"enabling individual wellness through computational systems biology, cloud analytics,...

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M O U N TA I N V I E W, C A

Riaan Conradie PhD LifeQ President & Co-Founder

Enabling individual wellness through computational systems biology,

cloud analytics, wearables, machine learning and more

photo credit: http://www.awaken.com/2014/12/peter-h-diamandis/

http://www.awaken.com/2014/12/peter-h-diamandis/

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photo credit: www.visiblebody.com

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Credit: The Economist. Original data sources: Health Expenditure from the OECD, Life Expectancy from the World Bank. Licensed under CC-BY-SA by the author Max Roser. The data visualization is available at OurWorldinData.org and there you will find more research

and visualizations on the topic.

• In 1960 the average American only worked 15 days to cover their whole year worth of health insurance.

• The average earner in the States currently works for 2 months a year just to cover their healthcare bill

• Almost 1 in 5 Dollars of US GDP are pushed into healthcare.

• 30% of all Medicare expenditures are attributed to the 5% of beneficiaries that die each year, with 1/3 of that cost occurring in the last month of life!!

• The shocker statistic…about 90% of the total healthcare bill is due to chronic disease that is largely preventable!

• Society of Actuaries (SOA) released its latest annual mortality improvement scale for pension plans earlier this month. They found that, despite all of the amazing healthcare innovation, the average 65-year-old American male was expected to live to 86.2 in 2015, while the average female of the same age was expected to live to 88.2. New projections by the SOA posit that life expectancy for 65-year-old males is more like 85.8, and 87.8 for females of the same age.

• Price hikes: Epipen price increase from about $60 in 2007 to $600 in 2016. Turing Pharmaceuticals increased the price of a drug by 4000% in a single year.

http://OurWorldinData.org

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Our current environment is, in many ways, not fundamentally serving us well

at an individual and at a population level.

What about this dream of a world of abundance? Many even ask: Is technology maybe even bad for us?

…or… - Technology has been largely applied, in a very siloed way, to address

individual human needs. (Most likely a technology growth phase we are in!) - Technology outputs are, in many cases, not accessible to the individual or

the population at large. Information is guarded by a group of experts and cannot be judged on overarching outcomes.

The world is fortunately shifting technological gears, and technologists have new tools to their disposal: faster, cheaper, more powerful and lower power processing, more and new ways of connecting things, remote processing, remote data storage, increased data transfer rates & new ways to sense.

This is however not enough, and apart from technology innovation we will need to also focus on systems design: • put the user behind the steering wheel, where we, as scientists and

technologists, are the participants. User controlled and user ownership should be a key priority.

• promote true, non siloed, collaboration between different players (data providers, data transformers and content delivery)

• A technology world allowing for positive network effects. Think exclusivity. • Not solely rely on big data approaches, but also consider that big data needs

big theory.

“Rather than continuing to fund, pursue and promote ‘blind’ big data projects with massive budgets, we call for more funding to be allocated to the elucidation of the multiscale and stochastic processes controlling the

behaviour of complex systems, including those of life, medicine and healthcare.”

Big data need big theory too

Peter V. Coveney, Edward R. Dougherty, Roger R. Highfield Published 3 October 2016.

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User Driven Healthcare & Wellnessphoto credit: www.visiblebody.com

de-identification and user driven switch

environment (including social)

physiological

LifeQ Core

behavior & mood

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User Driven Healthcare & Wellnessphoto credit: www.visiblebody.com

de-identification and user driven switch

behavior & mood

environment (including social)

physiological

LifeQ Coreother data

transformers

content providers

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1. Wearable Device Enablement2. Content Acquisition Enablement3. LifeQ CORE Analytics and Modeling4. Data Transformation Enablement5. Information Delivery Enablement6. Content Delivery Enablement7. De-Identification and API Switching Protocol

Technology Components to Enable Data Provision, Transformation and Consumption

Information Signalng/Switching & User De-identification Service

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DE-IDENTIFIEDUSER

Personalized Physiological Information Streams

LIFEQ COREANALYTICS & MODELING

HEALTH & LIFE INSURERS, CARE PROVIDERS

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3RD PARTY DATATRANSFORMERS

disease prevention, lower insurance cost and better quality, higher access and

lower cost care when required

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Current Pilots To Address Corporate Wellness Needs

Engagement Metrics(sleep architecture, acute stress,calorie expenditure, fitness metrics,heart health metrics, etc.)

Individualized health risk and life risk metrics(cardiovascular health, relative risks for all cause and cardiovascular mortality)

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Corporate

Insurance

Reinsurance

Wearable Deviceenabled with LifeQ

embedded algorithms User Engagement Component

risk underwriting

user demographics

LifeQ enableddata streams

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LifeQ Cloud basedmodeling & analytics

LifeQ Enabled Garmin Device

20+ measures and metrics available from the LifeQ API

Breathing rate within 2 breaths per minute for 94% of the duration of a subjects sleep

LifeQ Sleep Apnea solution vs polysomnography analysis. R=0.85

Sleep related outputs:Cohen’s kappa on par with in field EEG based FDA approved devices.

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)The hue’s of age

blue(young) to orange(old)

Individual with Atrial Fibrillation

Healthy individual

n = 1 :)

A super exciting line-up (and that’s juts for today!)

Abundance, yes, but in a user-driven world where scientists & technologists act not only as abundance creators, but also

as resource usage advisors that understand the individual users.

This will be the most likely way we will reach abundant wellbeing.