engineered for simplicity - zeiss · storage 2 – 8°c 2 – 8°c 2 – 8°c box content 1 ×...

ZEISS OVDsEngineered for simplicity

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ZEISS OVDs Peace of mind included

Engineered for simplicity

• ZEISS OVDs are the result of more than 20 years of experience

in the development and production of unique OVDs with

the excellent quality standard associated with ZEISS.

• As ZEISS OVDs and IOL technology come from one experienced

source, the products are perfectly aligned with one another.

• ZEISS OVDs originate exclusively from patented continuous

biofermentation and are therefore not based on animal tissue.

Ophthalmic viscosurgical devices (OVDs) are extremely important in determining the success of cataract surgery. However, there are other crucial aspects that you need to focus on during surgery. ZEISS OVDs are developed to support you at each step of the cataract procedure so you will never have to give them a second thought.

We respect nature. Our

OVDs do not contain animal

tissue.

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Modern OVDs from ZEISS for all requirementsFrom standard to premium viscosurgical tools

ZEISS provides a wide range of modern, innovative viscosurgical devices that fully support the surgical workflow – giving you the choice to select the OVD that best matches each individual cataract case.

The ZEISS OVD portfolio includes:

• unique OVDs such as the first and only

viscoanesthetic: VISTHESIA®,

• premium double OVDs in one device:

TWINVISC® or in two separate syringes:

COMBIVISC®,

• high-viscosity cohesive OVDs:

Z-HYALIN®, Z-HYALIN® plus,

• low-viscosity dispersive OVDs:

Z-HYALCOAT® and Z-CELCOAT®.

ZEISS also provides OVDs in multipacks, in

addition to single packs. ZEISS MULTIPACK

saves space, costs and waste.

ZEISS OVDs available in

10 syringe multipacks

• Z-HYALIN

• Z-HYALIN plus

• Z-HYALCOAT

• Z-CELCOAT

and in 5 procedures multipacks

• COMBIVISC

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VISTHESIA

The pain relief OVD

Z-HYALIN / Z-HYALIN plus

The all-round cohesive OVDs

These high-viscosity OVDs are designed to meet all expectations for every type of cataract surgery.

• Ease of use in any case

• Flexibility of a high volume syringe (1.0 ml)

• Good endothelium protection

• Highly effective in space creation

• Optimal chamber retention

• Good capsular bag inflation

• Fast and easy removal

The first and only OVD that offers an ancillary anaesthetic and an ophthalmic viscoelastic combined; providing more comfort for your patient, especially during prolonged procedures.

VISTHESIA Topical

• The ancillary lidocaine ensures comfort for the patient at the start of surgery

• The preoperative topical application with sodium hyaluronate

- coats and hydrates the epithelial cells, to support clear vision into the eye

- minimizes the need for additional hydration during surgery

VISTHESIA Intracameral cohesive OVD

• Maintains anterior chamber space

• Provides endothelial protection1 and pupil dilation2

for routine or complex cataract cases

• Ensures even dispersion of lidocaine throughout the eye to all tissue

• Precise delivery of 1% lidocaine combined into one step saves

time and preparation of a separate intracameral anesthetic

1 Poyales-Galan et al.: Clinical Evaluation of Endothelial Cell Decrease with

VISTHESIA in Phacoemulsification Surgery. JCRS, Vol. 31, Nov. 2005

2 Pandey et al.: Evaluation of the cataractogenic effect of viscoanesthetic

solutions on the rabbit crystalline lens. JCRS, Vol. 31, Jul. 2005

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TWINVISC

Two OVDs, one device

TWINVISC is an ophthalmic viscosurgical device that combines two viscoelastic solutions in a single syringe, one dispersive and one cohesive, with complementary and synergistic properties, separated by an innovative Bypass stopper system.

• Easy injection of the dispersive and cohesive

viscoelastic solutions in sequence

• Creation and maintenance of volume in the anterior

segment during capsulorhexis and implantation

• Clear view at every stage

• Protection of the endothelium and other tissue during

the various maneuvers and use of ultrasound

• Quick and easy removal

COMBIVISC

The perfect match of two OVD concepts

The optimal combination of a dispersive and cohesive OVD in two separate syringes to match the requirements at each stage of the cataract surgery. Giving you the space you need and clear vision to operate, with fast removal.

Dispersive

• Reliable endothelium protection

• Excellent optical clarity3

• Good space partition

• Short aspiration time4

• Contains Z-HYALCOAT

Cohesive

• Highly effective in space creation

• Optimal chamber retention

• Good capsular bag inflation

• Fast and easy removal4

• Contains Z-HYALIN plus

3 Hütz et al.: Comparison of viscoelastic substances used in phacoemulsification. JCRS Vol 22, Sept. 1996

4 Steve A. Arshinoff: New classification of ophthalmic viscosurgical devices. JCRS Vol 31, Nov. 2005

New Double OVD

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VISTHESIA 1.5% VISTHESIA 1.0% TWINVISC

Topical ampules Topical ampules

Origin Bacterial fermentation Bacterial fermentation –

Substance Sodium Hyaluronate (NaHA) Sodium Hyaluronate (NaHA) –

Concentration 0.3% NaHA, 2.0% lidocaine 0.3% NaHA, 2.0% lidocaine –

Volume 2 ampules of 0.3 ml 2 ampules of 0.3 ml –

Intracameral syringe Intracameral syringe Two-chamber syringe

Behavior Cohesive Cohesive Dispersive Cohesive

Origin Bacterial fermentation Bacterial fermentation Bacterial fermentation Bacterial fermentation

SubstanceSodium Hyaluronate (NaHA)

Sodium Hyaluronate (NaHA)



Concentration 1.5% NaHA,1.0% lidocaine 1.0% NaHA,1.0% lidocaine 2.2% NaHA 1.0% NaHA

Volume 1 syringe of 0.8 ml 1 syringe of 0.8 ml 0.7 ml 0.7 ml

pH 6.8 – 7.6 6.8 – 7.6 6.8 – 7.6 6.8 – 7.6

Osmolality (mOsmol/kg) 280 – 330 280 – 330 300 – 360 300 – 350

Molecular weight (Da)* Avg. 2,900,000 Avg. 2,900,000 Avg. 1,000,000 Avg. 2,000,000

Pseudoplasticity Index 80 58 13 17

Zero-Shear Viscosity (mPa.s) Avg. 187,000 Avg. 63,000 Avg. 30,000 Avg. 14,000

CDI – – 25 71

Cannula 27 G 27 G 25 G

Storage 2 – 8°C 2 – 8°C 2 – 8°C

Box content1 × intracameral syringe, 2 × topical ampules,

1 × 27 G cannula1 × two-chamber syringe,

1 × 25 G cannula

* The molecular weights are derived from intrinsic viscosity according to the Mark Houwink equation.

ZEISS OVDs Engineered for simplicity

VISTHESIA 1.5 % and VISTHESIA 1.0 % are not for sale in the UK and Portugal.

Please ask our sales representative for information about VISTHESIA 1.5 % intra and VISTHESIA 1.0 % intra.

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COMBIVISC Z-HYALIN plus Z-HYALIN Z-HYALCOAT Z-CELCOAT

– – – – –

– – – – –

– – – – –

– – – – –

Double viscosity OVD Intracameral syringe Intracameral syringe Intracameral syringe Intracameral syringe

Cohesive Dispersive Cohesive Cohesive Dispersive Dispersive

Bacterial fermentation Bacterial fermentation Bacterial fermentation Bacterial fermentation Bacterial fermentation Botanical






HydroxyPropylMethyl-Cellulose (HPMC)

1.5% NaHA 3.0% NaHA 1.5% NaHA 1.0% NaHA 3.0% NaHA 2.0% HPMC

1.0 ml 0.85 ml 1 syringe of 1.0 ml 1 syringe of 1.0 ml 1 syringe of 0.85 ml 1 syringe of 2.1 ml

6.8 – 7.6 6.8 – 7.6 6.8 – 7.6 6.8 – 7.6 6.8 – 7.6 6.8 – 7.6

300 – 360 300 – 360 300 – 360 300 – 350 300 – 360 280 – 320

Avg. 2,900,000 Avg. 1,000,000 Avg. 2,900,000 Avg. 2,900,000 Avg. 1,000,000 Avg. 86,000

91 15 91 50 15 16

Avg. 250,000 Avg. 67,000 Avg. 250,000 Avg. 50,000 Avg. 67,000 Avg. 4,900

42 15 42 60 15 –

27 G 25 G 27 G 27 G 25 G 23 G

2 – 8°C 2 – 8°C 2 – 8°C 2 – 30°C 2 – 30°C

Single pack: 2 × syringes, 1 × 25 G cannula, 1 × 27 G cannula

Multipack: 5 × pouches containing 2 syringes,5 × 25 G cannulae, 5 × 27 G cannulae

Single pack: 1 × syringe, 1 × 27 G cannulaMultipack: 10 × syringes, 10 × 27 G cannulae



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Carl Zeiss Meditec AG Goeschwitzer Str. 51–5207745 JenaGermanywww.zeiss.com/ovdwww.zeiss.com/contacts

0297 Z-CELCOAT0344 VISTHESIATWINVISCZ-HYALINZ-HYALCOATCOMBIVISC

Carl Zeiss Meditec AGGoeschwitzer Str. 51–5207745 JenaGermanywww.zeiss.com/ovdwww.zeiss.com/contacts

Hyaltech Ltd.Starlaw Business ParkLivingston EH54 8SFUnited Kingdomwww.zeiss.com/ovdwww.zeiss.com/contacts

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