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  • 7/28/2019 Energy From Cell

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    Copyright 2009 Pearson Education, Inc.

    Active Lecture Questions for

    Biology: Concepts & Connections, Sixth EditionCampbell, Reece, Taylor, Simon, and Dickey

    Chapter 6 How Cells Harvest ChemicalEnergy

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    Copyright 2009 Pearson Education, Inc.

    Answer

    Some prokaryotic and all eukaryotic cells use oxygen to harvest

    energy from food molecules? In what form is that energyavailable to power cell work?

    4) ATP molecules.

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    Concept Check

    The figure above represents an overview of the different processesof cellular respiration. Which of the following correctly identifies thedifferent processes?

    1) 1. Glycolysis; 2. Electron transport chain; 3. Krebs cycle

    2) 1. Glycolysis; 2. Krebs cycle; 3. Electron transport chain

    3) 1. Krebs cycle; 2. Electron transport chain; 3. Glycolysis

    4) 1. Electron transport chain; 2. Glycolysis; 3. Krebs cycle

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    Answer

    The figure above represents an overview of the different processesof cellular respiration. Which of the following correctly identifies thedifferent processes?

    2) 1. Glycolysis; 2. Krebs cycle; 3. Electron transport chain

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    Copyright 2009 Pearson Education, Inc.

    Cytoplasm

    Glucose

    FADH2

    Mitochondrion

    Maximum per glucose:

    OXIDATIVEPHOSPHORYLATION

    (Electron Transport

    and Chemiosmosis)

    CITRIC ACIDCYCLE

    Electron shuttleacross membrane

    2 NADH

    2 NADH

    2 NADH

    6 NADH 2

    (or 2 FADH2)

    2 Acetyl

    CoA

    GLYCOLYSIS2

    Pyruvate

    About38 ATP

    about 34 ATPby substrate-levelphosphorylation

    by oxidative phosphorylation

    2 ATPby substrate-levelphosphorylation

    2 ATP

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    6.13 Fermentation enables cells to produce ATP without oxygen

    Fermentation is an anaerobic (without oxygen) energy-generating process

    It takes advantage of glycolysis, producing two ATP

    molecules and reducing NAD+ to NADH

    The trick is to oxidize the NADH without passing its

    electrons through the electron transport chain to

    oxygen

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    6.13 Fermentation enables cells to produce ATP without oxygen

    Your muscle cells and certain bacteria can oxidize NADHthrough lactic acid fermentation

    NADH is oxidized to NAD+ when pyruvate is reduced to

    lactate

    In a sense, pyruvate is serving as an electron sink, a

    place to dispose of the electrons generated by oxidation

    reactions in glycolysis

    Copyright 2009 Pearson Education, Inc.

    Animation: Fermentation Overview

    http://localhost/var/www/apps/conversion/tmp/scratch_3/06_13FermentationOverview_A.html
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    Glucose

    NADH

    NAD+

    2

    2

    NADH2

    NAD+2

    2 ADP

    P

    ATP2

    2 Pyruvate

    2 Lactate

    GLYCOLYSIS

    Lactic acid fermentation

    2

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    6.13 Fermentation enables cells to produce ATP without oxygen

    The baking and winemaking industry have used alcoholfermentation for thousands of years

    Yeasts are single-celled fungi that not only can use

    respiration for energy but can ferment under anaerobic

    conditions

    They convert pyruvate to CO2 and ethanol while

    oxidizing NADH back to NAD+

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    2 ADP

    P

    ATP2 GLYCOLY

    SIS

    NADH

    NAD+

    2

    2

    NADH2

    NAD+2

    2 Pyruvate

    2 Ethanol

    Alcohol fermentation

    Glucose

    CO22

    released

    2

    Wine- grapes, water, yeast

    Beer- water, malted barley,hops and yeast

    Grains make liquors from

    mashing and yeast

    To Yeast, EtOH is toxic and

    secreted to the extracellular

    space. If you ferment toomuch, the yeast die and this

    limits the proof of what you

    are drinking.

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    Fermentation vats for wine- have one-way valves to release the CO2 but keep out

    the oxygen. Fermentation needs to happen without Oxygen.

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    6.14 EVOLUTION CONNECTION: Glycolysis evolved early in the history of life on Earth

    Glycolysis is the universal energy-harvesting process ofliving organisms

    So, all cells can use glycolysis for the energy

    necessary for viability

    The fact that glycolysis has such a widespread

    distribution is good evidence for evolution

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    INTERCONNECTIONS BETWEENMOLECULAR BREAKDOWNAND SYNTHESIS

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    6.15 Cells use many kinds of organic molecules as fuel for cellular respiration

    Although glucose is considered to be the primary sourceof sugar for respiration and fermentation, there are

    actually three sources of molecules for generation of

    ATP

    Carbohydrates (disaccharides)

    Proteins (after conversion to amino acids)

    Fats

    Copyright 2009 Pearson Education, Inc.

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    Food, such aspeanuts

    ProteinsFatsCarbohydrates

    Glucose

    OXIDATIVEPHOSPHORYLATION(Electron Transportand Chemiosmosis)

    CITRIC

    ACIDCYCLE

    AcetylCoAGLYCOLYSIS

    Pyruvate

    Amino acidsGlycerolSugars Fatty acids

    Aminogroups

    G3P

    ATP

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    Concept Check

    1) The electron transport chain is too deeply embedded in themitochondria.

    2) The electron transport chain only receives electrons carriedby reduced electron carrier molecules such as NADH.

    3) The electron transport chain only receives electrons carriedby oxidized electron carrier molecules such as NAD+.

    4) The electron transport chain does not produce ATP.

    The figure above represents an

    overview of the different entrypathways to cellular respiration when

    different macromolecules are digested

    for energy production. Why are none

    of the digestive products entering the

    electron transport chain, directly?

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    Answer

    2) The electron transport chain only receives electrons carried

    by reduced electron carrier molecules such as NADH.

    The figure above represents an

    overview of the different entrypathways to cellular respiration when

    different macromolecules are digested

    for energy production. Why are none

    of the digestive products entering the

    electron transport chain, directly?

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    6.16 Food molecules provide raw materials for biosynthesis

    Many metabolic pathways are involved in biosynthesis ofbiological molecules

    To survive, cells must be able to biosynthesize

    molecules that are not present in its foods

    Often the cell will convert the intermediate compounds

    of glycolysis and the citric acid cycle to molecules not

    found in food

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    Cells, tissues, organisms

    Proteins Fats Carbohydrates

    Glucose

    ATP needed to drive biosynthesis

    CITRICACID

    CYCLE

    Acetyl

    CoA

    GLUCOSE SYNTHESIS

    Pyruvate

    Amino acids Glycerol SugarsFatty acids

    Amino

    groups

    G3P

    ATP

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    Cytoplasm

    GlucoseOxidative

    phosphorylation

    (Electron Transportand Chemiosmosis)

    Citricacid

    cycle

    Glycolysis

    Pyruvate

    CO2

    ATP

    CO2

    ATP

    NADH and FADH2

    Mitochondrion

    NADH

    ATP

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    ATP (a) glucose and

    organic fuels

    has three stages

    producesome

    generates

    Cellularrespiration

    uses

    H+ diffusethrough

    ATP synthase

    by process called

    chemiosmosis

    energy for

    cellular work

    uses

    (b) (d)

    (c)

    (f)

    (e)

    oxidizes

    C6H12O6

    to pullelectrons down

    to

    uses pumps H+ to create

    H+ gradient

    producesmany

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    You should now be able to

    Explain how photosynthesis and cellular respiration are

    necessary to provide energy that is required tosustain your life

    Explain why breathing is necessary to support cellularrespiration

    Describe how cellular respiration produces energy thatcan be stored in ATP

    Explain why ATP is required for human activities

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    You should now be able to

    Describe the process of energy production frommovement of electrons

    List and describe the three main stages of cellularrespiration

    Describe the major steps of glycolysis andexplain why glycolysis is considered to be ametabolic pathway

    Explain how pyruvate is altered to enter the citricacid cycle and why coenzymes are importantto the process

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    You should now be able to

    Describe the citric acid cycle as a metabolicpathway designed for generating additionalenergy from glucose

    Discuss the importance of oxidativephosphorylation in producing ATP

    Describe useful applications of poisons thatinterrupt critical steps in cellular respiration

    Review the steps in oxidation of a glucosemolecule aerobically

    Copyright 2009 Pearson Education, Inc.

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