Generic Name Brand Name Classification Mechanism of Action Indications Adverse Reactions Nursing Considerationsesomeprazole Dosage:40 mg IVTT BIDNexium Therapeutic:AntiulcerPharmacologic:Proton pump inhibitorSuppresses the inal step in gastric aci! pro!uction b" inhibiting the #$%&$'ATPase in the gastric parietal cells( This !ecreases gastric aci! secretion()is* re!uction o NSAID'associate! gastric ulcerCNS:hea!ache+ anorexia+ conusion+ !izziness+ migraine+ sleep !isor!er+ insomnia(CV:h"pertension+ tach"car!iaGI:!iarrhea+ nausea+ latulence+ ab!ominal pain+ constipation+ melena+ ,omitingGU: !"smenorrhea+ hematuria+ c"stitis+ pol"uria -onitor or S.S o a!,erse /NS eects 0,ertigo+ agitation+ !epression1 especiall" in se,erel" ill patients( -onitor phen"toin le,els 2ith concurrent use( 3ab tests: Perio!ic li,er unction tests+ /B/+ #ct .#bg+ urinal"sis or hematuria an! proteinuria(Patient!amil" #ducation )eport an" changes in urinar" elimination such aspain or !iscomort associate! 2ith urination to ph"sician( )eport se,ere !iarrhea( Drug ma" nee! to be !iscontinue!(