food allergy in adults-the experience of a center in the north of portugal

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RESULTS Overall, 142 individuals (114 females; mean age 37±14y), with 236 suspected food adverse reacAons, were included. FAR was confirmed in 56 (24%, 43 paAents), and 105 (45%) were considered FNAR (Table 1). In 75 (32%) the study was not concluded due to paAent’s non aOendance to the OFC. INTRODUCTION It is esAmated that 23% of the adult populaAon worldwide has 1 or more food allergies but approximately 20% of the populaAon avoids certain foods because of a perceived food allergy. CONCLUSIONS Most of the adult’s adverse food reacAons in our group were not allergic, however new allergies in adults should be studied since many food allergies begin in adult age. History of anaphylaxis should not presume an allergic eAology and OFC should be carried out. Implicated foods were similar between AR and NAR, and should not alter the invesAgaAon process. Nonadherence to the diagnosAc workup should be prevented by increasing paAent awareness, avoiding unnecessary food restricAons. Poster PS04066 Food allergy in adults: the experience of a center in the North of Portugal Mariana Couto 1,2 , Alice Coimbra 1 , Diana Silva 1 , Natacha Santos 1 , Ana Pereira 1,3 , José Luís Plácido 1 1 – Serviço Imunoalergologia, Hospital São João, EPE Porto, Portugal; 2 – Immunology Lab, Faculty of Medicine, University of Porto – Porto, Portugal; 3 Health InformaAon and Decision Sciences Department Faculty of Medicine, University of Porto Porto, Portugal Allergic reacSons (n=56) Nonallergic reacSons (n = 105) p Atopy, n (%) 30 (83) 41 (63) 0.027* Asthma, n (%) 19 (54) 21 (33) 0.037* Eczema, n (%) 1 (2) 1 (1) RhiniSs, n (%) 25 (96) 36 (97) 0.799* Age of onset of symptoms, mean±SD 27±14 30±14 0.17† started in childhood, n 8 12 0.880* Reported symptoms, n (%) 0.002* Anaphylaxis 29 (54) 24 (24) Mucocutaneous symptoms 18 (32) 63 (64) Repiratory symptoms 2 (2) 4 (4) GI symptoms 4 (7) 3 (3) Onset of symptoms a\er ingesSon, n (%) <0.001* < 1h 34 (65) 33 (34) >1h 3 (6) 25 (26) Table 1: CharacterisScs of paSents and food reacSons. * Chisquare test; † Independent samples Ttest Figure 1. Food involved in allergic (A) and nonallergic reacAons (B). AIM To describe the characterisAcs, implicated foods and final allergy diagnosis among adult paAents with suspected adverse reacAons to foods and to compare food allergic reacAons (FAR) with nonallergic reacAons (FNAR). METHODS A retrospecAve analysis of clinical files of paAents followed in a University Hospital Allergy Department and referred to a Food Allergy Unit due to suspected adverse food reacAons was undertaken. Adults studied between January 2009 and October 2012 were included. Demographic characterisAcs were recorded. Final diagnosis of food allergy was based on: Clinical history sIgE skin prick tests with commercial extracts and fresh foods open food challenges (OFC) StaAsAcal analysis was perform using SPSS 18.0 (p<0.05). 0 5 10 15 20 25 30 Cow's milk Egg Fish Shellfish Fresh fruits Nuts Peanut Legumes Cephalopods % A Allergic ReacSons 0 5 10 15 20 25 30 Cow's milk Egg Fish Shellfish Fresh fruits Nuts Peanut wheat Legumes Cephalopods Others % B Nonallergic reacSons

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Page 1: Food allergy in adults-the experience of a center in the north of portugal

RESULTS  Overall,  142   individuals   (114  females;  mean  age  37±14y),  with  

236  suspected  food  adverse  reacAons,  were  included.  FAR  was  confirmed  in  56  (24%,  43  paAents),  and  105  (45%)  were  considered  FNAR  (Table  1).    

In  75  (32%)  the  study  was  not  concluded  due  to  paAent’s  non  aOendance  to  the  OFC.  

INTRODUCTION  It  is  esAmated  that  2-­‐3%  of  the  adult  populaAon  worldwide  has  1  or  more  food  allergies  but  approximately  20%  of  the  populaAon  

avoids  certain  foods  because  of  a  perceived  food  allergy.    

CONCLUSIONS  Most  of  the  adult’s  adverse  food  reacAons  in  our  group  were  not  allergic,  however  new  allergies  in  adults  should  be  studied  since  

many  food  allergies  begin  in  adult  age.    

History  of  anaphylaxis  should  not  presume  an  allergic  eAology  and  OFC  should  be  carried  out.    

Implicated  foods  were  similar  between  AR  and  NAR,  and  should  not  alter  the  invesAgaAon  process.    

Non-­‐adherence  to  the  diagnosAc  work-­‐up  should  be  prevented  by  increasing  paAent  awareness,  avoiding  unnecessary  food  restricAons.    

Poster  PS04-­‐066  

Food  allergy  in  adults:    the  experience  of  a  center  in  the  North  of  Portugal    

Mariana  Couto1,2,  Alice  Coimbra1,  Diana  Silva1,  Natacha  Santos1,  Ana  Pereira1,3,  José  Luís  Plácido1      

1  –  Serviço  Imunoalergologia,  Hospital  São  João,  EPE  -­‐  Porto,  Portugal;  2  –  Immunology  Lab,  Faculty  of  Medicine,  University  of  Porto  –  Porto,  Portugal;    3  -­‐  Health  InformaAon  and  Decision  Sciences  Department  Faculty  of  Medicine,  University  of  Porto  -­‐  Porto,  Portugal  

   Allergic  reacSons  

(n=56)  Non-­‐allergic  reacSons  

(n  =  105)  p  

Atopy,  n  (%)   30  (83)   41  (63)   0.027*    

Asthma,  n  (%)   19  (54)   21  (33)   0.037*    

Eczema,  n  (%)   1  (2)   1  (1)  

RhiniSs,  n  (%)   25  (96)   36  (97)   0.799*    

Age  of  onset  of  symptoms,  mean±SD   27±14   30±14   0.17†  

started  in  childhood,  n   8   12   0.880*    

Reported  symptoms,  n  (%)   0.002*    

Anaphylaxis   29  (54)   24  (24)  

Mucocutaneous  symptoms   18  (32)   63  (64)  

Repiratory  symptoms   2  (2)   4  (4)  

GI  symptoms   4  (7)   3  (3)  

Onset  of  symptoms  a\er  ingesSon,  n  (%)   <0.001*    

<  1h     34  (65)   33  (34)  

>1h   3  (6)   25  (26)  

Table  1:  CharacterisScs  of  paSents  and  food  reacSons.    

*  Chi-­‐square  test;  †  Independent  samples  T-­‐test  Figure  1.  Food  involved  in  allergic  (A)  and  non-­‐allergic  reacAons  (B).  

AIM  To  describe  the  characterisAcs,  implicated  foods  and  final  allergy  diagnosis  among  adult  paAents  with  suspected  adverse  reacAons  to  foods  and  to  

compare  food  allergic  reacAons  (FAR)  with  non-­‐allergic  reacAons  (FNAR).  

METHODS  A  retrospecAve  analysis  of  clinical  files  of  paAents  followed  in  a  University  Hospital  Allergy  Department  and  referred  to  a  Food  Allergy  Unit  due  to  suspected  adverse  food  reacAons  was  undertaken.    

Ø  Adults   studied   between   January   2009   and   October   2012   were  included.  

Ø  Demographic  characterisAcs  were  recorded.    

Ø  Final  diagnosis  of  food  allergy  was  based  on:          -­‐  Clinical  history  

 -­‐  sIgE  

 -­‐  skin  prick  tests  with  commercial  extracts  and  fresh  foods  

   -­‐  open  food  challenges  (OFC)  

Ø  StaAsAcal  analysis  was  perform  using  SPSS  18.0  (p<0.05).  

0  

5  

10  

15  

20  

25  

30  

Cow's  milk   Egg   Fish   Shellfish   Fresh  fruits   Nuts   Peanut   Legumes   Cephalopods  

%  

A  -­‐  Allergic  ReacSons  

0  

5  

10  

15  

20  

25  

30  

Cow's  milk   Egg   Fish   Shellfish   Fresh  fruits   Nuts   Peanut   wheat   Legumes   Cephalopods   Others  

%  

B  -­‐  Non-­‐allergic  reacSons