free radicals in the context of ayurvedic rejuvenative therapies presented by ingrid naiman for...

Free Radicals in the Context Free Radicals in the Context of Ayurvedic Rejuvenative of Ayurvedic Rejuvenative

Therapies Therapies

Presented by Ingrid Naiman Presented by Ingrid Naiman forfor

AAPNA on 10 March 2013AAPNA on 10 March 2013

Copyright by Dr. Ingrid Naiman 2013 Copyright by Dr. Ingrid Naiman 2013

2

Kaya KalpaKaya Kalpa

Curious about Alchemy and Curious about Alchemy and Rasayana HerbsRasayana Herbs

Fukushima RadiationFukushima Radiation Deep Concern for HumanityDeep Concern for Humanity Many Experiments & Many Experiments &

Attempts to Apply TheoriesAttempts to Apply Theories

Copyright by Dr. Ingrid Naiman 2013Copyright by Dr. Ingrid Naiman 2013

3 Copyright by Dr. Ingrid Naiman 2013Copyright by Dr. Ingrid Naiman 2013

4 Copyright by Dr. Ingrid Naiman 2013Copyright by Dr. Ingrid Naiman 2013

5

Free Radical TheoryFree Radical Theory

One Attempt to Explain the Cause of AgingOne Attempt to Explain the Cause of Aging DefinitionDefinition

Atom or molecule that has an unpaired Atom or molecule that has an unpaired electron in the outer orbitelectron in the outer orbit

ProblemsProblems Causes Oxidative Damage to TissuesCauses Oxidative Damage to Tissues Damages DNADamages DNA Kills White Blood CellsKills White Blood Cells


6

Free Radicals Associated with Free Radicals Associated with Countless Degenerative Countless Degenerative

DiseasesDiseases Occurs mainly due to damage to lipid Occurs mainly due to damage to lipid

membranemembrane MutagenicMutagenic CarcinogenicCarcinogenic

Cancer, DNACancer, DNA Heart Attacks and Strokes, LDLHeart Attacks and Strokes, LDL Everything from wrinkles to Alzheimer’s Everything from wrinkles to Alzheimer’s

disease can be attributed to free radicals.disease can be attributed to free radicals.


7

Causes of Free RadicalsCauses of Free Radicals Radiation, ionizing as well as electromagnetic fieldsRadiation, ionizing as well as electromagnetic fields Sunlight & ultraviolet light, especially UV-ASunlight & ultraviolet light, especially UV-A PollutionPollution Toxic Metals, PesticidesToxic Metals, Pesticides Chemicals & PharmaceuticalsChemicals & Pharmaceuticals OxidationOxidation

SmokingSmoking AlcoholAlcohol DietDiet


Radiation DamageRadiation Damage


9

The Vata ConnectionThe Vata Connection

Vata = Ether + AirVata = Ether + Air Associated with movement (kinetic energy)Associated with movement (kinetic energy)

Leads to changeLeads to change Can produce instabilityCan produce instability Causes sound & sensation Causes sound & sensation

Vata dosha is associated with agingVata dosha is associated with aging Vata destructiveness (wind) can cause:Vata destructiveness (wind) can cause:

Corruption of form & structureCorruption of form & structure Cell death resulting in die off debris & amaCell death resulting in die off debris & ama


10

Free Radical TheoryFree Radical Theory

Attributed to Denham Harman, 1950sAttributed to Denham Harman, 1950s Lifespan is in inverse proportion to Lifespan is in inverse proportion to

metabolic ratemetabolic rate The metabolic rate is proportional to The metabolic rate is proportional to

oxygen consumptionoxygen consumption Oxygen free radicals lead to tissue Oxygen free radicals lead to tissue

damage and ultimately deathdamage and ultimately death


11

OxidationOxidation

“ “85% of chronic and degenerative 85% of chronic and degenerative diseases are diseases are the results of oxidative damagethe results of oxidative damage.” .”

Yukie NiwaYukie Niwa


12

StressStress

Increased intake of oxygen usually results Increased intake of oxygen usually results in more free radicalsin more free radicals Inflammatory reactionInflammatory reaction

CortisolCortisol Ashwagandha lowers cortisol output Ashwagandha lowers cortisol output

even when under stresseven when under stress


13

The IronyThe Irony

Oxygen is necessary to life, but it is a Oxygen is necessary to life, but it is a highly toxic, mutagenic gashighly toxic, mutagenic gas

Oxygen is highly reactive and can cause Oxygen is highly reactive and can cause damage by producing reactive oxygen damage by producing reactive oxygen species (ROS)species (ROS)

Except for anaerobic species, most living Except for anaerobic species, most living organisms have an inherent capacity to organisms have an inherent capacity to produce antioxidantsproduce antioxidants


14

Types of Free RadicalsTypes of Free Radicals

Superoxide anion: oxygen molecule with Superoxide anion: oxygen molecule with extra electron extra electron

Hydroxyl radicalHydroxyl radical highly reactive and damages DNA, highly reactive and damages DNA,

carbohydrates, lipids, and proteins carbohydrates, lipids, and proteins Singlet oxygen, catalyst to free radical Singlet oxygen, catalyst to free radical

formation) and damages LDL cholesterolformation) and damages LDL cholesterol


15

Hydrogen PeroxideHydrogen Peroxide

Hydrogen peroxide is not a free radical but Hydrogen peroxide is not a free radical but is involved in the production of ROSis involved in the production of ROS

ROS which can persist indefinitelyROS which can persist indefinitely Highly mobileHighly mobile Penetrates the cell membrane from Penetrates the cell membrane from

outside to damage what is withinoutside to damage what is within Can form a dangerous hydroxyl free Can form a dangerous hydroxyl free

radical or be converted to water and radical or be converted to water and excreted harmlesslyexcreted harmlessly


16

Lipid Peroxidation = Lipid Peroxidation = RancidityRancidity

Affects Mainly Polyunsaturated FatsAffects Mainly Polyunsaturated Fats Processed FoodsProcessed Foods

MeatMeat CheeseCheese

Unsaturated FatsUnsaturated Fats AvocadoesAvocadoes Canola oil, olive oil, peanut oil, sunflower oilCanola oil, olive oil, peanut oil, sunflower oil Macadamia nuts, cashews, almonds, pecansMacadamia nuts, cashews, almonds, pecans


Fats in FoodFats in Food


18

Herbs to Prevent RancidityHerbs to Prevent Rancidity

Turmeric, Turmeric, Curcuma longaCurcuma longa Chaparral, Chaparral, Larrea tridentataLarrea tridentata Rosemary Essential OilRosemary Essential Oil


Hemolysis & Hemorrhage Hemolysis & Hemorrhage After Fukushima - After Fukushima -

ElectroperforationsElectroperforations


20

GheeGhee

Significant improvement in lipid structures Significant improvement in lipid structures can be expected when patients switch can be expected when patients switch from vegetable oils to gheefrom vegetable oils to ghee


21

Clinical ConsiderationsClinical Considerations

Difference between prevention and Difference between prevention and curecure ProtectiveProtective CorrectiveCorrective

ExamplesExamples ChyawanChyawan TapaswijiTapaswiji


22

ChyawanprashChyawanprash

Ancient herbal jam used to prevent aging Ancient herbal jam used to prevent aging and promote longevity, variously and promote longevity, variously attributed to the sage Chywan or the attributed to the sage Chywan or the divine Ashwini brothers.divine Ashwini brothers. Amalaki fruitAmalaki fruit Herbs & spicesHerbs & spices Ghee & sesame oilGhee & sesame oil Astavarga herbsAstavarga herbs Purified alchemical substancesPurified alchemical substances


23

Status of the PlasmaStatus of the Plasma

The plasma is straw-colored and needs to The plasma is straw-colored and needs to bebe in the correct pH rangein the correct pH range free of chemical & metallic toxins free of chemical & metallic toxins free of fungi, both yeast and moldfree of fungi, both yeast and mold free of radioactive particulates and EMF free of radioactive particulates and EMF

interferencesinterferences free of parasites, bacteria, and virusesfree of parasites, bacteria, and viruses


24

Darkfield StudiesDarkfield Studies

Observe live bloodObserve live blood Can test almost any diet or protocol to Can test almost any diet or protocol to

determine the effect on the plasmadetermine the effect on the plasma ErythrocytesErythrocytes White blood cellsWhite blood cells PlateletsPlatelets Parasites, bacteria, spirochetes, fungi, metallic toxinsParasites, bacteria, spirochetes, fungi, metallic toxins AmaAma

Presence of free radicals can be inferredPresence of free radicals can be inferred


Photoshop EnhancementPhotoshop Enhancement


TourmalineTourmaline


27

Evidence of Free RadicalsEvidence of Free Radicalsin Darkfieldin Darkfield


28

Free Radical ScavengerFree Radical Scavenger

Sometimes referred to as an antioxidantSometimes referred to as an antioxidant Renders free radical stable by donating an Renders free radical stable by donating an

electronelectron May itself become a free radicalMay itself become a free radical May be removed by white blood cellsMay be removed by white blood cells May be eliminated from the bodyMay be eliminated from the body


29

AntioxidantAntioxidant

Electron DonorElectron Donor Stabilizes the Free RadicalStabilizes the Free Radical Renders the Free Radical HarmlessRenders the Free Radical Harmless Manages these functions without sustaining Manages these functions without sustaining

damage or becoming itself a free radicaldamage or becoming itself a free radical


Electron DonationElectron Donation


31

Antioxidant HerbsAntioxidant Herbs

All Rasayana HerbsAll Rasayana Herbs ChyawanprashChyawanprash Especially high: TriphalaEspecially high: Triphala

Amalaki highestAmalaki highest HaritakiHaritaki BibhitakiBibhitaki

Arjuna, also radioprotectiveArjuna, also radioprotective Highest: Sangre de GradoHighest: Sangre de Grado


32

Sangre de GradoSangre de GradoCroton lechleriCroton lechleri

Highest antioxidant rating of 3100 foods, Highest antioxidant rating of 3100 foods, herbs, and supplements testedherbs, and supplements tested mmol/100 grams = 2897.11 mmol/100 grams = 2897.11

4x higher than triphala4x higher than triphala

90% proanthocyanidins 90% proanthocyanidins Grows in the Rain ForestGrows in the Rain Forest

PeruPeru Main use is for bleeding and wound healingMain use is for bleeding and wound healing

Causes erythrocyte aggregationCauses erythrocyte aggregation


33

Antioxidant Foods, Herbs, & Antioxidant Foods, Herbs, & Spices Spices

Cloves and CinnamonCloves and Cinnamon Fruits & VegetablesFruits & Vegetables

Especially those that are dark in colorEspecially those that are dark in color Acai and goji berriesAcai and goji berries Artichokes and beetsArtichokes and beets

Dark ChocolateDark Chocolate


34

Myricetin AntioxidantMyricetin Antioxidant

Flavonoid found in berries and grapesFlavonoid found in berries and grapes WalnutsWalnuts OnionsOnions Bayberry barkBayberry bark Red wineRed wine Green teaGreen tea


35

DNADNA

If the free radicalIf the free radical

reaction involvesreaction involves

strands of the strands of the DNA,DNA,

Serious Serious consequencesconsequences

can result.can result.


36

Ayurvedic Herbs for DNA Ayurvedic Herbs for DNA ProtectionProtection

Ashwagandha, Ashwagandha, Withania somniferaWithania somnifera AntioxidantAntioxidant Supports normal cortisol levelsSupports normal cortisol levels Protects against lipid peroxidationProtects against lipid peroxidation

Bacopa, Bacopa, Bacopa Bacopa monnieri Promotes healthy functioning of Promotes healthy functioning of

neurotransmittersneurotransmitters Tulsi, Tulsi, Ocimum tenuiflorumOcimum tenuiflorum

Helps regulate blood sugar and cholesterolHelps regulate blood sugar and cholesterol


37

Herbs that Repair DNAHerbs that Repair DNA

Sage (essential oil), Sage (essential oil), Salvia officinalisSalvia officinalis Anti-microbial, antifungal, antioxidant Anti-microbial, antifungal, antioxidant

Cat’s Claw, Cat’s Claw, Uncaria tomentosaUncaria tomentosa Improves functioning of DNA & RNAImproves functioning of DNA & RNA


38

NeurogenesisNeurogenesis

Astragalus, Astragalus, AstragalusAstragalus membranaceusmembranaceus Extend life of telomeresExtend life of telomeres Improve how immune cells respond to virusesImprove how immune cells respond to viruses

Cat’s Claw, Cat’s Claw, Uncaria tomentosaUncaria tomentosa Chromosome repairChromosome repair

Ashwagandha, Ashwagandha, Withania somniferaWithania somnifera Helps regenerate damaged neurons in the brainHelps regenerate damaged neurons in the brain

Brain traumaBrain trauma Infection by parasites or spirochetesInfection by parasites or spirochetes


39

Rasayanas and DhatusRasayanas and Dhatus

All rasayanas are antioxidantsAll rasayanas are antioxidants Promote resistance to diseasePromote resistance to disease Promote homeostasisPromote homeostasis Promote healthPromote health Promote optimal functioningPromote optimal functioning

All rasayanas promote longevityAll rasayanas promote longevity


40

The DhatusThe Dhatus

All nutrients are first assimilated by rasa All nutrients are first assimilated by rasa dhatu and refined for use by rakta dhatu dhatu and refined for use by rakta dhatu and the other dhatus.and the other dhatus.

There is assimilation and waste at each There is assimilation and waste at each stage of tissue renewal.stage of tissue renewal.

Only what is used as a nutrient forms the Only what is used as a nutrient forms the dhatu.dhatu.


41

Rasa DhatuRasa Dhatu

PlasmaPlasma Rasa dhatu is the sea in which blood Rasa dhatu is the sea in which blood

cells find nourishment.cells find nourishment. The quality of the fluid, safety of the The quality of the fluid, safety of the

fluid, and availability of high quality fluid, and availability of high quality nutrients determines the capacity to nutrients determines the capacity to sustain, regenerate, and rejuvenate all sustain, regenerate, and rejuvenate all other tissues of the body.other tissues of the body.


42

Taste of Rasa DhatuTaste of Rasa Dhatu

Sweet Sweet NutritiousNutritious

SaltySalty MineralsMinerals

Pungent, Sour, Bitter, & Astringent in Pungent, Sour, Bitter, & Astringent in lesser amountslesser amounts

The nutrients needed are best supplied by The nutrients needed are best supplied by juicejuice


43

Herbs for Rasa DhatuHerbs for Rasa Dhatu

Guduchi, Guduchi, Tinospora cordifoliaTinospora cordifolia Haritaki, Haritaki, Terminalia chebulaTerminalia chebula Shatavari, Shatavari, Asparagus racemosusAsparagus racemosus Jivanti, Jivanti, Leptadenia reticulataLeptadenia reticulata Punarnava, Punarnava, Boerhavia diffusaBoerhavia diffusa Bamboo manna Bamboo manna ShilajitShilajit


44

Western Herbs for Rasa Western Herbs for Rasa DhatuDhatu

FluidsFluids WaterWater Herbal infusionsHerbal infusions Juices from fruits or vegetables, especially okraJuices from fruits or vegetables, especially okra

Herbs that are mucilaginous and demulcentHerbs that are mucilaginous and demulcent Herbs that are pH balancingHerbs that are pH balancing Herbs that are rich in trace minerals Herbs that are rich in trace minerals

Nettles (Nettles (Urtica dioicaUrtica dioica), sea vegetables, licorice ), sea vegetables, licorice ((Glycyrrhiza glabra), Glycyrrhiza glabra), burdock (burdock (Arctium lappaArctium lappa))

Herbs that aid digestionHerbs that aid digestion Lemon Balm (Lemon Balm (Melissa officinalisMelissa officinalis))


45

BibliographyBibliography

Balch, James F., Balch, James F., The Super AntioxidantsThe Super Antioxidants, M. Evans & Company, Inc., , M. Evans & Company, Inc., New York, New York,

1998.1998.

Cox, Robert E., Cox, Robert E., The Elixir of ImmortalityThe Elixir of Immortality, Inner Traditions, Rochester, VT, , Inner Traditions, Rochester, VT, 2003.2003.

Halliwell, Barry & Gutteridge, John M.C., Halliwell, Barry & Gutteridge, John M.C., Free Radicals in Biology and Free Radicals in Biology and

MedicineMedicine, Fourth Edition, Oxford University Press, Oxford, 2010., Fourth Edition, Oxford University Press, Oxford, 2010.

Murthy, T. S. Ananta, Murthy, T. S. Ananta, TapaswijiTapaswiji, Sri Vishnu Ashram Trust Publication, , Sri Vishnu Ashram Trust Publication, Third Edition, Bangalore, 2003.Third Edition, Bangalore, 2003.

Schechter, Steven R., Schechter, Steven R., Fighting Radiation & Chemical Pollutants with Fighting Radiation & Chemical Pollutants with Foods, Herbs, & VitaminsFoods, Herbs, & Vitamins, Second Edition, Vitality Ink, Encinitas, CA., , Second Edition, Vitality Ink, Encinitas, CA., 1990.1990.

Winston, David & Maimes, Steven, Winston, David & Maimes, Steven, Adaptogens: Herbs for Strength, Adaptogens: Herbs for Strength, Stamina, and Stress ReliefStamina, and Stress Relief, Healing Arts Press, Rochster, VT, 2007., Healing Arts Press, Rochster, VT, 2007.


46

Bibliography AyurvedaBibliography Ayurveda

Dash, Bhagwan, Dash, Bhagwan, Alchemy and Metallic Medicines in AyurvedaAlchemy and Metallic Medicines in Ayurveda, , Concept Publishing Company, New Delhi, 1996, Reprinted 2003.Concept Publishing Company, New Delhi, 1996, Reprinted 2003.

Frawley, David, Frawley, David, Soma in Yoga and AyurvedaSoma in Yoga and Ayurveda, Lotus Press, Twin Lakes, , Lotus Press, Twin Lakes, WI, 2012.WI, 2012.

Ojha, J.K., Ojha, J.K., Chyawanprash: From Vedic to Genomic EraChyawanprash: From Vedic to Genomic Era, Chaukhamba , Chaukhamba Sanskrit Pratishthan, Delhi, 2003.Sanskrit Pratishthan, Delhi, 2003.

Sharma, B. D. & Acharya Bal Krishnan, Sharma, B. D. & Acharya Bal Krishnan, Vitality Strengthening Vitality Strengthening Astavarga PlantsAstavarga Plants, Divya Yog Mandir Trust, Haridwar, 2005 (?), Divya Yog Mandir Trust, Haridwar, 2005 (?)

Sharma, Hari, MD, Sharma, Hari, MD, Freedom from DiseaseFreedom from Disease, Veda Publishing, Toronto, , Veda Publishing, Toronto, 1993.1993.


47

Internet SourcesInternet Sources

Benzie, I.F.F. and Wachtel-Galor, S., editors, Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition, Boca Raton (FL): CRC Press, 2011.http://www.ncbi.nlm.nih.gov/books/NBK92763/

Carlsen, Monica H. et al, 2010

http://www.nutritionj.com/content/supplementary/1475-2891-9-3-s1.pdf


free radicals in the context of ayurvedic rejuvenative therapies presented by ingrid naiman for...

Documents

ingrid naiman

oxygen molecule

radiation damage copyright

free radical formation

free radical theory

irony oxygen

death copyright

stress copyright