Seventh SICOT/SIROT Annual International Conference

&

SOF Ortopediveckan 2010

Abstracts

Oral Presentations

31 August – 3 September 2010

Swedish Exhibition & Congress Centre

Gothenburg, Sweden

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Programme – Friday, 3 September Congress Hall H1 G4 F1 F2 F4

Lecture Lecture Symposium Fragility Fractures in

Orthopaedics

08:00-09:30 Best Papers Session

Free Papers Osteoporosis

Free Papers Spine

Cervical/Lumbar Spinal Stenosis

Symposium OSOS:

Compressive osseointegration for

endoprosthetic reconstruction

Free Papers Arthroplasty

Knee

Free Papers Trauma

Pelvic Fractures

09:30-10:15 Coffee break 10:15-10:45 Plenary Lecture

Tommy Hansson

Lecture 10:45-12:15 Symposium Smoking &

Orthopaedic Surgery

Symposium Natural Disasters &

Orthopaedic Surgery

Free Papers Arthroplasty

Knee

Symposium OSOS:

Bone anchored amputation prostheses

Free Papers Trauma

Foot/Ankle

Free Papers Biomaterials/

Cartilage Repair

12:15-13:15 Closing Ceremony

Frid

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F4

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24243 TREATMENT OF COMMINUTED ACETABULAR FRACTURES USING ILIZAROV LIGAMENTOTAXIS, MINIMAL INVASIVE FIXATION AND EARLY TREATMENT OF AVASCULAR NECROSIS Nuno CRAVEIRO LOPES, Carolina ESCALDA, Carlo VILLACRESES (Portugal)

09:30-10:15 Coffee break

10:15-10:45 Plenary Lecture (in Congress Hall)

WAYS TO IMPROVE OUTCOME IN ORTHOPAEDIC SURGERY Tommy HANSSON (Sweden)

10:45-12:15 Free Papers

Biomaterials / Cartilage Repair – Free Papers

Moderators: Stephen ABELOW (United States) Per ASPENBERG (Sweden)

23978 NANOSIZED HYDROXYAPATITE AND STEM CELL COMPOSITE IN REPAIR OF RADIAL FRACTURE GAP IN RABBITS Safoora GHADIRIAN, Seifollah DEHGHANI NAZHVANI, M.A. BAHROLOLUM, G.A. GHADERI, Iman MOSTAFA (Iran)

25598 EFFECT OF HYPERBARIC OXYGEN AND COMPRESSION ON CHONDROCYTE PROLIFERATION Birte SIEVERS, Nadine HOECHSMANN, Frank DUEREN, Susanne MAYER, Peter MÜLLER (Germany)

26764 EFFECTS OF COMBINED 3D- AND HYPOXIC CULTURING ON CARTILAGE-SPECIFIC GENE EXPRESSION IN HUMAN CHONDROCYTES Casper FOLDAGER, Samir MUNIR, Michael ULRICH-VINTHER, Kjeld SØBALLE, Cody BÜNGER, Martin LIND (Denmark)

23450 BIOLOGICAL THERAPY OF BONE DEFECTS: THE IMMUNOLOGY OF BONE ALLO-TRANSPLANTATION Simon GRAHAM (United Kingdom)

26105 A BIOMIMETIC BONE SCAFFOLD FOR TISSUE ENGINEERING Prakash JAYAKUMAR, Amir BABAEI-MAHANI, B. BURANAWAT, Sanjukta DEB, Lucy DISILVIO (United Kingdom)

26041 SURFACE ENHANCED POLYETHERETHERKETONE MATERIALS FOR ORTHOPAEDIC IMPLANTATION Kelvin YEUNG, So Ching LIU, Paul CHU, Keith LUK, Kenneth CHEUNG (Hong Kong)

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Date: 2010-09-03 Session: Biomaterials / Cartilage Repair Time: 10:45-12:15 Room: F4 Abstract number: 26041 SURFACE ENHANCED POLYETHERETHERKETONE MATERIALS FOR ORTHOPAEDIC IMPLANTATION Kelvin YEUNG1, So Ching LIU1, Paul CHU2, Keith LUK1, Kenneth CHEUNG1 1The University of Hong Kong, Hong Kong (HONG KONG), 2City University of Hong Kong, Hong Kong (HONG KONG) Polyetheretherketone (PEEK) has been widely applied as bone substitute in various orthopaedic implantations. However, its bioinertness associates with the unsatisfactory bone-implant integration. Although its bioactivity can be improved by incorporating additional bioactive substance into PEEK matrix, alternation of its original mechanical properties is concerned. Alternatively, surface modification using plasma implantation has been developed in order to incorporate new biofunctional groups onto PEEK surface. This study aims at investigating the feasibility of ammonia and water plasma treatment in enhancing the surface bioactivity of PEEK. The samples measured 5mm in diameter and 3 mm thick were prepared. Water and Ammonia plasma treatments were applied at implantation energy of 10kV, 20kV and 30kV for 2 hours. Surface bioactivity assessments including cell adhesion and proliferation were conducted by using SaOs-2 cells. Alkaline phosphatase (ALP) expression and mineralization assay were applied. The minerals formed on the surfaces were qualified by energy-dispersive X-ray spectroscopy (EDX). The result of cell adhesion testing revealed that more cells attached to all the samples except NH3 10kV as compared with the untreated (p<0.05). The ALP expression of all 30kV samples was higher at Day 7 (p<0.05). However, the ALP expression and mineralization of the 30kV treated samples were not significantly different from the untreated. Apatite-like structure found on the NH3 treated surface was Ca and P rich substances. Our biological testing results suggested that the bioactivity of PEEK could be enhanced by water and ammonia plasma treatments in particular to the initial cell attachment and proliferation.