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For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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Page 1: For Research Use Only. Not for use in Diagnostic

For Research Use Only. Not for use in Diagnostic Procedures.US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 2: For Research Use Only. Not for use in Diagnostic
Page 3: For Research Use Only. Not for use in Diagnostic

chemagen Technology M-PVA Magnetic Beads 04chemagic Automation 06– chemagicTM 360 instrument – chemagic Magnetic Separation Module I instrument– chemagic Accessories chemagic Prepito®-D instrument 09

chemagic Kits for DNA/RNA Isolation

For use with the chemagic Automation 11For use with the chemagic Prepito®-D instrument 19For Liquid Handling 22For Manual Use 23

Page 4: For Research Use Only. Not for use in Diagnostic

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 5: For Research Use Only. Not for use in Diagnostic

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 6: For Research Use Only. Not for use in Diagnostic

Based on PerkinElmer patented magnetic bead technology, chemagic Automation instruments, with the previous developed chemagicTM 360 instrument and the well established chemagic MSM I instrument, are an ideal solution for isolating nucleic acid from a huge variety of sample materials.The instruments are used with a chemagic Rod Head chosen to support your throughput and sample volume requirements. chemagic Rod Heads areavailable for medium or high throughput DNA/RNA isolation using samplevolumes from 10 μl - 10 ml.

To meet automation needs, the systems can be extended with chemagic QASoftware and the chemagic Dispenser unit. These allow LIMS-compatible bar codereading/sample tracking and automated buffer filling for all volume applications. Due to their modular set up, chemagic Automation can be integrated with standard liquid handling units. It represents the ideal solution in a huge variety of research market segments including, but not limited to, Biobanking/Human Genetics, HLA Typing, Virus and Bacteria Detection.

The chemagic 360 instrument represents the latest version of chemagic Automation. This user friendly modular system benefits from more than 10 years’ experience with the previous well-received high throughput chemagic MSM I instrument andfacilitates high volume nucleic acid isolation within a compact benchtop system.

1 -1212

24

96

1 - 24

1 - 96

1 ml - 10 ml

200 μl - 4 ml

10 μl - 400 μl

50 ml tubes

24 single tubes,24 well plates or24 well plates XL

96 single tubes or96 well plates

e.g. for 5 ml blood~ 55 min

CMG-534

e.g. for 2 ml blood

~ 55 min CMG-535

e.g. for 10 μl blood

~ 15 min CMG-536

Key features

Sample volumes from 10 μl - 10 ml High throughput Huge kit portfolio No cross contamination Various sample materials in one run Integrates with liquid handling platforms

Benefits of the new developedchemagic 360 instrument Revolutionary compact benchtop design High volume nucleic acid isolation Convenient and improved sample management User-friendly modular system Bar code reading for sample tracking LIMS compatible log files

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 7: For Research Use Only. Not for use in Diagnostic

Use of an electro magnet to magnetize rodsThe electro magnet consists of an aluminum coil in a cover. When the power is switched on, an electric field (blue line) is generated. The electric field induces a magnetic field (red lines). The magnetic field lines are conducted through metal rods while the strongest magnetic field is at the end of the rods, which enables an efficient collection of the magnetic beads.

A chemagic Rod Head Consisting of metal rods and gearbox with motor – mounted to a linear motion system ensuring its movements up and down through the hole in the electro magnet.

B Electro Magnet Circular unit with a hole in the center.

C X-Axis Circular / linear motion axis on which all required process solutions are placed in appropriate reaction vessels.

D Integrated Screen

E Control Board With two power supplies for electro magnet and motors, motor control cards and all other electronic parts.

07

chemagic MSM I instrumentDimensions: base machine 600 x 640 x 950 mm (W/D/H); carrier axis 1940 x170 x 200 mm (W/D/H). Available with three different rod heads.

chemagicTM 360 instrument Dimensions: 800 x 800 x 900 mm (L/W/H). Available with three different rod heads.

A

B

E

D

A

BC

C

E

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 8: For Research Use Only. Not for use in Diagnostic

chemagic Dispenser unit

The use of the chemagic Automation simplifies and improvestime consuming sample preparation steps like nucleic acid isolation significantly. By using the chemagic Dispenser unit, a particularchemagic Automation add-on, sample preparation is even fasterand more comfortable. The chemagic Dispenser unit notablyreduces hands-on time when preparing a chemagic Automation run. Independent of the amount of needed buffer, the additionalunit prefills tubes/plates quickly and accurately. Variants of the chemagic Dispenser unit are available to suit the corresponding chemagic Rod Head formats (12, 24 and 96).

Features at a glance

Reduces hands-on time Simultaneous filling of up to 8 different buffers with different buffer volumes Waste of buffer is minimized Based on membrane pump technology Fully integrated in the chemagic Automation Easy upgrade of a stand-alone chemagic Automation (plug and play)

The precise technology of the chemagic Dispenser is alsointegrated in the chemagic Prepito®-D instrument.

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 9: For Research Use Only. Not for use in Diagnostic

The chemagic Prepito®-D instrument is based on chemagen‘s proven technology for magnetic particle separation and represents the top quality sample preparation system in a compact benchtop instrument.

It utilizes many years of experience in automated nucleic acid isolation gainedwith the high throughput chemagic MSM I instrument. In combination withthe PrepitoTM Kits, it delivers high yield and purity of DNA/RNA, and ensuresthe success of your downstream application.

This innovative instrument realizes cost effectiveness through automateddispensing of buffers into standard plastic devices instead of using expensiveprefilled cartridges. The chemagic Prepito-D instrument includes bar codereading and a USB port data transfer to support a high quality assurance.Hands-on time is minimized. Processing time is as short as 40 minutesfor 1 - 12 samples per batch (for e.g. 250 μl blood).

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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Total yield (µg)

7 ml

EDTA stabilized blood PAXgene stabilized blood

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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260/280

260/230

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 16: For Research Use Only. Not for use in Diagnostic

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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Selection of routinely detected Pathogens after their nucleic acid has been isolated with chemagen Technology

Adenovirus

Bordetella sp.

Chlamydophila sp.

CMV

EBV

EHEC

Enterovirus

FSME

HPV

HSV 1 / HSV 2

Influenzavirus

Legionella

Listeria

MRSA

Mycoplasma sp. (resp., std.)

Norovirus

Parvovirus

Ureaplasma sp.

VZV

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 20: For Research Use Only. Not for use in Diagnostic

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 21: For Research Use Only. Not for use in Diagnostic

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 22: For Research Use Only. Not for use in Diagnostic

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 23: For Research Use Only. Not for use in Diagnostic

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 24: For Research Use Only. Not for use in Diagnostic

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

Page 25: For Research Use Only. Not for use in Diagnostic

For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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For Research Use Only. Not for use in Diagnostic Procedures. US: For Laboratory Use Only. Not Intended For Use in Diagnostic Procedures.

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CT6521/30/1607 Printed in Germany

Copyright ©2016, PerkinElmer, Inc. All rights reserved. PerkinElmer® is a registered trademark of PerkinElmer, Inc. All other trademarks are the property of their respective owners.

PerkinElmer, Inc.940 Winter StreetWaltham, MA 02451 USAPhone: (+1) 800-762-4000or (+1) 203-925-4602www.perkinelmer.com

PerkinElmer chemagen Technologie GmbHArnold-Sommerfeld-Ring 252499 Baesweiler, GermanyPhone: (+49) 2401 805-501Fax: (+49) 2401 [email protected], www.chemagen.com