PRESENTATION BY:BRADLEY PELHAM CO - INVESTIGATOR

SAMANTHA YEE COLLAB ORATORDANNIE ZHABILOV PRINC IPAL

INVESTIGATOR

Envelope Glycoprotein 120 (gp120) in the Presence of Micro-Gravity

Background

•Envelope Glycoprotein• Structure• Purpose•HIV-1•Infectious process

Objective

To determine the effects of microgravity on the structure of glycoprotein 120 and whether or not the effects, if there are any, have an effect on the purpose of gp120.

Method

Design (type 1 FME)Recombinant gp120Protein folding assay

Theoretical Results

The effects of a changed protein structureThe effects on the binding of HIV-1 to T-cells

Conclusion

Open new doors for HIV-1 treatmentNew explanation to protein folding

Acknowledgements

Dr. Harry Zhabilov Nanoracks The Smithsonian Institution SSEP Mr. Wyeth Collo San Marino High School San Marino Unified School District San Marino PTSA Stephen and Mary Birch Foundation Center for the Advancement of Science in Space (CASIS), SSEP

National Partner National Center for Earth and Space Science Education Subaru of America, Inc., SSEP National Partner