etopic pregnancy
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y Definitiono Outside ofutere cavity
o Pregnancy erodes into blood vassel
o Rupture structure
y Incidenceo 1970 4.5 per 1000
o 1992 19.7 per 1000
o Decreace mortality
o 95% (tubal pregnancy)
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y Tubal pregnancy may result in
1. Tubal rupture with intra peritoneal hemorrhage
2. Tubal abortion3. Tubal abortion with subsequent implantation
y Increase resk: morbidity and mortality
anatomic damagereduce fertility rate
y Causes of ectopic pregnancyo History salpingitis (scar)
o Previous ectopic pregnancy 10 foldo 35 44 year 3 fold
o Black and hispanic women
o Intrauterine contraception device
o
Previous sterilization
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y Symptoms of ectopic pregnancy
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Physical fending in tubal pregnancyo Normal examination (unrupture ectopic)
o Hipovolemic shock and acute abdomeno BP Pulse
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y Diferential diagnosiso Abortion (threadtened, complete, incomplete abortion
o Acute and chronic salpingitis
o Follicularorrupture corpus luteum
o Endometrioris
o Anexial torsion
o Gastroenteritis, appendiatis
y Diagnostic procedureso Pragnancy test
- urine detecHCG as early as 14 days after conception
- serum detecHCG as early as 5 days after conceptiono Quantitative HCG followed at 2 day intervals
increase at least 66%
o USG TA identify intrauterine gestation 5000 6000
TV identify intrauterine gestation 1500 UI
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y Diagnostic Procedures
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y Hemogramao Leucocitosis < 20.000
o Progesterona ( used as screening test for ectopic pragnancy)
- Less than 6.0 ng/ml suggest a nonviable pragnancy orextrauterene
o Curettagen of the uterine cavity
- can rule out ectopic pregnancy- chorionic villi identifies an intrauterine location
- Aris Stella reaction Hypersecretory endometrium ofpregnancy no only in ectopicpregnancy but also intrauterine pregnancy
Ongoing pregnancy might be interrupted
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o Culdo centesis
o Laparoscopy the most accurate technique
2 -5% misdiagnosis (extremely early)
y Management of ectopic pregnancyo
Conservative surgical techniques- Linear salpingostomy
- Segmental resection
o Traditional management
- Salpingectomy
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y Management of ectopic pregnancy
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o Non surgical therapy
- Earlyunruptered ectopic pregnancy
- Methotrexate Oral, IM, direct injestion into the ectopic
- Less 3.5 cmt
- No cardiac activity
o Followed post therapy
-S
erial quantitative H
CG to monitorregression ofpregnancy
- RH (-) (Rho GAM)
o Combined pregnancy
- Heterotopic pregnancy 1 in 3000 4000pregnancies
Survival 10 20% signicont deformity
Removal placenta not attempted
methotrexate
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y Cervical pregnancy
y Ovarion pragnancy