experience of a nyc hospital with non-occupational post-exposure prophylaxis (npep)
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Experience of a NYC hospital with non-occupational post-exposure prophylaxis (nPEP). Antonio Urbina 1 , Georgina Osorio 1 , Daniel Egan 2 , Paul Galatowitsch 3 , Benjamen Riggan 1 ; Zachariah Hennessey 1 ; Victoria Sharp - PowerPoint PPT PresentationTRANSCRIPT
Experience of a NYC hospital with non-occupational post-exposure prophylaxis
(nPEP)Antonio Urbina1, Georgina Osorio1, Daniel Egan2, Paul
Galatowitsch3, Benjamen Riggan1; Zachariah Hennessey1; Victoria Sharp
Center for Comprehensive Care, St. Luke’s-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY, USA1; St. Luke’s-Roosevelt Hospital Center, Columbia University
College of Physicians and Surgeons, New York, NY, USA2;
Health Clear Strategies, New York, NY, USA3
Oral Abstract TUPDC0305
XIX International AIDS Conference
Washington, DC, USA
July 24, 2012
• SLR has provided nPEP in its 2 EDs and 3 outpatient HIV clinics (CCC)
• Retrospective chart review of adult patients who received nPEP from 12/2009 to 2/2012
• Demographics of patients who undertook nPEP and completed follow-up were compared
Patient presents to SLRH ED or CCC within 72 hours of
exposure to potentially HIV-infected fluid.
Baseline HIV rapid antibody testing performed with
surveillance labs. In ED, patient provided 4-day supply of nPEP with follow-up appointment to
CCC outpatient HIV clinic
Patient presents for follow-up. Provided prescription (insured)
or supply of nPEP (grant funded) to complete 28 days of treatment 2-, 4-, and 12-week
follow-up.
Background/Methods
Results Table 1. Baseline characteristics of patients
• 116/138 (84%) of patients referred to CCC completed 4-week f/u
• No significant differences seen for patients who completed nPEP
• One patient sero-converted after initiating nPEP 32 hours post exposure
Characteristic All Patients (N=216)
Patients linked to care & completed 28-day nPEP (N=116)
Mean Age – yr (range) 29.5 (18-62) 30 (18-62) Male - no. (%) 180 (83%) 92 (84%)Race/ethnicity - no. (%)
Non-Hispanic white 99 (46%) 49 (42%)Risk of HIV exposure – no. (%) men who have sex with men 139 (64%) 74 (68%)Hours from HIV exposure to presentation – hours (range)
25 (1-74) 26 (1-74)
Conclusions
• nPEP is a chemo-prophylaxis intervention that can prevent HIV acquisition and transmission and provides additional opportunities for synergistic biological and behavioral interventions.
• A multi-disciplinary approach is necessary to coordinate care, follow-up, and supportive counseling leading to successful linkage to care and completion of 28-day nPEP.
Funding: This work was supported by grants from the New York City Department of Health and Mental Hygiene and the New York State Department of Health AIDS Institute.