fatty acid & protein metabolism. carbohydrate metabolism is way groovy baby! but what does jon...
TRANSCRIPT
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Fatty Acid & Protein Metabolism
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Carbohydrate metabolism is WAY groovy baby!
But what does Jon expect us to know from all this
chemistry mumbo jumbo?
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Where is Carbohydrate Metabolism?
• Glycolysis ___________________
• Krebs Cycle ___________________
• ETS ___________________
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When Is Oxygen Required?
• Glycolysis _________________
• Krebs Cycle _________________
• ETS _________________
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What is Produced?
• Glycolysis __________________
• Krebs Cycle __________________
• ETS __________________
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Outline
I. Anaerobic Metabolism
II. Fat MetabolismA. Ketoacidosis
B. Diabetes Mellitus
III. Protein Metaboism
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Aerobic vs. Anaerobic Respiration
• Only gylcolysis can occur without O2
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Aerobic vs. Anaerobic Respiration
• Only gylcolysis can occur without O2
• Anaerobic Metabolism:
1. Inefficient and cannot be sustained for long periods
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Anaerobic Metabolism
• Occurs during strenuous exercise
• O2 cannot be delivered to cells fast enough for Krebs Cycle
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Outline
I. Anaerobic Metabolism
II. Fat MetabolismA. Ketoacidosis
B. Diabetes Mellitus
III. Protein Metaboism
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You Don’t Just Eat Carbohydrates
Big Mac Nutrition Facts:
Calories 500Protein (g) 25Carbohydrates (g) 42Total Fat (g) 26Saturated Fat (g) 16Sodium (mg) 890
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You Don’t Just Eat Carbohydrates
Big Mac Nutrition Facts:
Calories 500Protein (g) 25Carbohydrates (g) 42Total Fat (g) 26Saturated Fat (g) 16Sodium (mg) 890
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Structure of Triglycerides
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Metabolism of Fats
• Fats broken into parts that enter glycolysis and Kreb’s cycle
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Metabolism of Fats
• Fats broken into parts that enter glycolysis and Kreb’s cycle
• Fats and Carbohydrates can be stored
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You Need Some Carbs to Burn Fat
“Fats Burn in the Fire of Carbohydrate Metabolism”
2 Carbon
6 Carbon4 Carbon
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Without Glucose, Ketoacidosis Occurs
Example:Acetone
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Metabolic Disorder: Diabetes Mellitus
• Ketoacidosis occurs in Type I Diabetes
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Metabolic Disorder: Diabetes Mellitus
• Ketoacidosis occurs in Type I Diabetes
• Lack of insulin causes hyperglycemia
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Metabolic Disorder: Diabetes Mellitus
• Ketoacidosis occurs in Type I Diabetes
• Lack of insulin causes hyperglycemia
• Dehydration and sweet taste to urine
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Dangers of Ketoacidosis
• Blood pH drops
• Fruity smell to breath
• Diabetic Coma
• Death results
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Outline
I. Anaerobic Metabolism
II. Fat MetabolismA. Ketoacidosis
B. Diabetes Mellitus
III. Protein Metabolism
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Protein Metabolism
• Last resort for energy
• Why might this be?
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Protein Metabolism
• Most is converted into glucose
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Protein Metabolism
• Most is converted into glucose
• Some broken down into Urea
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Summary
• Carbohydrates, Fats, and proteins are all used for energy (in that order)
• Without oxygen, pyruvate is converted to lactate
• Ketoacidosis occurs in diabetics lacking glucose metabolism