endocrine system 2
DESCRIPTION
The endocrine systemTRANSCRIPT
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By Darth Benjamanus
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Signals in Animals
Hormones: Chemical signals that convey information between organs
Pheromones: chemical signals between different individuals
EX: Mating attractions
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HORMONES Only target cells receive
message They elicit a specific
response Over 50 known hormones
in the human body Steroid hormones
(including sex hormones) are lipid molecules the body makes from cholesterol
Bind to specific protein receptors inside pm
Non-steroid hormones bind to specific receptors outside plasma membrane
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Hormones Bind to Specific Receptors!
Hormones act at very low concentrations
Signal transduction pathway: sequence of steps that enable a hormone to produce an intracellular change
Steroid receptors are specialized proteins within the cells
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Chemical signals are relayed and amplified by 2nd messengers and protein kinases
Earl W. Sutherland- pioneer for endocrine system, received Nobel prize 1971.
CAMP- Cyclic Adenosine Monophosphate
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Signals Signal transduction involving cAMP: binding of a hormone to surface
receptor activates G protein (relay)
Activates anenylyl cyclase (effector) to produce cAMP,
Which activates cAMP-dependent protein kinase, enzyme that phosphorylates proteins
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Invertebrate control systems integrate both endocrine and nervous system functions.
Diverse hormones regulate different aspects of homeostasis in invertebrates.
Hormones controlling reproduction and development have been extensively researched
Different job, different hormone.
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Target Cells
Specific hormones target specific cells While one cell may be affected by a
hormone, its neighbors may remain untouched
(Target cell)
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Pheromones (again)
Carry messages in between different individuals of a species, as in mate attraction
DARK MARK, YO!
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Local Regulators Growth Factors: peptides and proteins
that stimulate cell proliferation Nitric Oxide: Highly reactive, triggers
changes in a target cell w/in a few seconds of contact and then breaks down;
Functions as a neurotransmitter, kills cancer cells relaxes muscles
Prostaglandins (PGs)- modified fatty acids Stimulate contractions in the
smooth muscles in the wall of the uterus, during both intercourse and labor
REGULATE THIS!!
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Vertebrate Endocrine System
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Hypothalamus
In brain, controls other glands
Like a boss!
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Pituitary gland Promotes kidney water
retention Stimulates:
contraction of uterus and mammary gland cells
growth(especially bones) and metabolic functions
production of sperm/ova ovaries and testes thyroid gland adrenal cortex to secrete
glucocorticoids
I’m the boss!
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Pituitary gland= the boss!
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Parathyroid Glands:
Stimulate and maintain metabolic processes Lowers blood calcium level Thyroxin- Hormone that controls metabolism
Raise blood calcium level (homeostasis)
Thyroid Gland:
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Pancreas
Insulin: Lowers blood glucose level Glucagon: Raises blood glucose level
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Adrenal Glands Raise blood glucose
level Increase metabolic
activities Constrict certain blood
vessels Promote re-absorption
of sodium and excretion of potassium in kidneys
Epinephrine or norepinephrine
Fight or Flight!!
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Testes Secrete Testosterone Support sperm formation Promote development and
maintenance of male secondary sex characteristics
Ovaries Secrete Estrogen Stimulate uterine lining
growth Promote development and
maintenance of female secondary sex characteristics
(Gonads)
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Pineal Gland
Secretes MelatoninInvolved in Biological Rhythms
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Thymus Gland
Stimulates T Lymphocytes
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NOW GET OUT THERE, AND PUNCH THAT TEST IN THE FACE!!!
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Who’s your DADDY???
This has been…..
a Darth Benjamanus Production