epidemiology of wolff- parkinson-white syndrome in...
TRANSCRIPT
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Epidemiology of Wolff- Parkinson-
White Syndrome in Singapore
---- A Preliminary result
Hossain SM, Bai Rong, Ching Chi
Keong, Jack Tan, Kuik Hwee Bing,
Ruth Kam, Teo Wee Siong
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Objective
To find out the age, sex and racial
distributions of WPW syndrome
among the multi-ethnic
Singapore population.
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Clinical significance of WPW
syndrome study
Associated with high frequency of
arrhythmias.
It shows bizarre and misleading
electrocardiographic pattern.
Can be cured by catheter ablation.
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12 lead ECG showing different WPW
pathway
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Manifest WPW
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Methods
A retrospective study done in all WPW syndrome
patients admitted in NHC for catheter ablation from
Oct ’1991 to Dec’03.
Statistical analysis by chi-square and cross
tabulation methods.
Accessory pathway is determined by
• History and physical examination
• Analysis of surface 12 lead ECG
• Intracardiac mapping by EPS
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Picture of normal conductive
system and wpw PATHWAY
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Cinefilms to show intracardiac
catheters
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Result
Male
N=462
Female
N=289
Total
N=751
M:F
1.6:1
Age 37±14 41±15 38±15 <0.01
Race
1) Chinese
2) Malay
3) Indian
4) Others
403
37
9
13
256
22
7
4
659
59
16
17
Single
pathway
432 273 705 (94%)
Multiple
pathway
30 16 46 (6%)
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Bar chart showing the age
distributions in Single AP
AGE_GRP
70-7960-6950-5940-4930-3920-2910-19
Pe
rce
nt
30
28
26
24
22
20
18
16
14
12
10
8
6
4
20
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Pie chart showing the percentage of the
each site in Single Accessory Pathway
3.5%
12.3%
3.0%
12.9%
68.2%
Others
Posteroseptal
Anteroseptal
Right free wall
Left free wall
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Result - Racial distribution in
single pathway
Chinese Malay Indian Others p-value
Single pathway
1) LFW
2) RFW
3) Anteroseptal
4) Posteroseptal
5) Others
422
79
21
73
21
40
4
0
10
3
11
3
0
2
0
8
5
0
2
1
>0.05
X2 5.28 -5.64 -9.92 1.59
P-value <0.05 <0.05 <0.001 >0.05
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Gender distribution in single
pathway
Male Female P-value
LFW 297 184
RFW 47 44
Anteroseptal 15 6
Posteroseptal 64 23
Others 9 16
<0.05
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Conclusion
Male suffers more from WPW syndrome .
Highest incidence observed in 3rd and 4th
decade.
In Singapore LFW also topped the list
among the WPW syndrome pathways.
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Thank you!