2005

Multi-membered O,N,S-heterocyclesR 0692 First Organophosphorus Radical-Mediated Cyclizations to Afford Medium-Sized

Rings: Eight-Membered Lactones and Seven- and Eight-Membered Lactams. — Diethylphosphine oxide and N-ethylpiperidine hypophosphite are reported to be effi-cient reagents for the radical cyclization of allyl-substituted aryl esters and amides to seven- and eight-membered heterocycles [cf. conditions B)—D)]. — (LANG, S.; CORR, M.; MUIR, N.; KHAN, T. A.; SCHOENEBECK, F.; MURPHY*, J. A.; PAYNE, A. H.; WILLIAMS, A. C.; Tetrahedron Lett. 46 (2005) 23, 4027-4030; Dep. Pure Appl. Chem., Univ. Strathclyde, Glasgow G1 1XL, UK; Eng.) — Mais

39- 152