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© 2014 PerkinElmer HUMAN HEALTH • ENVIRONMENTAL HEALTH From Visual Data Exploration and Analysis to Scientific Conclusions Alexandra Vamvakidou, PhD September 15th, 2016

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Page 1: From Visual Data Exploration and Analysis to Scientific ... · Imagine stories Scientists: Identify outliers See patterns and trends Create new hypotheses ... Trellis to display data

© 2014 PerkinElmer

HUMAN HEALTH • ENVIRONMENTAL HEALTH

From Visual Data Exploration and Analysis to

Scientific Conclusions

Alexandra Vamvakidou, PhD

September 15th, 2016

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The Power of a Visual Data

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We Collect Data to Compare and Add Knowledge

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Data is Everywhere

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Not looking at this kind of Data

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Visuals Help us with Data Exploration

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As Humans we Can…

Recognize people and objects

Navigate through obstacles

Understand mood in the scene

Imagine stories

Scientists:

Identify outliers

See patterns and trends

Create new hypotheses

“One picture is worth

a thousand words”

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Data Exploration

Traditional data analysis is very static

Takes time and requires highly focused questions

Obvious disadvantage

We miss out on important trends that we weren’t looking for

Unable to interpret the data to it’s full extent

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What if…

…data exploration was dynamic?

… getting answers to new questions was instantaneous?

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?

Ask a

question

Decide what you

will need

Execute the

Experiment

Look at Results

?

Run report

with changes

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Science Data is Deep Data

Lead Discovery High Throughout

Screening HCS/Multivariate

Analysis OMICS Analysis

Lead Discovery

SciStream

OMICSOffice HC Profiler

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SCIENTIFIC DATA INVOLVES DATA MASHUP, COMBINING DATA FROM VARIOUS TYPES AND SOURCES. YOU CAN WORK WITH HCS DATA, CHEMISTRY WITH STRUCTURES, PLATE BASED ASSAY OR GENOMICS DATA.

Chemistry and Structures HCS, HTS Gene Expression

SAR Drug Dose Response

Translational Medicine

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HCS loop

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SCISTREAM IS A GENERIC DATA LOADER TO BATCH IMPORT FILES, AGGREGATE AND ARRANGE RAW INSTRUMENT DATA AND METADATA IN SPOTFIRE.

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Scistream in the middle

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LEAD DISCOVERY IS AN ADD-ON FOR ANALYSIS OF CHEMISTRY DATA. IT ENABLES THE IMPORT, RENDERING, FILTERING AND ANALYSIS OF DATA WITH CHEMICAL STRUCTURES.

Visualizations + Chemical Intelligence

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OMICSOFFICE IS AN ADD-ON FOR THE ANALYSIS OF GENOMICS DATA USING GUIDED WORKFLOWS AS WELL AS A RICH TOOLKIT THAT INCLUDES ADVANCED STATISTICS, DATA INTEGRATION TOOLS AND FUNCTIONAL ANALYSIS METHODS.

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EXTENSIBILITY TO STATISTICAL ENGINES. THIS ALLOWS STATISTICIANS AND PROGRAMMERS TO BUILD ANALYTIC WORKFLOWS MORE QUICKLY AND ENABLE OTHERS TO USE THEM.

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Video

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Selecting the Right Chart Type for Your Data

Comparison

Data

Transition

Data

Composition

Data

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Labels and Tool Tips

Mark and display additional information

Hover over item to show different values

Display images, structures, links etc.

Trellis to display data with more granularity

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Filtering Schemes

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Creating a Self-Explanatory Drill-Down Interface

Details on Demand, Details Visualizations

Data selection depends on marked data in other visualization

Use trellis to provide title

Color settings are not reset anymore

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Summarizing and Annotating Charts: Text Areas

Extra information on the

analysis

Shortcuts to specific

selections and markings

To improve the overall

layout

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Collaborations

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Annotations

• Available in:

• Spotfire Business Author and

Spotfire Analyst,

• You can:

◦ Add textual descriptions to

visualizations in the form of a

text box appearing on top of a

visualization.

◦ Draw attention to the key points

in your visualization.

◦ Specify the color and width of

the text box,

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Using Multiple Data Tables

• Different data sources

◦ One-to-many relations between different data tables

◦ Visualizations generally use only 1 data table

• Same data in different pivot state

•Unpivot

•New column:

first(if([Drug]="Reference”,[Value],null))

OVER [Category]

Curve from Data Table

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In Summary

• Interactive

Visualizations

• R&D

Applications

• Access corporate and local data sources and spreadsheets

• Analyze and explore data with intuitive, interactive visualizations

• Capture and collaborate around analysis workflows

• Distribute analyses to colleagues

• Easy functional & biological analyses: Allowing researchers to

interpret biological relevance of their data

• Availability of specific guided workflows designed for different

genomic technologies with Click and Go® technology

• Powerful visualizations: Powered byTIBCO® Spotfire® platform,

OmicsOffice offers the best visualization and data mining options in

the market

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Thank you!

[email protected]

Join Us at the Interactive Stations to Learn More