EUROPEAN COORDINATION HUB AND DISTRIBUTION CENTER

End-to-End Clinical Supply Chain Management from the Heart of Europe

PAREXEL® CLINICAL RESEARCH SERVICES: CLINICAL TRIAL SUPPLIES & LOGISTICS

A WORLD CLASS COORDINATION HUB AND

DISTRIBUTION CENTER

PAREXEL’s new state-of-the art coordination hub and distribution center will help you more efficiently manage clinical supply logistics across Europe.

PAREXEL takes an integrated approach to clinical logistics to ensure clinical trial supplies, ancillary supplies, and central lab services are delivered on time and on budget.

Whether you are conducting a small regional study or undertaking a complex global trial, your presence in Europe requires a robust supply chain network that includes country-specific knowledge and a close connection to local authorities. PAREXEL provides that presence and expertise.

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PAREXEL’S EUROPEAN COORDINATION HUB AND DISTRIBUTION CENTER OFFERS CLINICAL TRIAL SUPPLIES AND LOGISTICS SERVICES DESIGNED TO REDUCE STUDY START-UP AND ACCELERATE FIRST-PATIENT-IN.

STRATEGIC SOURCING, MANUFACTURING AND PACKAGING

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Every clinical trial is unique. As a result, there is no “one-size fits all” approach to the sourcing, manufactur-ing and distribution of clinical trial supplies. From Schönefeld, PAREXEL’s Clinical Trial Supplies & Logistics group will customize a sourcing, manufacturing and distribution strategy that is efficient, robust and compliant with all local regulations across Europe.

The Coordination Hub and Distribution Center can:

• Provide local and/or central sourcing of comparator and non-investigational medicinal products

• Coordinate investigational medicinal products manufacturing through our contract manufacturing organization partners or sponsor-delegated partners to optimize material utilization, supply and re-supply strategies, expiration dates and costs

• Offer full-service and secondary clinical packaging for randomized, double-blind or two/three panel studies, as well as customized packaging design, custom secondary packaging and patient supply kits

• Develop, translate and distribute all the documen- tation for sites, investigators or patients

PAREXEL’S EUROPEAN COORDINATION HUB AND DISTRIBUTION CENTER OFFERS:

• 5,500 m2 facility offering more than 65,000 cubic meters of clinical supply storage space

• A centralized European location

• Capabilities to handle controlled substances

• “Study in a box” consolidation of clinical trial and ancillary supplies

• A space validated and inspected by the Brandenburg Ministry of Environment, Health and Consumer Protection and awarded an EU Good Manufacturing Practice certificate

• EU Gateway services and Qualified Person release

• Planning and forecasting services to optimize clinical trials supplies strategy and logistics

• Manufacturing management of investigational medicinal products and medical devices

• Clinical packaging and labeling services

• Storage, distribution, inventory control, returns and destruction and final clinical trial material reconciliation

• Global trade compliance (import/export) and regulatory support

• Supply chain visibility enabled by eLogistics technologies

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WAREHOUSING INFRASTRUCTURE AND IT SYSTEMS TO TRACK AND TRACE SHIPMENTS AND MANAGE INVENTORY LEVELS

PAREXEL’s Clinical Trials Supplies systems enable us to have the right products in the right place at the right time. Our intelligent software provides full clinical supply chain transparency, and enables us to optimize inventory control across our depot network.

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DISTRIBUTION SOLUTIONS THAT SPAN THE GLOBE

“STUDY IN A BOX” SIMPLIFIES LOGISTICS, IMPROVES INVENTORY CONTROL

PAREXEL’s European Coordination Hub and Distribution Center can consolidate all clinical trials supplies, as well as ancillary and lab supplies into a “study in a box”. Designed to reduce the risk of misplaced materials, increase inventory transparency, study in a box can significantly reduce shipping costs.

A SINGLE POINT OF CONTACT FOR ALL YOUR EUROPEAN CLINICAL LOGISTICS NEEDS

PAREXEL’s European Coordination Hub and Distribution Center is managed and staffed by PAREXEL personnel who are trained to high standards and have full under-standing of regulatory compliance.

Working with PAREXEL ensures that logistical planning and execution is integrated into the entire clinical trial process beginning with study start-up planning through the end of each study’s lifecycle.

PAREXEL’s European Coordination Hub and Distribution Center is part of our global depot network of clinical logistics facilities that can store and distribute investi- gational medicinal products, clinical trials supplies, ancillary supplies and equipment and offer sophisticated capabilities including enhanced expiry date management, packaging and labeling services, returns and destruction.

The European Coordination Hub and Distribution Center’s flexible regional distribution services can serve small regional studies and complex global trials, and can be scaled for entire development programs. Distribution is executed according to PAREXEL’s standard operating procedures, which are designed to accelerate project setup, decrease turnaround times and minimize supply chain issues.

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THE EUROPEAN COORDINATION HUB AND DISTRIBUTION CENTER EXPANDS PAREXEL’S GLOBAL CLINICAL TRIAL SUPPLIES AND LOGISTICS INFRASTRUCTURE IN NORTH AMERICA, LATIN AMERICA, EUROPE, AFRICA AND THE ASIA PACIFIC REGION.

Schönefeld

Airport

A113 North ExitSchönefeld

Thomas-Dachser Avenue

Hans-Grade Avenue

BAB 113

BAB 113

Route to EU DC via DachserEntrance 2 - Warehouse

©2014 PAREXEL International Corporation. All rights reserved.

To learn how PAREXEL’s European Coordination Hub and Distribution Center can optimize your reach in Europe, visit: www.PAREXEL.com/solutions/clinical-research/ clinical-trial-supplies-&-logistics or contact:

Tony Street Senior Director of Global Business Development Clinical Trial Supplies and Logistics +44 (0) 1895 818 960 tony.street@PAREXEL.com

Corporate Headquarters 195 West Street Waltham, MA 02451 USA +1 781 487 9900

Offices across Europe, Asia and the Americas

www.PAREXEL.com

PAREXEL’S EUROPEAN COORDINATION HUB AND DISTRIBUTION CENTER—AT THE HEART OF EUROPE

PAREXEL designed the facility in Schönefeld, Germany from the ground-up to serve as a clinical trial supplies and logistics center for all of Europe. The 5,500 m2 coordination hub and distribution center is close to Berlin’s major airports and major highway routes to ensure your clinical supplies arrive at your trial location in no more than one day.

This central location makes distribution throughout both Western and Eastern Europe easy and reduces the risk of costly clinical supply chain delays.

Address: Thomas-Dachser-Allee 1c 12529 Schönefeld Germany