fuliniual pathology - jcp.bmj.com · 113 medullarycarcinoma ofthethyroidwithcarcinoid-like features...

JANUARY 1993 VC

7.,~~~~~~~~~~~~~~~~~~~~~~~~~4.,

RfULINiuALPATHOLOGY

)L46NO 1

The Journal of the Association of Clinical Pathologists

1 John Lilleyman Editor 1986-1992 D Lowe

2 Guidelines for screening for Cryptosporidium in stools: Report ofa joint working groupD P Casemore, C Roberts

5 Out of Africa: Observations on the histopathology ofMycobacterium ulcerans infection J Hayan10 ACP Broadsheet 135: Isolation and identification methods for Escherichia coli and other Vero

cytotoxin producing strains H R Smith, SM Scotland

18 Cathepsin B expression in tumour cells and laminin distribution in pulmonary adenocarcinomaM Higashiyama, 0 Doi, K Kodama,H Yokouchi, R Tateishi

23 C-myc oncogene expression in anal squamous neoplasia 0 A Ogunbiyi, JH Scholefield,K Rogers,F Sharp, J H F Smith, S V Polacarz

28 Correlation between PCNA and AgNOR scores in non-Hodgkin's lymphomas using sequentialstaining technique F G Smith, P G Murray, J Crocker

32 Collagen remodelling in myocardia of patients with diabetesM Shimizu, K Umeda,N Sugihara, et al37 Intramural platelet deposition in cerebral vasculopathy ofsystemic lupus erythematosus D Ellison,

K Gatter, A Heryet,M Esiri41 Effects of azathioprine on response of renal anaemia to subcutaneous recombinant human

erythropoietin J E Howarth, HM Waters, D Shanks, et al45 High incidence of type II autoantibodies in pernicious anaemia HM Waters, D W Dawson,

J E Howarth, C G Geary48 Use of proliferation cell nuclear antigen immunoreactivity for distinguishing hydropic abortions

from partial hydatidiform moles U R Suresh, R J Hale, H Fox, CH Buckley51 Histopathological findings in oesophageal carcinoma with and without preoperative chemotherapy

S J Darnton, SM Allen, C W Edwards, HR Matthews56 Inverted hyperplastic polyposis of the colonN A Shepherd61 What is marrow fibrosis after treatment ofneuroblastoma? G E Turner,MM Reid64 Effect of the choice ofWHO International Reference Preparation for thromboplastin on

International Normalised Ratios L Poller, D A Taberner, JM Thomson, J Morris, R S Mibashan,N K Shinton

67 Audit of start of anticoagulation treatment in inpatients G Tan,H Cohen, F Taylor, J Gabbay72 Foreign body giant cell reactions and ossification associated with benign melanocytic naevi

WF Knox, L J McWilliam, E W Benbow, R F T McMahon,N Wilkinson, R Bonshek75 Ammonium metabolism and protection from urease mediated destruction in Helicobacter pylori

infection WD Neithercut, C Williams, M S Hossack, K E L McColl79 Evaluation ofnew streptococcal latex grouping kit A F Vicca, R E Stansfield, R G Masterton81 Instructions to Authors

83 Electron microscopic and immunohistochemical findings in a case ofolfactory'neuroblastomaZM Du, Y S Li, B F Wang

86 Mast cell numbers in melanocytic naevi and cutaneous neurofibromasN J Carr, A Y Warren88 Xanthogranulomatous gastritis: Association with xanthogranulomatous cholecystitis AI Guarino,

D Reale, G Micoli, P Tricomi, E Cristofori91 Florid vascular proliferation in repeated intussusception mimicking primary angiomatous lesion

K L Ramsden, J Newman, A Moran93 Origin of non-dialysable urinary glucoconjugates 00 Adedeji

95 Book Reviews * Notices

BMJ PUBLISHING GROUP

eders

per

ort reports

on 8 March 2019 by guest. P

rotected by copyright.http://jcp.bm

j.com/

J Clin P

athol: first published as on 1 January 1993. Dow

nloaded from

http://jcp.bmj.com/

VOLUME 46 * CONTENTS

No 1 JANUARY 1993 Page1 John Lilleyman, Editor 1986-1992 D Lowe

Leaders2 Guidelines for screening for Cryptosporidium in stools: Report of a joint working group D P Casemore, C Roberts5 Out of Africa: Observations on the histopathology of Mycobacterium ulcerans infection J Hayman

10 ACP Broadsheet 135: Isolation and identification methods for Escherichia coli and other Vero cytotoxin producingstrains H R Smith, S M Scotland

Papers18 Cathesin B expression in tumour cells and laminin distribution in pulmonary adenocarcinoma M Higashiyama,

0 Doi, K Kodama, H Yokouchi, R Tateishi23 C-myc oncogene expression in anal squamous neoplasia 0 A Ogunbiyi, J H Scholefield, K Rogers, F Sharp,

J H F Smith, S V Polacarz28 Correlation between PCNA and AgNOR scores in non-Hodgkin's lymphomas using sequential staining technique

F G Smith, P G Murray, Jf Crocker32 Collagen remodelling in myocardia of patients with diabetes M Shimizu, K Umeda, N Sugihara, et al37 Intramural platelet deposition in cerebral vasculopathy of systemic lupus erythematosus D Ellison, K Gatter,

A Heryet, M Esiri41 Effects of azathioprine on response of renal anaemia to subcutaneous recombinant human erythropoietin

Jf E Howarth, HM Waters, D Shanks, et al45 High incidence of type II autoantibodies in pernicious anaemia HM Waters, D W Dawson, _J E Howarth,

C G Geary48 Use of proliferation cell nuclear antigen immunoreactivity for distinguishing hydropic abortions from partial

hydatidiform moles U R Suresh, R J Hale, H Fox, C H Buckley51 Histopathological findings in oesophageal carcinoma with and without preoperative chemotherapy SJ Darnton,

SM Allen, 0 W Edwards, H R Matthews56 Inverted hyperplastic polyposis of the colon NA Shepherd61 What is marrow fibrosis after treatment of neuroblastoma? G E Turner, MM Reid64 Effect of the choice ofWHO International Reference Preparation for thromboplastin on International Normalised

Ratios L Poller, D A Taberner, J7M Thomson, J Morris, R S Mibashan, NK Shinton67 Audit of start of anticoagulation treatment in inpatients G Tan, H Cohen, F Taylor, J Gabbay72 Foreign body giant cell reactions and ossification associated with benign melanocytic naevi WF Knox,

L Jf Mc William, E W Benbow, R F T McMahon, N Wilkinson, R Bonshek75 Ammonium metabolism and protection from urease mediated destruction in Helicobacter pylori infection

WD Neithercut, C Williams, M S Hossack, KE L McColl79 Evaluation of new streptococcal latex grouping kit A F Vicca, R E Stansfield, R G Masterton81 Instructions to Authors

Short reports83 Electron microscopic and immunohistochemical findings in a case of olfactory neuroblastoma ZM Du, Y S Li,

B F Wang86 Mast cell numbers in melanocytic naevi and cutaneous neurofibromas NJr Carr, A Y Warren88 Xanthogranulomatous gastritis: Association with xanthogranulomatous cholecystitis M Guarino, D Reale, G Micoli,

P Ticomi, E Cristofori91 Florid vascular proliferation in repeated intussusception mimicking primary angiomatous lesion K L Ramsden,

J Newman, A Moran93 Origin of non-dialysable urinary glucoconjugates 0 0 Adedeji

Miscellanea95 Book Reviews * Notices

No 2 FEBRUARY 1993 Page Leaders97 The British Society for Haematology Guidelines on the use and monitoring of heparin 1992: Second revision

B T Colvin, T W Barrowcliffe on behalf ofBCSH Haemostasis and Thrombosis Task Force104 ACP Broadsheet 136: Detection and importance of anticardiolipin antibodies MA Khamashta, G R V Hughes

Papers108 Immunohistochemical characterisation of the costochrondral junction in SIDS R W Byard, B K Foster, S Byers113 Medullary carcinoma of the thyroid with carcinoid-like features H R Harach, U Bergholm118 Importance of apoptosis in the histopathology of drug related lesions in the large intestine F D Lee123 Monotypic plasma cells in labial salivary glands of patients with Sjogren's syndrome: Prognosticator for systemic

lymphoproliferative disease C Bodeutsch, P GM de Wilde, L Kater, et al129 Combined proliferating cell nuclear antigen and morphometric analysis in the diagnosis of cutaneous lymphoid

infiltrates A M T Clarke, WA Reid, A SI ack135 Comparison of flow and static image cutometry in the determination of ploidy D Lanigan, PA McLean, B Curran,

M Leader140 Quantitative and qualitative comparison ofDNA amplification by PCR with immunofluorescence staining for

diagnosis of Pneumocystis carinii pneumonia TR Leigh, B G Gazzard, A Rowbottom, Jf V Collins145 New phenotypic typing scheme for group B streptococci S R Heard, J A Mawn149 Prognostic value of epidermal growth factor receptor expression in cervical carcinoma R Jt Hale, C H Buckley,

WJ7 Gullick, H Fox, J Williams, F L Wilcox



j.com/

J Clin P


nloaded from

http://jcp.bmj.com/

154 Adenovirus and intranuclear inclusions in appendices in intussusception HJ Porter, CJ H Padfield, L C Peres,L Hirschowitz, PJ Berry

159 Proliferative activity of urothelial neoplasms: Comparison of BrdU incorporation, Ki67 expression, and nucleolarorganiser regions C Limas, A Bigler, R Bair, P Bernhart, P Reddy

Short reports166 Epidermal growth factor receptor determination on tumour imprints D _r Hastrich, JM Dunn, P Newcomb, et al169 p53 expression in dyskeratosis congenita: a marker for oral premalignancy? G R Ogden, D P Lane, D M Chisholm171 Demonstration ofmRNA using digoxigenin labelled oligonucleotide probes for in situ hybridisation in formamide

free conditions G A Thomas, H G Davies, E D Williams175 Intraduct papilloma of parotid gland PH King, J Hill177 Lymph node disease with lymphocytic abnormal chromatin clumping in a myelodysplastic/myeloprolioferative

syndrome J Gardais180 Neutropenic enterocolitis associated with Clostridium tertium N Coleman, G Spiers, Jf Khan, V Broadbent,

D G D Wight, R E Warren183 Mixed adenocarcinoma/carotid tumour of large bowel in a patient with Crohn's disease Y L Hock, K WM Scott,

R H Grace185 Epithelial myoepithelial tumour of the tracheal gland H Horinouchi, T Ishihara, M Kawamura, et al

Miscellanea188 Correspondence - Corrections * Notices

No 3 MARCH 1993 Page Leaders193 How to tackle a possible Creutzfeldt-Jakob disease necropsy J E Bell, J W Ironside198 ICSH recommendations for measurement of erythrocyte sedimentation rate ICSH Expert Panel

Papers204 Expression of c-myc and c-fins oncogenes in trophoblastic cells in hydatidiform mole and normal human placenta

A N Y Cheung, G Srivastava, S Pittaluga, TK Man, H Ngan, R Jf Collins208 Observer reliability in assessing villitis of unknown aetiology T YKihong, A Staples, L Moore, R WByard211 Expression of c-myc and bel-2 oncogene products in Reed-Steinberg cells independent of presence of Epstein-Barr

virus NM Jiwa, P Kanavaros, P Van Der Valk, et al218 Tenascin immunoreactivity in normal and pathological bone marrow Y Soini, D Kamel, M Apaja-Sarkkinen,

I Virtanen, V-P Lehto222 Pulmonary platelet aggregates: Possible cause of sudden peroperative death in adults undergoing liver

transplantation EA Sankey, Jf Crow, S V Mallett, et al228 Radiation disease of the urinary tract: Histological fetures of 18 cases UR Suresh, VJ Smith, E W Lupton,

N YHaboubi232 Certifying the cause of death: an audit of wording inaccuracies D N Slater235 Bile reflux and intestinal metaplasia in gastric mucosa GM Sobala, HJ O'Connor, E P Dewar, R F G King,

A T R Axon, MF Dixon241 Mucin exocytosis: a major target for Helicobacter pylori I Micots, C Augeron, C L Laboisse, F Muzeau, F Migraud246 Tissue distribution of autoantigen specific for primary sclerosing cholangitis SK Lo, R W Chapman, KA Fleming250 Ethanol challenge in non-alcoholic patients with schistosomiasis R D Martins, D R Borges254 Assay of gastricsin and individual pepsins in human gastric juice A TJones, KK Balan, SA Jenkins, R Sutton,

M Critchley, NB Roberts259 Comparison between liver and serum concentrations ofmannan binding proteinN G Ryley, A R Heryet, Jf Lu,

KBM Reid, KA Fleming264 Is serum creatine kinase:aspartate aminotransferase ratio useful for diagnosing acute myocardial infarction in elderly

patients? D G Swain, RM Gama, P G Nightingale267 Lipoprotein (a) as an independent risk factor for myocardial infarction in patients with common

hypercholesterolaemia G F Watts, EM Kearney, NA Taub, B M Slavin

Short reports271 Fatal pulmonary infection due to Mycobacterium fortuitum M PA Lessing,MM Walker273 Human T lymphotropic virus type I associated myelopathy with pulmonary and cutaneous lesions H Kuwabara,

Jf Katanaka, M Nagai, et al276 Simple technique for detecting RNA viruses by PCR in single sections of wax embedded tissue C Jf Woodall,

NJ Watt, G B Clements278 Needle tract implantation of thymoma after transthoracic needle biopsy T Nagasaka, N Nakashima, H Nunome280 Biochemical diagnosis of phaeochromocytoma: Two instructive case reportsMF Stewart, P Reed, C Weinkove,

KJ Moriarty, A Jf Ralston283 Deternination of serum cholesterol concentration in the presence of ascorbate PJ Lumb, B M Slavin

Miscellanea235 Correspondence * Book Reviews * Notices

No 4 APRIL 1993 Page Leaders289 The white cell differential: Personal obsenrvtions D M Reardon, B Warner292 ACP Broadsheet 137: Obtaining samples at post mortem examination for toxicological and biochemical analyses

A R WForrest

Papers297 Clonality of chronic neutrophilic leukaemia associated with myeloma: Analysis using the X-linked probe M27fl

G R Standen, FJ Steers, L Jones299 Prospective comparative study of computer programs used for management of warfarin L Poller, D Wright,

M Rowlands



j.com/

J Clin P


nloaded from

http://jcp.bmj.com/

304 Geographical variation in prevalence of hepatitis B virus DNA in HBsAg negative patients Y-M D Lo, E S-F Lo,WZMehal, etal

309 Evaluation of non-radioactive trivalent DNA probe (LT, STIa, STlb) for detecting enterotoxigenic Escherichia coliPA Chapman, CM Daly

313 Detection of Chlamydia pneumoniae and Chlamydia psittaci in sputum samples by PCR C Y W Tong, M Sillis318 Use ofPCR in routine diagnosis of treated and untreated pulmonary tuberculosis K Y Yuen, KS Chan,

CM Chan, et al323 Distribution of 0-acetylated sialomucin in the normal and diseased gastrointestinal tract shown by a new

monoclonal antibody _J D Milton, D Ecdeston, N Parker, et al330 Overexpression ofp53 protein in Barrett's syndrome with malignant transformation J-F FLjou, F Potet, F Muzeau,

F Le Pelletier, F Fekiet, D Henin334 CD68 reactivity of non-macrophage derived tumours in cytological specimens IA Doussis, K C Gatter, D YMason337 Analysis of antigen receptor genes in Hodgkin's disease C A Angel, JH Pningle, J Naylor, KP West, I Lauder341 Cytokine gene expression in skin and lymphoid organs in graft versus host disease A WRowbottom, J Norton,

P G Riches, J R Hobbs, R L Powles, J P Sloane346 Diagnosis of complete molar pregnancy by microsatellites in archival material S A Lane, G R Taylor, B Ozols,

P Quirke349 Oestrogen and progesterone receptor expression in mammary fibromatosis S A Rasbridge, C E Gillett, R R Millis352 Keratin profiles of normal and malignant oral mucosa using exfoliative cytology G R Ogden, S McQueen,

DM Chisholm, E B Lane357 Response analysis in histopathology external quality assessment schemes PN Furness, I Lauder364 Intensity of inflammatory damage and serum lipid peroxide concentrations in liver disease C Fabris, M Pirisi,

M P Panozzo, et al

Short reports368 Effect of f, propiolactone on specific antibody measurements by ELISA A E Agbarakwe, SA Misbah, H Griffiths,

HM Chapel370 Foamy changes of placental cells in probable f, glucuronidase deficiency associated with hydrops fetalis J Nelson,

B Kenny, D O'Hard, A Harper, D Broadhead372 Antibacterial action of the urease inhibitor acetohydroxamic acid on Helicobacter pylon K Phillips, D J Munster,

R A Allardyce, PF Bagshaw374 Latex agglutination test for identification of Pseudomonas pseudomalkeM D Smith, V Wuthiekanun, A L Walsh,

TL Pitt376 Lymphocytic mastopathy associated with infiltrating lobular breast carcinoma R Chetty, A E Butler378 PCR amplification ofDNA from stained cytological smears K Gall, D PavidY Pavelid S Audy-Jurkovic K Pavelic

Miscellanea380 Correspondence * Book Reviews * Notices

No 5 MAY 1993 Page Leaders385 Ethical issues and clinical pathology D N Barron388 ACP Broadsheet 138: Gross examination of uterine specimens Jf Scurry, K Patel, M Wells

Papers394 Effects of culture media on detection of methicillin resistance in Staphylococcus aureus and coagulase negative

staphylococci by disc diffusion methods LM Milne, MR Crow, A GM Emptage, J B Selkon398 Bacteraemia due to recurrent reinfection with Staphylococcus epidermidis associated with defective opsonisation and

procidin function in serum L R I Baker, A L Brown, J R Stephenson, et al403 Comparison of techniques for antimicrobial susceptibility testing of mycobacteria D I Limb, P F Wheat,

R C Spencer, G S Hams, A B Rayner, B Watt408 Evaluation of sensitivity of 10 diagnostic assays for Chlamydia trachomatis by use of a simple laboratory procedure

B J Thomas, EJ Macleod, D Taylor-Robinson411 Serological differentiation between acute (late control) and endocarditis Q fever F Soriano, M T Camacho, C Ponte,

P G6mez415 Cytomegalovirus pneumonitis and bone marrow transplantation: Identification of a specific high risk group

A BM Foot, EQ Caul, A P Roome, JM Darvike, A Oakhill420 Coeliac disease with histological features of peptic duodenitis: Value of assessment of intraepithelial lymphocytes

M DJ7effers, D O'B Hourihane425 Abnormal growth factor and cytokine expression in Dupuytren's contracture KS Baird, JfF Crossan, S H Ralston429 Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal

cell carcinomas of the skin R Poulsom, A M Hanby, M PignateUi, et al437 Use of Probemix and OmniProbe biotinylated cDNA probes for detecting HPV infection in biopsy specimens from

the genital tract I Zehbe, E Rylander, A Strand, E Wilander441 Vimentin expression in benign and malignant breast epitheliumM Heatley, C Whiteside, P Maxwell, P Toner446 Proliferating cell nuclear antigen (PCNA) and nucleolar organiser regions in Hodgkin's disease: Correlation with

morphologyJ Freeman, D B Kellock, C C-W Yu, J Crocker, D A Levison, PA Hall450 Villous adenoma of the bladder J L Channer, J L Williams, L Henry453 Use ofplasma iodine assay for diagnosing thyroid disorders PAllain, S Berre, N Krari, et al456 Bromine and thyroid hormone activity PAllain, S Berre, N Krari, et al459 Use of multichannel discrete analyser to reduce unnecessary biochemical tests A Tarpey, WD Neithercut462 Measurement of urea and ammonium concentrations in gastric juice WD Neithercut, A M El Nujumi,

KE L McColl465 l,2-Glycoprotein-1 (apolipoprotein H) excretion and renal tubular malfinction in diabetic patients without clinical

proteinuria M Lapsley, F VFlynn, PA Sansom470 Analysis of von Willebrand factor multimers using a commercially available enhanced chemiluminescence kit

A M Cumming, R T Wensley



j.com/

J Clin P


nloaded from

http://jcp.bmj.com/

Short reports474 Colonial variation in vancomycin resistant Enterococcus faecium L WJ Baillie, JJ Wade, M W Casewell475 Measurement of serum arabinitol by gas-liquid chomatography: Limitations for detection of systemic candida

infections C McSharry, C Lewis, G Cruickshank, MD Richardson477 Yersinia enterocolitica septicaemia from transfusion of red cell concentrate stored for 16 days B L Jones, MH Saw,

M F Hanson, M J Mackie, J Scott, WG Murphy479 Comparison of the use of antibodies to a smooth muscle actin and desmin in pulmonary lymphangioleiomyomatosis

TJ Matthews, D Hornal, MN Sheppard481 Erdheim-Chester disease with epiphyseal and systemic disease NA Athanasou, C Barbatis483 Fatal non-malignant ulceration in the gastric tube after oesophagectomyM McDermott, D O'B Hourihane

Miscellanea486 Book Reviews * Notices * Corrections

No 6 JUNE 1993 Page Leaders489 Guidelines on the prevention, investigation and management of thrombosis associated with pregnancy B T Colvin497 Neonatal screening R J Politt500 ACP Broadsheet 139: Post mortem techniques in the evaluation of neck injury P Vanezis

Papers507 Immunohistochemical analysis of p53 expression in anal squamous neoplasia 0 A Ogunbiyi, J H Scholefield,

J HF Smith, S V Polacarz, K Rogers, F Sharp513 Childhood B cell lymphomas arising in the mediastinum TF Carr, L Lockwood, R F Stevens, et al517 Complement and the recruitment of mononuclear osteoclasts D C Mangham, D J Scoones, M T Drayson522 Clinicopathological features of untreated fibrous hamartoma of infancy SE E Efem, MD Ekpo525 Poor prognostic value of proliferating cell nuclear antigen labelling index in breast carcinomaM Thomas,

M Noguchi, H Kitagawa, K Kinoshita, I Miyazaki529 Monocyte esterase deficiency in gastrointestinal cancer G M Markey, R C Curry, D Swain, et al533 Endemic acinetobacter in intensive care units: Epidemiology and clinical impact L Dijkshoorn, R van Dalen,

A van Ooyen, et al537 Correlations between holo-transcobalamin II, holo-haptocornin, and total B12 in serum samples from healthy

subjects and patients S N Wickramasinghe, S Fida540 Identification of Helicobacterpylori DNA in the mouths and stomachs of patients with gastritis using PCR

N PMapstone, D A F Lynch, FA Lewis, et al544 Effect of Helicobacterpylori infection on intragastric urea and ammonium concentrations in patients with chronic

renal failure WD Neithercut, PA Rowe, AM El Nujumi, S Dahill, KE L McCol548 Sequential reactivity of serum against cyst antigens in Toxoplasma infection G Woodison, A H Balfour, J E Smith551 Diagnosis ofhuman toxocariasis by antigen capture enzyme linked immunosorbent assay SH Gillespie, D Bidwell,

A Voller, B D Robertson, R M Maizels555 Comparison of techniques for detecting antigens of Giardia lamblia and Cryptosporidium parvum in faeces

G H Tee, A H Moody, A Hunt Cooke, P L Chiodini

Short reports559 Safer staining method for acid fast bacilli R C Ellis, LA Zabrowarny561 Effect of transport medium and transportation time on culture of Helicobacterpylori from gastric biopsy specimens

R A Veenendaal, A T Lichtendahl-Bernards, A S Penia, H Ph Endtz, C PA Van Boven, C B H W Lamers564 Use of fine needle aspiration cytology for investigating lymphadenopathy in HIV positive patients

E Martin-Bates, A Tanner, SK Suvarna, G Glazer, D V Coleman567 Speeding up necropsy histology reports in a teaching hospital E WBenbow, J C Howard569 Apocrine metaplasia: a new type of Miillerian metaplasia C Allen, S Johnson570 Primary splenic lymphoma with filiform ultrastructure UR Suresh, B P Eyden, S S Banerjee, N L Reeve573 Human papillomavirus in squamous cell carcinoma of the oesophagus associated with tylosisM TAshworth,

I WMcDicken, S A Southern, J R G Nash576 Collagenase digestion of bone marrow trephine biopsy specimens: an important adjunct to haematological diagnosis

when marrow aspiration fails Z TMaung, NP Bown, PJ Hamilton

Miscellanea578 Letters * Book Reviews * Notices

No 7 JULY 1993 Page Leaders585 New technology in hospital blood banking J KM Duguid, IM Bromilow589 ACP Broadsheet 140: Techniques in pulmonary cytopathologyJA Young596 Early clinical pathologists: Robert Koch (1843-1910) S R Lakhani

Papers599 Can histopathologists reliably diagnose molar pregnancy? A J Howat, S Beck, H Fox, et al603 Histopathological changes in venous grafts and in varicose and non-varicose veins A K Charles, GA Gresham607 Immunoglobulin and complement deposition in glomeruli of 756 subjects who had committed suicide or met with

a violent death J Vans, I Rantala, A Pasternack, et al611 Stromal cell populations in necropsy bone marrow sections from allogeneic marrow recipients and non-transplant

patients SA Dilly, C JJJagger, J P Sloane617 Rapidly fatal necrotising fasciitis caused by Streptococcus pyogenes PM W Donaldson, B Naylor, J W Lowe,

D R Gouldesbrough621 K-ras point mutations in routinely processed tissues: Non-radioactive screening by single strand conformational

polymorphism analysis S H Korn, P TM Moerkerk, A F PM de Goeij



j.com/

J Clin P


nloaded from

http://jcp.bmj.com/

624 Sensitivity ofPCR in detecting monoclonal B cell proliferations F C Ling, C E Clarke, WE N Corbett,D P Lillicrap

628 Toxoplasma infection and systemic lupus erythematosus: Analysis of the serological response by immunoblottingI Noel, A H Balfour, M H Wilcox

633 Detection of the C protein gene among group B streptococci using PCR JA Mawn, A J Simpson, S R Heard637 Multipoint identification of Enterobacteriaceae: Report of the British Society for Microbial Technology collaborative

study T G Winstanley, D I Limb, PF Wheat, C D Nicol642 Phase contrast microscopic examination of urinary erythrocytes to localise source of bleeding: an overlooked

technique? KS Mohammad, A S Bdesha, ME Snell, R ON Witherow, D V Coleman646 Detection of reactivation and size variation in the regulatory region ofJC virus in brain tissue WZ Mehal,

MM Esiri, Y-M D Lo, R W Chapman, KA Fleming650 Vitreous humour and cerebrospinal fluid hypoxanthine concentration as a marker of pre-mortem hypoxia in SIDS

KH Carpenter, J R Bonham, E Worthy, S Variend654 Plasma intestinal alkaline phosphatase isoenzymes in neonates with bowel necrosis R McLachlan, J Coakley,

L Murton, N Campbell660 Pharmacokinetics of sex steroids in patients with fl thalassaemia majorM Katz, Vde Sanctis, C Vullo, B Wonke,

HH G McGarrigle, B Bagni665 Lupus anticoagulant activity of some antiphospholipid antibodies against phospholipid bound fl2 glycoprotein I

D M Keeling, A J G Wilson, IJMackie, DA Isenberg, SJ Machin668 Immunophenotypic characterisation of acute leukaemia after polycythemia vera JM Hernaindez, A Orfao,

M Gonzdlez, et al

Short reports672 Eosinophilic leukaemia with trisomy 8 and double gammopathy I Ribeiro, I Rio Carvalho, M Fontes, et al674 Pericardial extramedullary haemopoiesis in chronic myelomonocytic leukaemia C R Bradford, S R Smith, J P Wallis676 p53 Expression in three separate tumours from a patient with Li-Fraumeni's syndrome P King, A W Craft,

A J Malcolm678 Waldenstrom's macroglobulinaemia secreting a paraprotein with lupus anticoagulant activity: Possible association

with gastrointestinal tract disease and malabsorption R C Tait, PK Oogarah, J B Houghton, S E Farrand,M R Haeney

680 Terminal subculture of blood cultures using a multipoint inoculator device KJr Thickett, DJ W Dabbs, R C Spencer682 Expression of parathyroid hormone related peptide in human pituitary tumoursM Ito, H Enomoto, T Usa, et al684 Histology compared with chemical testing for urease for rapid detection of Helicobacter pylori in gastric biopsy

specimens A M Zaitoun

Miscellanea686 Book Reviews - Notices - Correction

No 8 AUGUST 1993 Page Leaders689 Near patient testing: the challenge for clinical pathology D J Goldie, H Kemp691 Biliary tract pathology in patients with AIDS R D Goldin, J Hunt

Papers694 Diagnosis of intestinal and disseminated microsporidial infections in patients with HIV by a new rapid fluorescence

technique T van Gool, F Snijders, P Reiss, et al700 Negative cytology preceding cervical cancer: Causes and preventionJ H Robertson, B Woodend703 Immunohistochemical study of tissue factor expression in normal intestine and idiopathic inflammatory bowel

disease L More, R Sim, M Hudson, A P Dhillon, R Pounder, A J Wakefield709 Strawberry gums: a clinicopathological manifestation diagnostic of Wegener's granulomatosis? S S Napier,

_'A Allen, C R Invuin, D R McCluskey713 Changes in numbers of epidermal cell adhesion molecules caused by oral cyclosporin in psoriasis B D Edwards,

SM Andrew, J B O'Driscoll, R J G Chalmers, F WBallardie, A J Freemont718 Human papillomavirus DNA in glandular lesions of the uterine cervixH Samaratunga, N Cox, R G Wright722 Biochemical and muscle studies in patients with acute onset post viral fatigue syndrome VR Preedy, D G Smith,

J R Salisbury, TJI Peters727 Is high AgNOR quantity in hepatocytes associated with increased risk of hepatocellular carcinoma in chronic liver

disease?M Derenzini, D Treri, F Oliveri, et al730 Familial hypercholesterolaemia: Pilot study to identify children at risk C J Taylor, S Olpin, J Rattenbury, et al734 Biochemical detection of phaeochromocytoma: Should we still be measuring urinary HMMA? R T Peaston, L C Lai738 Benign familial hyperphosphatasaemia as a cause of unexplained increase in plasma alkaline phosphatase activity

S B Rosalki, A Y Foo, J S Dooley742 Cryopreservation of red blood cells: Effect of freezing on red cell quality and residual lymphocyte immunogenicity

A Farrugia, N Shea, S Knowles, et al746 Bacteriological evaluation of a down-draught necropsy table ventilation system WAl-Wali, C C Kibbler,

J E McLaughlin750 Enhanced cultivation of Helicobacter pylori in liquid media HX Xia, L English, C T Keane, C A O'Morain754 Distribution of Helicobacter pylori colonisation and associated gastric inflammatory changes: Difference between

patients with duodenal and gastric ulcers J A Louw, V Falck, C van Rensburg, J Zak, G Adams, IN Marks757 Cytokines in stools of children with inflammatory bowel disease or infective diarrhoea S NichoUs, S Stephens,

C P Braegger, JA Walker-Smith, T TMacdonald761 Interaction of coagulase negative staphylococci with lectins J Wynne Jones

Short reports764 Acute myelomonocytic leukaemia following atypical congenital rubella S Jf Kelly, T Gibbs, C H Cheetham766 Combined silver Perls's stain for differential staining of ringed sideroblasts and marrow iron K T Tham, J7 B Cousar769 Aztreonam selective agar for Gram positive bacteria W Wood, G Harvey, E S Olson, TM S Reid



j.com/

J Clin P


nloaded from

http://jcp.bmj.com/

771 Pseudotumoral amyloidosis of fl,2-microglobulin origin in the buttock of a patient receiving long term haemodialysisJ7 Fernandez-Alonso, C Rios-Camacho, A Valenzuela-Castanio, J L Rocha-CastiUa

773 Diagnosis of childhood BK virus cystitis by electron microscopy and PCRK Saitoh, N Sugae, N Koike, YAkiyama,Y Iwamura, H Kimura

776 Frozen section simulation of trabecular adenoma and medullary cancer by papillary thyroid carcinoma A C Andrew,J M S WiUliamson

778 Rearrangements of c-myc and c-abl genes in tumour cells in Burkitt's lymphoma S Casares, JM Rodriguez,A Martin, A Parrado

Miscellanea780 Correspondence * Book Reviews - Notices

No 9 SEPTEMBER 1993

No 10 OCTOBER 1993

Page Leaders785 Current thoughts on the pathogenesis of graft versus host disease A L Appleton, L Sviland790 ACP Broadsheet 141: Role of endocrine biochemistry laboratories in the investigation of infertility G H Beastall

Papers795 Computed cell cycle and DNA histogram analyses in image cytometry in breast cancer R Montironi, L Diamanti,

A Santineli, et al801 Immunoelectron microscopy of acute graft versus host disease of the skin after allogeneic bone marrow

transplantationM Takata, T Imai, T Hirone806 Wide needle aspiration cytology in the diagnosis of lymphadenopathy in Zambia PS Patil, C Bem810 Proliferative activity of normal and neoplastic urothelium and its relation to epidermal growth factor and transferrin

receptors C Limas, R Bair, P Bernhart, P Reddy817 Evaluation of Questor urine screening system for bacteriuria and pyuria M Stevens, CJ Mitchell, SA Livsey,

CA MacDonald822 Use of a commercial PCR kit for detecting Chlamydia trachomatis I WSmith, C L Morrison, C Patmizio, A McMillan826 Serum pepsinogen I and II concentrations and IgG antibody to Helicobacter pylori in dyspeptic patients G Biasco,

GM Paganelli, D Vaira, et al829 Selective medium for thermophilic campylobacters including Campylobacter upsaliensis S TAspinall, D RA Wareing,

P G Hayward, DN Hutchinson832 Prevalence of lymphoid follicles and aggregates in Helicobacter pylori gastritis in antral and body mucosa S Eidt,

M Stolte836 Prostaglandin E, in gastric mucosa of children with Helicobacter pylori gastritis: Relation to thickness of mucus gel

layer G Oderda, M D'Alessandro, PMariani, et al840 Use of recombinant human parvovirus B19 antigens in serological assays HA Cubie, E E Leslie, S Smith, et al846 Lymphocyte transformation responses to phytohaemagglutinin and Pokeweed mitogen in patients at differing stages

ofHIV infection: Are they worth measuring? A S Bansal, A Moran, M Potter, R Taylor, MR Haeney, B KMandal849 Epstein-Barr virus in carcinoma of the vulva A N Y Cheung, U S Khoo, K YKwong, G Srivastava, RJr Collins852 Evaluation of high performance liquid chromatography for routine estimation of haemoglobins A2 and F G B Tan,

TCAw, RA Dunstan, SH Lee857 Use of plasma ferritin concentration to diagnose iron deficiency in elderly patients TL Holyoake, DJ Stott,

PJ McKay, A Hendry, J B MacDonald, NP Lucie861 Increased pentane and carbon disulfide in the breath of patients with schizophrenia M Phillips, M Sabas, J Greenberg

Short reports865 Fatal case of echovirus type 9 encephalitisMA Zuckerman, M Sheaff, J E Martin, CM Gabriel867 Benign cystic peritoneal mesothelioma D S Bhandarkar, VJ Smith, D A Evans, T V Taylor869 Multiple benign stromal cell tumours of the small bowel J A Gall, R Chetty, A J7 Kemp, J C B Penfold872 Mesenteric lipodystrophyM S Bashir, C R Abbott874 Multinucleated stromal giant cells of the colonic lamina propria in ulcerative colitisMA Pitt, WF Knox,

N YHaboubi876 Effect of embolisation of meningioma on Ki-67 proliferation index W Paulus, J Meixensberger, E Honfmann,

WRoggendorf878 Errors in automated reticulocyte counts due to Heinz bodies R F Hinchliffe

Miscellanea880 Book Review * Notices * Errata

Page Leaders881 Update on special techniques in routine cytopathology I D Buley886 Bodies associated with fires WLawler

Papers890 Cost of gentamicin assays carried out by microbiology laboratories PF Vacani, MMH Malek, P G Davey896 Mandatory use of confirmation stage with Chlamydiazyme during urinary sediment analysis J R Anderson,

G Mumtaz, P Mulhare, J Poddar, G L Ridgway898 Electron microscopic changes in Enterocytozoon bieneusi following treatment with albendazole C Blanshard,

D S Ellis, S P Dowell, G Tovey, B G Gazzard903 Immunological and ultrastructural studies in acute biphenotypic leukaemia VShetty, A Chitale, EMatutes,

V Buccheri, R Morilla, D Catovsky



j.com/

J Clin P


nloaded from

http://jcp.bmj.com/

908 Role of fl2 glycoprotein I and anti-phospholipid antibodies in activation of protein C in vitro DM Keeling,A J G Wilson, IJ Mackie, D A Isenberg, S Machin

912 Evaluation of sensitivity of 10 diagnostic assays for Chlamydia trachomatis by use of a simple laboratory procedureB Jf Thomas, EJf MacLeod, D Taylor-Robinson

915 Haemopoietic regrowth after chemotherapy for acute leukaemia: an immunohistochemical study of bone marrowtrephine biopsy specimens B S Wilkins, A G Bostanci, MF Ryan, D B Jones

922 Expression ofMUC2 epithelial mucin in breast carcinomaMD Walsh, MA McGuckin, P L Devine, B G Hohn,R G Wright

926 Distribution of ybT-cells in the bronchial tree of smokers and non-smokers I Richmond, G E Pritchard,TAshcroft, PA Corms, EH Walters

931 Epstein-Barr virus in normal, pre-malignant, and malignant lesions of the uterine cervix R J Landers, JJ O'Leary,M Crowley, et al

936 Detection ofhuman papillomavirus infection by non-isotopic in situ hybridisation in condylomatous and CINlesions R PoUalnen, S Vuopala, V-P Lehto

940 Detection of immunoglobulin heavy chain gene rearrangements in Hodgkin's disease using PCR CA Angel,J HPringle, L Primrose, I Lauder

943 Nucleolar organiser regions and survival in patients with non-Hodgkin's lymphomas classified by the workingformulation _Jakib-Razumovi4 D Tentor,M Petrovecki, I Radman

948 Prognostic importance ofDNA flow cytometric variables in rhabdomyosarcomas L C D Wijnaendts,J C van der Linden, PJ van Diest, et al

Short reports953 Necrotising granulomas of the uterine corpus A B Akosa, F Boret955 T cell lymphoid aggregates in bone marrow in idiopathic hypereosinophilic syndrome J Metz, KM McGrath,

HF Savoia, C G Begley, R Chetty959 Malakoplakia and adenocarcinoma of the caecum: a rare association D Sandmeier, L Guillou961 Mesenchymal chondrosarcoma arising in fibrous dysplasia of the femur J B BlackweUl963 Hypochromic macrocytes: are they reticulocytes? B J Bain, IA J Cavil965 Fatal infection associated with group C streptococci A C Bateman, A D Ramsay, A P PaUett968 Acute herpes hepatitis in pregnancy C G Fink, S Jf Read, J Hopkin, T Peto, S Gould, J B Kurtz

Miscellanea972 Correspondence - Book Reviews * Notices * Corrections

No 11 NOVEMBER Page Leaders977 Molecular genetics of disorders ofhaem biosynthesis G H Elder982 ACP Broadsheet 142: Measurement of carbon monoxide and cyanide in blood R WMayes

Papers989 Use of histopathology services by general practitioners: Recent changes in referral practice K Shorrock993 Immunohistochemistry of neurone specific enolase with y subunit specific anti-peptide monoclonal antibodies

G J Murray, M E Duncan, W T Melvin, I E Fothergill997 Gastric cancer and Helicobacterpylri infectionK S Clarkson, KP West1000 Use of histomorphometry in the assessment of fatal vertebral artery dissection C PJohnson, W Lawler, J Burns1004 Coexpression of intercellular adhesion molecule-I and class I major histocompatibility complex antigens on

hepatocyte membrane in chronic viral hepatitis CM Chu, YF Liaw1009 Epidermal growth factor receptor immunohistochemistry in different histological types of infiltrating breast

carcinomaM Martinazzi, F Crivelli, C Zampati, S Martinazzi1011 Histochemistry of mucin secreting components in mucoepidermoid and adenosquamous carcinoma of the

oesophagus K Y Lam, S L Loke, L TMa1016 Effect of tumour-associated tissue eosinophilia on survival ofwomen with stage IB carcinoma of the uterine cervix

PB Bethwaite, LU Holloway, M-L Yeong, A Thornton1021 PCR analysis of the upstream regulatory region of human papillomavirus genomes in cervical intraepithelial

neoplasia and cervical carcinoma YK Donaldson, MJ Arends, E Duvall, C C Bird1024 Malignant transformation of osteoblastoma: Study using image analysis microdensitometry J Grace, S McCarthy,

R Stankovic, WMarsden1030 Sea blue histiocytosis: a common abnormality of the bone marrow in myelodysplastic syndromesM R Howard,

PJ L Kesteven1033 Skeletal mastocytosis SM Andrew, A J Freemont1036 Iron overload in multiply transfused patients who are HIV seropositive R Goldin, M Wilkins, S Dourakis, J Parkin,

R Lindley1039 Cerebrospinal fluid concentration of fibronectin in patients with HIV-1 infection and central nervous system

disorders D Torre, C Zeroli, G Ferrario, G Bonetta, G P Fiori, R Martegani1042 Quantitation of vitronectin in serum: Evaluation of its usefulness in routine clinical practice NA M Boyd,

A R Bradwell, RA Thompson1046 Development of an internal quality assessment scheme in a clinical bacteriology laboratory C E Constantine,

M Amphlett, M Farrington, et al

Short reports1051 How many microbiology consultants are needed? G E Bignardi1053 Patients with haemolytic uraemic syndrome caused by Escherichia coli 0157: Absence of antibodies to Vero cytotoxin

1 (VT1) or VT2 H Chart, D Law, B Rowe, D WKAcheson1055 Plasma coenzyme Q (Ubiquinone) concentrations in patients treated with simvastatin G F Watts, C Castelluccio,

C Rice-Evans1057 Septic arthritis and unpasteurised milk P Campbell, S Dealler, J 0 Lawton1059 Abnormal alkaline phosphatase of hepatic type in cerebrospinal fluid of a patient with intracranial metastasis from

lung cancer T Hoshino, K Kumasaka, K Kawano, et al



j.com/

J Clin P


nloaded from

http://jcp.bmj.com/

1061 Cholecystitis, cholelithiasis, and ganglioneuromatosis of the gall bladder: an unusual presentation ofMEN type 2bR Chetty, S P Clark

1064 Rheumatoid arthritis and B cell lymphoma with pathological changes of reactive histiocytosis M Shimada,M Kojima, G Tani, S Komatsumoto, M Nara

1065 Improved immunoturbidimetric method for rheumatoid factor testingM Nykdnen, TPalosuo, KAho, T Sahi,R von Essen

Miscellanea1067 Book Reviews * Notices

No 12 DECEMBER Page

1069

1071

10761080

1085

1089

1093

10971101

11051109

1113

11161120

1124

1126

11291131

11341137

1138

1140114311441155

LeadersAudit of oral anticoagulant treatmnent BCSH Haemostasis and Thrombosis Task Force of the British Society forHaematology B T Colvin, SJ Machin, T WBarrowcliffe, et alHIV and the necropsy S B Lucas

PapersPost mortem examinations of HIV infected patients: a nationwide survey 7 Davies, I P EveraUl, P L LantosNew antiserum against Ki-67 antigen suitable for double immunostaining of paraffin wax sections G Key,J7 Larsen Petersen, MH G Becker, et alImmunohistochemical analysis of Hodgkin's disease using microwave heating C Charalambous, N Singh,P G IsaacsonEffects of single dose compared with three days' prednisolone treatment of healthy volunteers: contrasting effects oncirculating lymphocyte subsets G D Pountain, M T Keogan, B L Hazleman, D L Brownp53 expression in oat and non-oat small cell lung carcinomas: correlations with proliferating cell nuclear antigenP Korkolopoulou, 7 Oates, 7 Crocker, C EdwardsExpression of interleukin-6 by intestinal enterocytes S C Jones, L K Trejdosiewicz, R E Banks, et alRetrospective study of prognostic value ofDNA ploidy and proliferative activity in neuroblastoma SN Huddart,KR Muir, S E Parkes, et alRapid HLA typing by multiplex amplification refractory mutation system P Patel, Y-M D Lo, 7 I Bell, J S WainscoatEstimation of urinary aldosterone using thin-layer chromatography and fluorimetry D Mattingly, H Martin,CM TylerInfluence of anticardiolipin antibodies on immediate patient outcome after myocardial infarction C Raghavan,Jf Ditchfield, R J Taylor, MR Haeney, P C BarnesSerological investigation into the association between Streptococcus bovis and colonic cancer R Darjee, A P GibbComparison of three serological methods for diagnosing Mycoplasma pneumoniae infectionM Karppelin,K Hakkarainen, M Kleemola, A Miettinen

Short reportsAntimicrobial activity of cytotoxic drugs may influence isolation of bacteria and fungi from blood cultures VPeiris,B A OppenheimComparison of three cell cycle associated antigens as markers of proliferative activity and prognosis in breastcarcinoma C E Gillett, DM Barnes, R S CamplejohnFatal vertebral giant cell arteritisMM Sheehan, C Keohane, C TwomeyRenal failure caused by leukaemic infiltration in chronic lymphocytic leukaemia 7K Phillips, P S Bass, G Majumdar,D R Davies, N F3rones, T C PearsonGlanzmann's thrombasthenia with mild von Willebrand's disease R Nounou, D SpenceAnalysis of human herpes virus-6 genomes in lymphoid malignancy in Japan Y Sumiyoshi, M Kikuchi, K Ohshima,M Takeshita, YEizuru, YMinamishimaInaccurate haemoglobin estimation in Waldenstrom's macroglobulinaemia: unusual reaction with monomeric IgMparaprotein M3' Goodrick, R J7 Boon, R J7 D Bishop, JA Copplestone, A G PrenticeMiscellaneaCorrespondence * Book reviews - NoticesList of assessorsAnnual author index to Volume 46Annual subject index to Volume 46Annual contents index to Volume 46



j.com/

J Clin P


nloaded from

http://jcp.bmj.com/

fuliniual pathology - jcp.bmj.com · 113 medullarycarcinoma ofthethyroidwithcarcinoid-like features...

Documents