and wane.
• Complex Repetitive Discharge (CRD): A polyphasic or serrated action potential that may begin or end abruptly. They are uniform in shape and amplitude. They may spontaneously change configuration.
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More EMG Discharges
• Myokymic Discharge: Three different myokymic discharges. To illustrate the firing pattern, the traces on the left are 7 s long and the ones on the right are 1s long.
• Cramp Discharge: Arise from involuntary repetitive firing of the motor unit action potential at a high rate (up to 150 Hz). Each trace is 5 s long.
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Normal EMG Activity
• Recruitment Pattern: Recruitment refers to successive activation of the same and new motor units with increasing strength of voluntary muscle contraction.
• Motor Unit Action Potentials (MUAPs): Action potentials reflecting the electric activity of a single motor unit.It is a compound action potential of those muscle fibers within the recording range of the electrode.
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Upper Motor Neuron Lesion
Typical Findings
• Insertional Activity:
Normal
• Spontaneous Activity:
None
• MUAPs:
Normal
• Interference Pattern:
Reduced pattern with individual MUAPs firing at a slow rate
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Lower Motor Neuron Lesion
Typical Findings
• Insertional Activity:Increased
• Spontaneous Activity:Fibrillation & Positive Waves
• MUAPs:Large, Polyphasic with reduced recruitment
• Interference Pattern:Reduced pattern with individual MUAPs firing at a fast rate
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Myogenic Lesion
Typical Findings
• Insertional Activity:Normal
• Spontaneous Activity:None
• MUAPs:Small, Polyphasic with early recruitment
• Interference Pattern:Full, low amplitude pattern at less than maximal effort