figure e- 1 (supplemental)

2
A C Figure e-1 (supplemental) B Time (ms) Normalized gamma amplitude (%) -200 0 200 400 600 Time (ms) 0 20 40 6 0 -40 Normalized gamma amplitude (%) houses faces animals scenes objects pseudowords consonant strings scrambled images fruits (target) -20 -40 -20 0 20 40 60 -200 0 200 400 600 Figure e-1. A) Localization of the recording electrode in the 2nd patient, CQ (Talairach coordinates: -67 -44 -20) B) Mean broadband gamma response (50-150 Hz) to different stimuli. C) Trial-to-trial gamma power responses. houses faces animals scenes objects pseudowords (e.g.”boutale”) consonant strings (e.g.”qztvcw”) . scrambled images fruits (target)

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-200. 0. 200. 400. 600. Time (ms). Figure e- 1 (supplemental). A. f ruit s (t arget ). B. s crambled images. 60. c onson ant strings (e.g.”qztvcw”). 40. p seudo words (e.g.”boutale”). 20. Normalized gamma amplitude (%). o bject s. 0. s cene s. -20. a nimal s. f ace s. - PowerPoint PPT Presentation

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Page 1: Figure  e- 1  (supplemental)

A

C

Figure e-1 (supplemental)

B

Time (ms)

Nor

ma

lize

d g

amm

a a

mp

litu

de

(%)

-200 0 200 400 600

Time (ms)

0

20

40

60

-40Nor

ma

lize

d g

amm

a a

mp

litu

de

(%)

houses

faces

animals

scenes

objects

pseudowords

consonant strings

scrambled images

fruits (target)

-20

-40

-20

0

20

40

60

-200 0 200 400 600

Figure e-1. A) Localization of the recording electrode in the 2nd patient, CQ (Talairach coordinates: -67 -

44 -20) B) Mean broadband gamma response (50-150 Hz) to different stimuli. C) Trial-to-trial gamma

power responses.

houses

faces

animals

scenes

objects

pseudowords(e.g.”boutale”)

consonant strings (e.g.”qztvcw”) .

scrambled images

fruits (target)

Page 2: Figure  e- 1  (supplemental)

Figure e-2 (supplemental)

strongestresponse to:

3.5 mm

Figure e-2. Specific responses to letter-strings are confined to one electrode contact only. A)

Structural T1-weigthed MRI image of subject PM with implanted depth-electrodes. The depth-electrode

of interest is highlited by a white rectangle. B) Gamma amplitude responses to pseudowords at

neighbouring electrode contacts along the depth-electrode. Responses were normailzed to the largest

non-character response; for example, at electrode contact 7, 100% is equal response to animals, the

strongest non-character response at that electrode. Note that specific responses to letter-strings drop off

sharply from over 500% at contact 7 to 109% at contact 8. Responses of contact 7 are depicted in detail

in Figure 1. Gamma response amplitudes were calculated in a 0-200 ms window. Responses to target

images (fruits) were excluded from the figure to avoid contamination with top-down effects and motor

preparation. Electrode contacts with poor signal or no signal are omitted. Note that the size of the

electodes in A) (0.8 mm diameter) is magnified by the MRI artefact.

250

500

0

animals animalspseudo-words

pseudo-words

pseudo-words

electrodecontacts

y=-57

y=-57

z=-10

2 3 7 8 9

gamma amplitude (0-200 ms) to pseudowords

normalized to largest non-character response (%)

A

B