english version pain management may 2008 london management - prof... · guna®--matrix matrix drops...
TRANSCRIPT
BBüürgi Effectrgi Effectgg
Different pharmacologically active substances mixed together have a potentiatingmixed together have a potentiating
synergistic effect
1© Dipartimento Scientifico Guna S.p.a.
Chamomilla 1X*•Organotrophism and
GUNAGUNA®®--TRAUMA TRAUMA dropsdrops
Chamomilla 1X*Hypericum 3X*
Arnica 3X**Hamamelis 2X**
Bellis 2X***
•Organotrophism andcarrier function forhomologous humantissues Bellis 2X
Calendula 1X****Symphytum 3X****
Ruta 3XKalmia 8XC ti 12/30/200X Kalmia 8X
Rhus tox. 6XBryonia 6X
Connective 12/30/200XBone 12/30/200X
Cartilago 12/30/200X
•Modulation of all inflammatory process development phases (neurogen*, vasal**, PNEI COREexudative***, restitutio ad integrum****)
•Tropism remedies, specific for bones muscles tendons
•Stop to IL1, starter of inflammatory process*
•The stimulation of the for bones, muscles, tendons, ligaments, synovia
•Activity aimed at all the functional components of
Anti IL 1 4C*
TGF-beta 1**
IL 10**
cytokines having Th2-Th3 polarity modulates inflammation**
3
ortho-traumatologic painBeta-Endorphin 6X***
•Analgesic action***
© Dipartimento Scientifico Guna S.p.a.
• SYMPTOMS CONTROLACONITUM 6/12/30/200X
GUNAGUNA®®--FLAM FLAM dropsdrops
ACONITUM 6/12/30/200XAPIS 6/12/30/200XBELLADONNA 6/12/30/200XFERRUM PHOSP. 6/12/30/200X
• DRAINAGE
CONNECTIVE TISSUE 12/30/200X
d
HEPAR SULF. 6/12/30/200XPYROGENIUM 30/200XBRYONIA 6/12/30/200XPHYTOLACCA 6/12/30/200X Homeopathic and
Classic
and PHYTOLACCA 6/12/30/200X
• CELL METABOLIC SUPPORT• CELL NUTRITIONAL
SUPPORT
Homeopathic andHomotoxicological
Remedies
Vit iMinerals,
,
, COPPER GLUCONATE 4X
NATRUM PYRUVICUM 3X
ACIDUM CITRICUM 3X
SUPPORT
Proteinsynthesis
Antioxidative
Oligonutrients
Cytokines,
Trace elements
Vitamins,
, protectiony
HomeopathicNeurotransmitters
Hormones,
• P.N.E.I. REBALANCE
ANTI IL 1 4C TGF β 1 4C IL 10 4C
4
ANTI-IL 1 4C TGF- β 1 4C IL 10 4C
MELATONINE 6X β-ENDORPHIN 6X HYPOPHYSIS 200X
PINEAL GLAND 6X© Dipartimento Scientifico Guna S.p.a
GUNAGUNA®®--MATRIX MATRIX dropsdrops
• DRAINAGE- PYROGENIUM 12X
• SYMPTOMS CONTROL
- FUCUS 3X- THUJA 8X- NATRUM SULFURICUM 8X- CONJUNCTIVA TISSUE 6X- LYMPHATIC VESSELS 6X
Modulating local or systemicphlogosisinflammation
H thi dClassic
C SS S 6- HYALURONIDASE 6X
• CELL • CELL
Homeopathic andHomotoxicological
RemediesMinerals,
METABOLIC SUPPORT
- ASCORBIC ACID 2X
CELL NUTRITIONAL
SUPPORTTYROSINE 2X
Oligonutrients
Cytokines,
Trace elements
Vitamins,
, ,
ASCORBIC ACID 2X
- KREBS CYCLECATALYSTS 6X
- TYROSINE 2X
- PHENYALANINE 2X
- HISTIDINE 2X
Cytokines,
HomeopathicNeurotransmitters
Hormones,
• P.N.E.I. REBALANCEIL 6 4C
5
- IL 6 4C
- PROLACTINE 6X
- DHEA 6X© Dipartimento Scientifico Guna S.p.a.
R d i f l l
MyosotisEquisetumHydrocotileTaraxacum
D-L Malic Ac./Fumaricum Ac./Pyruvicum Ac.Trychinoil/Natrium oxalac.
GUNAGUNA®®--LYMPHO LYMPHO dropsdrops
•Lymphagogue action and stabilization of vasal
•Reduction of local inflammation on
lymphoepithelial tissues
• Reduction of lymphatic
TaraxacumSarsaparilla
Lymphatic vesselCapillary tisssue
L-Thyroxin walls tone with consequent reduction of
exudate and lymphoedema
Reduction of lymphatic spasm on inflammatory basis with consequent
restoration of the lymphatic circulation REACTIVATION OF THE
L-ThyroxinVena
lymphatic circulation C O OLYMPHATIC
CIRCULATION
HYPERTROPHYHydrastisJ lHYPERTROPHY
AND HYPERPLASY OF LYMPHATIC
ORGANS
ANTI-INFLAMMATORY ACTIVITY ON
LYMPHOEPITELIAL TISSUES
JuglansGraphitesCalendula
PhytolaccaApis
M i h h
•Hindrance to the proliferative proneness ofl i i
STRENGHTENING OF THE IMMUNE
DEFENCE
Magnesia phosph.
proliferative proneness of lymphoepitelial tissues
•Humoral immunity stimulation and
inhibitory modulation of the excessive cell
di dMagnesium
phosphoricum
6
mediated compensatory
response
phosphoricum
Juglans regia
© Dipartimento Scientifico Guna S.p.a.
TRAUMATOLOGYTRAUMATOLOGY - MUSCULAR LESIONS1
EXTERNAL CAUSES = MUSCULAR CONTUSION acute pain, swelling, painful tumefaction,
:p ,(in case) hematoma
THERAPYTHERAPY
- GUNA®-MUSCLE AMPOULES + GUNA®-NEURAL AMPOULES- GUNA®-TRAUMA DROPS
DROPS:
10 drops 3 times a day,
- GUNA®-MATRIX DROPS- GUNA®-FLAM DROPS
p y,15 minutes before meal
INTERNAL CAUSES = MUSCLE ELONGATION – MUSCULAR CONTRACTION - STRETCHING
THERAPYTHERAPYTHERAPYTHERAPY
- GUNA®-MUSCLE AMPOULES + GUNA®-NEURAL AMPOULES
7- GUNA®-TRAUMA DROPS- GUNA®-LYMPHO DROPS
© Dipartimento Scientifico Guna S.p.a.
TRAUMATOLOGYTRAUMATOLOGY - TENDINITIS 80% in Sport Medicine
2
TENDINITIS: edema, heat, tendon stiffness• tendinitis
t d iti• tendosynovitis • tendoperiostitis• etc.
THERAPYTHERAPY
1) CALCANEAN TENDON:- GUNA®-HAND/FOOT AMPOULES
2) BICIPITAL TENDINITIS:
- GUNA®-SHOULDER AMP. + GUNA®-MUSCLE AMP.- GUNA®-MATRIX DROPS- GUNA®-FLAM DROPS
- GUNA®-FLAM DROPS- GUNA®-MATRIX DROPS
4) PUBIC PAIN:3) TENDON PAIN FROM CASTS:- GUNA®-HIP AMPOULES- GUNA®-FLAM DROPS- GUNA®-LYMPHO DROPS
- GUNA®-HANDFOOT AMPOULES- GUNA®-MATRIX DROPS- GUNA®-LYMPHO DROPS
8- GUNA®-MATRIX DROPS
© Dipartimento Scientifico Guna S.p.a.
TRAUMATOLOGYTRAUMATOLOGY - FRACTURES3
- OSTEOBIOSTM DROPSGUNA® ARTHRO DROPS
THERAPYTHERAPY- GUNA®-ARTHRO DROPS- GUNA®-MATRIX DROPS- GUNA®-FLAM DROPS
G ® O S+ GUNA®- ….. AMPOULES according to the anatomic localization(e.g. fracture of femor neck: GUNA®-HIP, fracture of hand bones: GUNA®-HANDFOOT)
- DISLOCATIONS
THERAPYTHERAPY
- GUNA®-FLAM DROPS- GUNA®-ARTHRO DROPS- GUNA®-MATRIX DROPS- GUNA®-LYMPHO DROPS - in case of shoulder dislocation: add
GUNA®-SHOULDER AMPOULES
9© Dipartimento Scientifico Guna S.p.a.
TRAUMATOLOGYTRAUMATOLOGY - PERIPHERAL NERVE LESIONS
4
THERAPYTHERAPY
- GUNA®-NEURAL AMPOULESCOMPRESSION SYNDROMES
- GUNA®-FLAM DROPS
- GUNA®-MATRIX DROPSSPRAIN SYNDROMES (BRACHIAL PLEXUS)
POSTOPERATIVE PARESIS- GUNA®-TRAUMA DROPS
- SYNDROMES DUE TO HYPEREXTENSION-HYPERFLEXION
THERAPYTHERAPY- GUNA®-NECK AMPOULES
THERAPYTHERAPY- GUNA®-THORACIC AMPOULES
- GUNA®-LUMBAR AMPOULES
10© Dipartimento Scientifico Guna S.p.a.
FIBROMYALGIAFIBROMYALGIA
Fibromyalgia is not a new syndrome but a resurrection of the old “diagnosis” fibrositis
Fibromyalgia syndrome is a very common chronic illness whose pathogenesis is reported to be poorly understood
Women are more affected than men
All races are affected
12
FIBROMYALGIAFIBROMYALGIADIAGNOSIS: the patient has to constantly experience the symptomsfor more than 3-4 months and have at least 10 Trigger Pointsgginto the 18 classical sites + disturbed sleep
Commonly associated conditions: irritable bowel syndrome, migraine,phychic depression, obstructive sleep apnoea, general fatigue
Several causes have been identified: stress, tension, chill, , , ,connective tissue diseases such as
1) osteoarthritis, nerve compression, endocrine imbalance (estrogen deficiency hypothyroidism)(estrogen deficiency, hypothyroidism)
2) traumas, repetitive strain, overuse
3) physical-mental fatigue anxiety3) physical-mental fatigue, anxiety
LAB TESTS AND X-RAY: NEGATIVE FOR SPECIFIC DIAGNOSIS
13© Dipartimento Scientifico Guna S.p.a.
THE 18 POINTS TO TESTTHE 18 POINTS TO TEST
POSITIVE POINT: needs to be painful to a of 4Kg/cm2 pressure applied by the examiner’s digit
POSITIVE POINT: needs to be painful when the applied thumb p pppressure is sufficient to blanchthe nail-bed of the doctor’s thumb when he/she pressesthumb when he/she presses firmly on the part
14© Dipartimento Scientifico Guna S.p.a.
FIBROMYALGIA SYNDROMEFIBROMYALGIA SYNDROME
LOCALLOCALTHERAPYTHERAPY
GUNA®-MUSCLE + GUNA®-NEURAL2 ampoules (4 ml) + 1 ampoule (2 ml) =2 ampoules (4 ml) + 1 ampoule (2 ml)
6 ml
INTO EACH TRIGGER POINT: 0.5 ml
TRIGGER POINTS INJECTED PER SESSION: 10 - 12
NUMBER OF SESSIONS: 8 - 10
15© Dipartimento Scientifico Guna S.p.a.
NUMBER OF SESSIONS: 8 10
FIBROMYALGIA SYNDROMEFIBROMYALGIA SYNDROME
HOMEHOMETHERAPYTHERAPY
GUNA®-FLAM DROPS 15 drops 3 times a day 9am – 3pm – 9pm
Example:
GUNA®-MATRIX DROPS 15 drops 3 times a day 9.30am – 3.30pm – 9.30pm
®GUNA®-SLEEP DROPS 15 – 20 drops a day 10.30 pm
Duration of the therapy: 2 months
16© Dipartimento Scientifico Guna S.p.a.
PRACTICAL SOLUTIONS TOPRACTICAL SOLUTIONS TOPRACTICAL SOLUTIONS TO PRACTICAL SOLUTIONS TO YOUR DAILY PRACTICE IN YOUR DAILY PRACTICE IN
GENTLE & EFFECTIVE GENTLE & EFFECTIVE PAIN MANAGEMENTPAIN MANAGEMENTPAIN MANAGEMENTPAIN MANAGEMENT
THE TOP TEN IN PAIN CONTROLTHE TOP TEN IN PAIN CONTROLTHE TOP TEN IN PAIN CONTROLTHE TOP TEN IN PAIN CONTROL
17
SYNERGISM: the remedies boost each other in a synergistic way. The global effect is higher than the single remedy effect
BALANCE: in the medicines, remedies are contained in quantities and diluitions to re-balance, without altering, the neuro-quantities and diluitions to re balance, without altering, the neuroimmune-endocrine homeostasis
COMPLETENESS: the remedies are associated so that everyCOMPLETENESS: the remedies are associated so that every step of the etiopathogenetic cascade and every possible symptomatologic expression the medicine is indicated for is considered
18© Dipartimento Scientifico Guna S.p.a.
Select application site according to Type of needle
acupuncture points, trigger points, tender points, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapictechnique.
GUNA®-NECK
Chart of area/zone connections
GUNA®-SHOULDER
GUNA®-THORACIC
GUNA®-HIP
GUNA®-LUMBAR
GUNA®-ISCHIALGUNA ISCHIAL
GUNA®-HANDFOOT
GUNA®-POLYARTHRITISJoint pain
GUNA®-MUSCLEMuscle pain
GUNA®-NEURALNerve pain
GUNAGUNA®®--NECKNECKClinical Indications
GUNAGUNA®® NECKNECKClinical Indications
Neck pain due to cartilage degenerative i l i di d ( i l t th i )cervical spine disorders (cervical osteoarthrosis)
Neck pain due to cervical muscular trigger pointspoints
Stiff neck syndromeSimple neck painp pWhiplashPostural neck acheM h i l i b l (f t j i t d )Mechanical imbalance (facet joint syndrome) Cervical spinal ligament syndrome Cervical spinal nerve root pain
23
Cervical spinal nerve root painArnold syndrome
© Dipartimento Scientifico Guna S.p.a.
Active ingredients: Cartilago suis 4X HPUS 4 parts; Anti interleukin 1 alpha 4C Antiparts; Anti interleukin 1 alpha 4C, Anti interleukin 1 beta 4C, Beta-Endorphin 4C, Magnesia phosphorica 8X HPUS NuxMagnesia phosphorica 8X HPUS, Nux vomica 10X HPUS, Picricum acidum 10X HPUS Silicea 4X HPUS 2 parts; CrotalusHPUS, Silicea 4X HPUS 2 parts; Crotalus horridus 10X HPUS, Intervertebral disk, Porcine 4X 1 partPorcine 4X 1 part.
Inactive ingredient: Sterile isotonic sodiumInactive ingredient: Sterile isotonic sodium chloride solution.
24© Dipartimento Scientifico Guna S.p.a.
• Magnesia phosphorica 12X•Picricum ac. 8X
• Crotalus horridus 10X
GUNA®-NECK
Reduction of cervical rachis pain
• Beta-Endorphin 4C • Nux vomica 10X
•• Riduzione della sintomatologia Riduzione della sintomatologia algica per UPalgica per UP--REGULATION dei REGULATION dei recettori della recettori della β––EndorfinaEndorfina
psymptomatology of
different origin:• Fibromyalgic origin (Picricum acidum)
•• Pain symptomatology reduction by Pain symptomatology reduction by means of UPmeans of UP--REGULATION ofREGULATION ofβ––Endorphin receptorsEndorphin receptors
P.N.E.I. P.N.E.I. Homeopathic Homeopathic • Spastic and/or congestive origin (Crotalus horr., Nux vomica, Magnesia phosph.)• Stimulation of osteoblasts AntiAnti--
degenerativedegenerative
antalgic coreantalgic core antalgic coreantalgic core
AntiAnti--inflammatoryinflammatory phosph.)
• Nevralgic origin (Magnesia phosph.)
Anaesthetic origin:• Picricum acidum
function and correction of articular structure pathologies
degenerative degenerative core 2core 2
inflammatory inflammatory corecore
AntiAnti--degenerative degenerative
core 1core 1 Picricum acidum
• Anti interleukin 1 alpha 4C
• Anti interleukin 1 beta 4C• Silicea 4X
• Modulation of IL1 α and IL1β pro-inflammatory activity in the trigger phase of
• Biostimulation cartilage matrix components synthesis (Cartilago)
• Cartilago suis 4X
•Intervertebral disk, Porcine 4X
25
the trigger phase of inflammation• Anti-degenerative action
(Discus intervertebralis)
© Dipartimento Scientifico Guna S.p.a.
INTERLEUKIN 1INTERLEUKIN 1
Interleukin 1 (IL 1) is a cytokine secreted by different typeInterleukin 1 (IL-1) is a cytokine secreted by different type of cells of the Immune System (macrophages, monocytes, dendritic cells, fibroblasts and endothelial cells)
IL-1 = first discovered
IL-1 has various effects on the organism both at general and localIL 1 has various effects on the organism both at general and local levelOne of these effects is to support inflammatory processes; moreover it stimulates prostaglandins production from different p g ptype of cells (muscular, epithelial, etc.), the production of other cytokines (among which IL-2) and the activation and recruitment of other cells of the Immune System:y-IL-1α-IL-1 β
Those two classes have similar activities but different structures
© Dipartimento Scientifico Guna S.p.a.
INTERLEUKIN 1INTERLEUKIN 1IL 1 IS A PIVOTAL PRO‐INFLAMMATORY CYTOKINE CENTRALLY
INVOLVED IN IMMUNE SYSTEM SYSTEMIC AND LOCAL RESPONSES
LEADING TO TYPICAL EFFECTS OF INFLAMMATIONLEADING TO TYPICAL EFFECTS OF INFLAMMATION
DYSREGULATED, PROLONGED SYNTHESIS AND RELEASE OF IL 1 IN
CHRONIC INFLAMMATORY SITUATIONS CONTRIBUTE TO A NUMBERCHRONIC INFLAMMATORY SITUATIONS CONTRIBUTE TO A NUMBER
OF DISEASES, e.g. RHEUMATOID ARTHRITIS
IL 1IL 1
ACTIVATES ACTIVATES MONOCYTES/ MONOCYTES/
MACROPHAGESMACROPHAGES
INDUCES INDUCES FIBROBLASTSFIBROBLASTS
PROLIFERATIONPROLIFERATION
ACTIVATES ACTIVATES CHONDROCYTESCHONDROCYTES
ACTIVATES ACTIVATES OSTEOBLASTSOSTEOBLASTSMACROPHAGESMACROPHAGES PROLIFERATIONPROLIFERATION
INFLAMMATIONINFLAMMATION SYNOVIAL SYNOVIAL PANNUS PANNUS
CARTILAGE CARTILAGE BREAKDOWNSBREAKDOWNS
BONE BONE RESORPTIONRESORPTION
FORMATIONFORMATION
© Dipartimento Scientifico Guna S.p.a.
Why use Anti Interleukins (1) Alpha and Beta in the pain management formulas?
Interleukins 1 (IL1α; IL1ß) are the most active primary mediators from a biological point of view, secreted by Th1 cells to induce inflammation (Phase A) by means of their own capacity to stimulate the genic expression associated with the whole inflammatory process evolution
‐ Even though structurally different (codified by 2 different genes), they act on the same specific receptor. IL1 have a very short half‐life and are secreted by IL1 themselves when in contact with CD4 lymphocytesthemselves when in contact with CD4 lymphocytes
IL1 (α; ß) activate cyclooxygenase type 2 (COX2) (A), prostaglandin E2 (B) and nitric oxide (C) so activating the inflammatory process (pro‐inflammatory Interleukins)oxide (C), so activating the inflammatory process (pro‐inflammatory Interleukins)
►As a consequence, Anti Interleukins 1 (α; ß) act as NSAIDs (A), cortisone (B) and, in part, as salicylates (C), without the negative side effects caused by these allopathicpart, as salicylates (C), without the negative side effects caused by these allopathic medicines. Consequently, homeopathically diluted Anti IL1 α and ß are successfully used in osteo‐arthro‐myalgic pain management therapy (according to Physiological Regulating Medicine – Guna Method)g g )
© Dipartimento Scientifico Guna S.p.a.
What is the scientific reason for using Anti Interleukins and not Interleukins having anti inflammatory properties?having anti‐inflammatory properties?
Anti inflammatory Interleukins (mainly IL10)Anti‐inflammatory Interleukins (mainly IL10) are secreted by Th2 cells after the activation of Th1 cells (Phase B of Hoff’s Commutativeof Th1 cells (Phase B of Hoff s Commutative Reaction) and, as a consequence, they act after Interleukins 1 α and ß secretion
The block of Interleukins 1 α and ß (anti) is therefore moreThe block of Interleukins 1 α and ß (anti) is therefore more effective than the stimulation of IL10
IL10 has more anti‐inflammatory action above all in chronic forms than in acute formsforms than in acute forms
© Dipartimento Scientifico Guna S.p.a.
INFLAMMATIONINFLAMMATION
PHASE A = DEVELOPMENTPHASE A = DEVELOPMENT PHASE B = RESOLUTIONPHASE B = RESOLUTION
YESYES NONO
CHRONICIZATIONCHRONICIZATIONRECOVERYRECOVERY CHRONICIZATIONCHRONICIZATIONRECOVERYRECOVERY
© Dipartimento Scientifico Guna S.p.a.
&&
inflammation reduction(mesenchyme synthesis, tissue alkalosis sympathetic tone
inflammation development(mesenchyme hydrolysis, tissue acidosis sympathetic tone pro alkalosis, sympathetic tone,
anti‐inflammatory cytokines release: IL10, TGF β 1, etc.)
acidosis, sympathetic tone, pro‐inflammatory cytokines release: IL1α, IL1β, TNFα, IL12, IL15, IL18 INF INF β)IL18, INFα, INF β)
Phase A can last some hours‐days (acute inflammation: inflammation; sub acute inflammation; inflammation plus; chronic inflammation)
The duration of Phase A depends upon: 1) damage level2) patient’s immunoregulation) li d i f h h3) quality and quantity of the therapy
© Dipartimento Scientifico Guna S.p.a.
ENDORPHINENDORPHINENDORPHINENDORPHIN
Endorphins are organic chemical substances produced by the CNS having antipain andproduced by the CNS, having antipain and physiological characteristics similar to those of morphine and opium – however they haveof morphine and opium – however they have a wider range
Endorphins, like a number of morphinic origin alkaloids can cause states of euphoriaorigin alkaloids, can cause states of euphoria and somnolence according to the quantity releasedreleased
© Dipartimento Scientifico Guna S.p.a.
Physiological Regulating Medicine Physiological Regulating Medicine in Pain Managementin Pain Management
Homeopathic microdoses:p• guarantee lack of negative side-
ff teffects • avoid troubles concerning toleranceavoid troubles concerning tolerance• avoid pharmacological catabolites
overload in extracellular matrix and organsorgans
© Dipartimento Scientifico Guna S.p.a.
Most common combinations:
Guna®-Neck + Guna®-Muscle: neck pain due to cervical trigger points muscle-Guna -Neck + Guna -Muscle: neck pain due to cervical trigger points, muscle-tensive occipital frontal headache, whiplash.
Guna®-Neck + Guna®-Neural: brachialgia from cervical arthrosis, cranic neuritisGuna Neck Guna Neural: brachialgia from cervical arthrosis, cranic neuritis caused by atlo-epistrophic dislocation, muscle-tensive headache, lost of physiological cervical lordosis.
Guna®-Neck + Guna®-Polyarthritis: cervical syndrome caused by rheumatoid osteoarthritis or other autoimmune diseases, cervical syndrome caused by general somatic pain.
Guna®-Neck + Guna®-Arthro: cervical arthrosis, cervical articular discomfort.
37Guna®-Neck + Guna®-Trauma: post-surgery recovery, cervical contusions in traumatology and sport medicine.
into specific and selectedGUNA®-NECK into specific and selected
local Acupuncture Points
GUNA NECK
GB 21
GV 16
GB 20 SI 10BL 10
GV 15
GB 21 SI 9
SI 10
GV 14
38
into Trigger Points and referredGUNA®-NECK into Trigger Points and referred pain zones
GUNA NECK
BL 10TP
S
BL 11
TP
SI 15
TP/SI 14
C 7 C 7
TP = Main Trigger Points and correlated Acupuncture points
39
Treatment
Standard protocol for i.m. administration:
Treatment
1 ampoule 1-3 times a week according to severity and clinical evolution.
Standard protocol according to mesotherapeutic technique using 1-2 ampoules per treatment: 2 treatments for the first 2 weeks, 1 treatment a week till pain relief (average 8-10 sessions). For chronic pathologies: continue 1 treatment a week for 1 month till pain relief, then 1
40treatment a month.
© Dipartimento Scientifico Guna S.p.a.
Type of needle
Select application site according to acupuncture points, trigger points, tender p p gg ppoints, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapic technique.
41© Dipartimento Scientifico Guna S.p.a.
GUNAGUNA®®--THORACICTHORACICGUNAGUNA®® THORACICTHORACICClinical IndicationsClinical Indications
Thoracic pain due to cartilage degenerative thoracic spine disorders (thoracicthoracic spine disorders (thoracic osteoarthrosis)
Thoracic pain due to scoliosis h i i d h i l lThoracic pain due to thoracic long muscle
trigger points Pain due to thoracic spine osteophytosis Simple posterior thoracic pain (thoracic pain
syndrome)Mechanical imbalance (costo-vertebral facet (
joint syndrome)Thoracic spinal ligament syndromeThoracic spinal nerve root pain
42
Thoracic spinal nerve root pain Pain from spinal osteoporosis
© Dipartimento Scientifico Guna S.p.a.
Active ingredients: Chininum sulphuricum 8X HPUS 4 parts; Anti interleukin 1 alpha 4C, Anti interleukin 1 beta 4C, Beta-Endorphin 4C, Calcarea phosphorica 6X HPUS, Cimicifuga racemosa 4X HPUS, Intervertebral disk, Porcine 4X, Spongia tosta 10X HPUS 2 parts; Chelidonium majus 4X HPUS, Conium maculatum 6X HPUS 1 part.
Inactive ingredient: Sterile isotonic sodium chloride solution.
43© Dipartimento Scientifico Guna S.p.a.
•Chelidonium majus 4X•Cimicifuga racemosa 4X•Conium maculatum 6X
Chi i l h i 8X
GUNA®-THORACIC
Reduction of the dorsal rachis pain
• Beta-Endorphin 4C
•Chininum sulphuricum 8X•Spongia tosta 10X
•• Riduzione della sintomatologia Riduzione della sintomatologia algica per UPalgica per UP--REGULATION dei REGULATION dei recettori della recettori della β––EndorfinaEndorfina
rachis pain symptomatology of
different origin, type and localization:
Neuro-muscular i i (Ci i if
•• Pain symptomatology reduction by Pain symptomatology reduction by means of UPmeans of UP--REGULATION ofREGULATION ofβ––Endorphin receptorsEndorphin receptors
P.N.E.I. P.N.E.I. Homeopathic Homeopathic origin(Cimicifuga,
Chininum sulph., Conium)•Spastic and/or congestive origin(Chelidonium, Spongia)•Constitutional correction of ConstitutionalConstitutional
antalgic coreantalgic core antalgic coreantalgic core
AntiAnti--inflammatoryinflammatory Spongia)
LOCALIZATIONDorsal rachis: direct, all; hepatic reflex, Chelidonium. Intercostal pain: Spongia
articular structure pathologiesConstitutional Constitutional
corecoreinflammatory inflammatory
corecoreAntiAnti--
degenerative degenerative corecore Intercostal pain: Spongia
• Anti interleukin 1 alpha 4C
• Anti interleukin 1 beta 4C• Calcarea phosphorica 6X
• Anti interleukin 1 beta 4C
•Intervertebral disk, Porcine 4X• Modulation of IL1 αand IL1 β pro-
44•Anti-degenerative and anti-neuralgic action
© Dipartimento Scientifico Guna S.p.a.
and IL1 β proinflammatory activity in the trigger phase of inflammation
Most common combinations:
Guna®-Thoracic + Guna®-Muscle: thoracic pain due to scoliosis and thoracic long muscle trigger points, pain of the deep paravertebral thoracic muscles.
Guna®-Thoracic + Guna®-Neural: intercostal pain, post-herpetic thoracic neuritis, thoracic spinal nerve root pain.
Guna®-Thoracic + Guna®-Polyarthritis: thoracic syndrome caused by rheumatoid osteoarthritis, general thoracic pain.
Guna®-Thoracic + OsteobiosTM: thoracic vertebral fractures, thoracic vertebral slow healing.
45Guna®-Thoracic + Guna®-Arthro: general thoracic osteoarthrosis.
GUNA®-THORACIC into specificGUNA THORACIC into specific
local Acupuncture Points
GB 20
BL 10BL 41 BL 13
BL 12
BL 11 Selected according to the most painful area (max 10 points each treatment)BL 41
BL 42SI 10
BL 17BL 16
BL 15
BL 14BL 13 treatment)
BL 20
BL 19BL 18
Ex YishuBL 17
GB 30
BL 21
BL 20
GB 30
46
TreatmentTreatment
Standard protocol for i.m. administration:1 ampoule 1-3 times a week according to severity and clinical evolution.
Standard protocol according to h i h i i 1 2mesotherapeutic technique using 1-2
ampoules per treatment: 2 treatments for the fi 2 k 1 k ill i li ffirst 2 weeks, 1 treatment a week till pain relief (average 8-10 sessions). F h i th l i ti 1 t t tFor chronic pathologies: continue 1 treatment a week for 1 month till pain relief, then 1 t t t th
47treatment a month.
© Dipartimento Scientifico Guna S.p.a.
Type of needle
Select application site according to acupuncture points, trigger points, tender p p gg ppoints, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapic technique.
48© Dipartimento Scientifico Guna S.p.a.
GUNAGUNA®®--LUMBARLUMBARGUNAGUNA®® LUMBARLUMBARClinical Indications
Lumbar pain due to cartilage degenerative lumbar spine disorders (lumbar and lumbar-sacral arthrosis)sacral arthrosis)
Lumbar vertebral osteophytosis Low back pain due to muscular and
t di t i i ttendinous trigger points Simple lumbar pain (low back syndrome) Weak low back syndromePostural low back acheLumbar and lumbar-sacral mechanical
imbalanceLumbar and lumbar-sacral spinal ligament
syndromeSacro-iliac syndrome
49
Sacro iliac syndrome Spinal lumbar and lumbar-sacral nerve root
pain© Dipartimento Scientifico Guna S.p.a.
Active ingredients: Alumina 8X HPUS 4 parts; Anti interleukin 1 alpha 4C, Beta-parts; Anti interleukin 1 alpha 4C, BetaEndorphin 4C, Bryonia alba 4X HPUS, Hamamelis virginiana 6X HPUS, NatrumHamamelis virginiana 6X HPUS, Natrum sulphuricum 8X HPUS, Phosphoricum acidum 6X HPUS, Sepia 4X HPUS 2 parts;acidum 6X HPUS, Sepia 4X HPUS 2 parts; Anti interleukin 1 beta 4C, Intervertebral disk, Porcine 4X 1 part.Intervertebral disk, Porcine 4X 1 part.
Inactive ingredient: Sterile isotonicInactive ingredient: Sterile isotonic sodium chloride solution.
50© Dipartimento Scientifico Guna S.p.a.
Reduction of the lumbar Reduction of the lumbar rachis pain symptomatology rachis pain symptomatology of different origin, type and of different origin, type and
localization:localization:
GUNA®-LUMBAR•Neuro-muscular origin (Bryonia, Alumina, Ac. Phosphoricum). Articular origin (Natrium sulph.)
•Beta-Endorphin 4C
•Pain symptomatology reduction by means of UP-REGULATION ofβ–Endorphin receptors
•Type – cramp-like pain (Ac. phosphoricum); muscular paresis phenomena (Alumina) P.N.E.I.P.N.E.I. β p p
•Localization – Lumbosacral rachis: direct, Hamamelis; abdominal reflex, Sepia
Antalgic coreAntalgic core
AntiAnti--HomeopathicHomeopathic
•Anti interleukin 1 alpha 4C
•Anti interleukin 1 beta 4C
inflammatory inflammatory corecore
AntiAnti
Homeopathic Homeopathic antalgic coreantalgic core
M d l ti f IL1
AntiAnti--degenerative degenerative
corecore•Bryonia 4X
•Sepia officinalis 4X•Phosphoricum ac. 6X
•Modulation of IL1 αand IL1 β pro-inflammatory activity in the trigger phase of
p•Hamamelis virginiana 6X
•Alumina 8X•Natrum sulphuricum 8X
51inflammation
•Anti-degenerative and anti-neuralgic action
Intervertebral disk, Porcine 4X
© Dipartimento Scientifico Guna S.p.a.
Most common combinations:
Guna®-Lumbar + Guna®-Muscle: low back pain due to muscular and tendineous trigger points, low-back pain caused by strain from prolonged stay in erect position, lumbago caused by sports training.
Guna®-Lumbar + Guna®-Ischial: sacroiliac syndrome leg neuritis sciaticGuna -Lumbar + Guna -Ischial: sacroiliac syndrome, leg neuritis, sciatic neuralgia.
Guna®-Lumbar + Guna®-Neural: low back pain, lumbar neuritis with projected pain to the lower thoracic side.
Guna®-Lumbar + Guna®-Polyarthritis: general lumbar arthrosis, sacroiliac syndrome caused by rheumatoid arthritis.syndrome caused by rheumatoid arthritis.
Guna®-Lumbar + Guna®-Arthro: lumbar arthrosis, lumbar articular discomfort.
Guna®-Lumbar + Guna®-Lympho: pre- and post-surgery recovery of a disc
52
Guna Lumbar Guna Lympho: pre and post surgery recovery of a disc hernia L4-L5, L5-S1.
GUNA®-LUMBAR into specificlocal Acupuncture PointsSelected according to the most painful area (max 10 points each
Ex Shiqizhuixia
BL 52
GV 4
BL 23
painful area (max 10 points each treatment)
BL 52
Ex Yaoyan
BL 31BL 32
GV 2BL 23
BL 24
BL 25
BL 26BL 32
BL 53
BL 33
BL 27
BL 28
BL 29
BL 30
Ex Huanzhong
BL 54
BL 30
BL 34
BL 36
GB 30
53
BL 36
BL 35
TreatmentTreatment
Standard protocol for i.m. administration:1 ampoule 1-3 times a week according to severity and clinical evolution.
Standard protocol according to h i h i i 1 2mesotherapeutic technique using 1-2
ampoules per treatment: 2 treatments for the fi 2 k 1 k ill i li ffirst 2 weeks, 1 treatment a week till pain relief (average 8-10 sessions). F h i th l i ti 1 t t tFor chronic pathologies: continue 1 treatment a week for 1 month till pain relief, then 1 t t t th
54treatment a month.
© Dipartimento Scientifico Guna S.p.a.
Type of needle
Select application site according to acupuncture points, trigger points, tender p p gg ppoints, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapic technique.
55© Dipartimento Scientifico Guna S.p.a.
GUNAGUNA®® ISCHIALISCHIALGUNAGUNA®®--ISCHIALISCHIALClinical Indications
Sciatica painSciatica painLumbar-sciatic painNerve pain in the lowerNerve pain in the lower
lumbar spine Leg nerve pain due toLeg nerve pain due to
post-surgery treatment of disk herniation L4-L5,of disk herniation L4 L5, L5-S1
Morton neuroma56
Morton neuroma
© Dipartimento Scientifico Guna S.p.a.
Active ingredients: Aconitum napellus 8X HPUS Anti interleukin 1 alpha 4C8X HPUS, Anti interleukin 1 alpha 4C, Anti interleukin 1 beta 4C, Arsenicum album 6X HPUS Beta Endorphin 4Calbum 6X HPUS, Beta-Endorphin 4C, Cimicifuga racemosa 4X HPUS, Gnaphalium polycephalum 4X HPUSGnaphalium polycephalum 4X HPUS, Lachesis mutus 8X HPUS, Rhododendron chrysanthum 6X HPUS Rhuschrysanthum 6X HPUS, Rhus toxicodendron 4X HPUS 2 parts.
Inactive ingredient: Sterile isotonic sodium chloride solution
57
sodium chloride solution.
© Dipartimento Scientifico Guna S.p.a.
• Anti interleukin 1 alpha 4C GUNA®-ISCHIAL
• Beta-Endorphin 4C • Anti interleunin 1 beta 4C
P.N.E.I. P.N.E.I. AntiAnti--
inflammatoryinflammatory
•• Pain symptomatology Pain symptomatology reduction by means of UPreduction by means of UP--REGULATION of REGULATION of β––Endorphin Endorphin
tt
• Modulation of IL1 α and IL1 β pro-inflammatory activity in the trigger phase of inflammation
antalgic coreantalgic coreinflammatory inflammatory
corecore
Primary Primary neuralgic painneuralgic pain
receptorsreceptors
•Lachesis mutus 8X
• Modulation of abdominal wall reflexed sciatic pain (Lachesis) Reflexed Reflexed
neuralgicneuralgic neuralgic painneuralgic pain
Secondary Secondary neuralgic painneuralgic pain
•Lachesis mutus 8X •Gnaphalium polycephalum 4X
•Arsenicum album 6X •Rhododendron chrysantum 6X
e e ed sc at c pa ( ac es s)and iliac-sacral lumbar pain (Cimicifuga)
neuralgic neuralgic painpain
Modulation of sciatic pain
•Aconitum napellus 8X
• Cimicifuga 4X
• Lachesis mutus 8X pby means of inflammation neurogen phase inhibition (Aconitum and Arsenicum)and direct action on the sciatic nerve
• Pain modulation by means of a reduction in the progression of osteochondrosis
•Cimicifuga 4X
•Rhus toxicodendron 4X
58
(Gnaphalium)of osteochondrosis (Cimicifuga), coxo-femoral arthrosis(Rhus tox.), backache (Rhus tox). © Dipartimento Scientifico Guna S.p.a.
Most common combinations:
Guna®-Ischial + Guna®-Lumbar: Sacroiliac syndrome, leg neuritis, sciatic neuralgia.
Guna®-Ischial + Guna®-Neural: Leg neuritis and sciatic neuralgia in hyper acute phasehyper-acute phase.
Guna®-Ischial + Guna®-Flam: decongesting action of the leg nervesGuna®-Ischial + Guna®-Flam: decongesting action of the leg nerves, especially at the level of the vasa nervorum.
59
GUNA®-ISCHIAL into specific and selectedGUNA ISCHIAL into specific and selected
local Acupuncture PointsGB 30GB 30
BL 36
BL 37
BL 40BL 40
BL 39
BL 57
BL 58
60BL 60
TreatmentTreatment
Standard protocol for i.m. administration:1 ampoule 1-3 times a week according to severity and clinical evolution.
Standard protocol according to h i h i i 1 2mesotherapeutic technique using 1-2
ampoules per treatment: 2 treatments for the fi 2 k 1 k ill i li ffirst 2 weeks, 1 treatment a week till pain relief (average 8-10 sessions). F h i th l i ti 1 t t tFor chronic pathologies: continue 1 treatment a week for 1 month till pain relief, then 1 t t t th
61treatment a month.
© Dipartimento Scientifico Guna S.p.a.
Type of needle
Select application site according to acupuncture points, trigger points, tender p p gg ppoints, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapic technique.
62© Dipartimento Scientifico Guna S.p.a.
GUNAGUNA®®--SHOULDERSHOULDERGUNAGUNA®® SHOULDERSHOULDERClinical Indications
S l h l i th itiScapular-humeral peri-arthritis
Shoulder pain
Shoulder-arm syndrome
F h ldFrozen shoulder
Shoulder pain due to dislocation, therapeutic rest
Epicondylitis
63© Dipartimento Scientifico Guna S.p.a.
Active ingredients: Argentum nitricum 8X HPUS 4 parts; Anti interleukin 1 alpha 4C, Anti interleukin 1 beta 4C, Beta-Endorphin 4C, Cartilago suis 4X HPUS, Ferrum phosphoricum 8X HPUS, Sanguinaria canadensis 8X HPUS, Tendon, Porcine 6X 2 parts; Iris versicolor 8X HPUS, Ranunculus bulbosus 10X HPUS 1 part.
Inactive ingredient: Sterile isotonic sodium chloride solution.
64© Dipartimento Scientifico Guna S.p.a.
Reduction of shoulder pain of Reduction of shoulder pain of different origin and type:different origin and type:
• Neuralgic origin (Argentum
GUNA®-SHOULDER• Neuralgic origin (Argentum nitricum, Ferrum phosph., Iris)• Muscular origin (Ranunculus, Sanguinaria)
•Beta-Endorphin 4C
• Pain symptomatology reduction by means of UP-REGULATION of β–Endorphin receptors
( , g )
• Acute pain (Ferrum, Iris)• Chronic pain (Argentum nitricum Ranunculus) P.N.E.I.P.N.E.I. p pnitricum, Ranunculus) P.N.E.I. P.N.E.I.
antalgic coreantalgic core
AntiAnti--HomeopathicHomeopathic
•Anti interleukin 1 alpha 4C
•Anti interleukin 1 beta 4C
inflammatory inflammatory corecore
AntiAnti--
Homeopathic Homeopathic antalgic coreantalgic core
•Argentum nitricum 8X
•Ferrum phosphoricum 8X
M d l ti f IL1
degenerative degenerative corecore
Ferrum phosphoricum 8X
•Iris versicolor 8X
•Sanguinaria canadensis 8X
• Ranunculus bulbosus 10X• Modulation of IL1 αand IL1 β pro-inflammatory activity in the trigger phase of •Cartilago suis 4X
65inflammation
• Anti-degenerative and chronic anti-inflammatory action (Tendon, Porcine)
go su s•Tendon, Porcine 6X
© Dipartimento Scientifico Guna S.p.a.
Most common combinations:
Guna® Shoulder + Guna® Polyarthritis: scapulohumeral syndrome caused byGuna®-Shoulder + Guna®-Polyarthritis: scapulohumeral syndrome caused by rheumatoid arthritis or other autoimmune diseases, scapulohumeral periarthritis caused by excessive articular use.
Guna®-Shoulder + Guna®-Muscle: scapulohumeral syndrome by muscle and tendon trigger points of the supraspinatus muscle (80% of the cases), para-scapular muscles and trapezius.
Guna®-Shoulder + Guna®-Neural: epicondylitis, referred pain of the scapulohumeral syndrome along the arm and in the muscle districts nearby.
G ® Sh ld G ® T h ld i d di l iGuna®-Shoulder + Guna®-Trauma: shoulder pain due to dislocation or traumatism.
Guna®-Shoulder + Guna®-Flam: frozen shoulder, scapulohumeral periarthritis in
66
Guna Shoulder Guna Flam: frozen shoulder, scapulohumeral periarthritis in hyper-acute phase.
GUNA®-SHOULDER into specific and selectedGUNA SHOULDER into specific and selected
local Acupuncture PointsShoulderShoulder
LI 16
LI 15 LU 2
Ex Jianneiling
LI 14GB 20
GV 16BL 10
Ex JianquianEx Jianzhong
LI 11
GB 21
LI 16
TE 14
BL 10
GV 14
SI 12TE 14
SI 10
SI 9TE 13
SI 11
67
TE 13LI 14
GUNA®-SHOULDER into Trigger Points
and referred pain zonesTP/TE 14
TP/SI 13TP/SI 12
ShoulderTP
BL 43
SI 11TPD4
TP/SI 10TP/SI 10
TP/SI 9TP/Ex
Jianneiling TP = Main Trigger Points and correlated Acupuncture points
68
Acupuncture points
GUNA®-SHOULDER into specific and selectedGUNA SHOULDER into specific and selected
local Acupuncture PointsElbowElbow
LI 12
LI 11
LI 8LI 10
TE 10
SI 8
SI 7
TE 4
TE 5
Ex Quyahgwei
TE 4
LU 5 HT 3
PC 3
SI 4HT 5HT 4
HT 4
SI 7
70
HT 4
HT 5
SI 8 HT 3
GUNA®-SHOULDER into Trigger Points gg
and referred pain zones
ElbowLU 5
TP
TP
SI 8
TE 9
TP = Main Trigger Points and correlated
71
and correlated Acupuncture points
TreatmentTreatment
Standard protocol for i.m. administration:1 ampoule 1-3 times a week according to severity and clinical evolution.
Standard protocol according to h i h i i 1 2mesotherapeutic technique using 1-2
ampoules per treatment: 2 treatments for the fi 2 k 1 k ill i li ffirst 2 weeks, 1 treatment a week till pain relief (average 8-10 sessions). F h i th l i ti 1 t t tFor chronic pathologies: continue 1 treatment a week for 1 month till pain relief, then 1 t t t th
73treatment a month.
© Dipartimento Scientifico Guna S.p.a.
Type of needle
Select application site according to acupuncture points, trigger points, tender p p gg ppoints, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapic technique.
74© Dipartimento Scientifico Guna S.p.a.
GUNAGUNA®®--HANDFOOTHANDFOOTGUNAGUNA HANDFOOTHANDFOOTClinical Indications
O t th iti f di it iOsteoarthritis of digits painRhizoarthrosis of the thumb
(Forestier disease)(Forestier disease)Arthrosis pain due to hammer
toeCarpal-tunnel syndrome De Quervain diseaseM t l d M t t l iMetacarpal and Metatarsal painMorton disease Rheumatoid arthritis ofRheumatoid arthritis of
hand/footHand/Foot tendon pain due to
75prolonged immobilization (tendon pain related to casts)
© Dipartimento Scientifico Guna S.p.a.
Active ingredients: Arnica montana 4X HPUS, Viola odorata 6X HPUS 4 parts; , p ;Anti interleukin 1 alpha 4C, Anti interleukin 1 beta 4C, Beta-Endorphin , p4C, Caulophyllum thalictroides 12X HPUS 2 parts; Benzoicum acidum 6X HPUS, p ; ,Cimicifuga racemosa 10X HPUS, Ledum palustre 6X HPUS, Mercurius solubilis 8X p ,HPUS 1 part.
Inactive ingredient: Sterile isotonic sodium chloride solution.
76© Dipartimento Scientifico Guna S.p.a.
• Anti interleukin 1 alpha 4C GUNA®-HANDFOOT
• Beta-Endorphin 4C • Anti interleukin 1 beta 4C
P.N.E.I.P.N.E.I.
antalgic coreantalgic coreAntiAnti--
inflammatoryinflammatory
•• Pain symptomatology Pain symptomatology reduction by means of UPreduction by means of UP--REGULATION of REGULATION of β––Endorphin Endorphin
tt
• Modulation of IL1 α and IL1 β pro-inflammatory activity in the trigger phase of inflammationantalgic coreantalgic core inflammatory inflammatory
corecore
Inflammatory Inflammatory
receptorsreceptors
• Pain modulation by means of Gout painGout painpainpain
Degenerative Degenerative painpain
•Arnica montana 4X•Caulophillum thalictroides 12X
uric acid crystals accumulation inhibition (drainage action)
pp
•Ledum palustre 6X
•Benzoicum acidum 6X
Pain modulation by means of acute inflammation phenomena – vasal in particular – inhibition (arthrosis type)P i d l ti b f
•Viola odorata 6X
•Mercurius solubilis 8X
•Cimicifuga racemosa 10X
77
(arthrosis type)• Pain modulation by means of degenerative process (arthrosis type) inhibition
•Cimicifuga racemosa 10X
© Dipartimento Scientifico Guna S.p.a.
Most common combinations:
Guna®-Handfoot + Guna®-Polyarthritis: rheumatoid arthritis and other autoimmune diseases of hands and feet.
Guna®-Handfoot + Guna®-Neural: carpal tunnel syndrome, neuritis after plaster cast removal, Morton disease, general pain of hand and foot, neuritis of hand and foot.
Guna®-Handfoot + Guna®-Lympho: carpal tunnel syndrome, post surgery recovery.
Guna®-Handfoot + Guna®-Trauma: before and after surgical operations of hand and foot, sports contusions.
78
GUNA®-HANDFOOT into specific and selectedGUNA HANDFOOT into specific and selected
local Acupuncture PointsSI 5 SI 4
Wrist
LI 5LI 6
PC 6
TE 4
SI 5
LU 9HT 5
PC 7
LI 5 SI 6
TE 5Ex Zhongquan
79HT 7 LI 6
gq
LI 1 TE 1
HT 9SI 1
SIFENG POINTS
HandHT 8
PC 8LU 11
PC 8 BIS
TE 3
TE 2
BAXIE POINTS
Ex Luozhen Hand
PC 7
LU 9HT 7
LI 4
TE 4
TE 3
Ex Zhongquan
PC 6 TE 5LI 2
LI 3LI 4
Zhongquan
BAXIE POINTS
LI 5
BAXIE POINTS
SI 3SI 2
SI 1
80TE 1
SI 5LU 10
SI 4
FootFootST 41
ST 42
GB 40
ST 43GB 41
GB 42
GB 43
ST 44
LR 2
LR 3
GB 43
BAFENG
BL 67
ST 45GB 44 SP 1LR 1
In particularly painful anatomic parts such as hands and foot digits, spray ethyl chloride for 2-3 seconds at a distance of
81about 20 cm before infiltrating
GUNA®-HANDFOOT into specific and selectedGUNA HANDFOOT into specific and selected
local Acupuncture PointsGB 38
GB 39
ST 41 ST 42
Ex Bafeng 3
S FootST 41
ST 43LR 3 ST 44
LR 2
LR 1
BL 59
BL 60
BL 62BL 63
BL 64 GB 42 GB 43GB 44
ST 45
SP 6BL 62 BL 64
GB 41
GB 42
BL 65
GB 43
BL 67
KI 3
GB 40
KI 4
82KI 5SP 5KI 2SP 3
SP 1
SP 2
TreatmentTreatment
Standard protocol for i.m. administration:1 ampoule 1-3 times a week according to severity and clinical evolution.
Standard protocol according to h i h i i 1 2mesotherapic technique using 1-2
ampoules per treatment: 2 treatments for the fi 2 k 1 k ill i li ffirst 2 weeks, 1 treatment a week till pain relief (average 8-10 sessions). F h i th l i ti 1 t t tFor chronic pathologies: continue 1 treatment a week for 1 month till pain relief, then 1 t t t th
83treatment a month.
© Dipartimento Scientifico Guna S.p.a.
Type of needle
Select application site according to acupuncture points, trigger points, tender p p gg ppoints, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapic technique.
84© Dipartimento Scientifico Guna S.p.a.
GUNAGUNA®®--HIPHIPClinical Indications
Hip joint osteoarthrosisHip joint osteoarthrosisHip joint capsule
inflammationinflammationHip joint rheumatoid
arthritisarthritis Hip joint pain of muscle
originorigin Hip joint pain of nerve
origin (burning hip)origin (burning hip)Hip joint pain due to
prolonged bed rest85
prolonged bed restKnee osteoarthrosis
© Dipartimento Scientifico Guna S.p.a.
Active ingredients: Arnica montana 8X HPUS 4 parts; Anti interleukin 1 alpha 4C, Anti interleukin 1 beta 4C, Beta-Endorphin 4C, Calcarea fluorica 6X HPUS, Cartilago suis 4X HPUS, Colocynthis 8X HPUS, Rhus toxicodendron 10X HPUS 2 parts; Argentum metallicum 6X HPUS, Formicum acidum 8X HPUS 1 part.
Inactive ingredient: Sterile isotonic sodium chloride solution.
86© Dipartimento Scientifico Guna S.p.a.
•Argentum metallicum 6X•Arnica montana 8X
•Colocynthis 8X
GUNA®-HIP
Reduction of hip pain
• Beta-Endorphin 4C
Colocynthis 8X•Formicum ac. 8X
• Rhus toxicodendron 10X
P.N.E.I. P.N.E.I. antalgic coreantalgic core
Homeopathic Homeopathic
•• Pain symptomatology Pain symptomatology reduction by means of UPreduction by means of UP--REGULATION of REGULATION of β––Endorphin Endorphin
tt
Reduction of hip pain symptoms of
rheumatic origin :
• Capsule (Formicum ac Argentum)antalgic coreantalgic core antalgic coreantalgic core
AntiAnti--inflammatoryinflammatoryConstitutionalConstitutional
receptorsreceptors ac., Argentum)• Tendons and ligaments (Rhus tox)• Nerves (Colocynthis)• Constitutional correction of inflammatory inflammatory
corecoreConstitutional Constitutional
corecore
AntiAnti--degenerative degenerative
corecore
• Muscles (Arnica)articular structure pathology
• Anti interleukin 1 alpha 4C
• Anti interleukin 1 beta 4C• Calcarea fluorica 6X
• Modulation of IL1 α and IL1 β pro-inflammatory activity in the trigger phase
• Biostimulation of cartilagineous matrix components synthesis ( il )
• Cartilago suis 4X
• Argentum metallicum 6X
87
of inflammation(Cartilago)
• New vessels development stimulation (Argentum)
© Dipartimento Scientifico Guna S.p.a.
Most common combinations:
Guna®-Hip + Guna®-Muscle: satellite muscles involvement in case of pre-arthrosis or hip and knee arthrosis.
Guna®-Hip + Guna®-Neural: inguinal neuritis and neuritis affecting theGuna -Hip + Guna -Neural: inguinal neuritis and neuritis affecting the upper leg, caused by hip arthrosis, burning hip, neuritis due to knee arthrosis.
Guna®-Hip + Guna®-Polyarthritis: coxarthritis due to rheumatoid arthritis and other autoimmune diseases, acute coxarthritis of sportsmen.
Guna® Hip + Guna® Arthro: hip joint osteoarthritis hip joint capsuleGuna®-Hip + Guna®-Arthro: hip joint osteoarthritis, hip joint capsule inflammation.
Guna®-Hip + Guna®-Trauma: before and after surgical operations of the
88
p g phip, pain caused by prosthesis.
GUNA®-HIP into specific and selected local Acupuncture PointsAcupuncture Points
BL 54 GB 29GB 27
GB 28
S 3
SP 12ST 30
LR 12LR 11
BL 54
GB 30GB 29
ST 31
ST 32
LR 10
SP 11
GB 31
Hip
ST 32 GB 31GB 32
BL 40LR 8
BL 40
GB 34SP 9
GB 28SP 12ST 31
GB 27
LR 11
LR 12
ST 30
89
ST 31
LR 10
GUNA®-HIP into Trigger Points and referred pain zones
TP/GB 30
TP/Ex Tunzhong
BL 54
GB 29
GB 30
TP
zones
TP
Hip
TP = Main Trigger Points
TP/GB 33ST 31
TP/GB 33
TP/SP 10
TP
90
TreatmentTreatment
Standard protocol for i.m. administration:1 ampoule 1-3 times a week according to severity and clinical evolution.
Standard protocol according to h i h i i 1 2mesotherapeutic technique using 1-2
ampoules per treatment: 2 treatments for the fi 2 k 1 k ill i li ffirst 2 weeks, 1 treatment a week till pain relief (average 8-10 sessions). F h i th l i ti 1 t t tFor chronic pathologies: continue 1 treatment a week for 1 month till pain relief, then 1 t t t th
92treatment a month.
© Dipartimento Scientifico Guna S.p.a.
Type of needle
Select application site according to acupuncture points, trigger points, tender p p gg ppoints, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapic technique.
93© Dipartimento Scientifico Guna S.p.a.
GUNAGUNA®®--POLYARTHRITISPOLYARTHRITISGUNAGUNA®® POLYARTHRITISPOLYARTHRITISClinical Indications
Small joints rheumatoid arthritis of hand and foot
Costo-sternal syndrome (Tietze syndrome)
h i l h i i dChronic polyarthritis due to auto-immune diseases (e.g. Lupus erythematosus sistemicus)erythematosus sistemicus)
Broken bone syndrome due to viral or protozoic diseasep
Joint pain due to cancer disease (chronic leukemia, monoclonal blood di )
95diseases)
© Dipartimento Scientifico Guna S.p.a.
Active ingredients: Salicylicum acidum 2X HPUS 4 parts; Aconitum napellus 6X HPUS, Anti interleukin 1 alpha 4C, Anti interleukin 1 beta 4C,
d hiBeta-Endorphin 4C, Drosera 8X HPUS, Ledum palustre 8X HPUS, Viscum
lb l hialbum 10X HPUS 2 parts; Colchicum autumnale 10X HPUS, Guaiacum 10X
SHPUS 1 part.
I i i di S il i iInactive ingredient: Sterile isotonic sodium chloride solution.
96© Dipartimento Scientifico Guna S.p.a.
GUNA®-POLYARTHRITIS
• Reduction of polyarticular pain symptomatology in acute inflammation having different
•Beta-Endorphin 4C
• Pain symptomatology reduction by means of UP-REGULATION of β–Endorphin receptors
inflammation having different localization
P.N.E.I. P.N.E.I. p pantalgic coreantalgic core
AntiAnti--Acute Acute •Salycilicum acidum 2X
•Anti interleukin 1 alpha 4C
•Anti interleukin 1 beta 4C
inflammatory inflammatory corecore
inflammatory inflammatory painpain
y
•Aconitum 6X
•Drosera 8X
•Colchicum autumnale 10X
M d l ti f IL1
Chronic Chronic inflammatory paininflammatory pain
•Guaiacum 10X
• Modulation of IL1 αand IL1 β pro-inflammatory activity in the trigger phase of
• Reduction of degenerative articular pain •Ledum palustre 8X
97inflammation
dege e a e a cu a paon a chronic-evolutive basis
•Viscum album 10X
© Dipartimento Scientifico Guna S.p.a.
Most common combinations:
Guna®-Polyarthritis + Guna®-Handfoot: rheumatoid arthritis or other autoimmune diseases of the small joints of hand and foot, metatarsalgia, metacarpalgia.
Guna®-Polyarthritis + Guna®-Neural: costosternal syndrome, in cases of presence of satellite neuritis in rheumatoid arthritis or other autoimmune diseasesdiseases.
Guna®-Polyarthritis + Guna®-Muscle: in cases of prevalence of muscle pain in rheumatoid arthritis or other autoimmune diseasesin rheumatoid arthritis or other autoimmune diseases.
Guna®-Polyarthritis + Guna®-Arthro: rheumatoid arthritis, localized or systemic arthrosis arthritis in single or several areas
98
systemic arthrosis, arthritis in single or several areas.
TreatmentTreatment
Standard protocol for i.m. administration:1 ampoule 1-3 times a week according to severity and clinical evolution.
Standard protocol according to h i h i i 1 2mesotherapeutic technique using 1-2
ampoules per treatment: 2 treatments for the fi 2 k 1 k ill i li ffirst 2 weeks, 1 treatment a week till pain relief (average 8-10 sessions). F h i th l i ti 1 t t tFor chronic pathologies: continue 1 treatment a week for 1 month till pain relief, then 1 t t t th
99treatment a month.
© Dipartimento Scientifico Guna S.p.a.
Type of needle
Select application site according to acupuncture points, trigger points, tender p p gg ppoints, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapic technique.
100© Dipartimento Scientifico Guna S.p.a.
GUNAGUNA®®--MUSCLEMUSCLEGUNAGUNA®® MUSCLEMUSCLEClinical Indications
Trigger points management: gg p gacute, subacute, chronic
Fibromyalgia syndrome
Referred somatic pain area managementg
Dermatomyositis101
y
© Dipartimento Scientifico Guna S.p.a.
Active ingredients: Arnica montana 4X HPUS Colocynthis 4X HPUS 4 parts;HPUS, Colocynthis 4X HPUS 4 parts; Belladonna 6X HPUS, Lithium benzoicum 8X HPUS Muscle tissue Porcine 4C8X HPUS, Muscle tissue, Porcine 4C, Procaine chloride 2X 2 parts; Colchicum autumnale 6X HPUS Cuprum sulphuricumautumnale 6X HPUS, Cuprum sulphuricum 4X HPUS, Hypericum perforatum 4X HPUS, Interferon gamma 4C 1 partInterferon gamma 4C 1 part.
Inactive ingredient: Sterile isotonicInactive ingredient: Sterile isotonic sodium chloride solution.
102© Dipartimento Scientifico Guna S.p.a.
GUNA®-MUSCLE•Interferon γ 4C
P i hl id 2X
•Arnica montana 4X
•Belladonna 6X
Contusive Contusive
•Procain chloride 2X
•Muscle tissue, Porcine 4CAnti-
degenerativepainpain
Spastic or Spastic or crampcramp--likelike
Muscular Muscular
degenerative core
crampcramp--like like painpain
Sprain Sprain painpain
C l hi 4X
• Colchicum autumnale 6X
•Lithium benzoicum 8X
rheumatism rheumatism
•Colocynthis 4X•Cuprum sulphuricum 4X
•Hypericum 4X
103
Hypericum 4X
© Dipartimento Scientifico Guna S.p.a.
Most common combinations:
Guna®-Muscle + Guna®-Neural: mostly combined for the specific action of muscle relaxation + nerve repolarization, fibromyalgia syndrome, muscle pain due to the nerve entrapment.
Guna®-Muscle + Guna®-Neck: all muscle pain due to cervical syndromes.
Guna®-Muscle + Guna®-Thoracic: all muscle pain due to thoracic syndromes.
Guna®-Muscle + Guna®-Lumbar: all muscle pain due to low-back syndromes.
Guna®-Muscle + Guna®-Hip: all muscle pain due to hip or knee syndromes.
Guna®-Muscle + Guna®-Shoulder: all muscle pain due to shoulder or elbow syndrome.
G ® M l G ® Fl ll l h104
Guna®-Muscle + Guna®-Flam: all muscle aches.
TreatmentTreatment
Standard protocol for i.m. administration:1 ampoule 1-3 times a week according to severity and clinical evolution.
Standard protocol according to h i h i i 1 2mesotherapeutic technique using 1-2
ampoules per treatment: 2 treatments for the fi 2 k 1 k ill i li ffirst 2 weeks, 1 treatment a week till pain relief (average 8-10 sessions). F h i th l i ti 1 t t tFor chronic pathologies: continue 1 treatment a week for 1 month till pain relief, then 1 t t t th
105treatment a month.
© Dipartimento Scientifico Guna S.p.a.
Type of needle
Select application site according to acupuncture points, trigger points, tender p p gg ppoints, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapic technique.
106© Dipartimento Scientifico Guna S.p.a.
GUNAGUNA®®--NEURALNEURALClinical Indications
Non-specific brachial painNon specific brachial painBrachial nerve pain due to cervical
entrapment Intercostal nerve pain due to thoracic
entrapmentPostherpetic neuritisPostherpetic neuritisAtypical facial neuritis (Slüder
syndrome, Charlin syndrome)syndrome, Charlin syndrome)Trigeminal neuritisPain of the temporomandibular joint
(TMJ)Arnold syndrome Cervical thoracic lumbar and
107
Cervical, thoracic, lumbar and sacrolumbar nerve root pain
© Dipartimento Scientifico Guna S.p.a.
Active ingredients: Aconitum napellus 8X HPUS, Beta-Endorphin 4C, Colocynthis 4X HPUS, Ferrum phosphoricum 2X HPUS, Formica rufa 8X HPUS, Gnaphalium polycephalum 6X HPUS, Iris versicolor 8X HPUS, Kalmia latifolia 2X HPUS, Neurotrophin 4 4C, Paris quadrifolia 6X HPUS 2 parts.
Inactive ingredient: Sterile isotonic sodium chloride solution.
108© Dipartimento Scientifico Guna S.p.a.
•Kalmia latifolia 2X
•Ferrum phosphoricum 2XGUNA®-NEURAL
• Beta-Endorphin 4C •Colocynthis 4X
•Paris quadrifolia 6X
•Gnaphalium polycephalum 6X
P.N.E.I. P.N.E.I. antalgic antalgic InflammatoryInflammatory
•• Pain symptomatology Pain symptomatology reduction by means of UPreduction by means of UP--REGULATION of REGULATION of β––Endorphin Endorphin
tt
•Iris versicolor 8X
•Aconitum napellus 8X
corecoreInflammatory Inflammatory
aetiologyaetiology
Vascular Vascular
receptorsreceptors
• Reduction of different peripheral nerves inflammationRheumatoid Rheumatoid
aetiologyaetiology
Degenerative Degenerative aetiologyaetiology
inflammation• Modulation of paresis and paralysis phenomena
aetiologyaetiology
•Formica rufa 8X
• Kalmia latifolia 2X
Reduction of pain and paraesthetic phenomena by means of hyperemetic
• Trophic action on roots and nerve endings damaged
•Neurotrophin 4 4C
109
y ypaction on nerves
e e e d gs da agedbecause of degenerative or lesionary phenomena
© Dipartimento Scientifico Guna S.p.a.
Infiltration points for trigeminal paintrigeminal pain
Infiltration points for Charlin andCharlin and Slüdersyndromes
110pain
© Dipartimento Scientifico Guna S.p.a.
Most common combinations:
Guna®-Neural + Guna®-Muscle: mostly combined for the specific action onGuna -Neural + Guna -Muscle: mostly combined for the specific action on nerve repolarization + muscle relaxation, fibromyalgia syndrome, muscle pain due to the nerve entrapment.
G ® N l + G ® N k ll l i d t i l dGuna®-Neural + Guna®-Neck: all neural pain due to cervical syndromes.
Guna®-Neural + Guna®-Thoracic: all neural pain due to thoracic syndromes.
Guna®-Neural + Guna®-Lumbar: all neural pain due to low-back syndromesGuna®-Neural + Guna®-Lumbar: all neural pain due to low-back syndromes.
Guna®-Neural + Guna®-Hip: all neural pain due to hip or knee syndromes.
Guna®-Neural + Guna®-Shoulder: all neural pain due to shoulder or elbowGuna Neural Guna Shoulder: all neural pain due to shoulder or elbow syndromes.
Guna®-Neural + Guna®-Ischial: neuritis of the leg and sciatic neuralgia in hyperacute phase
111
hyperacute phase.
Guna®-Neural + Guna®-Flam: all nerve aches.
TreatmentTreatment
Standard protocol for i.m. administration:1 ampoule 1-3 times a week according to severity and clinical evolution.
Standard protocol according to h i h i i 1 2mesotherapeutic technique using 1-2
ampoules per treatment: 2 treatments for the fi 2 k 1 k ill i li ffirst 2 weeks, 1 treatment a week till pain relief (average 8-10 sessions). F h i th l i ti 1 t t tFor chronic pathologies: continue 1 treatment a week for 1 month till pain relief, then 1 t t t th
112treatment a month.
© Dipartimento Scientifico Guna S.p.a.
Type of needle
Select application site according to acupuncture points, trigger points, tender p p gg ppoints, referred pain zones, nerve key points, Head zones or “local pain points”. Using a 13 mm 30G, a 4 mm 27G, or an insulin needle, make the classic intradermal or subcutaneous injection according to mesotherapic technique.
113© Dipartimento Scientifico Guna S.p.a.