feb 1st, 2008 gyn special edition number 2. 24 year old female. thinprep pap a.lsil b.hsil c.ascus...
TRANSCRIPT
Feb 1st, 2008
GYN SPECIAL EDITION NUMBER 2
24 year old female. ThinPrep papA. LSILB. HSILC. ASCUSD. Squamous MetaplasiaE. Endocervical Cells
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34 year old female. ThinPrep papA. Reactive endocervical cellsB. Squamous metaplasiaC. ASCUSD. LSILE. HSIL
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34 year old female. ThinPrep papA. ASCUSB. LSILC. HSILD. Squamous MetaplasiaE. Reactive/Inflammatory
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29 year old female. ThinPrep papA. Squamous metaplasiaB. Reactive endocervical cellsC. ASC-USD. LSILE. HSIL
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32 year old female. ThinPrep papA. Squamous metaplasiaB. Reactive endocervical cellsC. ASC-USD. LSILE. HSIL
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23 year old female. ThinPrep papA. Squamous metaplasiaB. ParakeratosisC. LSILD. HSILE. SCCA
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18 year old female. ThinPrep papA. CMVB. HIVC. HPVD. HSVE. EBV
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52 year old female. ThinPrep papA. Reactive endocervical cellsB. Normal endometrial cellsC. AISD. AdenocarcinomaE. HSIL
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44 year old female. ThinPrep papA. Squamous metaplasiaB. Reactive endocervical cellsC. AtrophyD. LSILE. HSIL
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34 year old female. ThinPrep papA. ReactiveB. ASCUSC. LSILD. HSILE. Squamous Metaplasia
Answers
1. D Squamous Metaplasia• Nuclei not enlarged, smooth contours, NC ratio OK. Not HSIL.
2. A Endocervical cells• Small round and regular nuclei. Compare to Ques #1.
3. E Reactive• See the trichomonas organism!
4. D LSIL• Koilocytes!
5. D LSIL• Koilocytes!
6. B Parakeratosis• Sometimes associated with dysplasia
7. D HSV• Herpes Simplex Viral changes in Nucleus
8. D Adenocarcinoma• Crowded overlapping nuclei with prominent nucleoli. No “feathering” so not Adeno in situ (AIS)
9. E HSIL• High NC ratio, irregular nuclei. This actually turned out to be a SCCA on biopsy.
10. A Reactive• No dysplasia, just some squamous cells with neutrophils.