epithelium e-learning 11 des 09

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    Epithelial tissue(Textus epithelialis)

    E-Learning :December 10, [email protected]

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    HISTOLOGY

    Four Basic Types of Tissue

    1. Epithelial

    2. Connective

    3. Muscle

    4. Nerve

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    Includes glands and epithelium.

    Glands are secretory

    Some characteristics:1. is avascular

    2. forms a protective barrier that regulates permeability

    3. cells may show polarity

    4. regeneration (highly mitotic)5. all epithelial contact with a sheet like extracellular structure

    called the basal lamina/basal membrane

    Epithelial tissue

    Textus epithelialis)

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    1. Physical protection

    2. Control permeability

    3. Provide sensation

    4.

    Produce specialized secretions

    Functions of epithelium

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    The Polarity of Epithelial Cells

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    EPITHELIAL TISSUE

    (Textus epithelialis)

    Cells are bound tightly together

    Little extracellular materialArranged in sheets

    Cover internal and external surfaces

    Often control passage of material

    Classified by shape of cells and number of layers

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    CELL SHAPE

    Squamous shape

    * Thin, flat cells

    * Look like fried eggs

    Cubodial shape

    * square shape- cross

    section

    * 6 sided polygon- surfaceColumnar

    * Rectangular- cross section

    * Polygonal-surface view

    CELL NUMBERSimple

    * Single layer

    Stratified

    * > 2 layers

    Pseudostratified

    * Appear stratified- but not

    Transitional

    * Change shape

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    SIMPLE SQUAMOUS

    Single layer

    Squamous shape

    Lining of body cavity, lungs,blood vessels

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    STRATIFIED SQUAMOUS

    Multi layer

    Outer most layer- squamous

    cells

    Inner- cuboidal or columnar

    Lining of mouth, esophagus,

    skin

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    epithelium stratificatum

    squamosum noncornificatum

    epithelium stratificatum

    squamosum cornificatum

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    SIMPLE CUBOIDAL

    Single layer

    Cuboidal shaped

    Kidney tubules, glands

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    SIMPLE COLUMNAR

    Single layer

    Columnar shape

    Lining of digestive tract

    Modified by presence of cilia

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    PSEUDOSTRATIFIED

    COLUMNAR

    One layer

    Appears stratified-but not.

    Respiratory tract

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    the nuclei appear to lie in various layers, all cell are attached

    to basal lamina some do not reach the surface

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    Cells attach via cell adhesion molecules

    (CAM)

    Cells attach at specialized cell junctions :

    Tight junctions/zonula occludens

    zonula adherens

    Desmosomes

    Gap junctions

    List one function for each type of cell junction.

    Connections:

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    Channels are formed by pairs of adjacent connexons, which are in turn composed of

    six protein subunits that span the lipid bilayer of each cell membrane. The channel

    measures about 1.5 nm in diameter, limiting the size of the molecules that can pass

    through it. Nutrients and signal molecules may be transported between cells without

    loss of material into the intercellular space, membranes are separated by a narrow

    space or gap of about 2 nm.

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    epithelium

    transitionale

    the superficial cells are rounded

    and bulge into the lumen .

    when the epithelium is

    stretched, as when the bladder

    is full of urine, the epithelium is

    thinner than before , and the

    superficial cells become

    squamous