etopic pregnancy

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    y Definitiono Outside ofutere cavity

    o Pregnancy erodes into blood vassel

    o Rupture structure

    y Incidenceo 1970 4.5 per 1000

    o 1992 19.7 per 1000

    o Decreace mortality

    o 95% (tubal pregnancy)

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    y Tubal pregnancy may result in

    1. Tubal rupture with intra peritoneal hemorrhage

    2. Tubal abortion3. Tubal abortion with subsequent implantation

    y Increase resk: morbidity and mortality

    anatomic damagereduce fertility rate

    y Causes of ectopic pregnancyo History salpingitis (scar)

    o Previous ectopic pregnancy 10 foldo 35 44 year 3 fold

    o Black and hispanic women

    o Intrauterine contraception device

    o

    Previous sterilization

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    y Symptoms of ectopic pregnancy

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    Physical fending in tubal pregnancyo Normal examination (unrupture ectopic)

    o Hipovolemic shock and acute abdomeno BP Pulse

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    y Diferential diagnosiso Abortion (threadtened, complete, incomplete abortion

    o Acute and chronic salpingitis

    o Follicularorrupture corpus luteum

    o Endometrioris

    o Anexial torsion

    o Gastroenteritis, appendiatis

    y Diagnostic procedureso Pragnancy test

    - urine detecHCG as early as 14 days after conception

    - serum detecHCG as early as 5 days after conceptiono Quantitative HCG followed at 2 day intervals

    increase at least 66%

    o USG TA identify intrauterine gestation 5000 6000

    TV identify intrauterine gestation 1500 UI

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    y Diagnostic Procedures

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    y Hemogramao Leucocitosis < 20.000

    o Progesterona ( used as screening test for ectopic pragnancy)

    - Less than 6.0 ng/ml suggest a nonviable pragnancy orextrauterene

    o Curettagen of the uterine cavity

    - can rule out ectopic pregnancy- chorionic villi identifies an intrauterine location

    - Aris Stella reaction Hypersecretory endometrium ofpregnancy no only in ectopicpregnancy but also intrauterine pregnancy

    Ongoing pregnancy might be interrupted

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    o Culdo centesis

    o Laparoscopy the most accurate technique

    2 -5% misdiagnosis (extremely early)

    y Management of ectopic pregnancyo

    Conservative surgical techniques- Linear salpingostomy

    - Segmental resection

    o Traditional management

    - Salpingectomy

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    y Management of ectopic pregnancy

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    o Non surgical therapy

    - Earlyunruptered ectopic pregnancy

    - Methotrexate Oral, IM, direct injestion into the ectopic

    - Less 3.5 cmt

    - No cardiac activity

    o Followed post therapy

    -S

    erial quantitative H

    CG to monitorregression ofpregnancy

    - RH (-) (Rho GAM)

    o Combined pregnancy

    - Heterotopic pregnancy 1 in 3000 4000pregnancies

    Survival 10 20% signicont deformity

    Removal placenta not attempted

    methotrexate

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    y Cervical pregnancy

    y Ovarion pragnancy