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SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006 Version 5.3 Revision Date 19.06.2012

Print Date 19.09.2013

1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

1.1 Product identifiers Product name : Ethanol-d6

Product Number : 611697 Brand : Aldrich CAS-No. : 1516-08-1

1.2 Relevant identified uses of the substance or mixture and uses advised against

Identified uses : Laboratory chemicals, Manufacture of substances

1.3 Details of the supplier of the safety data sheet

Company : Sigma-Aldrich Company Ltd. The Old Brickyard NEW ROAD, GILLINGHAM Dorset SP8 4XT UNITED KINGDOM

Telephone : +44 (0)1747 833000 Fax : +44 (0)1747 833313 E-mail address : eurtechserv@sial.com

1.4 Emergency telephone number

Emergency Phone # : +44 (0)1747 833100

2. HAZARDS IDENTIFICATION

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP] Flammable liquids (Category 2)

Classification according to EU Directives 67/548/EEC or 1999/45/EC Highly flammable.

2.2 Label elements

Labelling according Regulation (EC) No 1272/2008 [CLP] Pictogram

Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. Precautionary statement(s) P210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Supplemental Hazard Statements

none

According to European Directive 67/548/EEC as amended. Hazard symbol(s)

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R-phrase(s) R11 Highly flammable. S-phrase(s) S 7 Keep container tightly closed. S16 Keep away from sources of ignition - No smoking.

2.3 Other hazards - none

3. COMPOSITION/INFORMATION ON INGREDIENTS

3.1 Substances Synonyms : Ethyl alcohol-d6,

Ethyl-d5 alcohol-d Hexadeuteroethanol

Formula : C2D6O

Molecular Weight : 52.11 g/mol

4. FIRST AID MEASURES

4.1 Description of first aid measures

General advice Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact Wash off with soap and plenty of water. Consult a physician.

In case of eye contact Flush eyes with water as a precaution.

If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed Central nervous system depression, Damage to the heart.

4.3 Indication of any immediate medical attention and special treatment needed no data available

5. FIREFIGHTING MEASURES

5.1 Extinguishing media

Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Special hazards arising from the substance or mixture Carbon oxides

5.3 Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary.

5.4 Further information Use water spray to cool unopened containers.

6. ACCIDENTAL RELEASE MEASURES

6.1 Personal precautions, protective equipment and emergency procedures Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas.

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6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).

6.4 Reference to other sections For disposal see section 13.

7. HANDLING AND STORAGE

7.1 Precautions for safe handling Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.

7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store under inert gas. hygroscopic

7.3 Specific end uses no data available

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

8.1 Control parameters

Components with workplace control parameters

Component CAS-No. Value Control parameters

Basis

[2H6]ethanol 1516-08-1 TWA 1,000 ppm 1,920 mg/m3

UK. EH40 WEL - Workplace Exposure Limits

Remarks Where no specific short-term exposure limit is listed, a figure three times the long-term exposure should be used

8.2 Exposure controls

Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Personal protective equipment

Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection impervious clothing, Flame retardant antistatic protective clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air

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respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

9. PHYSICAL AND CHEMICAL PROPERTIES

9.1 Information on basic physical and chemical properties

a) Appearance Form: liquid

b) Odour no data available

c) Odour Threshold no data available

d) pH no data available

e) Melting point/freezing point

no data available

f) Initial boiling point and boiling range

no data available

g) Flash point 14 C - closed cup

h) Evaporation rate no data available

i) Flammability (solid, gas) no data available

j) Upper/lower flammability or explosive limits

no data available

k) Vapour pressure no data available

l) Vapour density no data available

m) Relative density no data available

n) Water solubility no data available

o) Partition coefficient: n-octanol/water

no data available

p) Autoignition temperature

no data available

q) Decomposition temperature

no data available

r) Viscosity no data available

s) Explosive properties no data available

t) Oxidizing properties no data available

9.2 Other safety information no data available

10. STABILITY AND REACTIVITY

10.1 Reactivity no data available

10.2 Chemical stability no data available

10.3 Possibility of hazardous reactions no data available

10.4 Conditions to avoid Avoid moisture. Heat, flames and sparks. Extremes of temperature and direct sunlight.

10.5 Incompatible materials Oxidizing agents, Peroxides, Acids, Acid chlorides, Acid anhydrides, Alkali metals

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10.6 Hazardous decomposition products Other decomposition products - no data available

11. TOXICOLOGICAL INFORMATION

11.1 Information on toxicological effects

Acute toxicity no data available

Skin corrosion/irritation no data available

Serious eye damage/eye irritation no data available

Respiratory or skin sensitization no data available

Germ cell mutagenicity no data available

Carcinogenicity

IARC: 1 - Group 1: Carcinogenic to humans ([2H6]ethanol)

Reproductive toxicity

no data available

Specific target organ toxicity - single exposure no data available

Specific target organ toxicity - repeated exposure no data available

Aspiration hazard no data available

Potential health effects

Inhalation May be harmful if inhaled. May cause respiratory tract irritation. Ingestion May be harmful if swallowed. Skin May be harmful if absorbed through skin. May cause skin irritation. Eyes May cause eye irritation.

Signs and Symptoms of Exposure Central nervous system depression, Damage to the heart.

Additional Information RTECS: Not available

12. ECOLOGICAL INFORMATION

12.1 Toxicity no data available

12.2 Persistence and degradability no data available

12.3 Bioaccumulative potential no data available

12.4 Mobility in soil no data available

12.5 Results of PBT and vPvB assessment no data available

12.6 Other adverse effects no data available

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13. DISPOSAL CONSIDERATIONS

13.1 Waste treatment methods

Product Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.

Contaminated packaging Dispose of as unused product.

14. TRANSPORT INFORMATION

14.1 UN number ADR/RID: 1170 IMDG: 1170 IATA: 1170

14.2 UN proper shipping name ADR/RID: ETHANOL IMDG: ETHANOL IATA: Ethanol

14.3 Transport hazard class(es) ADR/RID: 3 IMDG: 3 IATA: 3

14.4 Packaging group ADR/RID: II IMDG: II IATA: II

14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no

14.6 Special precautions for user no data available

15. REGULATORY INFORMATION

This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture no data available

15.2 Chemical Safety Assessment no data available

16. OTHER INFORMATION

Further information Copyright 2012 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.