ENZYMESPresented by Angie Ates BCND, CAHP-BC

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enzymes and their function

✤ No plant, animal, or human could exist without enzymes

✤ Researchers have identified more than 3,000 kinds of enzymes in the human body

✤ Enzyme marker tests are used by doctors via blood panels

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what are Enzymes anyway….

✤ Enzymes are protein-based substance found in EVERY cell of EVERY living plant, animal and the human body.

✤ They either start chemical reactions or they make them run faster.

✤ They are natural catalysts that cause a chemical change WITHOUT themselves being affected.

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✤ found in toothpaste for more cleaning power

✤ makes leaves burst into beautiful colors

✤ ripens bananas and tomatoes etc

✤ cabbage fermented becomes sauerkraut

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The Amino Acid connection

✤ Enzymes are composed of amino acids

✤ Amino acids are structural units of all protein

✤ Enzymes differ in the order and number of amino acids

✤ NINE of these amino acids cannot be made by the body and must be obtained through our diet

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Naming the Enzyme

✤ Enzymes are named for the substance or substrate that they work on and break down.

✤ The suffix “ase” is then affixed to the end of the word.

✤ Example….enzyme that breaks down protein is called protease, fat- or lipid- digesting enzymes are called lipase and etc.

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SIX classes of Enzymes

CLASS FUNCTION ______________________________________________________________

Hydrolases proteases Break down the peptide bonds in proteins. amylases Break down carbohydrates. lipases Break down fats (lipids).

Isomerases Break down the rearrangement of chemical groups within the same molecule.

Ligases Catalyze the format of the bond between 2 substrate molecules through the use of an energy source.

Lyases Split the double bonds between atoms with the accumulation or dissociation of chemical groups.

Oxidoreductases Make oxidation and execution possible.

Transferases Transfer chemical groups from one molecule to another.

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2 main Enzyme groups

✤ the 2 primary groups of training in this course are

✤ 1- Hydrolases- digestive and inflammation support

✤ 2- Oxidoredctases -our free radical fighters

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how do enzymes work

✤ most work by helping take something (bonds) apart

✤ the 3-5% that synthesize instead of breaking apart are closed anabolic enzymes vs the cleaving catabolic enzymes

✤ they are very specialized- meaning substrate specific

✤ and the are FFAASSSST…..9

all about the Co factors

✤ co factors or co enzymes must be present for the Enzymes to function (vitamins and minerals)

✤ and yet others inhibit or are competitors for enzyme function

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signs of enzyme deficiency

General symptoms of enzyme deficiency include bloating/gas, multiple food sensitivities, depression, fatigue ▪ Lipase deficiency: Fat malabsorption, greasy stool, dry skin and

hair, high cholesterol, extreme discomfort with high-fat meals, muscle spasms

▪ Protease deficiency: Low blood sugar, chronic ear infections, meat fibers in stool, bacterial/viral infections

▪ Amylase deficiency: Allergies, cold hands and feet, depression, fatigue, mood swings, neck and shoulder aches, PMS, skin problems (rashes, hives, herpes, canker sores), hot flashes

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Necessary for the breakdown of macronutrients

Insufficient enzyme secretion can cause nutrient malabsorption, digestive disturbances

▪ Amylase: Carbohydrates

▪ Proteases: Proteins

▪ Lipases: Fats ▪ Cellulase: fiber ▪ Brush border enzymes: Simple and complex

carbohydrates

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✤Bottom line - illness is the most obvious sign that one needs more enzymes

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the history there is….

✤ biblical perspective - 2 Kings 20:7

✤ Dr John Beard - Scottish physician

✤ Dr Max Wolf - father for use as systemic enzyme therapy

✤ Dr Edward Howell - father of use as Digestive Enzymes

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Other uses of Enzymes

✤ Medical Testing

✤ Pulp and Paper Industry

✤ Detergents

✤ Food Production

✤ Animal Feed

✤ and more…..15

quick review of the GI tract

✤ To extract nutrients from food

✤ to digest nutrients into units small enough to be absorbed

✤ to eliminate waste products

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the process - MOUTH

✤ must chew our food

✤ Enzyme ptyalin begins with saliva in the mouth

✤ this is amylase breaks down carbs

✤ Lysozyme, Kallikrein, Lactoferrin, Peroxidase, Growth factor - all in that same MOUTH saliva

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STOMACH- the sack

✤ lining of stomach is loaded with glands supplying hormones, hydrochloric acid, and enzymes

✤ hydrochloric acid activates pepsin (inactive form is pepsinogen) and continues to break down food to “chyme”

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Small Intestine- 3 sections

✤ TOP section = duodenum- bile and pancreatic enzymes/hormones enter here

✤ Middle section = Jejunum- Fats are absorbed here

✤ Last section = ileum - vitamin B12 absorbed here

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Large Intestine

✤ Several subsections = ascending /transverse/ descending/ sigmoid colon and rectum

✤ MAIN goal - get rid of food wastes and support with balanced intestinal flora

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Enzyme absorption- 3 ways

✤ 1- pinocytosis -a method in which whole molecules are engulfed by cells and absorbed

✤ 2- transportation to the blood stream by way of the lymphatic system

✤ 3- transcellular absorption -via peristalsis

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the Environmental Factor

✤ Food mastication brings the enzyme into contact with its substrate

✤ Body heat-enzymes work in specific heat ranges

✤ Enzymes work in specific pH ranges= Food enzymes = 3.0 to 9.0 / Animal enzymes = 7.2 - 9.0

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Enzyme deficiencies -links

✤ Hypochlorhydria - not enough hydrochloric acid

✤ Achlorhydria -No hydrochloric is made

✤ Pancreatitis / Pancreatic insufficiency

✤ Intestinal toxemia

✤ Malabsorption23

Enzyme Depleters

✤ Cooking/ Canning/ Drying/ Freezing

✤ Irradiation/ Food Additives

✤ Lifestyle choices - smoking/alcohol/drugs

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free radicals vs antioxidants

✤ Free radicals are incomplete, highly unstable, reactive compounds or molecules.

✤ Antioxidants protect the body from free- radical damage by helping the body repair cellular damage or intercepting the free radicals before they can do harm

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Enzyme 2 step program

✤ Step ONE - eliminate enzyme dead foods and lifestyle deleters

✤ Step TWO - maximize your enzyme intake via food and air

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step ONE - eliminate

✤ enzyme dead food overwork the body and stress enzyme supply

✤ this forces the pancreas and other organs to produce more enzymes in a desperate attempt to digest

✤ this creates lack of reserves for maintaining immune system, circulation etc

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step TWO - maximize intake

✤ Fresh vegetables and fruits including fiber

✤ Fermented foods - kefir/sauerkraut/miso/tempeh

✤ Sprouts/ raw honey / rejuvelac

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Enzyme sources

✤ Animal Enzymes

✤ Plant Enzymes

✤ Microbial Enzymes

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Animal Enzymes

✤ Enzymes extracted from pancreas, liver or stomach of beef, oxen and pigs

✤ Included are proteases, amylases and lipase

✤ Best known are trypsin, chymotrypsin pepsin, rennin, and pancreatin (which is combination of enzymes vs a single enzyme)

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Plant Enzymes

✤ Pineapple - bromelain

✤ Papaya - papain

✤ Fig - fiction

✤ Barley - malt diastase

✤ High Protease content -such as papaya, kiwi, figs, guava and ginger root

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Microbial enzymes

✤ a/k/a plant -derived enzymes

✤ bacterial and fungal origin-produced through fermentation using microorganisms

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Combination Enzymes

✤ Manufacturers combine different types of enzymes to increase absorption and effectiveness.

✤ Combining enzymes with nutraceuticals/botanicals which improves the absorption and bioavailability maximizing the enzyme activity and reducing the drain on the body’s own digestive enzymes

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used as Digestive Enzymes

✤ Typically see improvement within hours

✤ Combination enzymes get the best results in digestive use

✤ Using enzyme enables the body to not be strained

✤ after age 45 the ability to make hcl declines- age 65 almost absolete

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Used as Systemic Therapy

✤ a/k/a Proteolytic enzyme use

✤ have a fibrinolytic effect- which thins the blood

✤ Height, weight, age and condition being addressed will determine dosage considerations

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Systemic/ Metabolic Enzymes

✤ Must be absorbed into the blood stream to be effective

✤ Absorbed via the small intestine

✤ Taken IN BETWEEN meals as not to confuse the body’s function as a digestive enzyme

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Common disorders

✤ Pancreatitis

✤ Inflammation and Infection

✤ Decrease scar tissue formation

✤ Improve circulation

✤ Blood clotting disorder support

✤ Stimulate immune system/ lymphatic action

✤ Rash/ Hives/ Skin support

✤ and MUCH MUCH MUCH more37

side effects

✤ changes in color consistency or odor of the stool

✤ cleared from body after 24-48 hours

✤ some enzymes will store in white blood cells and liver and be used for later use systemically

✤ taking enzymes continuously will support the body to achieve wellness

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bonus……

✤ Using Functional Numbers when reading blood panels are essential when truly determining the results

✤ Blood tests are simply concentrations of dissolved substances

✤ Mindful - when there are NO further resources is when the blood panels are finally “out of range”

✤ Enzymes are LIFE39

Stress and MENT

✤ All symptoms are caused by stress:

✤ M= mechanical

✤ E= emotional source

✤ N= nutritional/ chemical

✤ T= toxin overload40

Resources

✤ The Complete Book of Enzyme Therapy by Dr Anthony Cichoke

✤ Enzymes the Fountain of Life by Lopez,Williams and Miehlke

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THANK YOU for being a part of our community..hugs

2016 copyright www.AcademyEPIC.com

Angie Ates- founder of AcademyEPIC

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